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51. 发明授权

US08834499B2 Percutaneous methods and apparatus for creating native tissue venous valves 有权
标题翻译：用于创建本地组织静脉瓣的经皮方法和装置
公开(公告)号：US08834499B2
公开(公告)日：2014-09-16
申请号：US13892573
申请日：2013-05-13
申请人： Medtronic Vascular, Inc.
发明人： Kevin Mauch , Maria Arreguin
IPC分类号： A61B17/32 , A61B17/3207 , A61M25/10 , A61B8/08 , A61F2/24 , A61B17/3209 , A61B17/22 , A61B8/12 , A61B17/00 , A61M25/01
CPC分类号： A61B17/320725 , A61B8/0841 , A61B8/12 , A61B17/3209 , A61B2017/00783 , A61B2017/22061 , A61F2/2463 , A61F2/2475 , A61M25/0105 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1081
摘要： Percutaneous methods and apparatuses for forming a venous valve from autologous tissue. A catheter having a retractable dissecting system received therein is delivered to a target location where a new venous valve is to be created. A distal balloon or other radially-expandable component mounted on the catheter is expanded against the vein wall, and the dissecting system is proximally retracted to deploy one or more dissecting components that dissect a subintimal layer of the vein wall. Radial expansion of the dissecting component(s) within the vein wall creates one or more leaflets and corresponding pocket/sinuses in the vein that collectively act as a venous valve, and/or the radially-expandable component of the catheter is subsequently collapsed such that the dissecting component(s) each pull a flap of the dissected tissue towards the vein lumen to create one or more leaflet(s) and corresponding pocket/sinuses in the vein.
摘要翻译：用于从自体组织形成静脉瓣的经皮方法和装置。将其中容纳有可伸缩解剖系统的导管输送到要创建新静脉瓣的目标位置。安装在导管上的远端球囊或其他可径向扩张的部件相对于静脉壁膨胀，并且解剖系统向近端缩回以展开解剖静脉壁的内膜层的一个或多个解剖部件。静脉壁内的解剖组件的径向扩张在静脉中产生一个或多个小叶和相应的静脉中的口袋/鼻窦，其共同作为静脉瓣，并且/或导管的可径向膨胀的组分随后被压扁，使得解剖组件每个将解剖组织的瓣片拉向静脉腔，以在静脉中产生一个或多个小叶和相应的口袋/鼻窦。

52. 发明授权

US08771305B2 Lateral intravascular excision/incision devices 失效
标题翻译：横向血管内切除/切口装置
公开(公告)号：US08771305B2
公开(公告)日：2014-07-08
申请号：US12268835
申请日：2008-11-11
申请人： Edgar Louis Shriver
发明人： Edgar Louis Shriver
IPC分类号： A61B17/14 , A61B17/32
CPC分类号： A61B17/3209 , A61B17/32053 , A61B17/320758 , A61B2017/00252 , A61B2017/00398 , A61B2017/1135 , A61B2017/22055 , A61B2017/22061 , A61B2017/306 , A61B2017/320064 , A61B2017/320791
摘要： A lateral incision catheter device is described which has a first shell formed as a hollow semi-spherical surface of hard, rigid material with circumference approximately that of half a true circle, and having a longitudinal axis longer or shorter than that of a true circle, and the shell edge on each side of the longitudinal axis being a cutting surface, and with a first catheter passing through and being bonded to the first shell on the longitudinal axis of the first shell near the distal end of the first catheter and a second shell essentially the same as the first but slightly larger and bonded to the distal end of a slightly larger catheter so as to surround the first and having an opening on the longitudinal axis for the distal end of first catheter to enter and thus serve as the axis for both concentric shells. A practitioner advances the lateral incision catheter to a pre-selected site in the lumen of a blood vessel, rotates one or both catheters to properly position the shells radially then rotates the first catheter and second catheter in opposite directions so the cutting surfaces of the shell edges engage adjacent tissue to cut out and remove a section of patient's lumen wall between the closing shell edges, and after the first and the second shells have rotated about 180 degrees they constitute a substantially closed container holding the excised portion of lumen wall which may be removed from the blood vessel by retraction of the lateral incision catheter. The device may be introduced through and used in a hemostatic guiding catheter which prevents blood from escaping though the opening on the lumen wall after the opening is made.
摘要翻译：描述了一种侧切口导管装置，其具有形成为硬的刚性材料的中空半球形表面的第一壳体，其圆周大约为正圆的半数，并且具有比真圆圆形更长或更短的纵向轴线，并且所述纵向轴线的每一侧上的外壳边缘是切割表面，并且第一导管穿过第一壳体并且在第一壳体的靠近第一导管的远端的纵向轴线上并且结合到第一壳体，并且第二壳体基本上与第一但稍微较大并且与较大导管的远端相同，以便围绕第一并且在纵向轴线上具有用于第一导管的远端的开口进入并因此用作两个同心贝壳。从业者将侧切口导管推进到血管内腔中的预选位置，旋转一个或两个导管以径向适当地定位壳体，然后使第一导管和第二导管沿相反方向旋转，从而壳体的切割表面边缘接合邻近的组织以切除和去除关闭的外壳边缘之间的一部分患者的管腔壁，并且在第一和第二壳体旋转约180度之后，它们构成一个基本上密封的容器，其保持管腔壁的切除部分，通过外侧切口导管的缩回从血管中移除。该装置可以被引入并用于止血引导导管中，该止血导引导管在打开开口之后防止血液通过管腔壁上的开口逸出。

