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51. 发明授权

US08498882B2 System for making available individual or pooled, also anonymous patient data on the basis of molecular genome, transcriptome, proteome, epigenome, or metabolome data 有权
标题翻译：基于分子基因组，转录组，蛋白质组学，表观基因组或代谢组学数据，提供个体或汇集的匿名患者数据的系统
公开(公告)号：US08498882B2
公开(公告)日：2013-07-30
申请号：US13147835
申请日：2010-02-08
申请人： Thomas Klein
发明人： Thomas Klein
IPC分类号： G06Q10/00 , G06Q50/00 , C12N5/00 , C12N5/071
CPC分类号： G06F19/3418 , G06F19/00 , G06Q50/22 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for automatically, rapidly, and dynamically funding biological cells for transplantion, treatment, or research purposes between collection centers or banks (storage places) and hospitals, transplant centers, or research facilities, monitoring and assisting with processes from the transmission of requests, the delivery of cell preparation suitable for allogeneic transplantation, and the use of the found preparations to the monitoring of the result in the patient, and making said data available for statistical and other purposes, wherein samples are taken before and after the transplantation to analyze genomes, proteomes, transcriptomes, epigenomes, and/or metbolomes.
摘要翻译：本发明涉及一种用于在收集中心或银行（储存场所）和医院，移植中心或研究设施之间自动，快速和动态地为生物细胞提供移植，治疗或研究目的的系统，监测和协助来自请求的传送，适用于同种异体移植的细胞制备的递送，以及使用所发现的制剂来监测患者的结果，并使所述数据可用于统计学和其他目的，其中样品在前后移植来分析基因组，蛋白质组，转录组，表观基因组和/或metbolomes。

52. 发明申请

US20130070794A1 Dynamical Fabry-Pérot Tuneable Filter Device 有权
标题翻译：动力法布里-Pérot调谐滤波器
公开(公告)号：US20130070794A1
公开(公告)日：2013-03-21
申请号：US13572824
申请日：2012-08-13
申请人： Robert Huber , Wolfgang Wieser , Thomas Klein , Christoph Eigenwillig , Benjamin Biedermann , Dieter Muellner , Michael Eder
发明人： Robert Huber , Wolfgang Wieser , Thomas Klein , Christoph Eigenwillig , Benjamin Biedermann , Dieter Muellner , Michael Eder
IPC分类号： H01S5/06 , G01J3/45
CPC分类号： H01S5/423 , G01J3/26 , G02B6/29358 , G02B26/001 , H01S3/105 , H01S5/02284 , H01S5/141 , H01S5/183
摘要： A Fabry-Pérot tuneable filter device is described with reflecting elements separated by an optical path length to form an optical resonator cavity. A first actuator means is directly or indirectly coupled with a first reflecting element. And the first actuator means is configured to modulate the optical path length between first and second reflecting elements by a modulation amplitude to thereby sweep the optical resonator cavity through a band of optical resonance frequencies with a sweep frequency of 70 kHz or more. And the mechanical coupling between selected elements of the arrangement is sufficiently low such that when operated at the sweep frequency, the selected elements act as a system of coupled oscillating elements. In addition or alternatively, the first actuator means is directly or indirectly coupled with the first reflecting element so as to substantially drive the first reflecting element only.
摘要翻译：通过用光程长度分离的反射元件描述法布里 - 珀罗可调谐滤波器装置，以形成光谐振腔。第一致动器装置与第一反射元件直接或间接耦合。并且第一致动器装置被配置为通过调制幅度来调制第一和第二反射元件之间的光路长度，从而通过具有70kHz或更大的扫频频率的光学谐振频率带扫掠光学谐振腔。并且所述装置的选定元件之间的机械耦合足够低，使得当以扫描频率操作时，所选择的元件用作耦合振荡元件的系统。另外或替代地，第一致动器装置与第一反射元件直接或间接耦合，以便仅基本驱动第一反射元件。

