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51. 发明授权

US08747682B2 Pattern formation method and method for manufacturing semiconductor device 失效
标题翻译：图案形成方法和制造半导体器件的方法
公开(公告)号：US08747682B2
公开(公告)日：2014-06-10
申请号：US12849599
申请日：2010-08-03
申请人： Kentaro Matsunaga , Tomoya Oori , Eishi Shiobara , Yukiko Sato , Yoshihisa Kawamura
发明人： Kentaro Matsunaga , Tomoya Oori , Eishi Shiobara , Yukiko Sato , Yoshihisa Kawamura
IPC分类号： C03C15/00 , C03C25/68 , C23F1/00 , H01B13/00 , B44C1/22
CPC分类号： H01L21/0337 , B81C1/00031 , B81C2201/0149
摘要： According to one embodiment, a pattern formation method is disclosed. The method includes forming a plurality of regions on a foundation and the plurality of the regions correspond to different pattern sizes. The method includes separating each of a plurality of block copolymers from another one of the plurality of the block copolymers and segregating the each of the plurality of the block copolymers into a corresponding one of the regions. The method includes performing a phase separation of the each of the block copolymers of each of the regions. The method includes selectively removing a designated phase of each of the phase-separated block copolymers to form a pattern of the each of the block copolymers and the pattern has a different pattern size for the each of the regions.
摘要翻译：根据一个实施例，公开了图案形成方法。该方法包括在基础上形成多个区域，并且多个区域对应于不同的图案尺寸。该方法包括从多个嵌段共聚物中的另一个嵌段共聚物中分离多个嵌段共聚物，并将多个嵌段共聚物中的每一个分离成相应的一个区域。该方法包括进行每个区域的每个嵌段共聚物的相分离。该方法包括选择性地除去每个相分离的嵌段共聚物的指定相以形成每个嵌段共聚物的图案，并且该图案对于每个区域具有不同的图案尺寸。

52. 发明授权

US08597873B2 Method for pattern formation 有权
标题翻译：图案形成方法
公开(公告)号：US08597873B2
公开(公告)日：2013-12-03
申请号：US13592635
申请日：2012-08-23
申请人： Yoshihisa Kawamura
发明人： Yoshihisa Kawamura
IPC分类号： G03F7/26
CPC分类号： H01L21/0271 , B82Y10/00 , B82Y40/00 , G03F7/0002 , G03F7/0035 , G03F7/0042 , G03F7/0043 , G03F7/038 , G03F7/0755 , G03F7/0757 , H01L21/31144 , H01L27/1052
摘要： According to one embodiment, a method for pattern formation comprises forming a first pattern on a first region of a processed film, forming a reverse material film, having a photosensitive compound, on the processed film so that the reverse material film covers the first pattern, exposing and developing the reverse material film and processing the reverse material film into a second pattern in a second region different from the first region on the processed film, applying etch-back, after exposing and developing the reverse material film, to the reverse material film to expose an upper surface of the first pattern and processing the reverse material film into a third pattern in the first region, and etching the processed film using the second pattern and the third pattern as masks.
摘要翻译：根据一个实施例，一种用于图案形成的方法包括在处理膜的第一区域上形成第一图案，在加工膜上形成具有感光性化合物的反向材料膜，使得反向材料膜覆盖第一图案，曝光和显影反向材料膜并将反相材料膜在与处理膜上的第一区域不同的第二区域中处理成第二图案，在将反向材料膜曝光和显影之后施加回蚀刻到反向材料膜以暴露第一图案的上表面，并将反向材料膜处理成第一区域中的第三图案，并且使用第二图案和第三图案作为掩模蚀刻处理的膜。