53. 发明申请

US20140155920A1 CUTTING WIRE ASSEMBLY FOR USE WITH A CATHETER 审中-公开
标题翻译：切割电线组件与导管一起使用
公开(公告)号：US20140155920A1
公开(公告)日：2014-06-05
申请号：US14176128
申请日：2014-02-09
申请人： Israel Schur , James F. McGuckin, JR. , James Erich Bressler
发明人： Israel Schur , James F. McGuckin, JR. , James Erich Bressler
IPC分类号： A61B17/3207
CPC分类号： A61B17/320725 , A61B34/20 , A61B2017/22001 , A61B2017/22061 , A61B2017/320733 , A61B2034/2046 , A61M25/104
摘要： A method of treating a lesion in a body lumen to enlarge a passageway in the lumen including inserting a cutting member and tracking member through a first lumen of a catheter, withdrawing the catheter from the cutting member and tracking member, inserting the catheter over the tracking member and leaving the cutting member outside the catheter, and expanding a portion of the catheter to move the cutting member into cutting contact with the lesion. A device for treating a lesion in a body lumen including a cutting member and tracking member is also provided.
摘要翻译：一种治疗体腔内的病变以扩大内腔中的通道的方法，包括通过导管的第一腔插入切割构件和跟踪构件，将导管从切割构件和跟踪构件中取出，将导管插入跟踪并且将切割构件离开导管，并且使导管的一部分膨胀以将切割构件移动到与损伤部分切割接触。还提供了一种用于治疗包括切割构件和跟踪构件的体腔中的损伤的装置。

54. 发明授权

US08734362B2 Minimally invasive methods and apparatus 有权
标题翻译：微创方法和装置
公开(公告)号：US08734362B2
公开(公告)日：2014-05-27
申请号：US11996944
申请日：2006-07-26
申请人： Edward M. Boyle, Jr.
发明人： Edward M. Boyle, Jr.
IPC分类号： A61B10/00 , A61B17/24 , A61B17/26 , A61B17/32
CPC分类号： A61B10/0266 , A61B10/0283 , A61B10/04 , A61B17/0057 , A61B17/12022 , A61B17/1204 , A61B17/12104 , A61B17/12159 , A61B17/221 , A61B17/320016 , A61B17/32053 , A61B17/32056 , A61B17/320725 , A61B17/32075 , A61B17/32093 , A61B18/04 , A61B18/14 , A61B18/20 , A61B34/20 , A61B2010/0006 , A61B2017/00247 , A61B2017/00296 , A61B2017/00535 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00809 , A61B2017/22034 , A61B2017/22038 , A61B2017/22061 , A61B2017/306 , A61B2018/00029 , A61B2018/00392 , A61B2018/00595 , A61B2018/0063 , A61M25/0045 , A61M25/09 , A61M25/10 , A61M2025/1013 , A61M2025/105 , A61M2025/1081 , A61M2025/1086
摘要： A lung biopsy tool having a deployable snare and an inflatable pull type cutter for removing small samples of tissue.
摘要翻译：具有可展开圈套的肺活组织检查工具和用于移除小组织样本的可充气拉式切割器。

55. 发明授权

US08702652B2 Method and apparatus for increasing blood flow through an obstructed blood vessel 有权
公开(公告)号：US08702652B2
公开(公告)日：2014-04-22
申请号：US13672323
申请日：2012-11-08
申请人： The Cleveland Clinic Foundation
发明人： David Fiorella , Henry Woo
IPC分类号： A61M31/00 , A61M37/00 , A61M29/00
CPC分类号： A61B17/22 , A61B17/221 , A61B17/320725 , A61B2017/00867 , A61B2017/00893 , A61B2017/22034 , A61B2017/22038 , A61B2017/22061 , A61B2017/22084 , A61B2017/2212 , A61B2017/320004 , A61B2017/320008 , A61B2017/320733 , A61B2017/320741 , A61M25/10 , A61M25/1027 , A61M29/02 , A61M2025/1088 , A61M2025/1095
摘要： A method of increasing blood flow through an obstructed blood vessel includes providing an expandable member substantially made of a mesh having a plurality of interstices. The expandable member is inserted into the blood vessel, positioned within the blood vessel with the proximal member end upstream of the distal member end and the member body located radially adjacent at least a portion of an obstruction, and expanded to bring at least a portion of the member body into contact with the obstruction. An outward radial force is exerted on the obstruction to dislodge at least one fragment from the obstruction and to enhance blood flow through the blood vessel past the obstruction. The at least one fragment is passed through at least one interstice of the member body in the radial direction, and is selectively retained within the expandable member.

