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61. 发明申请

US20050043290A1 Cyclic amine BACE-1 inhibitors having a heterocyclic substituent 有权
标题翻译：具有杂环取代基的环胺BACE-1抑制剂
公开(公告)号：US20050043290A1
公开(公告)日：2005-02-24
申请号：US10911030
申请日：2004-08-04
申请人： Jared Cumming , Ying Huang , Guoqing Li , Ulrich Iserloh , Andrew Stamford , Corey Strickland , Johannes Voigt , Yusheng Wu , Jianping Pan , Tao Guo , Douglas Hobbs , Thuy Le , Jeffrey Lowrie
发明人： Jared Cumming , Ying Huang , Guoqing Li , Ulrich Iserloh , Andrew Stamford , Corey Strickland , Johannes Voigt , Yusheng Wu , Jianping Pan , Tao Guo , Douglas Hobbs , Thuy Le , Jeffrey Lowrie
IPC分类号： C07D207/26 , C07D207/277 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , A61K31/55 , C07D43/02
CPC分类号： C04B35/632 , C07D207/277 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14
摘要： Disclosed are novel compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1 is X is —O—, —C(R14)2— or —N(R)—; Z is —C(R14)2— or —N(R)—; t is 0, 1, 2 or 3; each R and R2 is independently H, alkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, alkenyl or alkynyl; each R14 is H, alkyl, alkenyl, alkynyl, halo, —CN, haloalkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, —OR35, —N(R24)(R25) or —SR35; R41 is alkyl, cycloalkyl, —SO2(alkyl), —C(O)-alkyl, —C(O)-cycloalkyl or -alkyl-NH—C(O)CH3; and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I and methods of treating cognitive or neurodegenerative diseases with compounds of formula I. Also disclosed are pharmaceutical compositions and methods of treatment comprising compounds of formula I in combination with other agents useful in treating cognitive or neurodegenerative diseases.
摘要翻译：公开了下式的新化合物或其药学上可接受的盐或溶剂化物，其中R 1是X是-O - ， - C（R 14）2 - 或-N（R） - ; Z是-C（R 14）2 - 或-N（R） - ; t为0,1,2或3; 每个R和R 2独立地是H，烷基，环烷基，环烷基烷基，芳基，杂芳基，杂环烷基，芳基烷基，杂芳基烷基，杂环烷基烷基，烯基或炔基; 每个R 14是H，烷基，烯基，炔基，卤素，-CN，卤代烷基，环烷基，环烷基烷基，芳基，杂芳基，杂环烷基，芳基烷基，杂芳基烷基，杂环烷基烷基，-OR 35，-N（R 24））（R 25）或-SR 35; R 41是烷基，环烷基，-SO 2（烷基），-C（O） - 烷基，-C（O） - 环烷基或 - 烷基-NH-C（O）CH 3; 其余变量如本说明书中所定义。还公开了包含式I化合物的药物组合物和用式I化合物治疗认知障碍或神经变性疾病的方法。还公开了药物组合物和治疗方法，其包含式I化合物与用于治疗认知或神经变性的其它药剂疾病

62. 发明授权

US09723342B2 Method and apparatus for low jitter clock recovery in wireless display extensions 有权
公开(公告)号：US09723342B2
公开(公告)日：2017-08-01
申请号：US13996621
申请日：2011-12-21
申请人： Guoqing Li , Joseph A. Bennett , Gideon Prat , Solomon B. Trainin , Sang-Hee Lee , Vallabhajosyula Z. Somayazulu , George R. Hayek , Pat Brouillette , Dmitrii A. Loukianov
发明人： Guoqing Li , Joseph A. Bennett , Gideon Prat , Solomon B. Trainin , Sang-Hee Lee , Vallabhajosyula Z. Somayazulu , George R. Hayek , Pat Brouillette , Dmitrii A. Loukianov
IPC分类号： H04N21/242 , H04N21/236 , H04N21/61 , H04N21/43
CPC分类号： H04N21/242 , H04N21/23608 , H04N21/4305 , H04N21/6131
摘要： An approach is provided for determining a program clock reference (PCR) value validity, for avoiding inaccurate variable delay reference (VDR) values, and for avoiding a mismatch in a data packet between a sequence number and a packet number for a wireless display extension. The approach involves determining to generate a data packet carrier having an optional PCR value, a VDR) value, and a validity indicator. The approach may further involve processing the data packet carrier to determine whether the data packet carrier has the optional PCR value. The approach may also involve causing, at least in part, a surrogate PCR value to be generated based, at least in part, on a determined absence of the optional PCR value from the data packet carrier.

