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61. 发明申请

US20150099693A1 Anti-Inflammatory Peptides and Composition Comprising the Same 有权
标题翻译：抗炎肽及其组成
公开(公告)号：US20150099693A1
公开(公告)日：2015-04-09
申请号：US14400321
申请日：2013-03-15
申请人： Sang Jae KIM , KAEL-GEMVAX Co., LTD. , GEMVAX AS
发明人： Sang Jae Kim , Kyun Hee Kim , Kyu-Yong Lee , Seong-Ho Koh , Hyun-Hee Park , Sung Jin Huh , Woo Jin Lee , Bum Joon Kim
IPC分类号： C07K14/47 , C07K7/08
CPC分类号： A61K38/45 , A23L33/18 , A23V2002/00 , A61K8/64 , A61K38/00 , A61Q19/00 , C07K7/08 , C07K14/4703 , C12N9/0069 , C12N9/0083 , C12Y113/11 , C12Y114/99001 , C12Y207/07049 , Y02A50/385 , Y02A50/411 , Y02A50/422
摘要： The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises at least one amino acid sequence among SEQ ID NO: 2 to SEQ ID NO: 179, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, the peptides that have at least one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 179 shows outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.
摘要翻译：本发明涉及具有抗炎活性的肽，其中肽包含SEQ ID NO：2至SEQ ID NO：179中的至少一个氨基酸序列，该肽具有高于80％的氨基酸序列的同源性，或者肽是上述肽的片段。本发明还涉及包含上述肽的炎症组合物。根据本发明，具有至少一个SEQ ID NO：2至SEQ ID NO：179的氨基酸序列的肽在抑制炎症和预防手段中表现出突出的功效。因此，包含本发明的肽的组合物可用作抗炎药物组合物或化妆品组合物，反过来，用于治疗和预防多种不同类型的炎性疾病。

62. 发明申请

US20150099692A1 Anti-Inflammatory Peptides and Composition Comprising the Same 有权
标题翻译：抗炎肽及其组成
公开(公告)号：US20150099692A1
公开(公告)日：2015-04-09
申请号：US14400291
申请日：2013-05-07
申请人： Sang Jae KIM , KAEL-GEMBAX CO., LTD. , GEMVAX AS
发明人： Sang Jae Kim , Kyung Hee Kim , Kyu-Yong Lee , Seong-Ho Koh , Hyun-Hee Park , Sung Jin Huh , Woo Jin Lee , Bum Joon Kim
IPC分类号： C07K7/08 , A23L1/305 , A61K8/64
CPC分类号： A61K38/45 , A23L33/18 , A23V2002/00 , A61K8/64 , A61K38/00 , A61Q19/00 , C07K7/08 , C07K14/4703 , C12N9/0069 , C12N9/0083 , C12Y113/11 , C12Y114/99001 , C12Y207/07049 , Y02A50/385 , Y02A50/411 , Y02A50/422
摘要： The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises SEQ ID NO: 1, the peptide has above 80% homology of amino acid sequence with above-mentioned sequence, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide comprising a sequence of SEQ ID NO: 1 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptide of this invention can be used as anti-inflammatory pharmaceutical composition or as cosmetic composition, in turn, treating and preventing a variety of different types of inflammatory diseases.
摘要翻译：本发明涉及具有抗炎活性的肽，其中肽包含SEQ ID NO：1，该肽与上述序列具有高于80％的氨基酸序列的同源性，或者肽是上述序列的片段，提及的肽。本发明还涉及包含上述肽的炎症组合物。根据本发明，包含SEQ ID NO：1的序列的肽在抑制炎症和预防手段中具有突出的功效。因此，包含本发明的肽的组合物可以用作抗炎药物组合物或化妆品组合物，反过来也可用于治疗和预防多种不同类型的炎性疾病。

