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51. 发明授权

US07238707B2 Substituted pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译：取代的戊醇，其生产方法及其作为抗炎剂的用途
公开(公告)号：US07238707B2
公开(公告)日：2007-07-03
申请号：US10957742
申请日：2004-10-05
申请人： Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke
发明人： Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke
IPC分类号： A61K31/47 , A61K31/44 , C07D217/22 , C07D215/38
CPC分类号： C07D215/38 , C07D217/22
摘要： The invention relates to substituted pentanols, a process for their production and their use as anti-inflammatory agents.
摘要翻译：本发明涉及取代戊醇，其制备方法及其作为抗炎剂的用途。

52. 发明申请

US20070129359A1 Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents 审中-公开
标题翻译：四氢萘衍生物，其制备方法及其作为抗炎剂的用途
公开(公告)号：US20070129359A1
公开(公告)日：2007-06-07
申请号：US11414556
申请日：2006-05-01
申请人： Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
发明人： Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
IPC分类号： A61K31/538 , A61K31/498 , A61K31/4745 , A61K31/4704 , A61K31/404 , A61K31/4035
CPC分类号： C07C233/74 , C07C217/74 , C07C275/28 , C07C311/20 , C07C2602/10
摘要： The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (I) processes for their preparation and their use as anti-inflammatory agents.
摘要翻译：本发明涉及式（I）的多取代四氢萘衍生物，其制备方法及其作为抗炎剂的用途。

53. 发明申请

US20060281744A1 Inhibitors of soluble adenylate cyclase 失效
标题翻译：可溶性腺苷酸环化酶抑制剂
公开(公告)号：US20060281744A1
公开(公告)日：2006-12-14
申请号：US11448140
申请日：2006-06-07
申请人： Bernd Buchmann , Martin Fritsch , Duy Nguyen , Bernd Menzenbach , Ulf Boemer
发明人： Bernd Buchmann , Martin Fritsch , Duy Nguyen , Bernd Menzenbach , Ulf Boemer
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/381 , A61K31/4436 , C07D409/02 , C07D413/02
CPC分类号： C07D307/85 , C07D333/60
摘要： The invention relates to compounds of general Formula I, the production thereof, and the use thereof as a medicinal product.
摘要翻译：本发明涉及通式Ⅰ的化合物，其制备方法及其作为药用产品的用途。

54. 发明申请

US20060079892A1 Adjustable tandem connectors for corrective devices for the spinal column and other bones and joints 审中-公开
标题翻译：用于脊柱和其他骨骼和关节的校正装置的可调式串联连接器
公开(公告)号：US20060079892A1
公开(公告)日：2006-04-13
申请号：US10238877
申请日：2002-09-10
申请人： Suranjan Roychowdhury , Duy Nguyen , Jeffrey Cota
发明人： Suranjan Roychowdhury , Duy Nguyen , Jeffrey Cota
IPC分类号： A61F2/30
CPC分类号： A61B17/7044 , A61B17/645 , A61B17/705
摘要： Connectors for interconnecting rods, fixed to vertebrae and other bones of a subject include a body portion and two recesses or pockets for receiving the rods. These connectors are generally able to be secured to the rods by a tightening a fastener or retaining member from above the spine, which can facilitate the procedure for the surgeon. The connectors can include rotatable or stationary pockets, mating members that pivot and/or translate within the coronal plane of the subject to adjust to the positions of the rods, and extension shafts that pivot to adjust for rod angle.
摘要翻译：固定到主体的椎骨和骨骼的互连杆的连接器包括主体部分和用于接收杆的两个凹部或凹部。这些连接器通常能够通过从脊柱上方紧固紧固件或保持构件而固定到杆上，这可以便于外科医生的手术。连接器可以包括可旋转的或固定的凹穴，在对象的冠状平面内枢转和/或平移的配合构件，以调节到杆的位置，以及枢转以调节杆角度的延伸轴。

55. 发明申请

US20060074084A1 Inhibitors of soluble adenylate cyclase 审中-公开
标题翻译：可溶性腺苷酸环化酶抑制剂
公开(公告)号：US20060074084A1
公开(公告)日：2006-04-06
申请号：US11233533
申请日：2005-09-23
申请人： Duy Nguyen , Anne Mengel , Martin Fritsch , Gernor Langer , Ulf Boemer , Knut Eis , Bernd Menzenbach , Bernd Buchmann , Seock-Kyu Khim
发明人： Duy Nguyen , Anne Mengel , Martin Fritsch , Gernor Langer , Ulf Boemer , Knut Eis , Bernd Menzenbach , Bernd Buchmann , Seock-Kyu Khim
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4439 , A61K31/405 , C07D413/02 , C07D405/02 , C07D403/02
CPC分类号： C07D405/12 , C07D209/42 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D417/12
摘要： The invention relates to compounds of general formula I as well as their production and use as a medication.
摘要翻译：本发明涉及通式I的化合物及其作为药物的生产和用途。

56. 发明申请

US20050267202A1 Chromanol derivatives, a process for their production and their use as anti-inflammatory agents 审中-公开
标题翻译：色甘醇衍生物，其生产方法及其作为抗炎剂的用途
公开(公告)号：US20050267202A1
公开(公告)日：2005-12-01
申请号：US11130393
申请日：2005-05-17
申请人： Duy Nguyen , Heike Schaecke , Konrad Krolikiewicz
发明人： Duy Nguyen , Heike Schaecke , Konrad Krolikiewicz
IPC分类号： A61K31/353
CPC分类号： C07D405/12
摘要： The invention relates to compounds of formula I, a process for their production, and their use as anti-inflammatory agents.
摘要翻译：本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。