63. 发明申请

US20170174693A1 SOLUBLE GUANYLATE CYCLASE STIMULATORS 审中-公开
公开(公告)号：US20170174693A1
公开(公告)日：2017-06-22
申请号：US15384429
申请日：2016-12-20
申请人： Raphaelle Berger , Yi-Heng Chen , Guoqing Li , Joie Garfunkle , Hong-Dong Li , Shouwu Miao , Subharekha Raghavan , Cameron J. Smith , John Stelmach , Alan Whitehead , Rui Zhang , Yong Zhang , Jianmin Fu , Gang Ji , Falong Jiang
发明人： Raphaelle Berger , Yi-Heng Chen , Guoqing Li , Joie Garfunkle , Hong-Dong Li , Shouwu Miao , Subharekha Raghavan , Cameron J. Smith , John Stelmach , Alan Whitehead , Rui Zhang , Yong Zhang , Jianmin Fu , Gang Ji , Falong Jiang
IPC分类号： C07D487/04 , A61K31/519 , C07D519/00 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D519/00
摘要： The invention provides compounds of the Formula (I) or a pharmaceutically acceptable salts thereof, wherein X, Y, Z, R1, R2, R4, Ra, and the subscripts m, p, and q are as described herein. The compounds or their pharmaceutically acceptable salts can modulate the body's production of cyclic guanosine monophosphate (“cGMP”), and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose.

64. 发明申请

US20170150540A1 WI-FI DIRECT SERVICES MECHANISMS FOR WIRELESS GIGABIT DISPLAY EXTENSION 审中-公开
公开(公告)号：US20170150540A1
公开(公告)日：2017-05-25
申请号：US15396521
申请日：2016-12-31
申请人： Guoqing Li , Bahareh Sadeghi , Emily Qi , Carlos Cordeiro
发明人： Guoqing Li , Bahareh Sadeghi , Emily Qi , Carlos Cordeiro
IPC分类号： H04W76/02 , H04L29/08 , H04W8/00
CPC分类号： H04W76/14 , H04L67/104 , H04L67/141 , H04L67/143 , H04L2212/00 , H04W8/005 , H04W76/10 , H04W84/12
摘要： Techniques for implementing Wireless Gigabit (WiGig) Display Extension (WDE) communications as Wi-Fi Direct Services (WFDS) services are described. According to such techniques, WDE services may make use of primitives and events obtained from a WFDS application service platform (ASP). This application of WFDS to WDE may provide necessary mechanisms for layer 2 operations such as device and service discovery, P2P connection management, and session management. Other embodiments are described and claimed.

