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61. 发明授权

US09018391B2 Inhibitors of beta-secretase 有权
标题翻译： β-分泌酶抑制剂
公开(公告)号：US09018391B2
公开(公告)日：2015-04-28
申请号：US14011183
申请日：2013-08-27
申请人： Yuri Bukhtiyarov , Salvacion Cacatian , Lawrence Wayne Dillard , Klaus Fuchs , Lanqi Jia , Deepak S. Lala , Angel Morales-Ramos , Suresh B. Singh , Shankar Venkatraman , Zhenrong Xu , Jing Yuan , Yi Zhao , Yajun Zheng , Cornelia Dorner-Ciossek , Ulrike Gross , Niklas Heine , Achim Sauer
发明人： Yuri Bukhtiyarov , Salvacion Cacatian , Lawrence Wayne Dillard , Klaus Fuchs , Lanqi Jia , Deepak S. Lala , Angel Morales-Ramos , Suresh B. Singh , Shankar Venkatraman , Zhenrong Xu , Jing Yuan , Yi Zhao , Yajun Zheng , Cornelia Dorner-Ciossek , Ulrike Gross , Niklas Heine , Achim Sauer
IPC分类号： C07D235/02 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/14 , C07D405/06 , C07D401/14 , A61K31/4184
CPC分类号： C07D235/02 , A61K31/4184 , A61K31/4439 , A61K31/506 , C07C49/747 , C07C49/755 , C07C229/50 , C07C255/59 , C07C313/06 , C07C331/26 , C07C2603/94 , C07C2603/97 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D405/06
摘要： The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.
摘要翻译：本发明涉及螺环酰基胍及其作为分泌酶（BACE1）活性的抑制剂，含有它们的药物组合物的用途，以及将其用作治疗神经变性疾病的治疗剂的方法，其特征在于认知衰退，认知障碍，痴呆和以淀粉样蛋白聚集体生产为特征的疾病。

62. 发明授权

US08920790B2 Uses of IL-12 in hematopoiesis 有权
标题翻译：在造血中使用IL-12
公开(公告)号：US08920790B2
公开(公告)日：2014-12-30
申请号：US13076365
申请日：2011-03-30
申请人： Tingchao Chen , Yi Zhao , W. French Anderson
发明人： Tingchao Chen , Yi Zhao , W. French Anderson
IPC分类号： A61K38/20 , A61P35/02 , A61P35/00 , C07K14/54 , A61K45/06 , A61N5/10
CPC分类号： A61K38/208 , A61K31/675 , A61K38/193 , A61K45/06 , A61N5/10 , A61N2005/1098 , C07K14/53 , C07K14/5434 , A61K2300/00
摘要： Methods for enhancing or stimulating hematopoiesis including the step of administering Interleukin-12 (IL-12) to yield hematopoietic recovery in a mammal in need. Preferred methods include the step of administering IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other methods include administering IL-12 to ameliorate various hematopoietic deficiencies. Still other methods are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed methods are directed to uses of IL-12 for bone marrow preservation or recovery.
摘要翻译：用于增强或刺激造血的方法，包括施用白细胞介素-12（IL-12）以在需要的哺乳动物中产生造血回收的步骤。优选的方法包括施用IL-12作为辅助治疗以减轻与用于对抗疾病状态的一种或多种治疗方案相关的造血毒性的步骤。其他方法包括给予IL-12以改善各种造血缺陷。还有其它方法涉及IL-12用于造血再生细胞，造血祖细胞和造血干细胞的体内增殖的用途。其他公开的方法涉及IL-12用于骨髓保存或恢复的用途。

63. 发明授权

US08805355B2 Method for reducing failure of configuration update initiated by eNB and eNB 有权
标题翻译：减少由eNB和eNB发起的配置更新失败的方法
公开(公告)号：US08805355B2
公开(公告)日：2014-08-12
申请号：US13576824
申请日：2010-11-23
申请人： Yi Zhao
发明人： Yi Zhao
IPC分类号： H04W24/00 , H04L12/24 , H04W24/04 , H04W88/08
CPC分类号： H04L41/082 , H04L41/0681 , H04W24/04 , H04W88/08
摘要： The present invention provides a method for reducing failure of configuration update initiated by an evolved Node B (eNB) and the eNB thereof. The method includes: after the configuration is updated, the eNB compares Public Land Mobile telephone Network (PLMN) information of the local end with the PLMN information of a Mobility Management Entity (MME) stored in the local end (101); when the PLMN information of the local end is completely consistent with the PLMN information of the MME stored by the local end, the eNB sends a configuration update request to the MME (102); or, when they are partially consistent, the eNB sends a configuration update request to the MME and alarms (103); or, when the PLMN information of the local end is completely inconsistent with the PLMN information of the MME stored in the local end, the eNB alarms (104).
摘要翻译：本发明提供了一种减少由演进节点B（eNB）及其eNB发起的配置更新失败的方法。该方法包括：在更新配置之后，eNB将本地的公共陆地移动电话网（PLMN）信息与存储在本端（101）中的移动性管理实体（MME）的PLMN信息进行比较; 当本端的PLMN信息与本端存储的MME的PLMN信息完全一致时，eNB向MME（102）发送配置更新请求; 或者当它们部分一致时，eNB向MME发送配置更新请求和报警（103）; 或者当本端的PLMN信息与存储在本端的MME的PLMN信息完全不一致时，eNB报警（104）。

