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61. 发明申请

US20090006007A1 SYSTEM AND METHOD FOR MEASURING MACHINE ROLLING RESISTANCE 有权
标题翻译：用于测量机器耐磨性的系统和方法
公开(公告)号：US20090006007A1
公开(公告)日：2009-01-01
申请号：US11819879
申请日：2007-06-29
申请人： Jonny R. Greiner , Yang Liu
发明人： Jonny R. Greiner , Yang Liu
IPC分类号： G01M13/00 , G01M17/00
CPC分类号： G01M17/02
摘要： A method of measuring rolling resistance of a machine is disclosed. The method may include determining a drive axle torque value of the machine and calculating a total effective grade value using the drive axle torque value. The method may further include determining at least one drivetrain efficiency loss factor value and calculating a total drivetrain efficiency loss value of the machine using the at least one drivetrain efficiency loss factor value. The method may also include determining position data of the machine and calculating an actual grade value based on the position data. The method may additionally include calculating a rolling resistance value of the machine by subtracting the actual grade value and the drivetrain efficiency loss value from the total effective grade value and outputting the rolling resistance value.
摘要翻译：公开了一种测量机器滚动阻力的方法。该方法可以包括确定机器的驱动轴扭矩值并使用驱动轴扭矩值计算总有效等级值。该方法还可以包括使用至少一个传动系效率损失因子值来确定至少一个传动系效率损失因子值并计算机器的总传动系效率损失值。该方法还可以包括确定机器的位置数据并基于位置数据计算实际坡度值。该方法可以另外包括通过从总有效等级值中减去实际坡度值和传动系效率损失值并输出滚动阻力值来计算机器的滚动阻力值。

62. 发明申请

US20080037024A1 Systems, methods, and apparatuses of low-coherence enhanced backscattering spectroscopy 有权
标题翻译：低相干增强后向散射光谱的系统，方法和装置
公开(公告)号：US20080037024A1
公开(公告)日：2008-02-14
申请号：US11803029
申请日：2007-05-11
申请人： Vadim Backman , Hermant Roy , Young Kim , Yang Liu , Vladimir Turzhitsky , Jeremy Rogers
发明人： Vadim Backman , Hermant Roy , Young Kim , Yang Liu , Vladimir Turzhitsky , Jeremy Rogers
IPC分类号： G01N21/47
CPC分类号： G01J3/4412 , G01J3/02 , G01J3/0221 , G01J3/0224 , G01J3/10 , G01N21/31 , G01N21/47 , G01N2021/4709
摘要： Systems, methods, and apparatuses of low-coherence enhanced backscattering spectroscopy are described within this application. One embodiment includes providing incident light comprising at least one spectral component having low coherence, wherein the incident light is to be illuminated on a target object in vivo. An intensity of one or more of at least one spectral component and at least one angular component of backscattering angle of backscattered light is recorded, wherein the backscattered light is to be backscattered from illumination of the incident light on the target object and wherein the backscattering angle is an angle between incident light propagation direction and backscattered light propagation direction. The intensity of the at least one spectral component and the at least one backscattering angle of backscattered light is analyzed, to obtain one or more optical markers of the backscattered light, toward evaluating said properties.
摘要翻译：本申请中描述了低相干增强后向散射光谱的系统，方法和装置。一个实施例包括提供包括具有低相干性的至少一个光谱分量的入射光，其中入射光将在体内照射在目标物体上。记录至少一个光谱分量中的一个或多个光束分量和至少一个后向散射光的后向散射角度的角度分量的强度，其中后向散射光将从目标物体上入射光的照射反向散射，并且其中后向散射角是入射光传播方向和反向散射光传播方向之间的角度。分析至少一个光谱分量的强度和背散射光的至少一个后向散射角度，以获得反向散射光的一个或多个光学标记，以评估所述性质。

