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51. 发明申请

US20160291458A1 METHOD INTEGRATING TARGET OPTIMIZATION AND OPTICAL PROXIMITY CORRECTION 审中-公开
标题翻译：方法集成目标优化和光学近似校正
公开(公告)号：US20160291458A1
公开(公告)日：2016-10-06
申请号：US14753192
申请日：2015-06-29
申请人： Daquan He , Fang Wei , Jun Zhu , Yukun Lv , Xusheng Zhang
发明人： Daquan He , Fang Wei , Jun Zhu , Yukun Lv , Xusheng Zhang
IPC分类号： G03F1/36 , G06F17/50
CPC分类号： G03F1/36
摘要： A method integrating target optimization and optical proximity correction including: fragmenting sides of a target pattern in the metal layer to form a plurality of fragments; simulating the target pattern and calculating image log slope of each fragment; calculating a target pattern optimal parameter for each fragment which is a product of three parameters including the image log slope, overlap ratio of the target pattern and a via pattern in a via layer, and critical dimension; optimizing the target pattern based on the target pattern optimal parameter; preforming optical proximity correction to the optimized target pattern; determining whether the corrected target pattern meets requirements; if yes, ending the target optimization and optical proximity correction; otherwise, using the corrected target pattern as a current target pattern and iterate from the step of simulating the target pattern and calculating image log slope of each fragment.
摘要翻译：一种集成目标优化和光学邻近校正的方法，包括：金属层中的目标图案的碎裂边以形成多个碎片; 模拟目标模式并计算每个片段的图像对数斜率; 计算每个片段的目标图案最优参数，该三个参数的乘积包括图像对数斜率，目标图案的重叠率和通孔层中的通孔图案以及临界尺寸; 基于目标模式优化参数优化目标模式; 对优化的目标图案进行光学邻近校正; 确定校正的目标模式是否满足要求; 如果是，结束目标优化和光学邻近校正; 否则，使用校正的目标图案作为当前目标图案，并且从模拟目标图案的步骤并且计算每个片段的图像对数斜率来迭代。

52. 发明申请

US20120101392A1 OPTIMIZATION OF ARRHYTHMIA DETECTION BASED ON PATIENT ACTIVITY 审中-公开
标题翻译：基于患者活动的ARRHYTHMIA检测优化
公开(公告)号：US20120101392A1
公开(公告)日：2012-04-26
申请号：US12912111
申请日：2010-10-26
申请人： Sourav K. Bhunia , Xusheng Zhang
发明人： Sourav K. Bhunia , Xusheng Zhang
IPC分类号： A61B5/0205
CPC分类号： A61N1/3621 , A61N1/36542 , A61N1/3702
摘要： An implantable medical device is configured to perform a method for detecting cardiac events by sensing a patient activity signal and determining a patient activity trend in response to the activity signal. A cardiac event detection threshold is set in response to the patient activity trend. The device senses a cardiac signal and detects a cardiac event in response to the cardiac signal and the detection threshold.
摘要翻译：可植入医疗装置被配置为通过感测患者活动信号并且响应于活动信号确定患者活动趋势来执行用于检测心脏事件的方法。响应于患者活动趋势设置心脏事件检测阈值。该装置感测心脏信号，并根据心脏信号和检测阈值检测心脏事件。

53. 发明授权

US08160684B2 Method and apparatus for detecting arrhythmias in a medical device 有权
标题翻译：用于检测医疗装置中的心律失常的方法和装置
公开(公告)号：US08160684B2
公开(公告)日：2012-04-17
申请号：US11380837
申请日：2006-04-28
申请人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang
发明人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang
IPC分类号： A61B5/0452 , A61N1/368
CPC分类号： A61N1/3987 , A61B5/04011 , A61B5/0422 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61B5/7221 , A61B5/7239 , A61N1/05 , A61N1/3621 , A61N1/3925 , A61N1/3956 , Y10S128/901 , Y10S128/902
摘要： A method of detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes forming a first sensing vector and a second sensing vector, and determining whether the sensing of cardiac signals along the first sensing vector and along the second sensing vector is corrupted by noise. If the cardiac signals sensed along both the first sensing vector and the second sensing vector are not corrupted by noise, a determination is made as to whether the cardiac signals sensed along the first sensing vector and along the second sensing vector are one of a first cardiac event and a second cardiac event. The determination of whether the cardiac signals sensed along the first sensing vector and along the second sensing vector are one of a first cardiac event and a second cardiac event is then confirmed.
摘要翻译：一种检测医疗装置中的心脏事件的方法，包括：感测来自形成第一感测向量和第二感测向量的多个电极的心脏信号，以及确定沿着第一感测向量并沿着第二感测的心脏信号的感测矢量被噪音破坏了。如果沿着第一感测向量和第二感测矢量两者感测的心脏信号不被噪声破坏，则确定沿着第一感测向量和沿着第二感测向量感测的心脏信号是否是第一心脏事件和第二次心脏事件。然后确定沿着第一感测向量和沿着第二感测向量感测的心脏信号是否是第一心脏事件和第二心脏事件之一的确定。