56. 发明授权

US08702626B1 Guidewires for performing image guided procedures 有权
标题翻译：导线执行图像引导程序
公开(公告)号：US08702626B1
公开(公告)日：2014-04-22
申请号：US11648158
申请日：2006-12-29
申请人： Isaac J. Kim , Eric Goldfarb , Tom T. Vo , Robert K. Deckman
发明人： Isaac J. Kim , Eric Goldfarb , Tom T. Vo , Robert K. Deckman
IPC分类号： A61B5/05 , A61B5/00 , A61M25/00
CPC分类号： A61B5/062 , A61B5/055 , A61B5/06 , A61B5/6851 , A61B6/032 , A61B17/24 , A61B17/320725 , A61B17/320758 , A61B17/320783 , A61B17/3478 , A61B34/20 , A61B90/16 , A61B90/361 , A61B90/39 , A61B2017/22042 , A61B2017/22061 , A61B2034/2048 , A61B2034/2051 , A61B2090/363 , A61B2090/365 , A61B2090/3958 , A61B2090/3983 , A61M25/09 , A61M25/09041 , A61M29/02 , A61M2025/0166 , A61M2025/09083 , A61M2025/09175 , A61M2029/025
摘要： Guidewires and methods useable in conjunction with image guidance systems to facilitate performance of diagnostic or therapeutic tasks at locations within the bodies of human or animal subjects.
摘要翻译：导线和方法可与图像引导系统结合使用，以促进在人或动物主体的身体内的位置执行诊断或治疗任务。

57. 发明申请

US20140024903A1 Abrading Balloon Catheter for Extravasated Drug Delivery 审中-公开
标题翻译：用于外推药物输送的磨砂气球导管
公开(公告)号：US20140024903A1
公开(公告)日：2014-01-23
申请号：US14033181
申请日：2013-09-20
申请人： Lawrence J. Gerrans , Erhan H. Gunday
发明人： Lawrence J. Gerrans , Erhan H. Gunday
IPC分类号： A61M37/00 , A61M5/00 , A61B17/22 , A61M25/01 , A61B6/12 , A61M25/10 , A61B5/00 , A61B6/00
CPC分类号： A61M37/00 , A61B5/0084 , A61B5/6853 , A61B6/12 , A61B6/481 , A61B8/0833 , A61B17/22 , A61B17/22012 , A61B17/22032 , A61B17/320725 , A61B18/1492 , A61B2017/22054 , A61B2017/22061 , A61B2017/22084 , A61B2017/320004 , A61B2018/00214 , A61B2018/00898 , A61M5/007 , A61M25/0108 , A61M25/10 , A61M25/1011 , A61M25/1018 , A61M25/10181 , A61M25/10184 , A61M2025/105 , A61M2025/1086
摘要： A method of extravasated drug delivery is disclosed, including inserting a catheter with a first balloon, a second balloon, and a third balloon positioned between the first and second balloons and having a wall with an abrasive outer surface, into a bodily cavity, inflating the first and second balloons to create a chamber therebetween, stimulating a flow of blood cells by inflating the third balloon until the abrasive outer surface abrades tissue, and delivering the agent to the chamber. A balloon catheter system is also provided including a balloon having a wall with an abrasive outer surface for abrading tissue, a catheter having a first lumen for supplying fluid to the balloon to inflate the balloon such that the abrasive surface stimulates a flow of blood cells, and a second lumen for supplying an agent to tissue.
摘要翻译：公开了一种外渗药物递送的方法，包括将具有第一球囊，第二球囊和第三球囊的导管插入到第一和第二球囊之间并且具有磨料外表面的壁进入体腔，使第第一和第二气球以在其间形成室，通过使第三气囊膨胀直到研磨外表面磨损组织，并将试剂输送到腔室来刺激血细胞流。还提供了一种球囊导管系统，其包括具有用于研磨组织的具有磨料外表面的壁的气囊，具有用于向球囊供应流体以使气囊膨胀以使得研磨表面刺激血细胞流动的第一腔的导管，以及用于向组织供应药剂的第二腔。

