专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US06833249B2 Quick and sensitive method of quantifying mycolic acid to develop anti-microbial agents and a diagnostic kit thereof 失效
标题翻译：快速和敏感的定量霉菌酸开发抗微生物剂的方法及其诊断试剂盒
公开(公告)号：US06833249B2
公开(公告)日：2004-12-21
申请号：US10102939
申请日：2002-03-22
申请人： Suman Preet Singh Khanuja , Suchi Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Ajit Kumar Shasany
发明人： Suman Preet Singh Khanuja , Suchi Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Ajit Kumar Shasany
IPC分类号： C12Q118
CPC分类号： C12Q1/18 , Y10S435/975
摘要： The present invention relates to a rapid, sensitive, simple, and cost-effective spectrophotometric method of detecting and quantifying mycolic acid in a mycolic acid-fuschin dye complex with absorbance maxima ranging between 490-500 nm in the presence of various test compounds, for screening mycolic acid biosynthesis inhibitors useful as anti-microbial agents and a diagnostic kit thereof comprising basic fuschin dye in the concentration ranging between 0.1-1.0 gm/100 ml, phenol and 95% ethanol in the ratio ranging between 1:4 to 2:1 (v/v), and phenol and distilled water in the ratio ranging between 1:14 to 1:25.
摘要翻译：本发明涉及快速，灵敏，简单且成本有效的分光光度法，用于在各种试验化合物的存在下，在490-500nm范围内检测和定量霉菌酸 - 富梳素染料络合物中的霉菌酸，用于筛选可用作抗微生物剂的霉菌酸生物合成抑制剂及其诊断试剂盒，其包含浓度范围为0.1-1.0gm / 100ml的基本fuschin染料，苯酚和95％乙醇之间的比例为1:4至2:1 （v / v），苯酚和蒸馏水的比例范围为1:14至1:25。

52. 发明授权

US06677463B1 Single pot conversion of artemisinin to artesunic acid 失效
标题翻译：青蒿素对青蒿琥酯的单锅转化
公开(公告)号：US06677463B1
公开(公告)日：2004-01-13
申请号：US10315921
申请日：2002-12-10
申请人： Rajendra Singh Bhakuni , Atul Prakash Kahol , Tarun Singh , Suman Preet Singh Khanuja
发明人： Rajendra Singh Bhakuni , Atul Prakash Kahol , Tarun Singh , Suman Preet Singh Khanuja
IPC分类号： C07D32300
CPC分类号： C07D493/08 , C07D493/18
摘要： The present invention provides a single pot process for the preparation of artesunic acid from artemisinin involving reduction followed by esterification of the reduced product at room temperature.
摘要翻译：本发明提供了一种用于从青蒿素制备青蒿琥酯的单锅法，其涉及还原，然后在室温下酯化还原产物。

53. 发明授权

US07579491B2 Process for preparing brevifoliol 有权
标题翻译：短纤维酚的制备方法
公开(公告)号：US07579491B2
公开(公告)日：2009-08-25
申请号：US11548166
申请日：2006-10-10
申请人： Sunil Kumar Chattopadhyay , Sachin Srivastava , Arvind Singh Negi , Ranganathan Santha Kumar Tirupadiripuliyur , Ankur Garg , Suman Preet Singh Khanuja
发明人： Sunil Kumar Chattopadhyay , Sachin Srivastava , Arvind Singh Negi , Ranganathan Santha Kumar Tirupadiripuliyur , Ankur Garg , Suman Preet Singh Khanuja
IPC分类号： C07D305/00 , A61K36/13
CPC分类号： C07C67/56 , C07C2603/30 , C07C69/78
摘要： The present invention provides a process for production of an anticancer taxoid brevifoliol of the formula I from plants belonging to the genus Taxus by first extracting the dried and pulverized leaves of the plant with an alcohol preferably at a temperature in the range of 20-40° C. and then. concentrating the solvent to obtain an alcoholic extract. The alcoholic extract obtained is then adsorbed with an adsorbent and the resulting adsorbed material is then dried at a temperature ranging from 20-50° C. for 4-48 hours. The dried adsorbed material is then extracted with a combination of an aliphatic solvent and a chlorinated solvent successively and concentrated to obtain a residue. The residue is subjected to gross fractionation using column chromatography such as silica gel, florosil and silicic acid followed by chromatography with a suitable adsorbent to get brevifoliol.
摘要翻译：本发明提供了一种通过首先用醇优选在20-40℃的温度下提取植物的干燥和粉碎的叶来生产属于紫杉属的植物的式I的抗癌紫杉烷类短纤维醇的方法 C.然后。浓缩溶剂以获得醇提取物。然后将所得醇提物用吸附剂吸附，然后将所得吸附材料在20-50℃的温度范围内干燥4-48小时。然后将干燥的吸附材料用脂肪族溶剂和氯化溶剂的组合连续萃取并浓缩，得到残余物。使用柱色谱法如硅胶，佛罗里达和硅酸对残余物进行粗分馏，然后用合适的吸附剂进行色谱以得到短纤维醇。