63. 发明申请

US20070223398A1 Method for Implementing Grouping Devices and Interacting Among Grouped Devices 有权
标题翻译：分组设备实现方法和分组设备间的交互
公开(公告)号：US20070223398A1
公开(公告)日：2007-09-27
申请号：US11568443
申请日：2005-01-21
申请人： Yujin Luo , Yang Liu , Mingliang Guo
发明人： Yujin Luo , Yang Liu , Mingliang Guo
IPC分类号： H04L12/28
CPC分类号： H04W4/08 , H04L63/0807 , H04L67/1046 , H04L2463/062 , H04W8/186 , H04W12/04 , H04W12/06 , H04W84/18
摘要： The present invention discloses a method for implementing device grouping and interactions between grouped devices. In a network, a device creating a device group sends an advertisement message carrying identification information of a device group to which it belongs, to the network. After receiving the advertisement message, a network device which wants to join in the corresponding device group joins in the device group identified by the corresponding advertisement message. When two network devices interact with each other, the method further comprises: sending by an initiating device, an access request to an accessed device; judging by the device receiving the access request, whether the device sending the request is a trusted device thereof or not, if so, interacting by both parties with each other; otherwise, denying the access request, or determining a common trusted third party together with the initiating device; acquiring by the initiating device, key information of the accessed device from the common trusted third party, and interacting with the accessed device by using the acquired key information. The method can support one and the same device to join in deferent groups while facilitating the device management, and can achieve secure authentication based communication interactions between any devices.
摘要翻译：本发明公开了一种用于实现分组设备之间的设备分组和交互的方法。在网络中，创建设备组的设备向网络发送携带其所属的设备组的标识信息的广播消息。在接收到广告消息之后，希望加入相应设备组的网络设备加入由相应广告消息标识的设备组中。当两个网络设备彼此交互时，该方法还包括：由发起设备向被访问设备发送访问请求; 由接收到访问请求的设备判断，发送请求的设备是否是可信设备，如果是，则由双方互相交互; 否则拒绝访问请求，或者与发起设备一起确定公共可信第三方; 由所述发起设备从所述公共受信任的第三方获取所访问设备的密钥信息，并且通过使用所获取的密钥信息与所访问的设备进行交互。该方法可以支持同一设备加入不同的组，同时方便设备管理，并且可以实现任何设备之间基于安全认证的通信交互。

64. 发明申请

US20060122184A1 Cyanomethyl derivatives as cysteine protease inhibitors 审中-公开
标题翻译：氰甲基衍生物作为半胱氨酸蛋白酶抑制剂
公开(公告)号：US20060122184A1
公开(公告)日：2006-06-08
申请号：US10536889
申请日：2003-11-26
申请人： Michael Graupe , Agnes Lau , John Link , Yang Liu , Craig Mossman , John Patterson , Sheila Zipfel
发明人： Michael Graupe , Agnes Lau , John Link , Yang Liu , Craig Mossman , John Patterson , Sheila Zipfel
IPC分类号： A61K31/53 , A61K31/50 , A61K31/4965 , A61K31/421 , A61K31/381 , A61K31/277 , A61K31/415
CPC分类号： C07C255/25 , A61K38/00 , C07D211/66 , C07D213/82 , C07D277/30 , C07D333/40 , C07K5/06139
摘要： The present invention is directed to cyanomethyl derivatives that are inhibitors of cysteine protease, in particular, cathepsin B, K, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
摘要翻译：本发明涉及作为半胱氨酸蛋白酶，特别是组织蛋白酶B，K，F和S的抑制剂的氰甲基衍生物，因此可用于治疗由这些蛋白酶介导的疾病。本发明涉及包含这些化合物的药物组合物及其制备方法。

65. 发明申请

US20050204414A1 Methods of blocking tissue destruction by autoreactive T cells 审中-公开
标题翻译：通过自身反应性T细胞阻断组织破坏的方法
公开(公告)号：US20050204414A1
公开(公告)日：2005-09-15
申请号：US11128496
申请日：2005-05-13
申请人： Yang Liu , Pan Zheng , Xuefeng Bai , Xingluo Liu
发明人： Yang Liu , Pan Zheng , Xuefeng Bai , Xingluo Liu
IPC分类号： A61K38/00 , A61K38/095 , A61K39/00 , C07K14/705 , C07K16/28 , A01K67/027 , C07H21/04 , A61K39/395 , C07K14/74
CPC分类号： A61K38/177 , A61K38/00 , A61K39/0008 , C07K14/70596 , C07K16/2896 , C07K2319/00 , C07K2319/30
摘要： Methods of reducing autoreactive T cell-initiated destruction of tissues in a mammal, comprising: administering to a mammal a CD24 antisense molecule or a polynucleotide coding for the same, wherein the CD24 antisense molecule or polynucleotide is administered to the mammal by an ex vivo or in vivo procedure.
摘要翻译：减少哺乳动物组织中自身反应性T细胞起始破坏的方法，包括：向哺乳动物施用CD24反义分子或编码其的多核苷酸，其中所述CD24反义分子或多核苷酸通过离体或体内程序。

66. 发明申请

US20050204413A1 Methods of blocking tissue destruction by autoreactive T cells 审中-公开
标题翻译：通过自身反应性T细胞阻断组织破坏的方法
公开(公告)号：US20050204413A1
公开(公告)日：2005-09-15
申请号：US11128495
申请日：2005-05-13
申请人： Yang Liu , Pan Zheng , Xuefeng Bai , Xingluo Liu
发明人： Yang Liu , Pan Zheng , Xuefeng Bai , Xingluo Liu
IPC分类号： A61K38/00 , A61K38/095 , A61K39/00 , C07K14/705 , C07K16/28 , A01K67/027 , C07H21/04 , A61K39/395 , C12N15/09 , C07K14/74
CPC分类号： A61K38/177 , A61K38/00 , A61K39/0008 , C07K14/70596 , C07K16/2896 , C07K2319/00 , C07K2319/30
摘要： Methods of reducing autoreactive T cell-initiated destruction of tissues in a mammal, comprising administering to the mammal a CD24 dsRNAi molecule or a polynucleotide that encodes a CD24 dsRNAi molecule, wherein said molecule or polynucleotide is administered to the mammal by an ex vivo or in vivo procedure.
摘要翻译：减少哺乳动物组织自身反应性T细胞破坏的方法，包括向哺乳动物施用CD24 dsRNAi分子或编码CD24 dsRNAi分子的多核苷酸，其中所述分子或多核苷酸通过离体或体内过程。

