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61. 发明授权

US07276027B2 System, for monitoring the concentration of analytes in body fluids 有权
标题翻译：系统，用于监测体液中分析物的浓度
公开(公告)号：US07276027B2
公开(公告)日：2007-10-02
申请号：US10467592
申请日：2002-02-02
申请人： Hans-Peter Haar , Hans List
发明人： Hans-Peter Haar , Hans List
IPC分类号： A61B5/00
CPC分类号： G01N33/48764 , A61B5/14503 , A61B5/14514 , A61B5/14532 , A61B5/6849
摘要： The invention concerns a system for monitoring the concentration of analytes in body fluids, in particular in interstitial fluid and comprises a catheter having an implantable region and an outlet opening for withdrawing fluid in particular body fluid. A first and a second analytical zone are contacted sequentially with fluid from the catheter and undergo a detectable change when an analyte is present. The analytical zones can be contacted manually with fluid and also preferably in an automated fashion by means of a device. A system according to the invention additionally has an analytical device for analysing the analytical zones in order to determine the concentration of the analyte on the basis of changes caused by the analyte. A further subject matter of the present invention are catheters for use in systems according to the invention as well as magazines containing test zones.
摘要翻译：本发明涉及用于监测体液中特别是间质液中分析物的浓度的系统，并且包括具有可植入区域和用于排出流体特别是体液的出口的导管。第一和第二分析区域顺序地与来自导管的流体接触并且当存在分析物时经历可检测的变化。分析区域可以手动接触流体，并且还可以通过设备以自动方式接触。根据本发明的系统还具有用于分析分析区域的分析装置，以便基于由分析物引起的变化来确定分析物的浓度。本发明的另一主题是用于根据本发明的系统的导管以及含有测试区的杂志。

62. 发明授权

US06787109B2 Test element analysis system 有权
标题翻译：测试元素分析系统
公开(公告)号：US06787109B2
公开(公告)日：2004-09-07
申请号：US09896965
申请日：2001-06-29
申请人： Hans-Peter Haar , George B. K. Meacham
发明人： Hans-Peter Haar , George B. K. Meacham
IPC分类号： G01N3348
CPC分类号： G01N27/3274
摘要： Analysis system for the analytical investigation of a sample, in particular of a body fluid. It consists of test elements brought into contact, for performing an analysis, with a sample to be investigated, and an evaluation apparatus with a test element support for positioning the test element in a measurement position, as well as a measurement and evaluation electronic device. The measurement and evaluation electronic device of the evaluation apparatus comprises a temperature correction device, in order to take into account the temperature prevailing in the measurement zone during the measurement for the determination of the result of the analysis. The temperature correction unit includes a temperature history imaging device for the currentless tracing of the temperature history before the time of measuring, without consuming electric energy before the time of measuring.
摘要翻译：分析系统用于分析样品，特别是体液的分析。它包括接触的测试元件，用于进行分析的测试元件，以及待测试的样品，以及具有用于将测试元件定位在测量位置的测试元件支撑的评估设备，以及测量和评估电子设备。评估装置的测量和评估电子装置包括温度校正装置，以便在测量期间考虑测量区域中存在的用于确定分析结果的温度。温度校正单元包括用于在测量之前无电流跟踪温度历史的温度历史成像装置，而不在测量之前消耗电能。

63. 发明授权

US6074360A Electromagnetic transdermal injection device and methods related thereto 失效
标题翻译：电磁透皮注射装置及其相关方法
公开(公告)号：US6074360A
公开(公告)日：2000-06-13
申请号：US897433
申请日：1997-07-21
申请人： Hans-Peter Haar , George B. Kirby Meacham , Manfred Beuttenmueller , Gerhard Winter , Markus Mattern
发明人： Hans-Peter Haar , George B. Kirby Meacham , Manfred Beuttenmueller , Gerhard Winter , Markus Mattern
IPC分类号： F41B6/00 , A61M5/30 , A61M31/00
CPC分类号： F41B6/003 , A61M5/30
摘要： Featured is a method for injection of a payload into the tissues of an organism or a body, including the steps of generating forces by electromagnetic repulsion and accelerating the payload to be injected, using the generated electromagnetic forces. The payload is thereby accelerated to a velocity sufficient for the payload to pass through the skin of the organism and be disposed in the subcutaneous tissues. The method further includes providing an electromagnetic force generating device that generates forces electromagnetically in a predetermined direction responsive to an electric current flowing through the device, wherein the step of generating includes passing an electric current through the electromagnetic force generating device to generate the electromagnetic repulsive forces used for accelerating the payload. Also featured is a electromagnetic force generating mechanism that includes a conductive member, which is configured so as to generate electromagnetic repulsive forces in a given direction to accelerate the payload responsive to a pulsed current passing through the conductive member. Additionally featured is an electromagnetic transdermal injection device including such an electromagnetic force generating mechanism, an electrical power supply and a switch that selectively interconnects the power supply and force generating mechanism to accelerate a payload such as a medicine.
摘要翻译：特征是将有效载荷注入生物或身体的组织的方法，包括通过电磁排斥产生力并使用产生的电磁力加速待注射的有效载荷的步骤。因此有效载荷被加速到足以使有效载荷穿过生物体的皮肤并且被布置在皮下组织中的速度。该方法还包括提供电磁力产生装置，其响应于流过该装置的电流而在预定方向上以电磁方式产生力，其中产生步骤包括使电流通过电磁力产生装置以产生电磁排斥力用于加速有效载荷。电磁力产生机构还包括导电构件，其被构造成在给定方向上产生电磁排斥力，以响应于穿过导电构件的脉冲电流来加速有效载荷。另外特征在于包括这种电磁力产生机构的电磁透皮注射装置，电源和开关，其选择性地互连电源和力产生机构以加速诸如药物的有效载荷。