65. 发明授权

US09210617B2 Method and user equipment for sending uplink resource scheduling request 有权
标题翻译：发送上行资源调度请求的方法和用户设备
公开(公告)号：US09210617B2
公开(公告)日：2015-12-08
申请号：US13498682
申请日：2010-09-15
申请人： Xueming Pan , Guoqing Li , Yanan Lin
发明人： Xueming Pan , Guoqing Li , Yanan Lin
IPC分类号： H04J3/00 , H04W28/18 , H04W24/02 , H04W48/16
CPC分类号： H04W72/1289 , H04L5/14 , H04L5/1469 , H04W24/02 , H04W28/18 , H04W48/16 , H04W72/1284
摘要： A method for a user equipment sending an uplink resource scheduling request in a long term evolution mobile communication system and the user equipment thereof are provided. The present invention relates to a technique for the user equipment sending the uplink resource scheduling request in a long term evolution system, for reducing the user data transmission delay. The embodiments of the present invention set the minimum alternative option of the scheduling request transmission cycle configuration parameter as 2 ms or 1 ms, that is to say, add 2 ms or 1 ms, or 2 ms and 1 ms to the alternative option of the scheduling request transmission cycle configuration parameter, therefore, improving the flexibility of the whole system in the scheduling request transmission cycle configuration. When the data delay is required to be less, the user data transmission delay can be reduced, by using the 2 ms or 1 ms scheduling request transmission cycle configuration, to the delay requirement of 10 ms as close as possible.
摘要翻译：提供了一种用于在长期演进移动通信系统及其用户设备中发送上行资源调度请求的用户设备的方法。本发明涉及一种用于在长期演进系统中发送上行资源调度请求的用户设备，用于减少用户数据传输延迟的技术。本发明的实施例将调度请求传输周期配置参数的最小替代选项设置为2ms或1ms，也就是说，将补码选项的2 ms或1 ms，或2ms和1 ms添加到调度请求传输周期配置参数，因此，提高整个系统在调度请求传输周期配置中的灵活性。当数据延迟要求较小时，可以通过使用2ms或1ms调度请求传输周期配置来减少用户数据传输延迟，尽可能接近10 ms的延迟要求。

66. 发明授权

US08876823B2 Steel plate for funnel chest orthopaedic surgery 有权
标题翻译：漏斗胸矫形手术钢板
公开(公告)号：US08876823B2
公开(公告)日：2014-11-04
申请号：US13259785
申请日：2010-05-26
申请人： Guoqing Li , Ju Mei , Deyu Zhu
发明人： Guoqing Li , Ju Mei , Deyu Zhu
IPC分类号： A61B17/58 , A61B17/80
CPC分类号： A61B17/8076 , Y10S606/905
摘要： A steel plate for funnel chest orthopaedic surgery includes a supporting plate (1), a fixing piece (2), a telescopic fixing piece (3), a guiding head (4) and screws (6). The supporting plate (1) is an elongate steel plate. One end of the supporting plate (1) is designed to be integrated with the fixing piece (2), and the other end is provided with a size-adjusting strap (5). The telescopic fixing piece (3) is an elongate steel plate with the same width as that of the supporting plate (1). One end of the telescopic fixing piece (3) is designed to be integrated with the fixing piece (2), and the other end is provided with a groove. The guiding head (4) is an elongate steel plate with the same width as that of the supporting plate (1). One end of the guiding head (4) is provided with a hook, and the other end is provided with a groove.
摘要翻译：用于漏斗胸骨科手术的钢板包括支撑板（1），固定件（2），伸缩固定件（3），引导头（4）和螺钉（6）。支撑板（1）是细长钢板。支撑板（1）的一端设计成与固定片（2）成一体，另一端设有尺寸调节带（5）。伸缩固定片（3）是与支撑板（1）的宽度相同的细长钢板。伸缩式固定件（3）的一端设计成与固定件（2）成一体，另一端设有槽。引导头（4）是与支撑板（1）的宽度相同的细长钢板。引导头（4）的一端设有钩，另一端设有槽。

