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51. 发明申请

US20050232910A1 Anti-Listeria bacteriocin 有权
标题翻译：抗李斯特氏菌细菌素
公开(公告)号：US20050232910A1
公开(公告)日：2005-10-20
申请号：US11028505
申请日：2005-01-04
申请人： Jean-Marie Berjeaud , Christophe Fremaux , Yves Cenatiempo , Laurence Simon
发明人： Jean-Marie Berjeaud , Christophe Fremaux , Yves Cenatiempo , Laurence Simon
IPC分类号： A23L3/3463 , A23L3/3472 , A23L3/3526 , A23L3/3571 , C07K14/195 , C07K14/335 , C12N1/19 , C12N1/21 , C12N15/09 , C12N15/31 , C12N15/74 , C12P21/00 , C12P21/02 , C12R1/01 , A61K45/00 , A61K38/16 , C12N1/20
CPC分类号： C07K14/335 , A23L3/3472 , A23L3/3526 , A23L3/3571
摘要： The invention concerns an isolated polypeptide which is a bacteriocin called Sakacin G derived from Lactobacillus sakei 2512. The invention also concerns a nucleic acid molecule encoding for said bacteriocin and the use of said polypeptide as an active agent against pathogenic and undesirable flora in the preparation of food products.
摘要翻译：本发明涉及一种分离的多肽，其是称为由赖氨酸乳杆菌2512得到的称为Sakacin G的细菌素。本发明还涉及编码所述细菌素的核酸分子，以及所述多肽作为抗病原体和不良菌群的活性剂在制备食物产品。

52. 发明申请

US20050227357A1 Recombinant Penicillium funiculosum for homologous and heterologous protein production 审中-公开
标题翻译：重组Penicillium funiculosum用于同源和异源蛋白质生产
公开(公告)号：US20050227357A1
公开(公告)日：2005-10-13
申请号：US10947168
申请日：2004-09-23
申请人： Ralph Bohlmann , Nigel Belshaw , David Archer , Marcos Alcocer , Neville Fish , Jerome Pierrard , Carole Guitton
发明人： Ralph Bohlmann , Nigel Belshaw , David Archer , Marcos Alcocer , Neville Fish , Jerome Pierrard , Carole Guitton
IPC分类号： C12N1/16 , C12N9/24 , C12N9/64 , C12N15/74 , C12N15/80
CPC分类号： C12N9/248 , C07K2319/036 , C12N9/2402 , C12N9/2437 , C12N9/2442 , C12N9/6413 , C12N15/80
摘要： The present invention relates to a recombinant P. funiculosum strain for the production of homologous and heterologous proteins, and a transformation method for obtaining such recombinant P. funiculosum. Expression cassettes designed with genetic regulatory elements functional in P. funiculosum such as promoters, terminators and signal peptide encoding sequences are also encompassed by the present invention.
摘要翻译：本发明涉及用于产生同源和异源蛋白质的重组真菌菌株，以及用于获得这种重组真菌的转化方法。设计具有在真菌例如启动子，终止子和信号肽编码序列中功能的遗传调控元件的表达盒也包括在本发明中。