64. 发明授权

US5977545A Sample carrier for use in infrared transmission spectroscopy 失效
标题翻译：用于红外线透射光谱的样品载体
公开(公告)号：US5977545A
公开(公告)日：1999-11-02
申请号：US952823
申请日：1997-12-03
申请人： Hans-Peter Haar , Gerhard Werner
发明人： Hans-Peter Haar , Gerhard Werner
IPC分类号： G01N21/01 , G01N21/03 , G01N21/35 , G01N21/00
CPC分类号： G01N21/03
摘要： A sample carrier and a method for performing quantitative IR transmission spectroscopy utilizes infrared radiation of a suitable wavelength for measuring a sample. The sample carrier includes a sample platform and a holder for holding the sample platform. A thickness of the sample platform is less than one quarter of a shortest wavelength of the suitable wavelength range. The sample platform is transparent to the infrared radiation in the suitable wavelength range.
摘要翻译： PCT No.PCT / EP96 / 02321 Sec。 371日期1997年12月3日第 102（e）1997年12月3日日期PCT提交1996年5月30日PCT公布。出版物WO96 / 39620 PCT 日期1996年12月12日一种样品载体和用于进行定量IR透射光谱的方法利用适合波长的红外辐射来测量样品。样品载体包括样品平台和用于保持样品平台的保持器。样品平台的厚度小于合适波长范围的最短波长的四分之一。样品平台对于适当波长范围内的红外辐射是透明的。

65. 发明授权

US5893364A Apparatus for light reflection measurements 失效
标题翻译：光反射测量装置
公开(公告)号：US5893364A
公开(公告)日：1999-04-13
申请号：US752629
申请日：1996-11-19
申请人： Hans-Peter Haar , Matthias Essenpreis , Rainer Fritsche
发明人： Hans-Peter Haar , Matthias Essenpreis , Rainer Fritsche
IPC分类号： G01N33/483 , A61B5/00 , A61B5/145 , A61B5/1455 , G01N21/47 , G01N33/50
CPC分类号： G01N21/474 , A61B5/0059 , A61B5/14552
摘要： An apparatus for light transport measurements on a test object with a measuring head which includes a contact surface for placing against an interface of the test object, light irradiation device with a light transmitter for irradiating light through the contact surface and an interface into the test object, and detection device with a light receiver for detecting light leaving the test object. The contact surface comprises at least one optically transparent light passage point for the light, on which a large number of rigid light-conducting elements are arranged, wherein an optical connection with a light transmitter or light receiver assigned to a light passage point is produced by the whole of the light-conducting elements of the light passage site.
摘要翻译：一种用于在具有测量头的测试对象上进行光传输测量的装置，其包括用于放置在测试对象的界面上的接触表面，具有用于通过接触表面照射光的光发射器的光照射装置和到测试对象的界面以及具有用于检测离开测试对象的光的光接收器的检测装置。接触表面包括用于光的至少一个光学透明光通过点，其上布置有大量刚性导光元件，其中与分配给光通过点的光发射器或光接收器的光学连接通过光通道位置的整个导光元件。