54. 发明授权

US06833143B1 Process for the preparation of a extract rich in bacosides from the herb Bacopa monniera 失效
标题翻译：从草药Bacopa monniera制备富含芽孢杆菌的提取物的方法
公开(公告)号：US06833143B1
公开(公告)日：2004-12-21
申请号：US10400192
申请日：2003-03-26
申请人： Atul Prakash Kahol , Tarun Singh , Sudeep Tandon , Madan Mohan Gupta , Suman Preet Singh Khanuja
发明人： Atul Prakash Kahol , Tarun Singh , Sudeep Tandon , Madan Mohan Gupta , Suman Preet Singh Khanuja
IPC分类号： A61K3578
CPC分类号： A61K36/80
摘要： The present invention provides a novel process for the preparation of bacosides enriched fraction in a non-hygroscopic form the extract of Bacopa monniera, the said process comprising the steps of drying freshly harvested herb in a hot air oven at 37-42° C., powdering and sieving the dried herb to obtain powder of 30-40 mesh size, defatting the powdered herb with hexane in a modified soxhlet extractor, extracting the defatted powdered herb with acetone, again extracting the same herb with methanol to obtain an extract containing bacosides, concentrating the extract to one twentieth of its original volume under reduced pressure, gradually adding the concentrated extract to acetone for precipitating the bacosides, filtering the bacosides in a Nutsche type vacuum filter, dissolving the crude bacoside mass into 2-10 parts water, extracting the bacoside solution with n-butanol to selectively transfer the bacosides to the solvent phase, separating and concentrating the solvent phase under vacuum to obtain semi-dry mass, dissolving the semi dried mass into 2-10 parts water, adding and stirring 1-5% of &bgr;-cyclodextrin to stabilize the bacosides, spray drying the stabilized bacoside solution by maintaining hot air temperature at 90-110° C., to obtain a stable free flowing fraction of Bacopa monniera rich in bacosides.
摘要翻译：本发明提供了一种用于制备以非吸湿形式的Bacopa monniera提取物富集杆菌的部分的新方法，所述方法包括以下步骤：在37-42℃的热空气烘箱中干燥新鲜收获的草本植物，粉碎和筛分干草，得到30-40目尺寸的粉末，用改性索氏提取器用己烷脱脂粉末，用丙酮提取脱脂粉末草药，再次用甲醇提取相同的草本，得到含有药剂的提取物，将提取物在减压下浓缩至其原始体积的二十分之一，逐渐将浓缩提取物加入到丙酮中沉淀芽孢杆菌，过滤Nutsche型真空过滤器中的芽孢杆菌，将粗制药物块溶解在2-10份水中，使用正丁醇选择性转移杆菌苷至溶剂相，分离和浓缩溶剂相获得半干质量，将半干质量溶解在2-10份水中，加入并搅拌1-5％的β-环糊精以稳定芽孢杆菌，通过将热空气温度保持在90℃喷雾干燥稳定的bacoside溶液， 110℃，以获得富含芽孢杆菌的Bacopa monniera的稳定的自由流动分数。