53. 发明申请

US20050123689A1 Use of a crosslinkable silicone invert emulsion for producing breathable coatings 审中-公开
标题翻译：使用可交联的硅氧烷反相乳液生产透气涂料
公开(公告)号：US20050123689A1
公开(公告)日：2005-06-09
申请号：US10503726
申请日：2003-02-07
申请人： Paul Branlard , Martial Deruelle , Yves Giraud , Nadia Martin
发明人： Paul Branlard , Martial Deruelle , Yves Giraud , Nadia Martin
IPC分类号： D06M11/79 , D06M13/513 , D06M15/643 , D06M15/65 , D06N3/12 , C08J7/04
CPC分类号： C09D183/04 , D06M15/643 , D06M15/65 , D06N3/128 , Y10T428/31663
摘要： The invention relates to the general field of silicone coating on various pliable supports, for example textiles, made of synthetic polymers (polyamide, polyester, etc.). An aim of the invention is to propose an effective process for producing coatings that are waterproof and permeable to moisture vapour, on pliable supports, this process allowing an improvement in the moisture vapour-permeability of the silicones while at the same time conserving the waterproofness. The process according to the invention which achieves this aim consists essentially in coating one of the faces of the support with a film formed by a water-in-oil inverse silicone emulsion comprising a continuous oily silicone phase φs, which can be crosslinked into an elastomer and which comprises a polyorganosiloxane (POS) A that is crosslinkable by polyaddition, by polycondensation, by cationic means or by free-radical means; optionally a crosslinking organosilicic compound B; optionally at least one catalyst C, an aqueous phase φa, a stabilizer, and in seeing to it that the silicone phase φs crosslinks and that removal of water occurs. The invention also relates to pliable supports made of polyamide or polyester, that are waterproof and permeable to moisture vapour, obtained by using a water-in-oil inverse silicone emulsion.
摘要翻译：本发明涉及在合成聚合物（聚酰胺，聚酯等）制成的各种柔韧载体上的硅酮涂层的一般领域，例如纺织品。本发明的目的是提出一种在柔韧的支撑物上生产防水和透湿的涂层的有效方法，该方法允许提高硅氧烷的透湿度，同时保持防水性。实现该目的的根据本发明的方法主要在于用由油包水反相硅氧烷乳液形成的膜涂覆载体的一个表面，所述油包水反相硅氧烷乳液包含连续的油性硅氧烷相phis，其可交联成弹性体并且其包含通过加聚可交联的聚有机硅氧烷（POS）A，通过缩聚，通过阳离子手段或通过自由基手段进行交联; 任选交联的有机硅化合物B; 任选地至少一种催化剂C，水相phia，稳定剂，并且认为有机硅相交联并发生水的除去。本发明还涉及通过使用油包水反相硅氧烷乳液获得的由聚酰胺或聚酯制成的柔性支撑体，其是防水的并且是透湿的。

54. 发明授权

US06881869B1 Method for preparing substituted mixed alkynyl ethers 失效
标题翻译：制备取代的混合炔基醚的方法
公开(公告)号：US06881869B1
公开(公告)日：2005-04-19
申请号：US10088455
申请日：2000-09-29
申请人： Roland Jacquot
发明人： Roland Jacquot
IPC分类号： C07B61/00 , C07C41/30 , C07C43/166 , C07C43/215 , C07C41/00
CPC分类号： C07C41/30 , C07C43/215
摘要： The present invention relates to a process for preparing mixed substituted alkynyl ethers. More particularly, the invention concerns the preparation of mixed ethers derived from a benzyl type alcohol and a substituted alkynyl alcohol. The process of the invention for preparing a benzyl/substituted alkynyl type mixed ether is prepared from a benzyl/alkynyl type mixed ether with a hydrogen atom on the triple bond is characterized in that it consists of reacting a mixed ether derived from a benzyl type alcohol and an alkynyl alcohol with a hydrogen atom on the triple bond with an alkylation agent, in the presence of an anionisation agent.
摘要翻译：本发明涉及一种制备混合取代炔基醚的方法。更具体地，本发明涉及由苄基型醇和取代的炔基醇制备的混合醚。制备苄基/取代的炔基型混合醚的本发明方法由三价键上的氢原子的苄基/炔基型混合醚制备，其特征在于其由衍生自苄基型醇的混合醚和在烷基化试剂的三键上具有氢原子的炔基醇，在阴离子化剂存在下。

