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61. 发明申请

US20040079894A1 Eye protection system on an electronically controlled fluorescence microscope 失效
标题翻译：电子荧光显微镜上的眼睛保护系统
公开(公告)号：US20040079894A1
公开(公告)日：2004-04-29
申请号：US10692368
申请日：2003-10-23
申请人： Leica Microsystems (Schweiz) AG
发明人： Paul Graefenhain
IPC分类号： G01N021/64
CPC分类号： G02B21/16
摘要： The invention concerns a fluorescence (stereo)microscope having a filter carrier that can be loaded with manually exchangeable filter inserts, and having a reliable eye protection system against the energy-rich light radiation in the context of a carrier position without a filter insert.
摘要翻译：本发明涉及一种荧光（立体）显微镜，其具有可装载手动可更换过滤器插件的过滤器载体，并且在没有过滤器插入件的载体位置的上下文中具有抵抗能量丰富的光辐射的可靠的眼睛保护系统。

62. 发明申请

US20030161037A1 Illumination incoupling system for an optical viewing device 失效
标题翻译：用于光学观察装置的照明耦合系统
公开(公告)号：US20030161037A1
公开(公告)日：2003-08-28
申请号：US10374913
申请日：2003-02-26
申请人： Leica Microsystems (Schweiz) AG
发明人： Ulrich Sander
IPC分类号： G02B021/22
CPC分类号： G02B21/20 , A61B3/132 , A61B90/30 , A61B90/36 , G02B21/06
摘要： In an illumination incoupling system for an optical viewing device, illumination incoupling is provided simultaneously into main observer beam paths and assistant observer beam paths using two semitransparent and two fully reflective deflection elements arranged crosswise and symmetrically with respect to the optical axis of the main objective. Homogeneous illumination of the specimen field may thereby be achieved for both the main observer and the assistant observer.
摘要翻译：在用于光学观察装置的照明去耦系统中，使用相对于主要目标的光轴交叉和对称地布置的两个半透明和两个全反射偏转元件，同时向主观测器光束路径和辅助观察者光束路径提供照明耦合。因此，可以为主观察者和辅助观察者实现样本场的均匀照明。

63. 发明授权

US10877258B2 Microscope 有权
公开(公告)号：US10877258B2
公开(公告)日：2020-12-29
申请号：US15515642
申请日：2015-07-15
申请人： LEICA MICROSYSTEMS (SCHWEIZ) AG
发明人： Marc Honegger , Harald Schnitzler , Reto Zuest
IPC分类号： G02B21/36 , G02B21/24 , H04N5/232 , H04N5/225
CPC分类号： G02B21/244 , G02B21/245 , G02B21/365 , G02B21/367 , H04N5/2258 , H04N5/23212 , H04N5/232123
摘要： A microscope (10) is described, having an autofocus system (11) for executing a focusing procedure, having a first image sensor (14a), arranged in a first outcoupled beam path (12a), for acquiring a first image (16a); and a second image sensor (14b), arranged in a second outcoupled beam path (12b), for acquiring a second image (16b). The autofocus system (11) is embodied to ascertain a contrast difference based on contrast values of the first image (16a) acquired by the first image sensor (14a) and of the second image (16b) acquired by the second image sensor (14b), and to set a relative location of the focal plane (20) with respect to the object plane (22) based on the ascertained contrast difference, the first and the second image (16a, 16b) each encompassing image information furnished by the first and the second image sensor (14a, 14b) each embodied as an area sensor.

64. 外观设计

USD895710S1 Stand and pivot unit 有权
公开(公告)号：USD895710S1
公开(公告)日：2020-09-08
申请号：US29657239
申请日：2018-07-20
申请人： Leica Microsystems (Schweiz) AG
设计人： Christophe Apothéloz
摘要： This application contains subject matter related to the following co-pending U.S. design patent application:
application Ser. No. 29/542,684, filed Oct. 16, 2015 and entitled “MICROSCOPE.”
FIG. 1 is a front view of a stand and pivot unit according to the design;
FIG. 2 is a left side view thereof;
FIG. 3 is a right side view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a front, left perspective view thereof;
FIG. 6 is a top view thereof; and,
FIG. 7 is a bottom view thereof.
The broken lines are for illustrative purposes only and form no part of the claimed design.

65. 发明授权

US10591711B2 Microscope and method for obtaining a high dynamic range synthesized image of an object 有权
公开(公告)号：US10591711B2
公开(公告)日：2020-03-17
申请号：US15516149
申请日：2014-10-06
申请人： LEICA MICROSYSTEMS (SCHWEIZ) AG , LEICA INSTRUMENTS (SINGAPORE) PTE LTD
发明人： Zheng-Dong Zeng , Qing-Song Zou , Urs Schmid
IPC分类号： G02B21/36 , G02B21/06 , H04N5/235
摘要： A microscope (10) for obtaining a high dynamic range synthesized image (21) of an object (12) from a plurality of low dynamic range input images (19) comprises a controller (14), an incoherent light source (16) for illuminating the object (12) at different light intensity levels, and a recording device (18) for recording the plurality of low dynamic range input images (19), wherein each of the low dynamic range input images (19) is recorded at a different light intensity level. The controller (14) is configured to control the recording device (18) such that during recording of the series of the low dynamic range images the recording parameters for obtaining the plurality of low dynamic range input images (19) are kept constant.