58. 发明授权

US08632559B2 Method and system for treating valve stenosis 有权
标题翻译：治疗瓣膜狭窄的方法和系统
公开(公告)号：US08632559B2
公开(公告)日：2014-01-21
申请号：US13236449
申请日：2011-09-19
申请人： Gary Gershony , David Doty
发明人： Gary Gershony , David Doty
IPC分类号： A61B17/22 , A61D1/02
CPC分类号： A61B17/320725 , A61B17/3207 , A61B2017/22061 , A61B2017/22098 , A61B2017/320008
摘要： A valvuloplasty catheter comprises a balloon or other expansible shell which carries a plurality of scoring elements, typically formed in an elastic, self-closing metal cage. The expansible shell and scoring elements are positioned inside an aortic or other cardiac valve, and the shell expanded to engage the scoring elements against stenotic material which covers the valve leaflets and valve annulus. The scoring elements uniformly distributed force to break up the stenotic material, and the cage further contributes to rapid balloon deflation allowing shortening of the treatment time.
摘要翻译：瓣膜成形术导管包括气囊或其它可膨胀外壳，其携带多个刻痕元件，通常形成为弹性的自闭合金属笼。可膨胀的外壳和刻痕元件位于主动脉或其他心脏瓣膜内部，并且外壳扩张以将刻痕元件接合到覆盖瓣膜小叶和瓣膜环的狭窄材料上。刻痕元件均匀分布力以分解狭缝材料，并且保持架进一步有助于快速气囊缩放，从而缩短治疗时间。

59. 发明授权

US08628519B2 Rapid exchange bias laser catheter design 有权
标题翻译：快速交换偏置激光导管设计
公开(公告)号：US08628519B2
公开(公告)日：2014-01-14
申请号：US12337232
申请日：2008-12-17
申请人： Kevin D. Taylor , Wade Bowe
发明人： Kevin D. Taylor , Wade Bowe
IPC分类号： A61B18/18
CPC分类号： A61B18/245 , A61B18/24 , A61B2017/22038 , A61B2017/22061 , A61B2018/2238
摘要： Embodiments of a balloon biasing laser catheter are provided. In some embodiments, the laser catheter may include a distal tip that extends from the distal end of the catheter from a point near the light guide aperture. The distal tip may be disposed at the periphery of the catheter. In some embodiments, a balloon may be disposed between the light guide aperture and the distal tip, such that the a light guide extending from the aperture may be disposed proximate with the distal tip having the balloon in between. A retaining wire may be coupled with the distal tip and slidably coupled with the light guide. The retaining wire may keep the light guide biased relatively parallel with the distal tip and/or the catheter body when the balloon is inflated. The light guide may include a guidewire lumen the extends to the distal end of the distal tip.
摘要翻译：提供气球偏置激光导管的实施例。在一些实施例中，激光导管可以包括从导管孔附近的点从导管的远端延伸的远端尖端。远侧末端可以设置在导管的周边。在一些实施例中，球囊可以设置在光导孔和远侧末端之间，使得从孔延伸的光导可以设置成与具有气囊的远侧末端在其间附近。保持线可以与远侧末端联接并且与光导可滑动地联接。当气囊膨胀时，保持线可以保持光导偏压与远端和/或导管体相对平行。光导可以包括延伸到远侧末端的远端的导丝管腔。

60. 发明授权

US08617193B2 Balloon catheter with improved pushability 失效
标题翻译：球囊导管具有改善的推力
公开(公告)号：US08617193B2
公开(公告)日：2013-12-31
申请号：US13464407
申请日：2012-05-04
申请人： Show-Mean Wu
发明人： Show-Mean Wu
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/0054 , A61M2025/0063 , A61M2025/0183
摘要： Rapid exchange angioplasty catheters and methods of constructing rapid exchange angioplasty catheters including features that provide good pushability and kink resistance. In an illustrative embodiment, a catheter is provided, the illustrative catheter including a proximal hypotube section, which connects to a more distal braided catheter section. The braided catheter section connects to a midshaft portion that includes a guidewire entry port. Distal of the midshaft portion is a distal section having a balloon disposed thereon. An inflation lumen extends the length of the catheter, while a guidewire lumen extends only from the guidewire entry port to the distal end of the catheter. Optionally, a core wire may extend across the joint from the hypotube, to the braided catheter section, and past the guidewire entry port.
摘要翻译：快速交换血管成形术导管和构建快速交换血管成形术导管的方法，包括提供良好的推动性和扭结阻力的特征。在说明性实施例中，提供导管，所述说明性导管包括连接到更远端的编织导管部分的近端海波管部分。编织导管部分连接到包括导丝入口的中间部分。中间部分的远端是具有设置在其上的球囊的远端部分。膨胀腔延伸导管的长度，而导丝腔仅从导丝进入口延伸到导管的远端。可选地，芯线可以从海波管延伸穿过接头到编织导管部分，并且经过引导线进入端口。

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