55. 发明申请

US20050074386A1 Low water uptake silicas 有权
标题翻译：低吸水二氧化硅
公开(公告)号：US20050074386A1
公开(公告)日：2005-04-07
申请号：US10500107
申请日：2002-12-24
申请人： Remi Valero , Yvonick Chevallier
发明人： Remi Valero , Yvonick Chevallier
IPC分类号： A61K47/04 , A23L29/294 , C01B33/193 , C08K3/36 , C01B33/12
CPC分类号： C01B33/193 , C01P2006/12 , C01P2006/80 , C01P2006/82 , C08K3/36 , C08L83/04
摘要： The invention concerns a method for preparing low water uptake precipitated silicas, comprising successive steps which consist in: (a) producing an initial starter including a silicate, the silicate concentration in said starter, expressed in SiO2 equivalent, being less than 15 g/L; (b) bringing the medium pH to a value ranging between 7 and 8 by adding an acidifying agent, (c) in the resulting medium, simultaneously adding a silicate and an acidifying agent the respective amounts of silicate and acidifying agent added in time being specifically such that, during the entire addition (1) the reaction medium pH stays between 7 and 8, and (ii) the silicon concentration in the medium, expressed in SiO2 equivalent, stays below 35 g/L; (d) adding an acidifying agent in the medium resulting from step (c), so as to bring the medium to a pH ranging between 3 and 6.5; and (e) filtering the resulting aqueous silica dispersion, then drying the filter cake obtained at the end of the filtering step. The invention also concerns low water uptake silicas obtained by said method and their use, in particular for reinforcing silicones or polymer or elastomer matrices.
摘要翻译：本发明涉及一种制备低吸水沉淀二氧化硅的方法，包括连续步骤，其包括：（a）产生包含硅酸盐的初始起始物，所述起始物中的硅酸盐浓度以SiO 2当量表示，小于15g / L ; （b）通过添加酸化剂使介质pH值达到7〜8，（c）在得到的培养基中，同时加入硅酸盐和酸化剂，分别加入相应量的硅酸盐和酸化剂使得在整个添加（1）期间，反应介质pH保持在7和8之间，和（ii）以SiO 2当量表示的介质中的硅浓度保持在35g / L以下; （d）在由步骤（c）得到的培养基中加入酸化剂，以使培养基达到3至6.5的pH; 和（e）过滤所得的二氧化硅水溶液，然后干燥在过滤步骤结束时获得的滤饼。本发明还涉及通过所述方法获得的低吸水二氧化硅及其用途，特别是用于增强硅氧烷或聚合物或弹性体基质。

56. 发明授权

US06875516B2 Silicone composition crosslinkable by dehydrogenating condensation in the presence of a metal catalyst 失效
标题翻译：有机硅组合物可通过在金属催化剂存在下脱氢缩合而交联
公开(公告)号：US06875516B2
公开(公告)日：2005-04-05
申请号：US10124270
申请日：2002-04-18
申请人： Jean-Paul Benayoun , Delphine Blanc-Magnard , Gérard Mignani , Christian Mirou
发明人： Jean-Paul Benayoun , Delphine Blanc-Magnard , Gérard Mignani , Christian Mirou
IPC分类号： B32B9/04 , B32B25/20 , C08G77/08
CPC分类号： C08J9/02 , C08G77/045 , C08G77/12 , C08G77/16 , C08G2101/00 , C08J2201/024 , C08J2383/04 , C08J2383/08 , C08K5/50 , C08L83/04 , C09D183/08 , Y10T428/24504 , Y10T428/249954 , Y10T428/249958 , Y10T428/31663 , C08L83/00
摘要： An ≡SiH/≡SiOH silicone composition polymerizable/crosslinkable by dehydrogenating condensation in the presence of a catalyst judiciously selected to achieve at least one of the following: kinetics, concentration/efficiency ratio of the catalyst, cost, lowering of the catalyst activation temperature (room temperature), control of the release of gaseous hydrogen and the quality of the polymerized product and the crosslinked network, and finally limitation of the secondary reactions. This composition includes: —A— at least one ≡SiH POS; —B— at least one ≡SiOH POS; —C— at least one metal catalyst selected from the group of organometallic complexes including at least one of the following metals: Ir, Ru, Mn; —D— optionally at least one crosslinking inhibitor; —E— optionally at least one POS resin; and —F— optionally at least one filler. Also disclosed is the catalyst —C— and processes which involve crosslinking of silicone by dehydrogenating condensation (non-stick coating on paper).
摘要翻译： An = SiH / = SiOH硅氧烷组合物，其通过在催化剂存在下通过脱气缩合而可聚合/交联，所述催化剂明智地选择以实现以下至少一种：动力学，催化剂的浓度/效率比，成本，催化剂活化温度的降低室温），控制气态氢的释放以及聚合产物和交联网络的质量，最后限制二次反应。该组合物包括：-A-至少一个= SiH POS; -B-至少一个= SiOH POS; -C-至少一种金属催化剂，其选自包括以下金属中的至少一种的有机金属络合物：Ir， Ru，Mn; -D-任选至少一种交联抑制剂; -E-任选至少一种POS树脂; 和-F-任选的至少一种填料。还公开了催化剂-C-和涉及通过脱氢冷凝（纸上不粘涂层）使硅氧烷交联的方法。