53. 发明申请

US20120242002A1 TEMPLATE, SURFACE PROCESSING METHOD OF TEMPLATE, SURFACE PROCESSING APPARATUS OF TEMPLATE, AND PATTERN FORMATION METHOD 审中-公开
标题翻译：模板，模板表面处理方法，模板表面处理装置和图案形成方法
公开(公告)号：US20120242002A1
公开(公告)日：2012-09-27
申请号：US13412019
申请日：2012-03-05
申请人： Masako KOBAYASHI , Hideaki Hirabayashi , Yoshihisa Kawamura , Momoka Higa
发明人： Masako KOBAYASHI , Hideaki Hirabayashi , Yoshihisa Kawamura , Momoka Higa
IPC分类号： B29C59/02
CPC分类号： G03F7/0002 , B82Y10/00 , B82Y40/00
摘要： A template includes a transfer surface having an unevenness pattern. The template is configured to form a configuration in a surface of a resin to reflect the unevenness pattern. The resin is formed by filling a photocurable resin liquid into a recess of the unevenness pattern in a state prior to using light to cure the photocurable resin liquid and by using the light to cure the photocurable resin liquid. The template includes a base member and a surface layer. The base member includes a major surface having an unevenness. The surface layer covers the unevenness of the base member, and is used to form the unevenness pattern to reflect a configuration of the unevenness. A contact angle between the surface layer and the photocurable resin liquid in the state prior to using the light to cure the photocurable resin liquid is not more than 30 degrees.
摘要翻译：模板包括具有凹凸图案的转印面。模板被配置为在树脂的表面中形成反射不平坦图案的构造。在使用光固化光固化性树脂液体之前的状态下，通过使光固化光固化树脂液体的状态，将光固化树脂液体填充到凹凸图案的凹部中而形成树脂。模板包括基底构件和表面层。基部构件包括具有凹凸的主表面。表面层覆盖基体的凹凸，用于形成凹凸图案，以反映凹凸的形状。在使用光固化光固化性树脂液体之前的状态下，表面层与光固化性树脂液体之间的接触角不大于30度。

54. 发明申请

US20070279152A1 THIN FILM PIEZOELECTRIC RESONATOR AND METHOD OF MANUFACTURING SAME 审中-公开
标题翻译：薄膜压电谐振器及其制造方法
公开(公告)号：US20070279152A1
公开(公告)日：2007-12-06
申请号：US11756958
申请日：2007-06-01
申请人： Yoshihisa Kawamura
发明人： Yoshihisa Kawamura
IPC分类号： H03H9/58
CPC分类号： H03H9/0095 , H03H3/04 , H03H9/105 , H03H9/564 , H03H9/566
摘要： A thin film piezoelectric resonator includes: a substrate having an opening portion which passes through from a top surface to a bottom surface of the substrate, and an aperture which is provided distant from the opening portion; a resonance section having a lower electrode provided on the opening portion of the substrate, a piezoelectric film provided on the lower electrode and an upper electrode opposed to the lower electrode across the piezoelectric film; a cover layer; and a resin layer provided on the cover layer. The cover layer covers the resonance section through a cavity which is formed above the upper electrode. The cavity is connected to the aperture.
摘要翻译：薄膜压电谐振器包括：具有从基板的顶表面通过的开口部分的基板和远离开口部分设置的开口; 具有设置在基板的开口部的下部电极的共振部，设置在下部电极上的压电膜和跨越压电膜的与下部电极相对的上部电极; 覆盖层; 以及设置在覆盖层上的树脂层。覆盖层通过形成在上电极上方的空腔覆盖共振部分。空腔连接到孔。

55. 再颁专利

USRE39352E1 Creatine amidinohydrolase, production thereof and use thereof 有权
标题翻译：肌酸脒基水解酶，其制备及其用途
公开(公告)号：USRE39352E1
公开(公告)日：2006-10-17
申请号：US10807228
申请日：2004-03-23
申请人： Atsushi Sogabe , Takashi Hattori , Yoshiaki Nishiya , Yoshihisa Kawamura
发明人： Atsushi Sogabe , Takashi Hattori , Yoshiaki Nishiya , Yoshihisa Kawamura
IPC分类号： C12N9/78 , C12N15/01 , C12N1/21 , C12Q1/34 , C07H21/04
CPC分类号： G01N33/52 , C12Q1/34 , G01N2333/978 , Y10S435/829
摘要： A creatine amidinohydrolase having the following physicochemical properties: Action: catalyzing the following reaction; creatine+H2O→sarcosine+urea Optimum temperature: about 40-50° C. Optimum pH: pH about 8.0-9.0 Heat stability: not more than 50° C. (pH 7.5, 30 min) Km value for creatine in a coupling assay using a sarcosine oxidase and a peroxidase: about 3.5-10.00 mM Molecular weight: about 43,000 (SDS-PAGE) Isoelectric point: 3.5 4.5, a method for producing said enzyme, comprising culture of microorganism producing said enzyme, a method for the determination of creatine or creatinine in a sample using said enzyme, and a reagent therefor.
摘要翻译：具有以下物理化学性质的肌酸脒基水解酶：作用：催化以下反应; 肌酸+ H 2→肌氨酸+尿素最佳温度：约40-50℃最佳pH：pH约8.0-9.0热稳定性：不超过50℃（pH7.5,30 min）在使用肌氨酸氧化酶和过氧化物酶的偶联试验中，肌酸的Km值为约3.5-10.00mM分子量：约43,000（SDS-PAGE）等电点：<β删除开始ID =“DEL-S-00001” date =“20061017”？> 3.5 <？delete-end id =“DEL-S-00001”？> <？insert-start id =“INS-S-00001”date =“20061017”？> 4.5 <？insert- end id =“INS-S-00001”→>，所述酶的制备方法包括培养产生所述酶的微生物，使用所述酶测定样品中的肌酸或肌酸酐的方法及其试剂。