54. 发明授权

US08068901B2 Method and apparatus for adjusting a sensing parameter 有权
标题翻译：用于调整感测参数的方法和装置
公开(公告)号：US08068901B2
公开(公告)日：2011-11-29
申请号：US11742625
申请日：2007-05-01
申请人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
发明人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
IPC分类号： A61B5/0402
CPC分类号： A61N1/3704 , A61B5/0456 , A61B5/046 , A61B5/7239 , A61N1/3925
摘要： A method and apparatus of updating a sensing parameter in a medical device that includes sensing cardiac signals, determining intervals in response to the sensed cardiac signals, determining interval patterns associated with the determined intervals, and updating the sensing parameter in response to the determined interval patterns.
摘要翻译：一种更新医疗设备中的感测参数的方法和装置，包括感测心脏信号，响应于感测的心脏信号确定间隔，确定与所确定的间隔相关联的间隔模式，以及响应于所确定的间隔模式来更新感测参数。

55. 发明授权

US07937135B2 Method and apparatus for adjusting a sensing parameter 有权
标题翻译：用于调整感测参数的方法和装置
公开(公告)号：US07937135B2
公开(公告)日：2011-05-03
申请号：US11742628
申请日：2007-05-01
申请人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
发明人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
IPC分类号： A61B5/0402
CPC分类号： A61N1/3925 , A61N1/3704
摘要： A method and apparatus for determining oversensing in a medical device that includes sensing cardiac signals, determining an oversensing characteristic associated with cardiac signals sensed during a predetermined sensing window, identifying oversensing in response to the oversensing characteristic, determining, in response to oversensing being identified, an adjusting characteristic associated with cardiac signals sensed during the predetermined sensing window, and updating a sensing parameter in response to the determined adjusting characteristic.
摘要翻译：一种用于确定医疗装置中的过度感测的方法和装置，包括感测心脏信号，确定与在预定感测窗口期间感测到的心脏信号相关联的过度感应特征，响应于过敏特性识别过敏，响应于被识别的过冷而确定，与在预定感测窗口期间感测到的心脏信号相关联的调整特性，以及响应于确定的调整特性来更新感测参数。

56. 发明申请

US20080275519A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 有权
标题翻译：用于检测医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：US20080275519A1
公开(公告)日：2008-11-06
申请号：US11742618
申请日：2007-05-01
申请人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
发明人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
IPC分类号： A61N1/00
CPC分类号： A61N1/3925 , A61N1/3704
摘要： A method and apparatus for adjusting a sensing parameter in a medical device that includes a sensing electrode sensing cardiac signals, a processor to determine an adjusting characteristic associated with the cardiac signals sensed over a predetermined sensing window, and a control unit to update the sensing parameter in response to the determined adjusting characteristic.
摘要翻译：一种用于调整包括感测心脏信号的感测电极的医疗装置中的感测参数的方法和装置，用于确定与在预定感测窗口上感测到的心脏信号相关联的调整特性的处理器以及用于更新感测参数的控制单元响应于确定的调整特性。

57. 发明申请

US20080275516A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 有权
标题翻译：用于检测医疗器械中的脑膜炎的方法和装置
公开(公告)号：US20080275516A1
公开(公告)日：2008-11-06
申请号：US11742625
申请日：2007-05-01
申请人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
发明人： Raja N. Ghanem , Robert W. Stadler , Xusheng Zhang , Karen J. Kleckner , Paul G. Krause
IPC分类号： A61N1/00
CPC分类号： A61N1/3704 , A61B5/0456 , A61B5/046 , A61B5/7239 , A61N1/3925
摘要： A method and apparatus of updating a sensing parameter in a medical device that includes sensing cardiac signals, determining intervals in response to the sensed cardiac signals, determining interval patterns associated with the determined intervals, and updating the sensing parameter in response to the determined interval patterns.
摘要翻译：一种更新医疗设备中的感测参数的方法和装置，包括感测心脏信号，响应于感测的心脏信号确定间隔，确定与所确定的间隔相关联的间隔模式，以及响应于所确定的间隔模式来更新感测参数。

