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61. 发明授权

US5622832A Arachidonic acid releasing phospholipase A2 enzyme and methods of use 失效
标题翻译：花生四烯酸释放磷脂酶A2酶及使用方法
公开(公告)号：US5622832A
公开(公告)日：1997-04-22
申请号：US486628
申请日：1990-02-28
申请人： John L. Knopf , James Clark
发明人： John L. Knopf , James Clark
IPC分类号： A61K38/00 , C12N9/20 , C12N15/55 , C12Q1/44
CPC分类号： C12N9/20 , A61K38/00
摘要： The invention provides novel DNA and peptide sequences encoding a family of phospholipase A.sub.2 enzymes, with specific activities of approximately 20 .mu.mol/min/mg in the mixed micelle assay. These enzymes are useful in methods for detecting the anti-inflammatory potential of various chemical agents. The invention also details novel methods for determining such potential using the novel sequences, methods for making the novel peptides, and methods for developing new anti-inflammatory drugs.
摘要翻译：本发明提供了编码磷脂酶A2酶家族的新型DNA和肽序列，在混合胶束测定中具有约20μmol/ min / mg的比活性。这些酶可用于检测各种化学试剂的抗炎潜力的方法。本发明还详细描述了使用新的序列确定这种潜力的新方法，制备新肽的方法和开发新的抗炎药的方法。

62. 发明授权

US5420408A Reagent bottle identification method 失效
标题翻译：试剂瓶识别方法
公开(公告)号：US5420408A
公开(公告)日：1995-05-30
申请号：US241469
申请日：1994-05-12
申请人： Bruce Weyrauch , Norman Kelln , Leon Schmidt , Charles Butts , James Clark , Kelsey Loughlin , Gary Richardson
发明人： Bruce Weyrauch , Norman Kelln , Leon Schmidt , Charles Butts , James Clark , Kelsey Loughlin , Gary Richardson
IPC分类号： G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G06K19/06 , G09F3/02 , G06K7/10
CPC分类号： G01N35/00663 , G01N35/025 , G06K19/06037 , G09F3/0297 , G01N2035/00356 , G01N2035/00425 , G01N2035/00673 , G01N2035/0446 , G01N35/1004 , G01N35/1079 , G06K2019/06253 , G06K2019/06262
摘要： An automatic chemical analyzer utilizes reagents supplied in reagent bottles. The reagent bottles are labeled on their bottom surfaces with an identification label bearing a machine-readable identification code. The automatic chemical analyzer includes a reagent tray having a plurality of tray apertures therein which receive coded reagent bottles and which expose the bottom surface of each bottle for optical viewing of the machine-readable identification code. The analyzer further includes optical scanner means positioned below the reagent tray for reading the machine-readable identification code on the bottom surfaces of reagent bottles within the tray apertures. The tray apertures are selectively located over the optical scanner means so that the analyzer can identify the reagent bottle and the contents thereof.The identification label has a spaced pair of position reference dots defining and orienting a label area. A plurality of bit fields surround the position reference dots, their positions being defined by the position reference dots. Each bit field maps to a single bit of a multi-bit binary bottle identification code. Bit dots are printed in selected bit fields to define the binary value of each bit of the multi-bit binary identification code.
摘要翻译：自动化学分析仪利用试剂瓶中提供的试剂。试剂瓶在其底部表面上标有带有机器可读识别码的识别标签。自动化学分析仪包括其中具有多个托盘孔的试剂托盘，其接收编码的试剂瓶，并暴露每个瓶子的底表面以便光学观察机器可识别代码。分析仪还包括位于试剂盘下方的用于读取托盘孔内的试剂瓶底面上的机读识别码的光扫描器装置。托盘孔选择性地位于光学扫描器装置上方，使得分析器可以识别试剂瓶及其内容物。识别标签具有定义和定向标签区域的一对位置参考点。多个位域围绕位置参考点，其位置由位置参考点限定。每个位域映射到多位二进制瓶识别码的单个位。位点被打印在所选位字段中以定义多位二进制识别码的每个位的二进制值。