63. 发明授权

US08508696B2 Polarizing plate and display apparatus having the same 有权
标题翻译：具有相同的偏光板和显示装置
公开(公告)号：US08508696B2
公开(公告)日：2013-08-13
申请号：US12845637
申请日：2010-07-28
申请人： Kwang-Hyun Kim , Ki-Chul Shin , Seung-Hee Lee , Ji-Hoon Kim , Sang-Jae Kim
发明人： Kwang-Hyun Kim , Ki-Chul Shin , Seung-Hee Lee , Ji-Hoon Kim , Sang-Jae Kim
IPC分类号： G02F1/1335
CPC分类号： G02F1/133502 , G02B5/3083 , G02F2001/133541 , G02F2001/133638 , G02F2413/02
摘要： A display apparatus comprises a display panel, a first polarizing plate and a second polarizing plate. The display panel comprises a first substrate including a pixel electrode, a second substrate opposite to the first substrate, and a liquid crystal layer disposed between a first surface of the first substrate and a first surface of the second substrate. The first polarizing plate comprises a first polarizer having a first polarizing axis, and a first λ/4 phase difference plate having a refractive index between about 1.35 and about 2.05 in a thickness direction. The second polarizing plate comprises a second polarizer having a second polarizing axis crossing the first polarizing axis, and a second λ/4 phase difference plate having a refractive index between about 1.35 and about 2.05 in a thickness direction. Accordingly, light leakage in a side view may be reduced and viewing angle may be improved.
摘要翻译：显示装置包括显示面板，第一偏振片和第二偏振片。显示面板包括：第一基板，包括像素电极，与第一基板相对的第二基板;以及液晶层，设置在第一基板的第一表面和第二基板的第一表面之间。第一偏振板包括具有第一偏振轴的第一偏振片和厚度方向上折射率约为1.35至约2.05的第一λ/ 4相位差板。第二偏振板包括具有与第一偏振轴交叉的第二偏振轴的第二偏振片和在厚度方向上的折射率在约1.35和约2.05之间的第二λ/ 4相位差板。因此，可以减小侧视图中的漏光，并且可以提高视角。

64. 发明申请

US20130107160A1 TRANSPARENT DISPLAY APPARATUS 审中-公开
标题翻译：透明显示设备
公开(公告)号：US20130107160A1
公开(公告)日：2013-05-02
申请号：US13433670
申请日：2012-03-29
申请人： Daewon KIM , Kwang-Hyun KIM , Sang-Jae KIM , Ji-Hoon KIM , Taeho KIM , Seungbeom PARK , Beong-hun BEON , NaYoung SHIN , Seunghee LEE
发明人： Daewon KIM , Kwang-Hyun KIM , Sang-Jae KIM , Ji-Hoon KIM , Taeho KIM , Seungbeom PARK , Beong-hun BEON , NaYoung SHIN , Seunghee LEE
IPC分类号： G02F1/13357 , H01J9/00
CPC分类号： G09F9/35
摘要： A transparent display apparatus includes a housing including an opening portion which extends through a surface at a viewing side thereof, the housing accommodating an object, a liquid crystal display panel at a front of the object and adjacent to the opening portion, a first polarizing plate between the opening portion and the liquid crystal display panel, a second polarizing plate at a rear of the object, a first reflective plate at a rear of the second polarizing plate a light source adjacent to the object.
摘要翻译：一种透明显示装置，包括壳体，该壳体包括在其观察侧的表面延伸的开口部，容纳物体的壳体，位于物体的前方且与开口部相邻的液晶显示面板，第一偏振片在所述开口部和所述液晶显示面板之间，在所述物体的后方具有第二偏振片，在所述第二偏振片的后方的与所述物体相邻的光源的第一反射板。

65. 发明申请

US20110085113A1 POLARIZING PLATE AND DISPLAY APPARATUS HAVING THE SAME 有权
标题翻译：偏光板和显示装置
公开(公告)号：US20110085113A1
公开(公告)日：2011-04-14
申请号：US12845637
申请日：2010-07-28
申请人： Kwang-Hyun Kim , Ki-Chul Shin , Seung-Hee Lee , Ji-Hoon Kim , Sang-Jae Kim
发明人： Kwang-Hyun Kim , Ki-Chul Shin , Seung-Hee Lee , Ji-Hoon Kim , Sang-Jae Kim
IPC分类号： G02F1/1335 , G02B5/30
CPC分类号： G02F1/133502 , G02B5/3083 , G02F2001/133541 , G02F2001/133638 , G02F2413/02
摘要： A display apparatus comprises a display panel, a first polarizing plate and a second polarizing plate. The display panel comprises a first substrate including a pixel electrode, a second substrate opposite to the first substrate, and a liquid crystal layer disposed between a first surface of the first substrate and a first surface of the second substrate. The first polarizing plate comprises a first polarizer having a first polarizing axis, and a first λ/4 phase difference plate having a refractive index between about 1.35 and about 2.05 in a thickness direction. The second polarizing plate comprises a second polarizer having a second polarizing axis crossing the first polarizing axis, and a second λ/4 phase difference plate having a refractive index between about 1.35 and about 2.05 in a thickness direction. Accordingly, light leakage in a side view may be reduced and viewing angle may be improved.
摘要翻译：显示装置包括显示面板，第一偏振片和第二偏振片。显示面板包括：第一基板，包括像素电极，与第一基板相对的第二基板;以及液晶层，设置在第一基板的第一表面和第二基板的第一表面之间。第一偏振片包括具有第一偏振轴的第一偏振片和在厚度方向上的折射率在约1.35和约2.05之间的第一λ/ 4相位差板。第二偏振片包括具有与第一偏振轴交叉的第二偏振轴的第二偏振片和在厚度方向上的折射率在约1.35和约2.05之间的第二λ/ 4相位差板。因此，可以减小侧视图中的漏光，并且可以提高视角。