64. 发明申请

US20140217960A1 SELF-ADAPTING VOLTAGE AMPLIFIER AND BATTERY CHARGER DETECTION 有权
标题翻译：自适应电压放大器和电池充电器检测
公开(公告)号：US20140217960A1
公开(公告)日：2014-08-07
申请号：US13958600
申请日：2013-08-04
申请人： Wenzhong Zhang , Shayan Zhang , Yi Zhao
发明人： Wenzhong Zhang , Shayan Zhang , Yi Zhao
IPC分类号： H02J7/00 , H03F3/45
CPC分类号： H02J7/0052 , H02J2007/0062 , H03F3/45183
摘要： An amplifier applies a self-adapting voltage to an output terminal. A bias circuit provides a greater bias current in a first external connection condition, in the absence of a pull-up resistance connected to the output terminal, than when such a pull-up resistance is present. The amplifier applies a different voltage to the output terminal in the absence of a pull-up resistance than when such a pull-up resistance is present. The circuit can be used in a portable device for receiving charging current from a battery charger through a connector having a D+ pin for connection to the battery charger and connected to the amplifier output terminal for battery charger detection. The portable device can meet the USB battery charger specification rev. 1.2.
摘要翻译：放大器将自适应电压施加到输出端子。在不存在连接到输出端子的上拉电阻的情况下，偏置电路在第一外部连接状态下提供更大的偏置电流，而不是存在这样的上拉电阻。在不存在上拉电阻的情况下，放大器对输出端子施加不同的电压，而不是存在这样的上拉电阻。该电路可以用在便携式设备中，用于通过具有用于连接到电池充电器的D +引脚的连接器从电池充电器接收充电电流，并连接到用于电池充电器检测的放大器输出端子。便携式设备可以满足USB电池充电器规格的修改。 1.2。

65. 发明申请

US20140057927A1 INHIBITORS OF BETA-SECRETASE 有权
标题翻译： BETA-SECRETASE的抑制剂
公开(公告)号：US20140057927A1
公开(公告)日：2014-02-27
申请号：US14011183
申请日：2013-08-27
申请人： Yuri Bukhtiyarov , Salvacion Cacatian , Lawrence Wayne Dillard , Klaus Fuchs , Lanqi Jia , Deepak S. Lala , Angel Morales-Ramos , Suresh B. Singh , Shankar Venkatraman , Zhenrong Xu , Jing Yuan , Yi Zhao , Yajun Zheng , Cornelia Dorner-Ciossek , Ulrike Gross , Niklas Heine , Achim Sauer
发明人： Yuri Bukhtiyarov , Salvacion Cacatian , Lawrence Wayne Dillard , Klaus Fuchs , Lanqi Jia , Deepak S. Lala , Angel Morales-Ramos , Suresh B. Singh , Shankar Venkatraman , Zhenrong Xu , Jing Yuan , Yi Zhao , Yajun Zheng , Cornelia Dorner-Ciossek , Ulrike Gross , Niklas Heine , Achim Sauer
IPC分类号： C07D405/06 , C07D401/06 , C07D401/14 , C07D235/02 , C07D403/04
CPC分类号： C07D235/02 , A61K31/4184 , A61K31/4439 , A61K31/506 , C07C49/747 , C07C49/755 , C07C229/50 , C07C255/59 , C07C313/06 , C07C331/26 , C07C2603/94 , C07C2603/97 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D405/06
摘要： The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.
摘要翻译：本发明涉及螺环酰基胍及其作为β-分泌酶（BACE1）活性抑制剂的用途，含有它们的药物组合物及其用作治疗神经变性疾病的治疗剂的方法，其特征在于认知衰退，认知障碍，痴呆和以β-淀粉样蛋白聚集体生产为特征的疾病。