55. 发明授权

US07767798B2 Loganin analogues and a process for the preparation thereof 有权
标题翻译： Loganin类似物及其制备方法
公开(公告)号：US07767798B2
公开(公告)日：2010-08-03
申请号：US11366687
申请日：2006-03-02
申请人： Suman Preet Singh Khanuja , Santosh Kumar Srivastava , Ankur Garg , Merajuddin Khan , Mahendra Pandurang Dardokar , Anirban Pal
发明人： Suman Preet Singh Khanuja , Santosh Kumar Srivastava , Ankur Garg , Merajuddin Khan , Mahendra Pandurang Dardokar , Anirban Pal
IPC分类号： C07H15/00
CPC分类号： C07H17/04
摘要： The present invention provides novel loganin analogues and a process for the preparation thereof. The present invention further provides the use of Iridoid glycoside loganin isolated from the fruit pulp of Strychnos nux-vomica and its bioactive semi-synthetic analogues against various human cancer cell lines grown in-vitro.
摘要翻译：本发明提供新的类胡萝卜素类似物及其制备方法。本发明还提供了从Strychnos nux-vomica的果实果肉中分离出的Iridoid苷苷和其生物活性半合成类似物对体外生长的各种人类癌细胞系的用途。

56. 发明授权

US07196115B2 Pharmaceutical composition containing brevifoliol for use in chemotherapeutic treatment of human beings, method therefor 失效
标题翻译：含有短寿菌酚的药物组合物，用于化疗人类的治疗方法
公开(公告)号：US07196115B2
公开(公告)日：2007-03-27
申请号：US10334675
申请日：2002-12-30
申请人： Suman Preet Singh Khanuja , Ranganathan Santha Kumar Tirupadiripuliyur , Ankur Garg , Raghvendra Kumar Mishra , Sunil Kumar Chattopadhyay , Sachin Srivastava , Arvind Singh Negi
发明人： Suman Preet Singh Khanuja , Ranganathan Santha Kumar Tirupadiripuliyur , Ankur Garg , Raghvendra Kumar Mishra , Sunil Kumar Chattopadhyay , Sachin Srivastava , Arvind Singh Negi
IPC分类号： A61K3/21 , A61K31/335
CPC分类号： A61K31/235
摘要： The present invention relates to the bioactivity of taxanes isolated from the leaves of Himalayan Yew tree Taxus wallichiana against human cancer cell lines grown in-vitro and subsequent identification of brevifoliol [1] as anticancer agent useful in the treatment of various types of cancer in humans
摘要翻译：本发明涉及从喜马拉雅红豆杉红豆杉叶片分离出的紫杉醇对体外生长的人类癌细胞系的生物活性，随后鉴定了作为可用于治疗人类各种癌症的抗癌剂的短纤维酚[1]

57. 植物专利

USPP12791P2 Novel, high yielding stable Mentha arvensis plant named ‘Damroo’ 有权
标题翻译：新型高产稳定的薄荷植物名为“Damroo”
公开(公告)号：USPP12791P2
公开(公告)日：2002-07-23
申请号：US09537508
申请日：2000-03-29
申请人： Nirmal Kumar Patra , Sushil Kumar , Suman Preet Singh Khanuja , Ajit Kumar Shasney , Alok Kalra , Herikesh Bahadur Singh , Hemendra Pratap Singh , Ved Ram Singh , Hasan Tanveer , Nareshwar Mengi , Dharmendra Kumar Rajput , Mahendra Singh Negi , Neeraj Kumar Tyagi , Paltoo Ram , Vijay Pal Singh , Ram Sajeevan Shukla , Birendra Kumar , Jitendra Pratap Singh , Raja Ram , Vijay Kumar , Shiv Ram Sharma
发明人： Nirmal Kumar Patra , Sushil Kumar , Suman Preet Singh Khanuja , Ajit Kumar Shasney , Alok Kalra , Herikesh Bahadur Singh , Hemendra Pratap Singh , Ved Ram Singh , Hasan Tanveer , Nareshwar Mengi , Dharmendra Kumar Rajput , Mahendra Singh Negi , Neeraj Kumar Tyagi , Paltoo Ram , Vijay Pal Singh , Ram Sajeevan Shukla , Birendra Kumar , Jitendra Pratap Singh , Raja Ram , Vijay Kumar , Shiv Ram Sharma
IPC分类号： A01H500
CPC分类号： A01H5/12
摘要： A novel Mentha arvensis mint population-variety ‘Damroo’ capable of producing viable seeds and phenotypically homogeneous seed-derived plant population when cross pollinated within its own population and capable of high yield of mint oil.
摘要翻译：一种新颖的薄荷种植品种“Damroo”，能够在自己的种群内交叉授粉并能够获得高产量的薄荷油，能够生产活的种子和表型均匀的种子来源植物种群。