53. 发明申请

US20120308934A1 METHOD FOR PREPARING A COMPOSITE PRINTING FORM 有权
标题翻译：制备复合印刷形式的方法
公开(公告)号：US20120308934A1
公开(公告)日：2012-12-06
申请号：US13570477
申请日：2012-08-09
申请人： Robert W. Hannum , Thomas Klein
发明人： Robert W. Hannum , Thomas Klein
IPC分类号： G03F7/20 , B23K26/38
CPC分类号： G03F7/202
摘要： The invention pertains to a method for preparing a composite printing form from a single precursor that is capable of forming a relief and a carrier. The single precursor can be a single photosensitive element or a single laser-engravable print element having a reinforced elastomeric layer. The single precursor has a size that is at least 70% of a size of the carrier. The single precursor is located on the carrier by approximately positioning the precursor on the carrier that has no registration markings. Precise registration of the single precursor is achieved by using digital information generated from a computer to create the registered image on the composite form. The method is particularly suited for preparing composite printing forms for relief printing, and in particular for preparing composite printing forms for flexographic printing of corrugated substrates.
摘要翻译：本发明涉及从能够形成浮雕和载体的单一前体制备复合印刷形式的方法。单个前体可以是具有增强的弹性体层的单个感光元件或单个可激光雕刻的印刷元件。单一前体的尺寸至少为载体尺寸的70％。通过将前体大约定位在不具有对准标记的载体上，单个前体位于载体上。通过使用从计算机生成的数字信息在复合形式上创建注册的图像来实现单个前体的精确配准。该方法特别适于制备用于凸版印刷的复合印刷形式，特别适用于制备用于波纹状基材的柔性版印刷的复合印刷形式。

54. 发明授权

US08242146B2 Combination of a NSAID and a PDE-4 inhibitor 有权
标题翻译：组合NSAID和PDE-4抑制剂
公开(公告)号：US08242146B2
公开(公告)日：2012-08-14
申请号：US12003129
申请日：2007-12-20
申请人： Thomas Klein , Hans-Peter Kley
发明人： Thomas Klein , Hans-Peter Kley
IPC分类号： A61K31/44
CPC分类号： A61K45/06 , A61K31/00 , A61K2300/00
摘要： The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.
摘要翻译：本发明涉及PDE4抑制剂和常规NSAID在治疗炎性疾病和/或炎症相关疾病中的综合应用，同时最小化胃肠道副作用，例如经常与使用相关的胃糜烂和溃疡的常规NSAIDs。用于该组合的优选的PDE4抑制剂是罗氟司特或其衍生物。用于该组合的优选的常规NSAID是双氯芬酸或其衍生物。

55. 发明申请

US20120048639A1 Steering Device For A Self-Propelled Construction Or Utility Machine And Construction And Utility Machine Having Such A Steering Device 有权
标题翻译：具有这样一个转向装置的自行式施工或实用机器和施工机器的转向装置
公开(公告)号：US20120048639A1
公开(公告)日：2012-03-01
申请号：US13216355
申请日：2011-08-24
申请人： Thomas Haubrich , Thomas Klein
发明人： Thomas Haubrich , Thomas Klein
IPC分类号： B62D5/24 , B62D5/06 , B62D5/18 , B62D3/04
CPC分类号： B62D1/18 , B60N2/062 , E02F9/166 , E02F9/202
摘要： The present invention relates to a steering device for a self-propelled construction or utility machine. The construction or utility machine includes a cab having a carriage, which is adjustable transversely to the travel direction, on which operating and/or actuating elements and at least one steering wheel for steering the construction or utility machine are situated. The steering wheel is coupled via a steering drive shaft, which is mounted on the adjustable carriage, and is carried along upon adjustment, to a steering output shaft, which is situated fixed in place on the construction or utility machine and runs transversely to the steering drive shaft. The steering movements applied to the steering wheel are transmitted by means of a direction change gearing, which is also mounted on the carriage, from the steering drive shaft to the transversely running steering output shaft, the direction change gearing also being carried along upon adjustment of the carriage and being situated so it is axially displaceable to the steering output shaft.
摘要翻译：本发明涉及一种用于自行式建筑或公用事业机器的转向装置。该建筑或公用事业机器包括驾驶室，驾驶室具有横向于行进方向的滑架，操作和/或致动元件以及至少一个用于转向建筑或公用设施的方向盘位于该驾驶室上。方向盘通过转向驱动轴联接，该转向驱动轴安装在可调节的支架上，并且在调节时被携带到转向输出轴上，转向输出轴被固定在施工或公用设备上的适当位置，并横向于转向传动轴。施加到方向盘的转向运动通过方向转换传动装置传递，转向传动装置也安装在滑架上，从转向驱动轴到横向转向的转向输出轴，方向变速装置也随着调整托架并且被定位成使得其可轴向移动到转向输出轴。