56. 发明授权

US07048915B2 Composition for cell-free protein synthesis 失效
公开(公告)号：US07048915B2
公开(公告)日：2006-05-23
申请号：US10124953
申请日：2002-04-18
申请人： Toshihiro Kuroita , Bunsei Kawakami , Yoshihisa Kawamura , Shigemichi Nishikawa , Yaeta Endo
发明人： Toshihiro Kuroita , Bunsei Kawakami , Yoshihisa Kawamura , Shigemichi Nishikawa , Yaeta Endo
IPC分类号： A61K33/00 , A61K35/78 , C12P21/06 , A01N65/00
CPC分类号： C12P21/02
摘要： The present invention provides a composition for cell-free protein synthesis, which is superior in storage stability in a freeze-dried state, more particularly a freeze-dryable or freeze-dried composition for cell-free protein synthesis, which contains a cell extract for cell-free protein synthesis and inositol, and a freeze-dryable or freeze-dried composition for cell-free protein synthesis containing a cell extract for cell-free protein synthesis, and a deliquescent material in a proportion of not more than 0.01 part by weight per part by weight of a protein in the composition; and a composition for cell-free protein synthesis superior in storage stability in a frozen state, more particularly a freezable or frozen composition for cell-free protein synthesis, containing a cell extract for cell-free protein synthesis and polyhydric alcohol.

57. 发明申请

US20050069887A1 Dna synthesis promoters dna polymerase-associated factors and utilization thereof 有权
标题翻译： Dna合成启动子dna聚合酶相关因子及其利用
公开(公告)号：US20050069887A1
公开(公告)日：2005-03-31
申请号：US10495581
申请日：2002-11-14
申请人： Masao Kitabayashi , Toshihiro Kuroita , Yoshikazu Ishida , Hideyuki Komatsubara , Yoshiaki Nishiya , Masanori Oka , Yoshihisa Kawamura , Tadayuki Imanaka
发明人： Masao Kitabayashi , Toshihiro Kuroita , Yoshikazu Ishida , Hideyuki Komatsubara , Yoshiaki Nishiya , Masanori Oka , Yoshihisa Kawamura , Tadayuki Imanaka
IPC分类号： C07K14/195 , C12N9/12 , C12P19/34 , C12Q1/68
CPC分类号： C07K14/195 , C12N9/1252 , C12Q1/6846 , C12Q2527/125 , C12Q2521/101
摘要： A composition for enhancing synthesis of DNA comprising an anion-supplying substance that is effective in promoting DNA synthesis in enzymatic DNA synthesis reactions, in particular a salt of a dicarboxylic acid. Further enhanced DNA synthesis promoting effects can be achieved by using, together with the anion-supplying substance, at least one compound selected from the group consisting of dimethylsulfoxide and compounds represented by the following formula (1): R2—CH2—NR1xHy (1) wherein R1 is an alkyl group having 1 to 3 carbon atoms, R2 is a substituent selected from the group consisting of the following (a) and (b): (a) oxygen and (b) radicals represented by the formula wherein R4 is methyl, hydrogen or forms a pyrrolidine ring when combined with R1, R5 is —CO2H or —SO3H, and n is an integer from 0 to 2, x is an integer from 1 to 3 and y is an integer from 0 to 2, provided that x plus y equals 3. The present invention further provides a thermostable DNA polymerase-related factor derived from Thermococcus species, which has an activity to promote the DNA synthesis activity of DNA polymerase or bind to DNA polymerase.
摘要翻译：一种用于增强DNA合成的组合物，其包含在促进DNA合成反应中有效促进DNA合成的阴离子供给物质，特别是二羧酸的盐。通过与阴离子供给物质一起使用至少一种选自二甲基亚砜和下式（1）表示的化合物的化合物，可以实现进一步增强的DNA合成促进效果：R 2 -CH 2 -NR <1> xHy（1）其中R 1是具有1至3个碳原子的烷基，R 2是选自以下（a）和（b）的取代基：（a）氧和（b）由下式表示的基团其中R 4是甲基，氢或当与R 1一起形成吡咯烷环时，R 5是-CO 2 H或-SO 3 H，n是0至 2，x是1至3的整数，y是0至2的整数，条件是x加y等于3.本发明还提供了源自Thermococcus物种的热稳定DNA聚合酶相关因子，其具有活性促进DNA聚合酶的DNA合成活性或与DNA聚合酶结合。