58. 植物专利

USPP20149P2 New and distinct somaclonal variety of rose scented geranium 有权
标题翻译：玫瑰香草天竺葵新颖独特的体细胞克隆品种
公开(公告)号：USPP20149P2
公开(公告)日：2009-07-07
申请号：US09539992
申请日：2000-03-30
申请人： Gauri Saxena , Suchitra Banerjee , Laiq ur Rahman , Gopal Rao Mallavarapu , Srikant Sharma , Suman Preet Singh Khanuja , Sushil Kumar
发明人： Gauri Saxena , Suchitra Banerjee , Laiq ur Rahman , Gopal Rao Mallavarapu , Srikant Sharma , Suman Preet Singh Khanuja , Sushil Kumar
IPC分类号： A01H5/00
CPC分类号： A01H6/42 , A01H5/02 , Y02A40/14
摘要： A new and distinct somaclone of rose scented geranium Pelargonium graveolens christened ‘Parimal’ characterized by distinct morphology and improved oil yield determining parameters.
摘要翻译：玫瑰香薰天竺葵的新鲜而独特的香草天竺葵，被称为“Parimal”，具有不同的形态和改善的油产量决定参数。

59. 发明授权

US07435433B2 Process for the isolation of oleane compounds isolated from the bark of arjun tree terminalia arjuna (Roxb.) 失效
标题翻译：用于分离从jun木树皮树皮分离的油类化合物的方法（Roxb。）
公开(公告)号：US07435433B2
公开(公告)日：2008-10-14
申请号：US11395734
申请日：2006-03-31
申请人： Suman Preet Singh Khanuja , Madan Mohan Gupta , Santosh Kumar Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Digvijay Singh , Subash Chandra Verma , Ankur Grag , Merajuddin Khan , Ram Kishor Verma , Raghavendra Kumar Mishra , Subash Chandra Singh
发明人： Suman Preet Singh Khanuja , Madan Mohan Gupta , Santosh Kumar Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Digvijay Singh , Subash Chandra Verma , Ankur Grag , Merajuddin Khan , Ram Kishor Verma , Raghavendra Kumar Mishra , Subash Chandra Singh
IPC分类号： A61K36/00
CPC分类号： C07J63/008
摘要： The present invention provides an improved process for the isolation of oleane compounds from the bark of Terminalia arjuna (Roxb.). More particularly, the present invention relates to an improved process for the isolation of arjunic acid and its derivates from the bark of Terminalia arjuna (Roxb.). The present invention further provides the identification of arjunic acid [1] and its derivatives as anticancer agent useful in the treatment of various types of cancer in humans.
摘要翻译：本发明提供了一种从Terminalia arjuna（Roxb。）的树皮中分离含油化合物的改进方法。更具体地说，本发明涉及一种改进的方法，用于分离来自Terminalia arjuna（Roxb。）的树皮的丙烯酸及其衍生物。本发明进一步提供了用于治疗人类各种类型癌症的抗癌剂的弓状酸[1]及其衍生物的鉴定。

60. 发明授权

US06893668B2 Process for isolation of anticancer agent camptothecin from Nothapodytes foetida 失效
标题翻译：从Nothapodytes foetida中分离抗癌剂喜树碱的方法
公开(公告)号：US06893668B2
公开(公告)日：2005-05-17
申请号：US10402149
申请日：2003-03-31
申请人： Santosh Kumar Srivastava , Merajuddin Khan , Suman Preet Singh Khanuja
发明人： Santosh Kumar Srivastava , Merajuddin Khan , Suman Preet Singh Khanuja
IPC分类号： C07D491/22 , A61K35/78 , A61K31/44
CPC分类号： C07D491/22
摘要： The present invention relates to an improved and economical process for the isolation of anticancer agent Camptothecin from the twigs and stem of Nothapodytes foetida using hot extraction 20(S) Camptothecin is an alkaloid, which contains a pentacyclic ring system that includes a pyrrolo [3,4-b] quinoline moiety (ring A, B and C), the pyridone ring D and a chiral center at C-20 in ring E.
摘要翻译：本发明涉及一种改进和经济的方法，用于使用热提取从异烟肼（Nothapodytes foetida）的枝杈和茎中分离抗癌剂喜树碱20（S）喜树碱是一种生物碱，其包含五环系统，其包含吡咯并[3， 4-b]喹啉部分（环A，B和C），吡啶环D和C环C的手性中心。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式