58. 发明申请

US20070239050A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 有权
标题翻译：用于检测医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：US20070239050A1
公开(公告)日：2007-10-11
申请号：US11380830
申请日：2006-04-28
申请人： Raja Ghanem , Robert Stadler , Xusheng Zhang
发明人： Raja Ghanem , Robert Stadler , Xusheng Zhang
IPC分类号： A61B5/04
CPC分类号： A61N1/3987 , A61B5/04011 , A61B5/0422 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61B5/7221 , A61B5/7239 , A61N1/05 , A61N1/3621 , A61N1/3925 , A61N1/3956 , Y10S128/901 , Y10S128/902
摘要： A method of detecting a cardiac event that includes sensing cardiac signals from a plurality of electrodes, determining rates of change of the sensed cardiac signals, and determining a range of the sensed cardiac signals. The sensed cardiac signals are detected as being associated with the cardiac event in response to the determined rates of change and the determined range.
摘要翻译：一种检测心脏事件的方法，其包括感测来自多个电极的心脏信号，确定所感测的心脏信号的变化速率，以及确定感测的心脏信号的范围。根据所确定的变化速率和所确定的范围，将所感测到的心脏信号检测为与心脏事件相关联。

59. 发明申请

US20070239046A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A MEDICAL DEVICE 有权
标题翻译：用于检测医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：US20070239046A1
公开(公告)日：2007-10-11
申请号：US11380837
申请日：2006-04-28
申请人： Raja Ghanem , Robert Stadler , Xusheng Zhang
发明人： Raja Ghanem , Robert Stadler , Xusheng Zhang
IPC分类号： A61B5/04
CPC分类号： A61N1/3987 , A61B5/04011 , A61B5/0422 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61B5/7221 , A61B5/7239 , A61N1/05 , A61N1/3621 , A61N1/3925 , A61N1/3956 , Y10S128/901 , Y10S128/902
摘要： A method of detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes forming a first sensing vector and a second sensing vector, and determining whether the sensing of cardiac signals along the first sensing vector and along the second sensing vector is corrupted by noise. If the cardiac signals sensed along both the first sensing vector and the second sensing vector are not corrupted by noise, a determination is made as to whether the cardiac signals sensed along the first sensing vector and along the second sensing vector are one of a first cardiac event and a second cardiac event. The determination of whether the cardiac signals sensed along the first sensing vector and along the second sensing vector are one of a first cardiac event and a second cardiac event is then confirmed.
摘要翻译：一种检测医疗装置中的心脏事件的方法，包括：感测来自形成第一感测向量和第二感测向量的多个电极的心脏信号，以及确定沿着第一感测向量并沿着第二感测的心脏信号的感测矢量被噪音破坏了。如果沿着第一感测向量和第二感测矢量两者感测的心脏信号不被噪声破坏，则确定沿着第一感测向量和沿着第二感测向量感测的心脏信号是否是第一心脏事件和第二次心脏事件。然后确定沿着第一感测向量和沿着第二感测向量感测的心脏信号是否是第一心脏事件和第二心脏事件之一的确定。

60. 发明申请

US20070233196A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A SUBCUTANEOUS MEDICAL DEVICE 有权
标题翻译：用于检测肾上腺髓质瘤的方法和装置
公开(公告)号：US20070233196A1
公开(公告)日：2007-10-04
申请号：US11687108
申请日：2007-03-16
申请人： Robert W. Stadler , Raja N. Ghanem , Xusheng Zhang
发明人： Robert W. Stadler , Raja N. Ghanem , Xusheng Zhang
IPC分类号： A61N1/36
CPC分类号： A61N1/3621 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61N1/3956
摘要： A method and apparatus for detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a first sensing vector and a second sensing vector different from the first sensing vector, determining a characteristic associated with cardiac signals sensed along the first sensing vector during a predetermined sensing window, determining the characteristic associated with cardiac signals sensed along the second sensing vector during the predetermined sensing window; comparing the determined characteristic associated with cardiac signals sensed along the first sensing vector and the determined characteristic associated with cardiac signals sensed along the second sensing vector, and delivering a therapy in response to the comparing.
摘要翻译：一种用于检测医疗装置中的心脏事件的方法和装置，包括感测来自多个电极的心脏信号，所述多个电极形成与第一感测向量不同的第一感测向量和第二感测向量，确定与在预定感测窗口期间沿着第一感测向量感测的心脏信号，在预定感测窗口期间确定与沿着第二感测向量感测的心脏信号相关联的特征; 比较与沿着第一感测矢量感测的心脏信号相关联的确定特征和与沿着第二感测向量感测的心脏信号相关联的确定的特征，以及响应于比较递送治疗。

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