66. 外观设计

USD826304S1 Stand and pivot unit 有权
公开(公告)号：USD826304S1
公开(公告)日：2018-08-21
申请号：US29542687
申请日：2015-10-16
申请人： Leica Microsystems (Schweiz) AG
设计人： Christophe Apothéloz

67. 发明申请

US20180149852A1 MICROSCOPE 审中-公开
公开(公告)号：US20180149852A1
公开(公告)日：2018-05-31
申请号：US15515635
申请日：2015-07-15
申请人： LEICA MICROSYSTEMS (SCHWEIZ) AG
发明人： Harald SCHNITZLER , Reto ZUEST , Marc HONEGGER
IPC分类号： G02B21/24 , G02B21/36 , G02B7/36 , H04N5/247 , H04N5/232
摘要： A microscope (10) is described, comprising an autofocus system (11) for executing a focusing procedure, having a first image sensor (14a), arranged in a first outcoupled beam path (12a), for acquiring a first image (16a); and a second image sensor (14b), arranged in a second outcoupled beam path (12b), for acquiring a second image (16b). The autofocus system (11) is embodied in such a way that the focusing procedure is executable on the basis of at least a first operating mode and a second operating mode.

68. 发明申请

US20170254998A1 MICROSCOPE 审中-公开
公开(公告)号：US20170254998A1
公开(公告)日：2017-09-07
申请号：US15515642
申请日：2015-07-15
申请人： LEICA MICROSYSTEMS (SCHWEIZ) AG
发明人： Marc HONEGGER , Harald SCHNITZLER , Reto ZUEST
IPC分类号： G02B21/24 , H04N5/232 , H04N5/225 , G02B21/36
CPC分类号： G02B21/244 , G02B21/245 , G02B21/365 , G02B21/367 , H04N5/2258 , H04N5/23212
摘要： A microscope (10) is described, having an autofocus system (11) for executing a focusing procedure, having a first image sensor (14a), arranged in a first outcoupled beam path (12a), for acquiring a first image (16a); and a second image sensor (14b), arranged in a second outcoupled beam path (12b), for acquiring a second image (16b). The autofocus system (11) is embodied to ascertain a contrast difference based on contrast values of the first image (16a) acquired by the first image sensor (14a) and of the second image (16b) acquired by the second image sensor (14b), and to set a relative location of the focal plane (20) with respect to the object plane (22) based on the ascertained contrast difference, the first and the second image (16a, 16b) each encompassing image information furnished by the first and the second image sensor (14a, 14b) each embodied as an area sensor.

69. 发明授权

US09606346B2 Incident illumination device for a microscope having a planar light source 有权
公开(公告)号：US09606346B2
公开(公告)日：2017-03-28
申请号：US14418623
申请日：2013-08-02
申请人： Leica Microsystems (Schweiz) AG
发明人： Robert Paulus , Harald Schnitzler , Reto Züst
IPC分类号： G02B21/06 , G02B21/08 , F21V8/00
CPC分类号： G02B21/06 , G02B6/005 , G02B6/0068 , G02B21/082
摘要： The invention relates to an incident illumination device for a microscope, for viewing a sample (1) in the microscope (10), having a planar light source (100) for incident illumination of the sample (1), wherein the planar light source (100) comprises a panel-shaped light guide having a lower boundary surface (111), an upper boundary surface, and at least one lateral surface, as well as at least one light-emitting means that is arranged so that it irradiates light, via at least one lateral surface serving as a light entry surface, into the light guide in such a way that said light propagates in the light guide due to total reflection; wherein the total reflection is disrupted in defined fashion by an element abutting at the lower boundary surface of the light guide against a contact surface so that an outcoupling of light occurs at the upper boundary surface of the light guide.

70. 发明授权

US09471984B2 Method for self-calibration of a microscope apparatus 有权
标题翻译：显微镜装置的自校准方法
公开(公告)号：US09471984B2
公开(公告)日：2016-10-18
申请号：US14132086
申请日：2013-12-18
申请人： Leica Microsystems (Schweiz) AG
发明人： Reto Zuest , Meinrad Berchtel
IPC分类号： G06T7/00 , G01B9/04 , G01B11/02 , G01B11/14 , G02B21/36 , G02B21/02
CPC分类号： G06T7/0044 , G01B9/04 , G01B11/02 , G01B11/14 , G02B21/025 , G02B21/365 , G06T7/74
摘要： A method for calibrating a microscope apparatus (1) having a variable optical magnification system (13) and a detector device (12) is disclosed. First, a calibrating mode is performed, wherein an image (50) of an object (10) is captured at a known reference magnification value, two characteristic reference points (32a, 32b) are determined in the image, a reference distance (34) between the two reference points is determined, and a correlation is determined between the reference distance and the reference magnification value. Later, a measuring mode is implemented, in which a current image (51) of the object (10) is captured at a second magnification value, the two characteristic reference points (52a, 52b) are identified therein, a current distance (54) between the current reference points is determined, and the second magnification value is determined from the current distance (54) based on the correlation between the reference distance (34) and the reference magnification value.
摘要翻译：公开了一种用于校准具有可变光学放大系统（13）和检测器装置（12）的显微镜装置（1）的方法。首先，执行校准模式，其中以已知的参考倍率值捕获对象（10）的图像（50），在图像中确定两个特征参考点（32a，32b），参考距离（34）确定两个参考点之间，并且在参考距离和参考倍率值之间确定相关性。之后，实现了以第二倍率值捕获对象（10）的当前图像（51）的两个特征参考点（52a，52b）的测量模式，当前距离（54）确定当前参考点之间，并且基于参考距离（34）和参考倍率值之间的相关性，从当前距离（54）确定第二倍率值。

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