66. 发明申请

US20130279330A1 ACCESS CONTROL METHOD AND DEVICE 有权
标题翻译：访问控制方法和设备
公开(公告)号：US20130279330A1
公开(公告)日：2013-10-24
申请号：US13978402
申请日：2012-01-10
申请人： Yuan Feng , Haiyang Quan , Jiayi Fang , Yi Zhao
发明人： Yuan Feng , Haiyang Quan , Jiayi Fang , Yi Zhao
IPC分类号： H04W28/02
CPC分类号： H04W28/0247 , H04W48/06 , H04W92/14
摘要： Disclosed is an access control method, for use in implementing improved access control. The method comprises: during a random access process, on the basis of a current load of a random access network (RAN) and a core network (CN) and of terminal or service information reported by a user equipment (UE), the RAN judging whether or not access to the RAN and to the CN is allowed; when access is denied by at least one network between the RAN and the CN, the RAN transmitting to the UE an instruction message having attached therein a backoff time corresponding to the access denying network. Also disclosed is a device for implementing the method.
摘要翻译：公开了一种访问控制方法，用于实现改进的访问控制。该方法包括：在随机接入过程中，基于随机接入网（RAN）和核心网（CN）的当前负载以及由用户设备（UE）报告的终端或业务信息，RAN判断是否允许对RAN和CN的接入; 当在RAN和CN之间的至少一个网络拒绝接入时，RAN向UE发送指示消息，其中附加有对应于接入拒绝网络的退避时间。还公开了一种用于实现该方法的装置。

67. 发明授权

US08565576B2 Optical disc for reproducing stereoscopic video image 有权
标题翻译：用于再现立体视频图像的光盘
公开(公告)号：US08565576B2
公开(公告)日：2013-10-22
申请号：US12989950
申请日：2009-05-01
申请人： Tao Chen , Yoshiichiro Kashiwagi , Hisao Sasai , Yi Zhao
发明人： Tao Chen , Yoshiichiro Kashiwagi , Hisao Sasai , Yi Zhao
IPC分类号： H04N5/932
CPC分类号： H04N5/85 , G11B27/322 , G11B2220/2541 , H04N9/8205 , H04N13/161 , H04N13/178 , H04N13/189 , H04N13/359 , H04N19/597 , H04N19/61 , H04N19/70
摘要： [Problem] To provide an optical disc whose monoscopic and stereoscopic video images recorded thereon can be respectively played back on a playback device incapable of 3D display and on a 3D-capable playback device.[Means to Solve Problem] An optical disc includes an AV data recording and a navigation information area. The AV data recording area has TS, having a plurality of TSPBs and TSSBs are arranged in an interleaved manner, recorded thereon. TSPBs constitute a video stream representing monoscopic video. TSSBs constitute a video stream representing parallax video corresponding to the monoscopic video. The navigation information area has navigation information recorded therein. The navigation information has base location information and enhanced location information that is used only for stereoscopic video playback. The base location information indicates an area in which TSPBs are recorded. The enhanced location information indicates an area in which TSSBs are recorded.
摘要翻译： [问题]提供其上记录有单视和立体视频图像的光盘可以分别在不能3D显示的播放装置上和在具有3D能力的回放装置上重播。解决问题的手段光盘包括AV数据记录和导航信息区域。 AV数据记录区域具有多个TSPB和TSSB以交错方式排列的TS，记录在其上。 TSPB构成代表单视频视频的视频流。 TSSB构成表示对应于单视场视频的视差视频的视频流。导航信息区域具有记录在其中的导航信息。导航信息具有仅用于立体视频播放的基本位置信息和增强位置信息。基地址信息表示记录TSPB的区域。增强位置信息表示记录TSSB的区域。

68. 发明申请

US20120218988A1 METHOD, APPARATUS AND SYSTEM FOR UPLINK SYNCHRONIZATION 有权
标题翻译：上网同步的方法，装置和系统
公开(公告)号：US20120218988A1
公开(公告)日：2012-08-30
申请号：US13504922
申请日：2010-10-29
申请人： Fangli Xu , Yali Zhao , Jiamin Liu , Yi Zhao
发明人： Fangli Xu , Yali Zhao , Jiamin Liu , Yi Zhao
IPC分类号： H04W56/00
CPC分类号： H04W56/0045
摘要： A method, an apparatus and a system for uplink synchronization are disclosed by the embodiment of the invention. The method includes the following steps: a network equipment configures multi-carrier operation mode for a user equipment and obtains the timing advance TA group message corresponding to each of component carrier CC of the user equipment; the network equipment maintains the TA timer of each TA group according to the TA group information to be uplink synchronized with the user equipment. The embodiment of the invention provides the establishment and maintenance mechanism for uplink synchronization in the case that the timing advance of each component carrier CC is different in the multi-carrier system.
摘要翻译：本发明的实施例公开了一种用于上行链路同步的方法，装置和系统。该方法包括以下步骤：网络设备为用户设备配置多载波操作模式，并获取与用户设备的每个分量载波CC相对应的定时提前TA组消息; 网络设备根据TA组信息维护每个TA组的TA定时器，以与用户设备上行同步。在多载波系统中每个分量载波CC的定时提前不同的情况下，本发明的实施例提供了用于上行链路同步的建立和维护机制。