66. 发明授权

US5770454A Method and aparatus for determining an analyte in a biological sample 失效
标题翻译：用于测定生物样品中分析物的方法和装置
公开(公告)号：US5770454A
公开(公告)日：1998-06-23
申请号：US737135
申请日：1996-11-07
申请人： Matthias Essenpreis , Dirk Boecker , Heinz-Michael Hein , Hans-Peter Haar
发明人： Matthias Essenpreis , Dirk Boecker , Heinz-Michael Hein , Hans-Peter Haar
IPC分类号： A61B5/00 , G01N21/49 , G01N21/00
CPC分类号： A61B5/1455 , A61B5/14532 , G01N21/49 , A61B2562/0233 , A61B2562/0242 , A61B2562/043
摘要： A method and apparatus for analytical determination of a concentration of an analyte in a biological sample include a series of hardware elements and method steps which perform at least two detection measurements, with each detection measurement including the step of irradiating light at an irradiation site as primary light into the biological sample through a boundary surface. The light is propagated along a light path, and light is detected as it emerges from the biological sample as secondary light through a detection site. The irradiation site and detection site are separated by a measuring distance. At least two detection measurements are performed with at least two different measurement light paths between the irradiation site and the detection site. Each of the detection measurements is a frequency-domain spectroscopic measurement which is performed at at least two different wavelengths of light, and includes a comparison of a phase shift of the secondary light with the primary light as a first measurement variable, and an intensity of the secondary light as a second measurement variable. The method also includes the steps of determining the analyte concentration based upon the first and second measurement variables.
摘要翻译： PCT No.PCT / DE95 / 00593 Sec。 371日期：1996年11月7日 102（e）日期1996年11月7日PCT提交1995年5月3日PCT公布。公开号WO95 / 32416 PCT 日期：1995年11月30日用于分析生物样品中分析物浓度的方法和装置包括执行至少两次检测测量的一系列硬件元件和方法步骤，每个检测测量包括将光照射到照射部位作为通过边界表面进入生物样品的初级光。光沿光路传播，当从生物样品出现时，通过检测部位作为二次光检测出光。照射部位和检测部位通过测量距离分开。在照射部位和检测部位之间至少有两个不同的测量光路进行至少两次检测测量。每个检测测量是在至少两个不同波长的光下执行的频域光谱测量，并且包括将次级光与初级光的相移作为第一测量变量的比较，以及次光作为第二测量变量。该方法还包括基于第一和第二测量变量确定分析物浓度的步骤。

67. 发明授权

US5413764A Test carrier analysis system 失效
标题翻译：测试载体分析系统
公开(公告)号：US5413764A
公开(公告)日：1995-05-09
申请号：US503585
申请日：1990-04-03
申请人： Hans-Peter Haar
发明人： Hans-Peter Haar
IPC分类号： G01N21/78 , G01N21/86 , G01N33/52 , G01N21/75
CPC分类号： G01N21/8483 , G01N33/521
摘要： A test carrier analysis system for analyzing a body fluid, the system including a test carrier (1) with a detection layer (20) on which a detectable change specific to the analysis takes place, obeying an evaluation curve, to the concentration of the component, and wherein the evaluation curve is dependent on the manufacturing batch of the test carrier. The system further includes an evaluator having a measuring and digitization circuit (25) which generates from the physically detectable change an intermediate result independent of the evaluation curve in the form of a finite number of digital output states, and having a display (7) for indicating the output states in the form of an alpha and/or numeric code. A readable information carrier element is provided having a correlation thereon between the alphanumeric codes of the display (7) corresponding to the output states and the concentration values determined in accordance with the evaluation curve.
摘要翻译：一种用于分析体液的测试载体分析系统，所述系统包括具有检测层（20）的测试载体（1），在所述测试载体（1）上发生对所述分析特异性的可检测变化，服从评估曲线，，并且其中评估曲线取决于测试载体的制造批次。该系统还包括具有测量和数字化电路（25）的评估器，其从物理上可检测的变化产生独立于有限数量的数字输出状态形式的评估曲线的中间结果，并且具有显示器（7），用于以alpha和/或数字代码的形式指示输出状态。提供了一种可读信息载体元件，其在与输出状态相对应的显示器（7）的字母数字代码与根据评估曲线确定的浓度值之间具有相关性。