57. 发明申请

US20050222154A1 Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 审中-公开
标题翻译：多取代四氢萘衍生物，其制备方法及其作为抗炎剂的用途
公开(公告)号：US20050222154A1
公开(公告)日：2005-10-06
申请号：US10961375
申请日：2004-10-12
申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号： A61K31/498 , A61K31/502 , A61K31/517 , A61K31/538
CPC分类号： C07D217/24 , C07D215/227 , C07D237/32 , C07D239/74
摘要： The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as anti-inflammatory agents.
摘要翻译：本发明涉及式（I）的多取代四氢萘衍生物的制备方法及其作为抗炎剂的用途。

58. 发明授权

US06333005B1 Methods of preventing scaling involving inorganic compositions in combination with copolymers of maleic anhydride and isobutylene, and compositions therefor 失效
标题翻译：防止涉及无机组合物与马来酸酐和异丁烯的共聚物结合的结垢方法及其组合物
公开(公告)号：US06333005B1
公开(公告)日：2001-12-25
申请号：US09589886
申请日：2000-06-09
申请人： Duy Nguyen
发明人： Duy Nguyen
IPC分类号： C23F1106
CPC分类号： C02F5/105 , C02F5/00 , C02F2209/06
摘要： Method for inhibiting scale deposits in an aqueous system. The method includes at least one of adding and forming anti-scalant in the aqueous system, wherein the anti-scalant comprises at least one of polyvalent metal silicate and polyvalent metal carbonate, and adding copolymer of maleic anhydride and isobutylene. A composition includes at least one of polyvalent metal silicate and polyvalent metal carbonate, copolymer of maleic anhydride and isobutylene, and wherein a weight ratio of the at least one polyvalent metal silicate and polyvalent metal carbonate to the copolymer is from about 50:1 to 1:1.
摘要翻译：用于抑制水性体系中结垢的方法。该方法包括在水性体系中添加和形成抗鳞屑剂中的至少一种，其中抗腐剂包含多价金属硅酸盐和多价金属碳酸盐中的至少一种，并加入马来酸酐和异丁烯的共聚物。组合物包括多价金属硅酸盐和多价金属碳酸盐中的至少一种，马来酸酐和异丁烯的共聚物，并且其中至少一种多价金属硅酸盐和多价金属碳酸盐与共聚物的重量比为约50:1至1 ：1。

59. 发明授权

US5024151A Refuse compactor 失效
标题翻译：垃圾压实机
公开(公告)号：US5024151A
公开(公告)日：1991-06-18
申请号：US359439
申请日：1989-05-31
申请人： Guy Girardin , Pierre Morin , Duy Nguyen , Duc Nguyen , Louise Brunelle
发明人： Guy Girardin , Pierre Morin , Duy Nguyen , Duc Nguyen , Louise Brunelle
IPC分类号： B30B9/30
CPC分类号： B30B9/3032 , B30B9/30 , B30B9/3003
摘要： Disclosed is a refuse compactor particularly designed for aircrafts, which comprises a compaction chamber having a movable wall panel that extends parallel to one of the side wall of the compaction chamber, and can be moved away from this side wall through a very simple mechanism which is operated either directly by a hand-lever or indirectly through the service door of the compactor cabinet when this service door is closed for refuse compaction into a container. In both cases, the very purpose of this lateral motion of the movable wall panel relative to the adjacent side wall is to release the pressure of the refuse container inside the compaction chamber after completion of the compaction, and thus makes this container easily discardable into a storage chamber if any, or out of the compactor. The operation of the movable wall panel is exclusively mechanical and is therefore very simple and reliable.
摘要翻译：公开了一种特别设计用于飞机的垃圾压实机，其包括压实室，该压实室具有平行于压实室的侧壁之一延伸的可移动壁板，并且可以通过非常简单的机构远离该侧壁移动，当这个维修门被关闭以便垃圾压实到容器中时，它们可以直接由手柄操纵或间接地通过压实机柜的维修门操作。在这两种情况下，可移动壁板相对于相邻侧壁的横向运动的目的是在压实完成之后释放压实室内的垃圾容器的压力，从而使该容器容易地丢弃成如果有的话，或者从压实机出来。可动壁板的操作是机械的，因此非常简单可靠。

60. 发明授权

US11458200B2 Constructs, agents, and methods for facilitated ablation of cardiac tissue 有权
公开(公告)号：US11458200B2
公开(公告)日：2022-10-04
申请号：US16099108
申请日：2017-05-04
申请人： William Sauer , Duy Nguyen
发明人： William Sauer , Duy Nguyen
IPC分类号： A61K41/00 , A61B18/02 , A61B18/14 , A61B18/00 , A61K9/127 , A61K9/51 , A61K31/366 , A61K33/244 , A61K33/26 , A61K45/06 , A61K49/18 , A61N2/00 , A61P41/00
摘要： The presently disclosed subject matter provides agents, compositions, and methods for augmenting ablation of a target tissue in a subject in need thereof, for example, using agents that modulate protective and/or reparative cellular processes induced in target tissue by application of ablative energy to the target tissue to sensitize the target tissue to the ablative energy. The presently disclosed subject matter further provides methods for augmenting radiofrequency ablation of cardiac tissue, for example, by applying radiofrequency energy to ablate cardiac tissue in the presence of metallic nanoparticles magnetically guided to the cardiac tissue.

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