69. 发明授权

US08238365B2 Method and device for supporting optical transmission network service dispatch in optical synchronization network 有权
标题翻译：光同步网络支持光传输网络业务调度的方法和装置
公开(公告)号：US08238365B2
公开(公告)日：2012-08-07
申请号：US12519738
申请日：2006-12-26
申请人： Yi Zhao , Chu Ke
发明人： Yi Zhao , Chu Ke
IPC分类号： H04L29/00
CPC分类号： H04J3/167 , H04J2203/0089
摘要： A method and device for supporting optical transmission network service dispatch in an optical synchronization network, said device comprises service cards (401, 407), backplane interface (404) and a plurality of dispatch units (405, 406), wherein, the service cards (401, 407) process the service signals and distribute them to the backplane structure frame according to the bandwith of the service signals, and connect with the corresponding dispatch units (405, 406) through the backplane structure frame, and then the dispatch units (405, 406) execute the service dispatch. Said dispatch units (405, 406) can work independently from each other, and the dispatch units can be added linearly according to the bandwidth of the signal. The present invention can compatibly implement the uniform dispatch of the ODU and SDH service on the basis of the existing optical synchronization device without changing the backplane frame structure or increasing the backplane speed.
摘要翻译：一种用于在光同步网络中支持光传输网络服务调度的方法和装置，所述设备包括业务卡（401,407），背板接口（404）和多个调度单元（405,406），其中，服务卡（401,407）处理服务信号并根据服务信号的带宽将其分配到背板结构框架，并通过背板结构框架与相应的调度单元（405,406）连接，然后将调度单元 405,406）执行服务调度。所述调度单元（405,406）可以彼此独立地工作，并且可以根据信号的带宽线性地添加调度单元。本发明可以在现有的光同步装置的基础上，兼容地实现ODU和SDH业务的均匀调度，而不需要改变背板帧结构或增加背板速度。

70. 发明申请

US20120142361A1 Method, Device and System for Reconfiguring Aggregation Cell 有权
标题翻译：重新配置聚合单元的方法，设备和系统
公开(公告)号：US20120142361A1
公开(公告)日：2012-06-07
申请号：US13390105
申请日：2010-09-15
申请人： Yi Zhao , Jing Liang , Jiamin Liu , Fangli Xu
发明人： Yi Zhao , Jing Liang , Jiamin Liu , Fangli Xu
IPC分类号： H04W40/00
CPC分类号： H04W36/28 , H04L5/001 , H04L5/0053 , H04L5/0096 , H04L5/0098 , H04W72/02
摘要： The present invention provides a method for reconfiguring an aggregated cell, which includes that: a network side device judges whether the aggregated cell of a user equipment (UE) needs to be changed in the cell set in which the carriers can be aggregated; when the judgment result is that the change is needed, the network side device transmits a radio resource control (RRC) connection reconfiguration message to the UE, and the RRC connection reconfiguration message carries the change information of the aggregated cell of the UE; the UE receives the RRC connection reconfiguration message, and reconfigures the aggregated cell according to the RRC connection reconfiguration message. In the present invention, for the LTE-A system, when the aggregated cell of UE which supports the carrier aggregation changes within the same cell set in which the carriers can be aggregated, the aggregated cell of the UE can be reconfigured; and the same access stratum (AS) key is used to perform the security processing procedure for the data, which enables the uninterrupted transmission for the data.
摘要翻译：本发明提供了一种重新配置聚合小区的方法，包括：网络侧设备判断在可以聚合载波的小区集中是否需要改变用户设备（UE）的聚合小区; 当判断结果是需要改变时，网络侧设备向UE发送无线资源控制（RRC）连接重配置消息，RRC连接重配置消息携带UE的聚合小区的改变信息; UE接收RRC连接重配置消息，根据RRC连接重配置消息重新配置聚合小区。在本发明中，对于LTE-A系统，当支持载波聚合的UE的聚合小区在可以聚合载波的相同小区集中改变时，UE的聚合小区可以被重新配置; 并且使用相同的接入层（AS）密钥来执行数据的安全处理过程，这使得数据的不间断传输成为可能。

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