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    • 61. 发明授权
    • Method for updating air interface key, core network node and radio access system
    • 更新空中接口密钥,核心网节点和无线接入系统的方法
    • US08938071B2
    • 2015-01-20
    • US13702842
    • 2011-03-09
    • Chengyan FengLu Gan
    • Chengyan FengLu Gan
    • H04L29/06H04L9/08H04W12/04H04W36/00H04W12/08
    • H04L9/0816H04W12/04H04W12/08H04W36/0038
    • The disclosure discloses a method for updating an air interface key, a core network node and a radio access system, wherein the method for updating an air interface key comprises: a core network node receives a relocation complete indication message from a target RNC (S502), the relocation complete indication message is configured to indicate the successful relocation of User Equipment (UE) from a source RNC to the target RNC; the core network node uses the saved traditional key and the current enhanced key to calculate a next hop enhanced key (S504); the core network node sends the next hop enhanced key to the target RNC (S506). Through the disclosure, the forward security of users is guaranteed effectively, thus the communication security of the radio access system is improved overall.
    • 本发明公开了一种用于更新空中接口密钥,核心网络节点和无线电接入系统的方法,其中用于更新空中接口密钥的方法包括:核心网络节点从目标RNC接收重定位完成指示消息(S502) 重定位完成指示消息被配置为指示用户设备(UE)从源RNC到目标RNC的成功重定位; 核心网节点使用保存的传统密钥和当前增强密钥来计算下一跳增强密钥(S504); 核心网络节点向目标RNC发送下一跳增强密钥(S506)。 通过披露,有效保证了用户的前向安全,从而提高了无线接入系统的通信安全性。
    • 63. 发明授权
    • Device and tool for cold expansion of fastener holes
    • 紧固件孔的冷膨胀装置和工具
    • US08915114B2
    • 2014-12-23
    • US13295046
    • 2011-11-18
    • Yordan Todorov MaksimovGalia Velikova Duncheva
    • Yordan Todorov MaksimovGalia Velikova Duncheva
    • B21D41/02B23P9/02
    • B23P9/025B29C67/0029
    • The invention refers to a tool for cold expansion of fastener holes. The tool comprises a mandrel (1) with a conical working part (2), a cylindrical sleeve (4) with a conical hole (5), wherein the sleeve (4) is entirely split from end to end into separate, laterally touching one another, segments (6), fixed in a cylindrical hole (14) of a threaded bush (7) and along the outer cylindrical surface (8) of the mandrel (1). The bush (7) is attached immovably to a device, fixing the segments (6), and each segment (6) gets into contact with the conical surface (2) of the mandrel (1) along only one generatrix (16), laying in the symmetry plane (17) of the respective segment (6). The advantage of the tool is in the possibility to control the degree of cold expansion.
    • 本发明涉及用于紧固件孔的冷膨胀的工具。 该工具包括具有锥形工作部分(2)的心轴(1),具有锥形孔(5)的圆柱形套筒(4),其中套筒(4)从一端到另一端完全分开成分开的横向接触的一个 另一个,固定在螺纹衬套(7)的圆柱形孔(14)中并沿着心轴(1)的外圆柱形表面(8)的段(6)。 衬套(7)不可移动地附接到装置,固定段(6),并且每个段(6)仅沿着一个母线(16)与心轴(1)的锥形表面(2)接触,铺设 在相应的段(6)的对称平面(17)中。 该工具的优点是可以控制冷膨胀的程度。
    • 64. 发明授权
    • Method of treating graft-rejection using dextran sulfate
    • 使用硫酸葡聚糖治疗移植排斥的方法
    • US08906884B2
    • 2014-12-09
    • US12685005
    • 2010-01-11
    • Bo NilssonOlle Korsgren
    • Bo NilssonOlle Korsgren
    • A61K31/721A61K35/39A61K31/737
    • A61K31/737A61K31/721A61K35/39A61L27/3804A61L27/3839A61L27/54A61L2300/232A61L2300/41A61L2300/45A61L2300/64
    • The present invention refers to use of dextran sulfate, or a pharmaceutically acceptable derivate thereof, for manufacturing of a medicament for treatment of Instant Blood-Mediated Inflammatory Reaction (IBMIR). In addition, the invention refers to the use of dextran sulfate, or a pharmaceutically acceptable derivate thereof, for manufacturing of a medicament for treatment of morphological disruption of cell transplants and graft-rejection of cell transplants caused by IBMIR. The invention may be applied to patients suffering from type I diabetes, in which porcine islets of Langerhans are transplanted in their portal vein. Administration of dextran sulfate according to the invention inhibits and prevents rejection and destruction of the transplanted islets and makes normoglycemia in the patients possible.
    • 本发明涉及使用硫酸葡聚糖或其药学上可接受的衍生物来制备用于治疗即时血液介导的炎性反应(IBMIR)的药物。 此外,本发明涉及硫酸葡聚糖或其药学上可接受的衍生物在制备用于治疗由IBMIR引起的细胞移植的形态学破坏和细胞移植的移植排斥的药物中的用途。 本发明可以应用于患有I型糖尿病的患者,其中在其门静脉中移植了朗格汉斯猪胰岛。 根据本发明的硫酸葡聚糖的施用抑制并防止移植胰岛的排斥和破坏,并使患者的血糖异常成为可能。
    • 66. 发明授权
    • Oligonucleotides related to lipid membrane attachment
    • 与脂质膜附着相关的寡核苷酸
    • US08901046B2
    • 2014-12-02
    • US13784550
    • 2013-03-04
    • Bio-Rad Laboratories Inc.
    • Indriati PfeifferFredrick Höök
    • B01J19/00C07H21/00A61K47/48
    • B01J19/0046A61K47/549A61K47/554C07H21/00
    • A method of forming a lipid membrane attached linker comprises contacting a lipid membrane with an oligonucleotide having a first strand and a second strand of nucleic acid and two or more hydrophobic anchoring moieties located in its terminal ends. The two strands are hybridized to each other in a duplex section in a manner that the first strand terminal end is not a part of the duplex section and free from a hydrophobic anchoring moiety and the two or more hydrophobic anchoring moieties are covalently attached to the adjacent terminal ends of the first strand and the second strand of said oligonucleotide, thereby accomplishing a direct attachment of the oligonucleotide by the moieties on the same membrane.
    • 形成脂质膜连接接头的方法包括使脂质膜与位于其末端的具有第一链和第二条核酸的寡核苷酸和两个或更多个疏水性锚定部分接触。 两条链在双链体部分中彼此杂交,使得第一链末端不是双链体部分的一部分并且不具有疏水性锚定部分,并且两个或更多个疏水性锚定部分共价连接到相邻的 第一链的末端和所述寡核苷酸的第二链,从而通过在相同膜上的部分直接附着寡核苷酸。