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    • 54. 发明授权
    • Catheter with steerable stylet
    • 导管带导管
    • US5674271A
    • 1997-10-07
    • US749293
    • 1996-11-14
    • Stephen Denker
    • Stephen Denker
    • A61M25/01A61N1/05
    • A61N1/056A61M25/0152
    • An electrode lead for intracorporeal stimulation of body tissue includes a tubular electrode cable and a removable stylet therein for guiding the cable during insertion through a blood vessel and heart chambers. The electrode cable has a flexible conductor extending through an insulating sheath which has a tubular shape forming a lumen. An exposed electrode, to which the conductor connects, closes a distal end of the electrode cable, while the proximate end of the electrode cable is grasped by an operator. The stylet extends from the distal cable end to the proximate end and engages the operator. The stylet has an outer tube forming a stylet lumen with a longitudinal axis and an inner wire which extends through the stylet lumen. The inner wire and outer tube are attached on one side of the longitudinal axis adjacent their distal ends, so that movement of the inner wire with respect to the outer tube causes curvature of the outer tube which in turn bends the electrode cable for steering through the blood vessel. After the electrode cable has been positioned at the desired location for stimulation, the stylet is removed.
    • 用于身体组织的体内刺激的电极引线包括管状电极电缆和其中的可移除的探针,用于在穿过血管和心室插入期间引导电缆。 电极电缆具有延伸穿过绝缘护套的柔性导体,其具有形成内腔的管状形状。 导体连接的暴露的电极封闭电极电缆的远端,而电极电缆的近端由操作者掌握。 探针从远端电缆端延伸到近端,并与操作者接合。 探针具有形成具有纵轴的探针腔的外管和延伸穿过探针管腔的内线。 内线和外管在纵向轴线的一侧邻近其远端附接,使得内线相对于外管的运动导致外管的弯曲,而外管的弯曲又弯曲电极缆线,用于转向通过 血管 在将电极电缆定位在所需的位置进行刺激之后,探针将被去除。
    • 55. 发明授权
    • Cardiac pacer which compensates for effects of abrupt changes in heart
rate
    • 心脏起搏器补偿心率突然变化的影响
    • US5545185A
    • 1996-08-13
    • US363139
    • 1994-12-23
    • Stephen Denker
    • Stephen Denker
    • A61N1/362A61N1/39A61N1/365
    • A61N1/3962A61N1/3621
    • Clinical studies of heart patients have demonstrated that ventricular tachyarrhythmia often is preceded by a foreshortened cardiac cycle length followed by a relatively long compensatory pause, thus producing in an abrupt short-to-long cycle length change. An implantable apparatus for preventing tachyarrhythmia measures the cardiac cycle length and detects the occurrence of a foreshortened cardiac cycle length more than a predefined amount between consecutive cycles. When a normal heart beat does not occur within a predefined period of time after such an abrupt change in cycle length, the resulting compensatory pause is eliminated by a cardiac pacer applying an appropriately timed electrical pulse to produce a contraction of the heart. The apparatus also includes a defibrillator to shock the heart in the event that the preventive pacing is not effective.
    • 心脏病患者的临床研究已经证明,室性快速性心律失常通常在缩短的心脏周期长度之前进行,之后是相对较长的补偿性暂停,从而产生突然的短期至长周期长度变化。 用于预防快速性心律失常的可植入装置测量心脏周期长度,并且在连续循环之间检测出缩短的心循环长度大于预定量的发生。 当在周期长度的这种突然变化之后的预定时间段内不发生正常心跳时,通过应用适当定时的电脉冲以产生心脏的收缩的心脏起搏器消除所得到的补偿性暂停。 该装置还包括在预防性起搏不起作用的情况下使心脏震颤的除颤器。