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61. 发明申请

US20060015392A1 Method and apparatus for ranking users according to evaluating providers of information 审中-公开
标题翻译：根据评估信息提供者对用户进行排名的方法和装置
公开(公告)号：US20060015392A1
公开(公告)日：2006-01-19
申请号：US10892349
申请日：2004-07-16
申请人： Surendranath Talla , Andrew Robinson
发明人： Surendranath Talla , Andrew Robinson
IPC分类号： G06F17/60
CPC分类号： G06Q30/02 , G06Q10/0639
摘要： A method and system for evaluating providers of information. The method comprises of the steps of allotting endorsement value points to such providers, allowing providers to transfer some or all of their endorsement value points to one or more other providers to enable that other provider or providers to increase their value as a provider. The system provides apparatus to run the method.
摘要翻译：一种评估信息提供者的方法和系统。该方法包括以下步骤：向这些提供者分配认可价值点，允许提供者将其部分或全部的认可价值点转移给一个或多个其他供应商，以使其他供应商或供应商能够提高其作为提供者的价值。该系统提供运行该方法的装置。

62. 发明授权

US06612987B2 Apparatus and method for selectively optimizing an acoustic transducer 失效
标题翻译：用于选择性地优化声换能器的装置和方法
公开(公告)号：US06612987B2
公开(公告)日：2003-09-02
申请号：US10011160
申请日：2001-12-05
申请人： Ahmed Morsy , Andrew Robinson
发明人： Ahmed Morsy , Andrew Robinson
IPC分类号： A61B800
CPC分类号： G01S7/5205 , A61B8/00 , G01S7/5208 , G01S15/8979
摘要： The invention is directed towards an apparatus and method for selectively optimizing piezoelectric elements in an ultrasound transducer assembly for a given imaging mode. In one embodiment, a variable impedance network is interposed between an ultrasound processor and a transducer assembly and may be coupled to the transducer assembly to form either a series or a parallel connection with the transducer assembly. The network may be controlled by the processor to selectively alter the characteristics of the network. In another embodiment, the variable impedance network includes a pair of serially coupled inductors and a switch that permits one of the inductors to be controllably bypassed. In still another embodiment, the network includes a tapped inductor and a switch to permit the inductor tap to be controllably selected. In still another aspect, the inductor includes a tapped inductor having multiple taps, each tap selectable by a switch to optimize the network.
摘要翻译：本发明涉及用于选择性地优化用于给定成像模式的超声换能器组件中的压电元件的装置和方法。在一个实施例中，可变阻抗网络介于超声处理器和换能器组件之间，并且可耦合到换能器组件以与换能器组件形成串联或并联连接。网络可以由处理器控制以选择性地改变网络的特性。在另一个实施例中，可变阻抗网络包括一对串联耦合的电感器和允许电感器之一被可控地绕过的开关。在另一个实施例中，网络包括抽头电感器和允许可控制地选择电感器抽头的开关。在另一方面，电感器包括具有多个抽头的抽头电感器，每个抽头可由开关选择以优化网络。

63. 发明授权

US06597495B2 Four wave mixing reduction in raman amplifiers 有权
公开(公告)号：US06597495B2
公开(公告)日：2003-07-22
申请号：US09982329
申请日：2001-10-18
申请人： Marina Gertsvolf , Andrew Robinson , Baozhu Steven Luo , Robert Larose , James Ghadbane
发明人： Marina Gertsvolf , Andrew Robinson , Baozhu Steven Luo , Robert Larose , James Ghadbane
IPC分类号： H04B1012
CPC分类号： H04B10/2916 , H01S3/094046 , H01S3/094076 , H01S3/302 , H01S2301/02 , H01S2301/06 , H04B10/2563
摘要： An improved method is provided for reducing four-wave mixing induced degradation in an optical data signal traversing an optical transport network that uses Raman amplifiers. The method includes: introducing at least two Raman amplifiers into the optical transport network, each Raman amplifier having a laser source, and synchronously modulating the laser sources of the Raman amplifiers, thereby reducing four-wave mixing in the optical data signal. Modulation of the laser sources is performed at such a rate that crosstalk from the modulation to the optical data signals experiencing the Raman gain is minimized.