63. 发明申请

US20190057336A1 non-emergent medical transportation for rural areas lacking road and map infrastructure 审中-公开
公开(公告)号：US20190057336A1
公开(公告)日：2019-02-21
申请号：US15682474
申请日：2017-08-21
申请人： Jeanna Elizabeth Clark , James Clark , Elizabeth Deming Hammar
发明人： Jeanna Elizabeth Clark , James Clark , Elizabeth Deming Hammar
IPC分类号： G06Q10/06 , G06Q50/22 , G01C21/20
摘要： A means of transportation for rural villages in areas that lack roads and street addressing. Motorbike ambulances traverse the roadless terrain enroute to pick up patients from a predetermined location using global position coordinates. The patient can request this non-emergent medical transportation using cellular phone and/or sending physical communication to the nearest established medical clinic. Established clinics are expanding their geographic reach with this novel form of non-emergent medical transportation that can service rural areas that lack road and map infrastructure.

64. 发明申请

US20100169503A1 Content Tagging of Media Streams 有权
标题翻译：媒体流的内容标记
公开(公告)号：US20100169503A1
公开(公告)日：2010-07-01
申请号：US12344719
申请日：2008-12-29
申请人： Kurt Kollmansberger , Michael Keohane , William VerSteeg , James Clark
发明人： Kurt Kollmansberger , Michael Keohane , William VerSteeg , James Clark
IPC分类号： G06F15/16
CPC分类号： H04L65/605 , H04L67/2804
摘要： In one embodiment, a network device comprises a tag processor configured to process a media stream received at the network device. The media stream is sent through a network to a desired destination. The tag processor comprises at least one of a tag inserter module and a tag module. The tag inserter module inserts a tag into the media stream, the tag indicating content of the media stream and the network device providing the tag. The tag module identifies and reports a value of a tag received within the media stream, and forwards the media stream to a user and/or compares the identified value to an expected tag value, and forwards the media stream to a user in the event that the comparison indicates a match. The present invention embodiments further include a method and logic for content tagging of the media stream.
摘要翻译：在一个实施例中，网络设备包括被配置为处理在网络设备处接收的媒体流的标签处理器。媒体流通过网络发送到所需目的地。标签处理器包括标签插入器模块和标签模块中的至少一个。标签插入器模块将标签插入到媒体流中，标签指示媒体流的内容和提供标签的网络设备。标签模块识别并报告在媒体流内接收到的标签的值，并将媒体流转发给用户和/或将所识别的值与期望的标签值进行比较，并且在以下情况下将媒体流转发给用户：比较表示匹配。本发明实施例还包括用于媒体流的内容标记的方法和逻辑。

65. 发明申请

US20070166430A1 BREATH FRESHENING CONFECTIONERY PRODUCTS AND METHODS OF MAKING AND USING SAME 审中-公开
标题翻译： BREATH FRESHENING CONFECTIONERY产品及其制造和使用方法
公开(公告)号：US20070166430A1
公开(公告)日：2007-07-19
申请号：US11550940
申请日：2006-10-19
申请人： Barbara Stawski , Thomas Mindak , Philip Soukup , Gordon McGrew , James Clark , Michael Haas , Miguel Perez
发明人： Barbara Stawski , Thomas Mindak , Philip Soukup , Gordon McGrew , James Clark , Michael Haas , Miguel Perez
IPC分类号： A23G4/00
CPC分类号： A61B17/50 , A23G3/34 , A23G3/362 , A23G3/38 , A23G3/42 , A23G3/50 , A23G3/54 , A23G4/20 , A23V2002/00 , A61B17/244 , A61K8/0233 , A61K2800/28 , A61K2800/92 , A61Q11/00 , A23V2250/642 , A23V2250/6412 , A23V2250/2482 , A23V2250/242 , A23V2250/161
摘要： A confectionery product comprises a first side and a second side generally opposite to the first side; the second side comprising an abrasive surface that is suitable for scrubbing the top surface of a tongue within the oral cavity. In preferred embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) by including abrasive inclusions in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive inclusions. The confectionery product is preferably a hard confectionery, but may also be a chewing gum product. A preferred confectionery product comprises a second side with a width and a length, the smallest of which is at least 1.6 times the product thickness. Preferred pressed tablets are made from a compressible composition and have at least one abrasive surface suitable for cleaning the surface of a human tongue in an oral cavity and have a hardness of between about 18 Kp and about 35 Kp.
摘要翻译：糖果产品包括大致与第一侧相对的第一侧和第二侧; 所述第二面包括适于擦洗所述口腔内的舌头的顶表面的研磨表面。在优选实施例中，第一侧是光滑的，并且可以是圆顶形状并且通常适合于嘴的顶部。研磨表面可以通过以下方式提供：1）形成的不平坦表面，2）通过在组成第二表面的组合物中包含磨料夹杂物，或3）形成的，不平坦的表面和磨料夹杂物的组合。糖果产品优选是硬糖果，但也可以是口香糖产品。优选的糖果产品包括具有宽度和长度的第二侧，最小的是产品厚度的1.6倍。优选的压片由可压缩的组合物制成，并且具有至少一个适用于在口腔中清洁人舌表面的研磨表面，其硬度介于约18Kp至约35Kp之间。