67. 发明授权

US11039090B2 Multipurpose imaging and display system 有权
公开(公告)号：US11039090B2
公开(公告)日：2021-06-15
申请号：US16599850
申请日：2019-10-11
申请人： Yang Liu
发明人： Yang Liu
IPC分类号： H04N5/33 , H04N13/204 , A61B5/00 , A61B5/0205 , A61B5/1455 , G02B27/01 , H04N7/15
摘要： A multi-purpose imaging and display system includes a display; a detector coupled to the display and having a field of view; and a filter communicating with the detector. The field of view is imaged by the detector through the filter, the filter configured to be sensitive to a first frequency spectrum, so the detector displays only objects within the field of view on the detector that emit one or more frequencies within the first frequency spectrum. The detector and filter can work together in different operational states or modes for acquiring image data of a target object under investigation. A computing device can be included to process acquired image data, and communication interfaces can be employed to achieve networking of multiple systems. A peripheral interface allows a plurality of peripheral devices to be selectively added to tailor the data acquisition and display capabilities of the imaging and display system.

68. 发明授权

US10924670B2 System and apparatus for co-registration and correlation between multi-modal imagery and method for same 有权
公开(公告)号：US10924670B2
公开(公告)日：2021-02-16
申请号：US15952909
申请日：2018-04-13
申请人： Yang Liu , Maziyar Askari Karchegani
发明人： Yang Liu , Maziyar Askari Karchegani
IPC分类号： H04N5/232 , G06T7/33 , H04N13/25 , H04N5/225 , H04N13/246 , H04N17/00 , H04N13/271 , G06T7/38 , H04N5/33 , H04N5/235 , G06T7/593
摘要： The present disclosure provides an image capturing device that captures images of a first sensor that includes a first imaging modality, a second sensor that includes a first imaging modality and a third sensor that includes a second imaging modality. A controller connected with the first sensor, the second sensor and the third sensor, wherein the controller registers an image captured by the first sensor or the second sensor to an image captured by the third sensor.

69. 发明申请

US20210038189A1 METHODS AND APPARATUSES FOR COLLECTION OF ULTRASOUND IMAGES 有权
公开(公告)号：US20210038189A1
公开(公告)日：2021-02-11
申请号：US16987999
申请日：2020-08-07
申请人： Yang Liu , Cristina Shin , Nathan Silberman , Audrey Howell , Daniel Hertz , Swaminathan Sankaranarayanan
发明人： Yang Liu , Cristina Shin , Nathan Silberman , Audrey Howell , Daniel Hertz , Swaminathan Sankaranarayanan
IPC分类号： A61B8/00 , A61B5/20 , A61B8/08
摘要： Aspects of the technology described herein include determining, during ultrasound imaging, that an anatomical region is clipped by a field of view of an ultrasound image, and providing a notification, during the ultrasound imaging, that the anatomical region is clipped by the field of view of the ultrasound image. Aspects of the technology described herein also include determining that an anatomical region is clipped by a field of view of at least one ultrasound image collected during a three-dimensional ultrasound imaging sweep, and providing a notification that the anatomical region is clipped by the field of view of the at least one ultrasound image collected during the three-dimensional ultrasound imaging sweep.

70. 发明授权

US10849710B2 Imaging and display system for guiding medical interventions 有权
公开(公告)号：US10849710B2
公开(公告)日：2020-12-01
申请号：US15118139
申请日：2014-10-27
申请人： Yang Liu
发明人： Yang Liu
IPC分类号： A61B5/05 , A61B90/00 , A61B90/20 , A61B34/20 , A61B90/50 , A61B90/30
摘要： An imaging and display system for guiding medical interventions includes a wearable display, such as a goggle display, for viewing by a user. The display presents a composite, or combined image that includes pre-operative surgical navigation images, intraoperative images, and in-vivo microscopy images or sensing data. The pre-operative images are acquired from scanners, such as MRI and CT scanners, while the intra-operative images are acquired in real-time from a camera system carried by the goggle display for imaging the patient being treated so as to acquire intraoperative images, such as fluorescence images. A probe, such as a microscopy probe or a sensing probe, is used to acquire in-vivo imaging/sensing data from the patient. Additionally, the intra-operative and in-vivo images are acquired using tracking and registration techniques to align them with the pre-operative image and the patient to form a composite image for display by the goggle display.

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