58. 发明授权

US06638725B2 Method for assaying receptor binding property and reagent for the assay 失效
标题翻译：用于测定受体结合性质的方法和用于测定的试剂
公开(公告)号：US06638725B2
公开(公告)日：2003-10-28
申请号：US09490053
申请日：2000-01-24
申请人： Yoshihiro Soya , Shigeaki Nishii , Kazuhiro Matsui , Takuya Ishibashi , Yoshihisa Kawamura
发明人： Yoshihiro Soya , Shigeaki Nishii , Kazuhiro Matsui , Takuya Ishibashi , Yoshihisa Kawamura
IPC分类号： G01N3353
CPC分类号： G01N33/743 , G01N33/53 , G01N33/54306 , G01N2333/723 , Y10S530/812 , Y10S530/816 , Y10S530/827
摘要： The present invention provides a method capable of simultaneous processing of plural test samples for the receptor binding property of a chemical substance, which does not require immobilization of the receptor or a special device, and a reagent to be used for this method. That is a method for assaying the receptor binding property of an assay target substance is provided, the method comprising the steps of (a) competitively reacting a known concentration of a ligand and the assay target substance with a known concentration of the receptor in a solution, (b) measuring, without physically removing the ligand bound with the receptor prior to the assay, the amount of a free ligand in the solution using one or more antibodies against the ligand, and (c) determining the receptor binding property of the assay target substance using the amount of the free ligand as an index.
摘要翻译：本发明提供一种能够同时处理多个测试样品用于不需要固定受体或特殊装置的化学物质的受体结合特性的试剂和用于该方法的试剂。这是一种用于测定测定目标物质的受体结合性质的方法，该方法包括以下步骤：（a）将已知浓度的配体和测定目标物质与已知浓度的受体在溶液中竞争性地反应，（b）在测定前物理除去与受体结合的配体，测量溶液中使用一种或多种针对配体的抗体的游离配体的量，以及（c）测定该测定的受体结合性质使用游离配体的量作为指标的目标物质。

59. 发明授权

US6054301A Methods of amplification using a thermostable DNA polymerase from the hyperthermophilic archaeon strain KOD1 and reagent kit therefor 失效
标题翻译：使用来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶的扩增方法及其试剂盒
公开(公告)号：US6054301A
公开(公告)日：2000-04-25
申请号：US656005
申请日：1996-05-24
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N15/09 , C12N1/21 , C12N9/12 , C12N15/54 , C12P21/02 , C12P21/04 , C12Q1/68 , C12R1/01 , C12R1/19 , G01N33/53 , G01N33/566 , C12P19/34 , C07K15/00
CPC分类号： C12Q1/686 , C12N9/1252
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

60. 发明授权

US6033859A Thermostable DNA polymerase from a hyperthermophilic archaeon strain KOD1 失效
标题翻译：来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶
公开(公告)号：US6033859A
公开(公告)日：2000-03-07
申请号：US73354
申请日：1998-05-06
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N9/12 , C12Q1/68 , C12P19/34 , C07K14/00 , C12N9/00
CPC分类号： C12N9/1252 , C12Q1/686
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

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