66. 发明申请

US20070151887A1 Flexible package with opening feature 有权
标题翻译：灵活包装开启功能
公开(公告)号：US20070151887A1
公开(公告)日：2007-07-05
申请号：US11323628
申请日：2005-12-30
申请人： James Clark , Deborah Hannah , James Marnocha
发明人： James Clark , Deborah Hannah , James Marnocha
IPC分类号： B65D73/00 , A61B19/02
CPC分类号： B65D75/5833 , B65D75/46 , B65D75/545 , B65D77/04 , Y10S206/812
摘要： A flexible package has a top surface, a bottom surface and at least one side wall together defining an interior volume of the package. An opening device is attached to the top surface and is at least in part detachable from the top surface to provide access to the interior volume. An article is secured to the opening device for conjoint movement with the opening device upon detachment of the opening device from the top surface of the package. In another embodiment, a portion of the side wall extends outward beyond the top surface to a free edge. A closure system is operable on the extended portion of the side wall to permit selective closing and opening of the package.
摘要翻译：柔性包装具有顶部表面，底部表面和至少一个限定包装内部体积的侧壁。打开装置附接到顶表面并且至少部分地可从顶部表面拆卸以提供对内部容积的通路。当打开装置与包装的顶表面分离时，物品被固定到打开装置以与打开装置一起运动。在另一个实施例中，侧壁的一部分向外延伸超过顶表面到自由边缘。闭合系统可在侧壁的延伸部分上操作以允许选择性地关闭和打开包装。

67. 发明申请

US20060224461A1 Systems and methods for providing client based photo user interface 审中-公开
标题翻译：提供基于客户端的照片用户界面的系统和方法
公开(公告)号：US20060224461A1
公开(公告)日：2006-10-05
申请号：US11064264
申请日：2005-02-24
申请人： Louis Montulli , James Clark , Jeffrey Whitehead , Jason Harrison , Aleksander Totic , Garrett Blythe
发明人： Louis Montulli , James Clark , Jeffrey Whitehead , Jason Harrison , Aleksander Totic , Garrett Blythe
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q30/0601
摘要： Systems and methods are disclosed for providing a user interface for a set of multimedia assets distributed between a web service and a local client by uploading the set of distributed multimedia assets to the web service from the local client and subsequently updating the set of distributed multimedia assets; automatically synchronizing the set of distributed multimedia assets; and displaying the synchronized set of distributed multimedia assets on the user interface.
摘要翻译：公开了一种系统和方法，用于通过从本地客户端上传一组分布式多媒体资产到web服务并且随后更新一组分布式多媒体资产来为分布在web服务和本地客户端之间的一组多媒体资产提供用户界面 ; 自动同步一组分布式多媒体资产; 并在用户界面上显示同步的分布式多媒体资产集。

