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61. 发明授权

US5758644A Manual and automatic probe calibration 失效
公开(公告)号：US5758644A
公开(公告)日：1998-06-02
申请号：US478493
申请日：1995-06-07
申请人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
发明人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/1495 , G01J3/10 , G01J3/28 , G01N21/01 , G01N21/25 , G01N21/27 , G01N21/39 , G01N21/64 , G05F3/08 , H05B37/02
CPC分类号： A61B5/1495 , A61B5/0205 , A61B5/14552 , A61B5/6826 , A61B5/6838 , G01J3/02 , G01J3/0254 , G01J3/027 , G01J3/0275 , G01J3/0291 , G01J3/10 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/39 , A61B2562/08 , A61B5/02427 , G01J2003/2866 , G01N2021/3144 , G01N2201/0627
摘要： The method and apparatus of the present invention provides a system wherein light-emitting diodes (LEDs) can be tuned within a given range by selecting their operating drive current in order to obtain a precise wavelength. The present invention further provides a manner in which to calibrate and utilize an LED probe, such that the shift in wavelength for a known change in drive current is a known quantity. In general, the principle of wavelength shift for current drive changes for LEDs is utilized in order to allow better calibration and added flexibility in the use of LED sensors, particularly in applications when the precise wavelength is needed in order to obtain accurate measurements. The present invention also provides a system in which it is not necessary to know precise wavelengths of LEDs where precise wavelengths were needed in the past. Finally, the present invention provides a method and apparatus for determining the operating wavelength of a light emitting element such as a light emitting diode.

62. 发明授权

US08781543B2 Manual and automatic probe calibration 失效
标题翻译：手动和自动探头校准
公开(公告)号：US08781543B2
公开(公告)日：2014-07-15
申请号：US13430451
申请日：2012-03-26
申请人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
发明人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
IPC分类号： A61B5/1455
CPC分类号： A61B5/1495 , A61B5/0205 , A61B5/02427 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B2562/08 , G01J3/02 , G01J3/0254 , G01J3/027 , G01J3/0275 , G01J3/0291 , G01J3/10 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/39 , G01N2021/3144 , G01N2201/0627
摘要： Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like.
摘要翻译：本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等。该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。

63. 发明授权

US08457707B2 Congenital heart disease monitor 有权
标题翻译：先天性心脏病监测
公开(公告)号：US08457707B2
公开(公告)日：2013-06-04
申请号：US11858053
申请日：2007-09-19
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/0205 , A61B5/02055 , A61B5/02416 , A61B5/14551 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/7275 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2560/0276 , G06F19/00
摘要： A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response. The physiological parameter is measured at a baseline site and a comparison site and a difference in these measurements is calculated. A potential congenital heart disease condition in indicated according to the measured physiological parameter at each of the sites or the calculated difference in the measured physiological parameter between the sites or both.
摘要翻译：先天性心脏病监测器使用能够将多个波长的光辐射发射到组织部位的传感器，并且通过在组织部位内流动的脉动血液来检测衰减后的光辐射。患者监护仪能够接收对应于检测到的光辐射的传感器信号，并且响应地计算至少一个生理参数。在基线位置和比较位置测量生理参数，并计算这些测量值的差异。根据每个部位的测量生理参数指示的潜在先天性心脏病状况或两个部位之间测量的生理参数的计算差异。

64. 发明申请

US20110208018A1 SEPSIS MONITOR 有权
公开(公告)号：US20110208018A1
公开(公告)日：2011-08-25
申请号：US13100172
申请日：2011-05-03
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61B5/08 , A61B5/1455
CPC分类号： A61M5/1723 , A61B5/0205 , A61B5/022 , A61B5/02455 , A61B5/08 , A61B5/082 , A61B5/14551 , A61B5/412 , A61B5/6826 , A61B5/6838 , A61B7/04 , A61B2560/0276
摘要： Sensors are attached to a living being so as to generate corresponding sensor signals. A monitor is in communications with the sensors so as to derive physiological parameters responsive to the sensor signals. Predetermined limits are applied to the physiological parameters. At least one indicator responsive to the physiological parameters and the predetermined limits signal the onset of a sepsis condition in the living being.
摘要翻译：传感器连接在一起，以产生相应的传感器信号。监视器与传感器通信，以响应于传感器信号而导出生理参数。将预定极限应用于生理参数。响应于生理参数和预定限度的至少一个指示符表示生活中脓毒症状况的发作。