57. 发明申请

US20050059752A1 Stable, cationically polymerizable/crosslinkable dental compositions having high filler contents 审中-公开
标题翻译：具有高填料含量的稳定的可阳离子聚合/可交联牙科组合物
公开(公告)号：US20050059752A1
公开(公告)日：2005-03-17
申请号：US10933537
申请日：2004-09-03
申请人： Jean-Marc Frances
发明人： Jean-Marc Frances
IPC分类号： A61K6/083 , A61K6/093 , A61K6/08
CPC分类号： A61K6/0052 , A61K6/093 , Y10S522/908 , C08L83/12
摘要： Stable, highly filled cationic dental compositions useful for the production of dental prostheses and dental restoration materials contain: (1) at least one compound which is reactive cationically when activated, advantageously at least one UV-and cationically reactive oxirane-functionalized silicone; (2) at least one dental filler, advantageously SiO2; (3) at least one organic polymer or copolymer dispersant having an amine index less than or equal to 100 mg of potassium hydroxide per gram of dispersant, advantageously a polyurethane/acrylate copolymer or alkylammonium salt thereof; (4) at least one cationic photoinitiator, advantageously iodonium borate; and (5) optionally, at least one photosensitizer.
摘要翻译：用于生产牙科假体和牙科修复材料的稳定，高度填充的阳离子牙科组合物包含：（1）至少一种当被活化时反应阳离子的化合物，有利的是至少一种UV-阳离子反应性环氧乙烷官能化硅酮; （2）至少一种牙科填料，有利地是SiO 2; （3）至少一种有机聚合物或共聚物分散剂，其胺指数小于或等于100mg氢氧化钾/克分散剂，有利地是聚氨酯/丙烯酸酯共聚物或其烷基铵盐; （4）至少一种阳离子光引发剂，优选硼酸铵; 和（5）任选的至少一种光敏剂。

58. 发明授权

US06858696B2 Method for synthesis of hybrid silicon and organic copolymers by controlled free radical polymerization 有权
标题翻译：通过控制自由基聚合合成杂化硅和有机共聚物的方法
公开(公告)号：US06858696B2
公开(公告)日：2005-02-22
申请号：US10333882
申请日：2001-07-25
申请人： Mathias Destarac , Gérard Mignani , Samir Zard , Béatrice Sire , Chakib Kalai
发明人： Mathias Destarac , Gérard Mignani , Samir Zard , Béatrice Sire , Chakib Kalai
IPC分类号： C08F2/38 , C08F283/12 , C08F290/00 , C08F290/06 , C08F293/00 , C08G77/392 , C08G77/442 , C08L51/08 , C08G77/06
CPC分类号： C08F283/12 , C08F2/38 , C08F290/00 , C08F290/068 , C08F293/005 , C08G77/392 , C08G77/442 , C08L51/085
摘要： The invention concerns a method for preparing by thermal activation of hybrid silicone and organic polymers comprising the motifs RxUySiO[4−(x+y)]/2 (I) wherein: x is equal to 0, 1, 2 or 3, y is equal to 0, 1, 2 or 3 with 2≦(x+y)≦3 and y is different from 0 for at least one of the hybrid copolymer motifs; and the symbols U, identical or different, represent organic polymer units.
摘要翻译：本发明涉及一种通过热活化制备杂化硅氧烷和有机聚合物的方法，该聚合物包含图案RxUySiO [4-（x + y）] / 2（I），其中：x等于0,1,2或3，y为等于0,1,2或3，其中2 <=（x + y）<= 3，并且对于至少一种杂化共聚物基序，y不同于0; 符号U相同或不同，表示有机聚合物单元。