66. 发明授权

US06573526B1 Single electron tunneling transistor having multilayer structure 失效
标题翻译：具有多层结构的单电子隧穿晶体管
公开(公告)号：US06573526B1
公开(公告)日：2003-06-03
申请号：US10019430
申请日：2002-04-19
申请人： Tsutomu Yamashita , Sang-Jae Kim
发明人： Tsutomu Yamashita , Sang-Jae Kim
IPC分类号： H01L2906
CPC分类号： H01L29/7613 , B82Y10/00 , H01L39/221 , H01L39/228
摘要： A single electron tunneling transistor which has a multi-layer structure exhibiting a single electron tunneling effect even with processing accuracy of not greater than 0.1 &mgr;m. The multi-layer structure of the single electron tunneling transistor is characterized by alternately growing an electrically conductive layer and a tunneling barrier layer. The number of layers is 50 or more. The structure has a minute tunneling junction having an area on the order of 1 &mgr;m square.
摘要翻译：具有即使加工精度不大于0.1μm的单电子隧道效应的多层结构的单电子隧穿晶体管。单电子隧穿晶体管的多层结构的特征在于交替地生长导电层和隧道势垒层。层数为50以上。该结构具有具有约1平方英寸的面积的微小隧道结。

67. 发明申请

US20210062167A1 Cell Penetrating Peptide, Conjugate Comprising Same, and Composition Comprising Conjugate 有权
公开(公告)号：US20210062167A1
公开(公告)日：2021-03-04
申请号：US17032781
申请日：2020-09-25
申请人： GemVax & KAEL CO., LTD. , Sang Jae KIM
发明人： Sang Jae KIM
IPC分类号： C12N9/12 , A23L33/18 , C07K14/00 , A61K49/00 , C07K7/08 , A61K8/64 , A61K8/66 , A61Q19/00 , G01N33/58 , A61K47/64
摘要： The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 156, a fragment of any one sequence of SEQ ID NO: 1 to SEQ ID NO: 156, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.

68. 发明授权

US10822595B2 Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate 有权
公开(公告)号：US10822595B2
公开(公告)日：2020-11-03
申请号：US15869518
申请日：2018-01-12
申请人： GemVax & KAEL CO., LTD. , Sang Jae KIM
发明人： Sang Jae Kim
IPC分类号： C07K14/00 , C12N9/12 , A23L33/18 , A61K49/00 , C07K7/08 , A61K8/64 , A61K8/66 , A61Q19/00 , G01N33/58 , A61K47/64 , A61K38/00
摘要： The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 156, a fragment of any one sequence of SEQ ID NO: 1 to SEQ ID NO: 156, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.

69. 发明授权

US10676507B2 Peptide and composition containing the same for anti-inflammation, anti-fibrosis, wound healing, and anticancer treatment 有权
公开(公告)号：US10676507B2
公开(公告)日：2020-06-09
申请号：US15576111
申请日：2016-05-25
申请人： GemVax & KAEL CO., LTD. , Sang Jae Kim
发明人： Sang Jae Kim
IPC分类号： A61K38/08 , A61K38/10 , A61K38/00 , C07K7/06 , C07K7/08 , C07K7/00 , C07K14/00 , A61P29/00 , A61P17/02 , A61P17/06 , A61P17/00 , A61P19/02 , A61P1/00 , A61P1/04 , A61P1/16 , A61P25/00 , A61P35/00 , A61P37/00 , A61P3/10 , A61P19/00 , A61P11/00
摘要： Peptides and compositions comprising the peptides, and more particularly, a peptide effective in anti-inflammation, anti-fibrosis, wound healing, and anti-cancer treatment, and a composition including the same are described. The peptides provided herein and the compositions comprising the peptides exhibit an effect of alleviating, preventing, or treating inflammation, fibrosis, wounds, and symptoms of diseases such as cancer including these symptoms, and thus may provide a method of preventing or treating associated diseases.

70. 发明授权

US10561703B2 Method of modulating sex hormone levels using a sex hormone secretion modulator 有权
公开(公告)号：US10561703B2
公开(公告)日：2020-02-18
申请号：US14899746
申请日：2014-06-23
申请人： GEMVAX & KAEL CO., LTD. , Sang Jae Kim
发明人： Sang Jae Kim
IPC分类号： A61K38/10 , A61K39/39 , A61K38/45 , C12N9/12 , C07K14/575 , C07K7/08
摘要： Provided are a hormone secretion modulator including a peptide derived from telomerase, more particularly, a peptide including an amino acid sequence of SEQ ID NO: 1, an amino acid sequence having a sequence identity of at least 80% with SEQ ID NO: 1, or a fragment thereof, a pharmaceutical composition including the hormone secretion modulator, and a use of the pharmaceutical composition for treatment, alleviation, or prevention of diseases caused by excessive or deficient levels hormones.

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