65. 发明授权

US07941199B2 Sepsis monitor 有权
标题翻译：脓毒症监测
公开(公告)号：US07941199B2
公开(公告)日：2011-05-10
申请号：US11803936
申请日：2007-05-15
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61M5/1723 , A61B5/0205 , A61B5/022 , A61B5/02455 , A61B5/08 , A61B5/082 , A61B5/14551 , A61B5/412 , A61B5/6826 , A61B5/6838 , A61B7/04 , A61B2560/0276
摘要： Sensors are attached to a living being so as to generate corresponding sensor signals. A monitor is in communications with the sensors so as to derive physiological parameters responsive to the sensor signals. Predetermined limits are applied to the physiological parameters. At least one indicator responsive to the physiological parameters and the predetermined limits signal the onset of a sepsis condition in the living being.
摘要翻译：传感器连接在一起，以产生相应的传感器信号。监视器与传感器通信，以响应于传感器信号而导出生理参数。将预定极限应用于生理参数。响应于生理参数和预定限度的至少一个指示符表示生活中脓毒症状况的发作。

66. 发明授权

US07844313B2 Pulse oximetry sensor adapter 有权
标题翻译：脉搏血氧饱和度传感器适配器
公开(公告)号：US07844313B2
公开(公告)日：2010-11-30
申请号：US11341999
申请日：2006-01-27
申请人： Massi E. Kiani , Robert A. Smith , David R. Tobler
发明人： Massi E. Kiani , Robert A. Smith , David R. Tobler
IPC分类号： A61B5/00 , A61B5/1455
CPC分类号： A61B5/14551 , A61B5/14552 , A61B2562/222 , G06F19/00 , Y10S439/909
摘要： An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.
摘要翻译：适配器允许来自一个制造商的传感器的互连与来自其他制造商的常规不兼容的监视器耦合以形成正常工作的脉搏血氧饱和度系统。适配器将监视器中的传感器驱动器与传感器的当前要求和光源配置相匹配。适配器还将传感器的光检测器信号电平与监视器前置放大器的动态范围要求相匹配。此外，适配器向监视器提供兼容的传感器校准，传感器类型和安全信息。适配器可以具有独立的电源，或者可以从监视器获得电力，从而允许被动和主动适配器组件。适配器特别适合作为适配器电缆，替代传统的患者电缆或传感器电缆作为脉搏血氧测定系统中的传感器与监视器之间的互连。

67. 发明授权

US07526328B2 Manual and automatic probe calibration 失效
标题翻译：手动和自动探头校准
公开(公告)号：US07526328B2
公开(公告)日：2009-04-28
申请号：US11640077
申请日：2006-12-15
申请人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
发明人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
IPC分类号： A61B5/1455
CPC分类号： A61B5/1495 , A61B5/0205 , A61B5/02427 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B2562/08 , G01J3/02 , G01J3/0254 , G01J3/027 , G01J3/0275 , G01J3/0291 , G01J3/10 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/39 , G01N2021/3144 , G01N2201/0627
摘要： Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like. In one preferred embodiment, coding resistors could be provided across the light sources to allow additional information about the probe to be coded without added leads. However, any device could be used without it being used in parallel.
摘要翻译：本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等。该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。在一个优选实施例中，编码电阻器可以跨越光源提供，以允许关于探针的附加信息被编码而没有添加引线。但是，任何设备都可以在没有并行使用的情况下使用。