59. 发明授权

US06858668B2 Method for masking polyisocyanates in emulsion 失效
标题翻译：在乳液中掩蔽多异氰酸酯的方法
公开(公告)号：US06858668B2
公开(公告)日：2005-02-22
申请号：US09486343
申请日：1998-08-27
申请人： Jean-Marie Bernard , Jean-Pierre Corbet , Minou Nabavi , Philippe Galy-Jammou , Denis Revelant
发明人： Jean-Marie Bernard , Jean-Pierre Corbet , Minou Nabavi , Philippe Galy-Jammou , Denis Revelant
IPC分类号： C08G18/70 , C08G18/80 , C08J3/00 , B01J10/00 , C08G18/81 , C08K3/20 , C08L75/00
CPC分类号： C08G18/8077 , C08G18/706 , C08G18/8083 , C08G18/8096 , Y10T428/31551
摘要： This invention relates to a process for the preparation of aqueous emulsions of blocked (poly)isocyanates, this process comprising the steps consisting successively in: a) placing an isocyanate composition containing free isocyanate functions in contact with at least one blocking agent A in the presence of a surfactant B and an aqueous phase, the said isocyanate composition being added gradually to a stock containing at least some of the aqueous phase and at least some of the blocking agent; and optionally, b) subjecting the mixture obtained to a shear (speed gradient) of greater than 1000 s−1, preferably greater than 20,000 s−1 and less than 1,000,000 s−1, preferably less than 200,000 s−1, and c) repeating step b), optionally after step a) has been repeated, until a stable emulsion is obtained whose particles have a Sauter diameter of greater than 0.1 μm, preferably 0.2 μm, and less than 5 μm, preferably less than 2 μm, and a dispersion width of less than 5 μm.
摘要翻译：本发明涉及一种制备封闭的（多）异氰酸酯的水性乳液的方法，该方法包括以下步骤：连续地在以下步骤中：a）将含有游离异氰酸酯官能团的异氰酸酯组合物与至少一种封闭剂A接触，的表面活性剂B和水相，将所述异氰酸酯组合物逐渐加入到含有至少一些水相和至少一些封闭剂的浆料中;以及任选地，b）使获得的混合物经受剪切（速度梯度）大于1000s -1，优选大于20,000s -1且小于1,000,000s -1，优选小于200,000s -1，和c）重复步骤b），任选地在步骤a）已经重复，直到得到其颗粒的沙特直径大于0.1μm，优选0.2μm，小于5μm，优选小于2μm，分散宽度小于5μm的稳定乳液。

60. 发明授权

US06855518B2 Anti-listeria bacteriocin 有权
标题翻译：抗李斯特菌细菌素
公开(公告)号：US06855518B2
公开(公告)日：2005-02-15
申请号：US10296723
申请日：2001-05-28
申请人： Jean-Marie Berjeaud , Christophe Fremaux , Yves Cenatiempo , Laurence Simon
发明人： Jean-Marie Berjeaud , Christophe Fremaux , Yves Cenatiempo , Laurence Simon
IPC分类号： A23L3/3463 , A23L3/3472 , A23L3/3526 , A23L3/3571 , C07K14/195 , C07K14/335 , C12N1/19 , C12N1/21 , C12N15/09 , C12N15/31 , C12N15/74 , C12P21/00 , C12P21/02 , C12R1/01 , C12P21/06 , C07H17/00 , C07K14/00
CPC分类号： C07K14/335 , A23L3/3472 , A23L3/3526 , A23L3/3571
摘要： The invention concerns an isolated polypeptide which is a bacteriocin called Sakacin G derived from Lactobacillus sakei 2512. The invention also concerns a nucleic acid molecule encoding for said bacteriocin and the use of said polypeptide as an active agent against pathogenic and undesirable flora in the preparation of food products.
摘要翻译：本发明涉及一种分离的多肽，其是称为由赖氨酸乳杆菌2512得到的称为Sakacin G的细菌素。本发明还涉及编码所述细菌素的核酸分子，以及所述多肽作为抗病原体和不良菌群的活性剂在制备食物产品。

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