64. 发明授权

US4784589A Purification of pertussis antigens 失效
标题翻译：百日咳抗原的纯化
公开(公告)号：US4784589A
公开(公告)日：1988-11-15
申请号：US8880
申请日：1987-01-20
申请人： Andrew Robinson , Laurence I. Irons
发明人： Andrew Robinson , Laurence I. Irons
IPC分类号： C07K14/195 , A61K39/00 , A61K39/095 , A61K39/10 , A61P31/04 , C07K1/36 , C07K14/005 , C07K14/235 , C07K14/41 , C07K14/52 , C12P21/00 , C12R1/01 , C07K3/12 , C07K3/28
CPC分类号： C07K14/235 , A61K39/00 , Y10S530/825
摘要： A process is provided for the production of lymphocytosis promoting factor (LPF), filamentous haemagglutinin (FHA) and at least one fimbrial agglutinogen from a liquid culture of Bordetella pertussis, which comprises the steps of (a) separating the culture into cellular and supernatant fractions, (b) concentrating the supernatant fraction, (c) fractionating the concentrated supernatant fraction to isolate LPF and FHA containing fractions, and (d) isolating at least one fimbrial agglutinogen from the cellular fraction. A vaccine composition may be produced by mixing so-produced LPF, FHA and fimbrial agglutinogens produced.
摘要翻译：提供了用于从百日咳杆菌属液体培养物中产生淋巴细胞增多促进因子（LPF），丝状血凝素（FHA）和至少一种菌毛凝集素的方法，其包括以下步骤：（a）将培养物分离成细胞和上清液级分（b）浓缩上清液部分，（c）分离浓缩的上清液部分以分离含有LPF和FHA的级分，和（d）从细胞级分中分离至少一种菌毛凝集素。疫苗组合物可以通过混合所生产的LPF，FHA和冷冻凝集素来生产。

65. 发明授权

US4248862A Immunogenic cell envelope preparations 失效
标题翻译：免疫原细胞包膜制剂
公开(公告)号：US4248862A
公开(公告)日：1981-02-03
申请号：US12857
申请日：1979-02-16
申请人： Derek C. Ellwood , Richard J. Manchee , Andrew Robinson
发明人： Derek C. Ellwood , Richard J. Manchee , Andrew Robinson
IPC分类号： A61K39/10
CPC分类号： A61K39/099
摘要： An antigenically-active cell envelope fraction from bacterial cells, especially Bordetella pertussis, may be isolated by disrupting the cells, separating the cell envelopes from the other cell components, extracting the separated envelopes with a solution of a zwitterionic surfactant and precipitating the cell envelope preparation from the resulting extract by the addition of a lower alkyl (C.sub.1 to C.sub.5) alcohol, preferably ethanol. The preferred extractant is an N, N, N-trialkyl zwitterionic compound especially an N, N, N-trialkyl-.alpha.-amino acid or an N, N, N-trialkyl amine oxide.The cell envelope fraction obtained from B. pertussis is highly protective against whole bacteria when tested by standard vaccine mouse potency assay and has a greatly reduced lipopolysaccharide content compared with either whole cells or crude cell envelopes, greatly reducing the risk of undesirable side-effects from vaccination.
摘要翻译：来自细菌细胞，特别是百日咳博德特氏菌的抗原活性细胞包膜部分可以通过破坏细胞，将细胞包膜与其他细胞成分分离，用两性离子表面活性剂溶液萃取分离的包膜并沉淀细胞包膜制剂通过加入低级烷基（C1至C5）醇，优选乙醇从所得提取物中提取。优选的萃取剂是N，N，N-三烷基两性离子化合物，特别是N，N，N-三烷基-α-氨基酸或N，N，N-三烷基氧化胺。从百日咳酵母获得的细胞包膜分数在通过标准疫苗小鼠效力测定法测试时对整个细菌具有高度保护性，与全细胞或粗细胞包膜相比，脂多糖含量大大降低，从而大大降低了不利副作用的风险接种疫苗

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