67. 发明申请

US20140294106A1 IMPLEMENTING MIMO IN MMWAVE WIRELESS COMMUNICATION SYSTEMS 有权
标题翻译：在MMWAVE无线通信系统中实现MIMO
公开(公告)号：US20140294106A1
公开(公告)日：2014-10-02
申请号：US13992753
申请日：2011-12-08
申请人： Carlos Cordeiro , Guoqing Li , Vallabhajosyula Z. Somayazulu , Bahareh B. Sadeghi , Ali S. Sadri
发明人： Carlos Cordeiro , Guoqing Li , Vallabhajosyula Z. Somayazulu , Bahareh B. Sadeghi , Ali S. Sadri
IPC分类号： H04B7/04
CPC分类号： H04B7/0413 , H04B7/0452 , H04B7/0617 , H04B7/0691 , H04L5/0023 , H04W76/00
摘要： A system and method are provided to increase data rates available in mmWave wireless communication systems by adapting a multiple-input multiple-output (MIMO) in a next generation mmWave wireless communication system. The system and method advantageously employ the characteristics of mmWave antenna arrays, including multiple antenna elements in each antenna array, to implement the MIMO scheme by establishing multiple beamformed communication links between a mmWave transmitter and receiver. An outgoing signal is divided into multiple signal elements to correspond to the multiple beamformed links and each of the multiple signal elements is transmitted by the transmitter across a different one of the multiple beamformed links to be reassembled at the receiver. An antenna element allocation scheme is incorporated to assign specific numbers and configurations of antenna elements at each of the transmitted and receiver to each of the multiple beamformed communication links.
摘要翻译：提供了一种通过在下一代mmWave无线通信系统中适配多输入多输出（MIMO）来增加mmWave无线通信系统中的可用数据速率的系统和方法。该系统和方法有利地采用了包括在每个天线阵列中的多个天线元件的mmWave天线阵列的特征，以通过在mmWave发射机和接收机之间建立多个波束形成的通信链路来实现MIMO方案。输出信号被分成多个信号元件以对应于多个波束形成的链路，并且多个信号元素中的每一个由发射机跨越多个波束形成的链路中的不同的一个发射，以在接收机处重新组合。并入天线元件分配方案，以将发送和接收的每个天线元件的特定数量和配置分配给多个波束形成的通信链路中的每一个。

68. 发明申请

US20140233556A1 IMPLEMENTING AN ASSISTED CROSS-PROTOCOL ADAPTATION LAYER/CROSS-LAYER CLOCK SYNCHRONIZATION SCHEME 有权
标题翻译：实施协助交叉协议适配层/跨层时钟同步方案
公开(公告)号：US20140233556A1
公开(公告)日：2014-08-21
申请号：US13995690
申请日：2011-12-22
申请人： Guoqing Li , Bahareh Sadeghi , Carlos Cordeiro
发明人： Guoqing Li , Bahareh Sadeghi , Carlos Cordeiro
IPC分类号： H04W56/00
CPC分类号： H04W56/001 , H04W56/0035
摘要： A system and method are provided to streamline at least a clock synchronization process for subsequent WiGig PALs once clocks in a first WiGig PAL transmitter and a corresponding first WiGig PAL receiver are synchronized. The unique layering structure of the WiGig 60 GHz standard affords an opportunity to streamline the clock synchronization process based on relationships between individual WiGig PALs, and that the WiGig PALs are directly on top of the WiGig MAC and PHY layers. A process for assisted cross-PAL/cross-layer clock synchronization affords significant reductions in an amount of time required to synchronize the clocks of multiple WiGig PALs based on leveraging an already synchronized clock pair in a first WiGig PAL transmitter/receiver pair to facilitate the clock synchronization of one or more subsequent WiGig PAL transmitter/receiver pairs.
摘要翻译：提供了一种系统和方法，用于在第一WiGig PAL发射机和对应的第一WiGig PAL接收机同步时，一次时钟后续的WiGig PAL的至少一个时钟同步过程。 WiGig 60 GHz标准的独特分层结构提供了一种基于各个WiGig PAL之间的关系简化时钟同步过程的机会，WiGig PAL直接位于WiGig MAC和PHY层之上。基于在第一WiGig PAL发射机/接收机对中利用已经同步的时钟对，辅助的跨PAL /跨层时钟同步的过程提供了使多个WiGig PAL的时钟同步所需的时间量的显着减少，以便于一个或多个后续WiGig PAL发射机/接收机对的时钟同步。