56. 发明申请

US20110257999A1 AUTOMATED SYSTEM FOR THE SELECTION AND CONVEYANCE OF STORED ALLOGENEIC BIOLOGICAL CELLS FOR TRANSPLANTATION, THERAPY AND RESEARCH 有权
标题翻译：用于移植，治疗和研究的储存的生物生物细胞的选择和输送的自动化系统
公开(公告)号：US20110257999A1
公开(公告)日：2011-10-20
申请号：US13058759
申请日：2009-08-14
申请人： Thomas Klein , Frank Keller
发明人： Thomas Klein , Frank Keller
IPC分类号： G06Q50/00
CPC分类号： G06F19/322 , G06F19/00 , G06Q50/22 , G06Q50/24 , G16H10/40 , G16H10/60 , G16H50/70
摘要： The invention relates to a system for the automatic, rapid and dynamic conveyance of biological cells for transplant, therapy or research purposes between withdrawalcentres or banks (storage facilities) and clinics, transplant centres or research facilities and also for the monitaring and backing of the processes from request transmission, for supply of a cell specimen which is suitable for the allogeneic transplant, through application of the conveyed specimens to tracking of the results in a patient and the provision of these data for statistical and other purposes. For the first time, the system is able to put forward complete solution proposals for specifically stored transplants online and automatically.
摘要翻译：本发明涉及一种用于在撤离中心或银行（储存设施）和诊所，移植中心或研究设施之间进行移植，治疗或研究目的的生物细胞的自动，快速和动态输送的系统，以及用于监测和支持用于供应适用于同种异体移植的细胞样本的过程，通过将所传送的标本应用于患者的结果的跟踪以及用于统计学和其它目的的这些数据的提供。系统首次能够在线和自动地为特定存储的移植提出完整的解决方案。

57. 发明申请

US20110248541A1 Armrest And Operator Workplace Having Such An Armrest 有权
标题翻译：扶手和操作员工作场所有这样的扶手
公开(公告)号：US20110248541A1
公开(公告)日：2011-10-13
申请号：US13076942
申请日：2011-03-31
申请人： Thomas Haubrich , Thomas Klein
发明人： Thomas Haubrich , Thomas Klein
IPC分类号： B60N2/46 , B60N2/38
CPC分类号： B60N2/773 , B60N2/777 , B60N2/797
摘要： The present invention relates to a machine operator seat of a construction machine having a seat surface, a backrest, which is situated opposite to the front seat edge in the longitudinal direction of the seat surface, and at least one armrest situated laterally to the seat surface, comprising a base part, an arm support, and at least one operating element, the arm support being situated in the rear area in the longitudinal direction and the at least one operating element being situated in the front area of the armrest in the longitudinal direction. Furthermore, the present invention relates to a construction machine, in particular a road miller, recycler, stabilizer, or a road roller, in particular a tandem roller, having such a machine operator seat.
摘要翻译：本发明涉及一种施工机械的机器操作者座椅，其具有座位表面，靠背，其位于座椅表面的纵向方向上与前座椅边缘相对的位置，以及至少一个位于座位表面侧面的扶手，其包括基部，臂支撑件和至少一个操作元件，所述臂支撑件沿纵向方向位于后区域中，并且所述至少一个操作元件位于所述扶手的前部区域中的纵向方向。此外，本发明涉及一种具有这种机器操作员座椅的建筑机械，特别是道路铣刀，回收机，稳定器或具有串联辊的压路机。