68. 发明授权

US4456581A Centrifugal analyzer rotor unit and insert elements 失效
标题翻译：离心分析仪转子单元和插入元件
公开(公告)号：US4456581A
公开(公告)日：1984-06-26
申请号：US323343
申请日：1981-11-20
申请人： Hermann Edelmann , Manfred Pasch , Sigmar Klose , Hans-Peter Haar , Karlheinz Mann
发明人： Hermann Edelmann , Manfred Pasch , Sigmar Klose , Hans-Peter Haar , Karlheinz Mann
IPC分类号： G01N33/48 , B01F5/06 , B01F13/00 , B04B5/04 , G01N21/07 , G01N35/00 , G01N37/00
CPC分类号： B01L3/5027 , B01F15/0233 , B01F5/0641 , B01F5/0682 , B01F5/0694 , B04B5/0407 , G01N21/07 , B01F13/0059 , B01L2200/028 , B01L2200/16 , B01L2300/021 , B01L2300/0806 , B01L2400/0409
摘要： A rotor unit for a centrifugal analyzer comprises a rotatably driven circular rotor base; and a rotor head comprising a plurality of insert elements each having at least one chamber sample for the reception of a sample liquid, at least one measuring chamber radially outwardly from the associated sample chamber for the measurement of characteristic parameters for the detection of components of the sample, at least one liquid channel connecting the sample chamber with the measuring chamber and each insert element is releasably mounted on the rotor base at any one of a plurality of different selectable angular positions wherein the insert element is positionally stable when the rotor base is rotating.
摘要翻译：用于离心分析器的转子单元包括可旋转地驱动的圆形转子基座; 以及转子头，其包括多个插入元件，每个插入元件具有至少一个用于接收样品液体的室样品，至少一个从相关联的样品室径向向外的测量室，用于测量用于检测样品的组分的特征参数样品，将样品室与测量室连接的至少一个液体通道和每个插入元件可以以多个不同的可选角度位置中的任何一个可释放地安装在转子基座上，其中当转子基座旋转时，插入元件位置稳定。

69. 发明授权

US09282922B2 Medical system comprising a compact barcode reader for consumable items 有权
标题翻译：医疗系统包括用于消耗品的紧凑型条形码读取器
公开(公告)号：US09282922B2
公开(公告)日：2016-03-15
申请号：US13021382
申请日：2011-02-04
申请人： Hans-Peter Haar , Gerrit Kocherscheidt
发明人： Hans-Peter Haar , Gerrit Kocherscheidt
IPC分类号： A61B5/145 , A61B19/00 , A61B5/1455
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/1455 , A61B90/90 , A61B90/94 , A61B90/96 , A61B90/98 , A61B2562/0295 , A61B2562/08
摘要： A medical system is proposed comprising at least one medical device for carrying out at least one medical function, and at least one medical consumable item interacting with the medical device in order to carry out the medical function. The medical device has at least one code reader for reading out at least one information component of an optical code on the medical consumable item. The code reader has at least one image sensor having a plurality of sensors. Furthermore, the code reader comprises at least one light-optical fiber plate, which is arranged in order to guide an image of the optical code to the image sensor.
摘要翻译：提出了一种医疗系统，其包括用于执行至少一个医疗功能的至少一个医疗装置，以及与医疗装置相互作用以执行医疗功能的至少一个医疗消耗品。该医疗设备具有至少一个代码读取器，用于读取医疗用消耗品上的光学代码的至少一个信息分量。代码阅读器具有至少一个具有多个传感器的图像传感器。此外，代码阅读器包括至少一个光 - 光纤板，其布置成将光学代码的图像引导到图像传感器。

70. 发明授权

US08821442B2 Infusion system 有权
标题翻译：输液系统
公开(公告)号：US08821442B2
公开(公告)日：2014-09-02
申请号：US12542047
申请日：2009-08-17
申请人： Hans-Peter Haar
发明人： Hans-Peter Haar
IPC分类号： A61M1/00 , A61M5/142 , H02J7/00 , A61M5/168 , A61B5/145 , A61M5/145
CPC分类号： A61M5/14248 , A61B5/14532 , A61M5/14566 , A61M5/16854 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/8206 , A61M2209/045 , A61M2209/086
摘要： Disclosed is an infusion system for administering a liquid medicament, particularly insulin. Said infusion system comprises a cannula support unit which is properly attached to a patient's body, an infusion cannula to be inserted into the patient's body, and a pump unit that can be connected to the cannula support unit and encompasses a pump, a battery for supplying power to the pump, and a storage volume for the medicament that is to be administered. The pump unit and the cannula support unit are adapted to one another in such a way that the pump unit rests against the cannula support unit once the pump unit has been connected to the cannula support unit. The disclosed infusion system also comprises a charging station for the pump unit in order to recharge the battery of the pump unit.
摘要翻译：公开了一种用于施用液体药物，特别是胰岛素的输注系统。所述输注系统包括适当地附接到患者身体的插管支撑单元，插入到患者体内的输液套管以及能够连接到套管支撑单元并包围泵，用于供应的电池的泵单元泵的功率以及待施用的药物的储存体积。泵单元和插管支撑单元彼此适配，使得一旦泵单元已经连接到插管支撑单元，泵单元就靠在套管支撑单元上。所公开的输注系统还包括用于泵单元的充电站，以便为泵单元的电池再充电。

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