69. 发明授权

US08811433B2 Method, system and device for uplink synchronization 有权
标题翻译：用于上行同步的方法，系统和设备
公开(公告)号：US08811433B2
公开(公告)日：2014-08-19
申请号：US13501062
申请日：2010-09-30
申请人： Yali Zhao , Fangli Xu , Fei Qin , Guoqing Li
发明人： Yali Zhao , Fangli Xu , Fei Qin , Guoqing Li
IPC分类号： H04J3/06 , H04L27/26 , H04L7/00 , H04W56/00
CPC分类号： H04L27/2657 , H04L7/0083 , H04W56/00 , H04W56/0005 , H04W56/0045 , H04W92/10
摘要： A method for uplink synchronization in a multi-carrier system includes the following steps: a base station selects one or more first component carriers, which do not establish the uplink synchronization with the base station, from multiple component carriers supported by a terminal; then the base station obtains Timing Advance (TA) needed by the terminal to perform the uplink transmission on the first component carriers, and sends the TA information to the terminal; the terminal performs the uplink transmission on said first component carriers according to said TA. The application of the present invention enables the establishment of uplink synchronization between the base station and the user equipment in multi-carrier system.
摘要翻译：一种多载波系统中的上行链路同步的方法包括以下步骤：基站从终端支持的多个分量载波中选择不与基站建立上行链路同步的一个或多个第一分量载波; 那么基站获得终端所需的定时提前（TA），以在第一分量载波上执行上行链路传输，并将TA信息发送到终端; 终端根据所述TA在所述第一分量载波上执行上行链路传输。本发明的应用使得能够在多载波系统中建立基站与用户设备之间的上行链路同步。

70. 发明申请

US20140218236A1 USE OF LOCATION INFORMATION IN MULTI-RADIO DEVICES FOR MMWAVE BEAMFORMING 有权
标题翻译：在多波束设备中使用位置信息进行MMWAVE波束形成
公开(公告)号：US20140218236A1
公开(公告)日：2014-08-07
申请号：US13993218
申请日：2011-12-15
申请人： Bahareh B. Sadeghi , Carlos Cordeiro , Guoqing Li , Vallabhajosyula Zulu Somayazulu
发明人： Bahareh B. Sadeghi , Carlos Cordeiro , Guoqing Li , Vallabhajosyula Zulu Somayazulu
IPC分类号： H04B7/00
CPC分类号： H04B7/00 , G01S5/0072 , H04W16/28 , H04W64/00 , H04W88/06
摘要： A system and method are provided for using location services available from other radios in a multi-radio system to assist a beamforming mechanism, particularly in establishing and maintaining mmWave communication link. A majority of wireless client devices for use in a mmWave communication link are equipped with multiple radios. Many of the “other” radios include technologies that support location based services, including GPS, Wi-Fi and cellular communications. One or more non-mmWave in one device is used to provide relative location information regarding the other device with which the mmWave communication link is to be established. The relative location information is used to derive a direction for communication, and to compute beamforming parameters, in a limited set of transmit/receive sectors where the destination device is likely to be found, in order to streamline the beamforming process.
摘要翻译：提供了一种系统和方法，用于使用可从多无线电系统中的其他无线电获得的定位服务来协助波束成形机制，特别是在建立和维护毫米波通信链路中。用于mmWave通信链路的大多数无线客户端设备都配备有多个无线电。许多“其他”无线电包括支持基于位置的服务的技术，包括GPS，Wi-Fi和蜂窝通信。使用一个设备中的一个或多个非mm波形来提供关于要建立mmWave通信链路的另一个设备的相对位置信息。相对位置信息用于导出用于通信的方向，并且在可能找到目的地设备的发送/接收扇区的有限集合中计算波束成形参数，以便简化波束成形处理。

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