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51. 发明授权

US5380275A Device for irrigating a natural body orifice of a person seated on a toilet 失效
标题翻译：用于冲洗坐在马桶上的人的天然人体孔的装置
公开(公告)号：US5380275A
公开(公告)日：1995-01-10
申请号：US52319
申请日：1993-04-23
申请人： Kenneth Kensey , Joseph Kaufmann
发明人： Kenneth Kensey , Joseph Kaufmann
IPC分类号： A61M3/02 , A61M1/00
CPC分类号： A61M3/0225 , A61M3/0241
摘要： A device for administering a liquid into the body of a person through a natural orifice, e.g., the anus or vagina, while the person is seated on a toilet. The device comprises a base unit, an extendable tube having a distal end, and a vessel containing the liquid for introduction into person. The base unit comprises a saddle arranged for disposition under the toilet seat and configured to be disposed between the buttocks of the person when he/she is seated the seat. A positionable guide tube extends through a portion of the saddle from an entrance point adjacent the front of the toilet to an opening located at a position adjacent the natural orifice, e.g., anus or vagina, when the person is seated. The extendable tube has a distal end portion arranged to be inserted by the person into the guide tube and through the opening, and the guide tube is arranged to be slid with respect to the saddle, so that the distal end portion of the extendable tube is directed upward and enters the natural orifice. The vessel is coupled to the extendable tube by a pump and associated connector so that the liquid within the vessel can be pumped through the extendable tube into the person's body.
摘要翻译：一种用于在人坐在马桶上时通过自然孔口（例如肛门或阴道）将液体施用到人体内的装置。该装置包括基座单元，具有远端的可延伸管和容纳用于引入人的液体的容器。基座单元包括安置在马桶座下方的马鞍，并且构造成当他/她坐在座椅上时设置在人的臀部之间。当座位时，可定位的引导管从邻近马桶的前部的入口处延伸穿过鞍座的一部分，位于邻近自然孔的位置处的开口，例如肛门或阴道。可伸缩管具有被设置成被人插入引导管并穿过开口的远端部分，并且引导管被布置成相对于鞍座滑动，使得可延伸管的远端部分为向上并进入自然孔。容器通过泵和相关联的连接器联接到可延伸管，使得容器内的液体可以通过可延伸管泵送到人体内。

52. 发明授权

US5061274A Plug device for sealing openings and method of use 失效
标题翻译：用于密封开口的塞子装置和使用方法
公开(公告)号：US5061274A
公开(公告)日：1991-10-29
申请号：US445315
申请日：1989-12-04
申请人： Kenneth Kensey
发明人： Kenneth Kensey
IPC分类号： A61B17/00 , A61F2/06
CPC分类号： A61B17/0057 , A61B2017/00004 , A61F2/06
摘要： An instrument and methods of making and use for sealing a small, e.g., percutaneous, incisions or punctures. The instrument in the form of a tubular member having a plug therein. The tubular member includes a proximally located piston and a distally located portion having an open free end for introduction into the incision or puncture. The plug comprises a cord and a thin filament, with the cord being formed of a resorbable material and being folded in two to form an apex portion and a pair of wing portions extending therefrom. The filament is secured to the apex portion. The plug is located within the tubular member so that the apex portion is disposed adjacent the free end and with the wing portions and the filament extending toward the proximally located portion. The plug is then expelled partially from the tubular member so that the apex portion extends through the incision or puncture. The filament is then drawn proximally direction to pull the apex portion into engagement with the free end of the tubular member to expand the apex portion to form a head having a tissue engagement surface. The plug is then drawn back through the incision or puncture so that the tissue engagement surface intimately engages the tissue contiguous with the incision or puncture.
摘要翻译：用于密封小例如经皮切口或穿刺的制造和使用的仪器和方法。管状构件的形式的仪器具有插头。管状构件包括近端定位的活塞和具有用于引入切口或穿刺的开放自由端的远侧定位部分。塞子包括绳索和细长丝，绳索由可再吸收的材料形成并且被折叠成两个以形成从其延伸的顶点部分和一对翼部分。灯丝被固定到顶点部分。塞子位于管状构件内，使得顶部部分邻近自由端设置，并且翼部分和细丝朝近端定位的部分延伸。然后塞子部分地从管状部件排出，使得顶点部分延伸穿过切口或穿刺。然后将丝线向近侧拉伸以拉动顶点部分与管状构件的自由端接合，以使顶部部分膨胀以形成具有组织接合表面的头部。然后通过切口或穿刺将塞子拉回，使得组织接合表面紧密地接合与切口或穿刺相邻的组织。