68. 发明申请

US20060187833A1 Systems and methods for upload bandwidth management 审中-公开
标题翻译：用于上传带宽管理的系统和方法
公开(公告)号：US20060187833A1
公开(公告)日：2006-08-24
申请号：US11064265
申请日：2005-02-23
申请人： Louis Montulli , James Clark , Jeffrey Whitehead , Jason Harrison , Aleksander Totic , Garrett Blythe
发明人： Louis Montulli , James Clark , Jeffrey Whitehead , Jason Harrison , Aleksander Totic , Garrett Blythe
IPC分类号： H04L12/26 , H04L12/28
CPC分类号： H04L43/0894 , H04L41/0896 , H04L43/0817 , H04L43/16 , H04L67/06 , H04L67/125 , H04L67/322
摘要： Systems and methods are disclosed to control an aggregate load from users to a service to improve overall transmission throughput over a network by measuring and monitoring resource utilization for the service, and maintaining additional resource utilization below a predetermined threshold.
摘要翻译：公开了系统和方法来控制从用户到服务的聚合负载，以通过测量和监视服务的资源利用率以及将额外的资源利用率维持在预定阈值以下来改善网络上的总体传输吞吐量。

69. 发明申请

US20060111926A1 Realizing legally binding business contracts through service management models 有权
标题翻译：通过服务管理模式实现具有法律约束力的业务合同
公开(公告)号：US20060111926A1
公开(公告)日：2006-05-25
申请号：US11153652
申请日：2005-06-15
申请人： David Welsh , Frederick Chong , James Clark , Max Morris
发明人： David Welsh , Frederick Chong , James Clark , Max Morris
IPC分类号： G06Q99/00
CPC分类号： G06Q10/06 , G06Q30/00 , G06Q40/00
摘要： Methods and apparatus for managing business interactions between opposing parties. Business interactions are mapped to service contracts. The service contracts are mapped to machine readable code. The machine readable code is defined by business transaction patterns and service interaction patterns. The machine readable code is consumed by an IT system. Management tasks associated with fulfilling obligations required by the business interactions are generated.
摘要翻译：管理对方之间的业务互动的方法和设备。业务互动映射到服务合同。服务合同映射到机器可读代码。机器可读代码由业务交易模式和服务交互模式定义。机器可读代码由IT系统使用。生成与履行业务交互所要求的义务相关联的管理任务。

70. 发明申请

US20060053027A1 Transport logistics systems and methods 审中-公开
公开(公告)号：US20060053027A1
公开(公告)日：2006-03-09
申请号：US11173188
申请日：2005-07-01
申请人： Glenn Riggs , John Kivela , Robert Shellman , Joseph Rocky , Stanley Bainor , Ralph Brechter , Douglas Clark , James Clark , Jon Clow , Amy Daley , Larry Hu , Louis Indelicato , William Lohan , Michael Naughton , Peter Nelson , Alan Shollenberger , M. Willett , Doug Johnston , Donald Mueller , Michael Michaud , Robert Phaneuf , Joseph Bainor
发明人： Glenn Riggs , John Kivela , Robert Shellman , Joseph Rocky , Stanley Bainor , Ralph Brechter , Douglas Clark , James Clark , Jon Clow , Amy Daley , Larry Hu , Louis Indelicato , William Lohan , Michael Naughton , Peter Nelson , Alan Shollenberger , M. Willett , Doug Johnston , Donald Mueller , Michael Michaud , Robert Phaneuf , Joseph Bainor
IPC分类号： G06Q99/00
CPC分类号： G06Q10/08 , G06Q10/0631 , G06Q10/06316 , G06Q10/06375 , G06Q10/0639 , G06Q10/083 , G06Q10/0833 , G06Q10/0834 , G06Q10/087 , G06Q20/40 , G06Q30/00 , G06Q30/0201 , G06Q50/188
摘要： A logistics system manages the shipments of goods supplied from a plurality of different shippers by a plurality of carriers. It has a variety of modules integrated with each other to perform various functionalities. For example, it may have a purchasing module evaluating proposals by shippers for respective shipments of goods and awarding contracts for the shipments to the plurality of carriers. It may have an optimization module analyzing the proposals and informing the purchasing module if an opportunity exists for at least some of the shipments to be consolidated, in which case at least one contract awarded by the purchasing module is for a consolidated group of the shipments. It may have a contract administration module maintaining information relating to the status of proposals received and contracts awarded by the purchasing module. It may have a scheduling module scheduling shipments according to the awarded contracts. It may also have a shipment management module tracking the status of shipments awarded by the purchasing module and scheduled by said scheduling module. It may further have a financial module authorizing payments according to the status of shipments tracked by the shipment management module are passed between first and second asynchronous clock domains.

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