58. 发明申请

US20110092510A1 DPP-IV INHIBITORS FOR USE IN THE TREATMENT OF NAFLD 审中-公开
标题翻译： DPP-IV抑制剂用于治疗NAFLD
公开(公告)号：US20110092510A1
公开(公告)日：2011-04-21
申请号：US12995474
申请日：2009-06-02
申请人： Thomas Klein , Michael Mark , Heiko Niessen , Leo Thomas
发明人： Thomas Klein , Michael Mark , Heiko Niessen , Leo Thomas
IPC分类号： A61K31/4985 , A61K31/40 , A61K31/403 , A61K31/506 , A61K31/52 , A61K31/5025 , A61K31/519 , A61K31/4439 , A61P3/00 , A61P9/10 , A61P29/00 , A61P9/12
CPC分类号： A61K31/40 , A61K31/155 , A61K31/403 , A61K31/41 , A61K31/4184 , A61K31/4196 , A61K31/422 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/522 , A61K31/53 , A61K45/06 , A61P1/16 , A61K2300/00
摘要： The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing non alcoholic fatty liver diseases (NAFLD).
摘要翻译：本发明涉及某些DPP-4抑制剂特别适用于治疗和/或预防非酒精性脂肪肝疾病（NAFLD）的发现。

59. 发明申请

US20100144576A1 DISH DETERGENT 审中-公开
标题翻译：洗碗剂
公开(公告)号：US20100144576A1
公开(公告)日：2010-06-10
申请号：US12523673
申请日：2008-01-18
申请人： Thomas Klein , Ralf-Johann Moritz , Thomas Staffel , Jürgen Straub
发明人： Thomas Klein , Ralf-Johann Moritz , Thomas Staffel , Jürgen Straub
IPC分类号： C11D3/395
CPC分类号： C11D3/33 , C11D3/0073 , C11D3/06
摘要： The present invention relates to the use of a reduced-phosphate builder system based on alkali metal tripolyphosphate and sodium iminodisuccinate for producing material-protective dishwashing detergent formulations for automatic machine dishwashing.
摘要翻译：本发明涉及使用基于碱金属三聚磷酸盐和亚氨基二琥珀酸钠的还原磷酸盐助洗剂体系，用于生产用于自动洗碗机洗涤的食品保护性餐具洗涤剂配方。

60. 发明申请

US20090224453A1 Attachment device for a clamp and combination of a clamp and at least one attachment device 有权
标题翻译：用于夹具的夹紧装置和夹具与至少一个附接装置的组合
公开(公告)号：US20090224453A1
公开(公告)日：2009-09-10
申请号：US12075128
申请日：2008-03-07
申请人： Michael Duss , Thomas Klein , Hans Roesch
发明人： Michael Duss , Thomas Klein , Hans Roesch
IPC分类号： B23Q3/02
CPC分类号： B25B5/163
摘要： Attachment device for a clamp, said clamp having at least one clamp contact member for workpieces, said attachment device comprising a fixing member for fixing the attachment device in a releasable manner to the at least one clamp contact member, an attachment device contact member for contacting workpieces, which is held on the fixing member, and a pivot bearing via which the attachment device contact member is pivotable with regard to the fixing member.
摘要翻译：用于夹具的附接装置，所述夹具具有用于工件的至少一个夹紧接触构件，所述附接装置包括用于将所述附接装置以可释放的方式固定到所述至少一个夹紧接触构件的固定构件，用于接触的附接装置接触构件保持在固定构件上的工件和枢轴承座，连接装置接触构件可通过枢轴轴承相对于固定构件枢转。

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