68. 发明授权

US06993371B2 Pulse oximetry sensor adaptor 有权
标题翻译：脉搏血氧饱和度传感器适配器
公开(公告)号：US06993371B2
公开(公告)日：2006-01-31
申请号：US10624446
申请日：2003-07-22
申请人： Massi E. Kiani , Robert A. Smith , David R. Tobler
发明人： Massi E. Kiani , Robert A. Smith , David R. Tobler
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/14552 , A61B2562/222 , G06F19/00 , Y10S439/909
摘要： An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.
摘要翻译：适配器允许来自一个制造商的传感器的互连与来自其他制造商的常规不兼容的监视器耦合以形成正常工作的脉搏血氧饱和度系统。适配器将监视器中的传感器驱动器与传感器的当前要求和光源配置相匹配。适配器还将传感器的光检测器信号电平与监视器前置放大器的动态范围要求相匹配。此外，适配器向监视器提供兼容的传感器校准，传感器类型和安全信息。适配器可以具有独立的电源，或者可以从监视器获得电力，从而允许被动和主动适配器组件。适配器特别适合作为适配器电缆，替代传统的患者电缆或传感器电缆作为脉搏血氧测定系统中的传感器与监视器之间的互连。

69. 再颁专利

USRE38492E1 Signal processing apparatus and method 失效
标题翻译：信号处理装置及方法
公开(公告)号：USRE38492E1
公开(公告)日：2004-04-06
申请号：US10095586
申请日：2002-03-11
申请人： Mohamed Kheir Diab , Massi E. Kiani
发明人： Mohamed Kheir Diab , Massi E. Kiani
IPC分类号： A61B500
CPC分类号： G06K9/0051 , A61B5/14551 , A61B5/7214 , A61B5/7228 , H04B1/123
摘要： A signal processor which acquires a first signal, including a first desired signal portion and a first undesired signal portion, and a second signal, including a second desired signal portion and a second undesired signal portion, wherein the first and second desired signal portions are correlated. The signals may be acquired by propagating energy through a medium and measuring an attenuated signal after transmission or reflection. Alternatively, the signals may be acquired by measuring energy generated by the medium. A processor generates a noise reference signal which is a combination of only the undesired signal portions and is correlated to both the first and second undesired signal portions. The noise reference signal is then used to remove the undesired portion of each of the first and second measured signals via an adaptive noise canceler, preferably of the joint process estimator type. The processor may be employed in conjunction with an adaptive noise canceler in physiological monitors wherein the know properties of energy attenuation through a medium are used to determine physiological characteristics of the medium. Many physiological conditions, such as the pulse of a patient or the concentration of a constituent in a medium, can be determined from the desired portion of the signal after undesired signal portions, such as those caused by erratic motion, are removed.

70. 发明授权

US06526300B1 Pulse oximeter probe-off detection system 有权
标题翻译：脉搏血氧仪探头检测系统
公开(公告)号：US06526300B1
公开(公告)日：2003-02-25
申请号：US09595081
申请日：2000-06-16
申请人： Massi E. Kiani , Mohamed K. Diab
发明人： Massi E. Kiani , Mohamed K. Diab
IPC分类号： A61B500
CPC分类号： A61B5/6843 , A61B5/14552
摘要： The present invention provides a number of improvements that can be incorporated into a pulse oximeter probe to detect when a probe has become dislodged from a patient and/or to prevent a probe-off condition. A probe-off condition occurs when the optical probe becomes partially or completely dislodged from the patient, but continues to detect an AC signal within the operating region of the pulse oximeter. In one aspect, the present invention provides electrical contacts that contact the skin of a patient when the probe is properly attached. In another aspect, the present invention provides a number of louvers placed in front of the sensor's photodetector to filter out oblique light rays that do not originate from a point in front of the detector. Accordingly, if the emitter and photodetector are not properly aligned, the photodetector will not produce a signal within the valid operating range of the pulse oximeter. In accordance with a method of the present invention the pulse oximeter can sound an alarm or display a warning if it determines that the probe is not properly attached to the patient.
摘要翻译：本发明提供了许多可以结合到脉搏血氧计探针中以检测探针什么时候已经从患者脱离和/或防止探针状态的改进。当光学探针从患者部分或完全脱落而继续检测到在脉搏血氧计的操作区域内的AC信号时，会发生探测条件。一方面，本发明提供了当探针适当地附接时与患者的皮肤接触的电触点。在另一方面，本发明提供了放置在传感器的光电检测器前方的多个百叶窗，以过滤出不是源于检测器前面的点的倾斜光线。因此，如果发射器和光电检测器未正确对准，则光电检测器将不会在脉冲血氧计的有效工作范围内产生信号。根据本发明的方法，如果脉搏血氧计确定探头未正确地附接到患者，则脉搏血氧计可以发出警报或显示警告。

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