53. 发明授权

US4890612A Device for sealing percutaneous puncture in a vessel 失效
标题翻译：用于密封容器中经皮穿刺的装置
公开(公告)号：US4890612A
公开(公告)日：1990-01-02
申请号：US194641
申请日：1988-05-16
申请人： Kenneth Kensey
发明人： Kenneth Kensey
IPC分类号： A61B17/00 , A61B17/04 , A61B17/12 , A61F2/00 , A61F2/02 , A61F2/04 , A61F2/06 , A61F2/24
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00243 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61F2/04 , A61F2/06 , A61F2002/30062 , A61F2002/30075 , A61F2210/0004 , A61F2210/0061
摘要： A device and method for sealing a puncture or incision formed percutaneously in tissue separating two internal portions of the body of a living being, e.g., a puncture or incision in an artery, in the gall bladder, in the liver, in the heart, etc. The device comprises plug means having a holding portion which is adapted to engage portions of the tissue adjacent the puncture or incision to hold the plug means in place and a sealing portion formed of a foam material and extending through the puncture or incision to engage the tissue contiguous therewith to seal the puncture or incision from the flow of body fluid therethrough. In the preferred embodiment, the closure or plug means is formed of a biodegradable material.
摘要翻译：一种用于密封穿孔的切口或切口的装置，其用于将生物体的两个内部部分（例如动脉中的穿刺或切口，胆囊，肝脏，心脏等）分离出来该装置包括具有保持部分的塞子装置，该保持部分适于接合穿刺或切口附近的组织部分，以将塞子装置保持在适当的位置，以及由泡沫材料形成并延伸穿过穿刺或切口以使其接合的密封部分与其相邻的组织以密封穿刺或切开体液的穿透。在优选实施例中，封闭或插塞装置由可生物降解的材料形成。

54. 发明授权

US4753221A Blood pumping catheter and method of use 失效
标题翻译：抽血导管及使用方法
公开(公告)号：US4753221A
公开(公告)日：1988-06-28
申请号：US921987
申请日：1986-10-22
申请人： Kenneth Kensey , John Nash
发明人： Kenneth Kensey , John Nash
IPC分类号： A61M1/10 , A61M1/12 , A61M25/00 , A61M1/03
CPC分类号： A61M1/101 , A61M1/1024 , A61M1/1034 , A61M1/125 , A61M25/00 , Y10S415/90
摘要： An elongated catheter for pumping blood through at least a portion of a being's vascular system. The catheter is of sufficiently small diameter and flexiblility to enable it to be passed through the vascular system so that the distal end portion of the catheter is located within or adjacent the being' heart. A rotatable pump is located at the distal end of the catheter and is rotated by drive means in the catheter. The distal end portion of the catheter includes an inlet for blood to flow therein and an outlet for blood to flow thereout. The catheter is arranged so that blood is pumped by the catheter's pump through the heart and into the vascular system without requiring any pumping action of the heart.
摘要翻译：用于通过血管系统的至少一部分泵送血液的细长导管。导管具有足够小的直径和柔韧性，以使其能够通过血管系统，使得导管的远端部分位于心脏内或邻近心脏。可旋转泵位于导管的远端，并通过导管中的驱动装置旋转。导管的远端部分包括用于血液流入的入口和用于血液流出的出口。导管布置成使得血液被导管的泵泵送通过心脏并进入血管系统，而不需要心脏的任何泵送作用。

55. 发明授权

US4744364A Device for sealing percutaneous puncture in a vessel 失效
标题翻译：用于密封容器中经皮穿刺的装置
公开(公告)号：US4744364A
公开(公告)日：1988-05-17
申请号：US15267
申请日：1987-02-17
申请人： Kenneth Kensey
发明人： Kenneth Kensey
IPC分类号： A61B17/00 , A61B17/12 , A61F2/00 , A61F2/06 , A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00659 , A61F2/06 , A61F2002/30075 , A61F2210/0061
摘要： A device for sealing an opening or puncture in the wall of a blood vessel, duct or other lumen of a living being. The device includes an elongated tubular body having an outlet at the distal end thereof and which is arranged to be inserted, such as percutaneously, through the puncture in the blood vessel so that the outlet is located within the vessel's interior. An expandible closure is disposed within the tubular body and is formed so as to be held in a compact configuration therein. The tubular body also includes ejecting means for forcing the closure out of the outlet into the interior of the blood vessel, whereupon the closure automatically expands to form an enlarged engagement surface. A retraction filament is secured to the closure for pulling it to the puncture after the tubular body has been withdrawn from the puncture so that the engagement surface of the closure means hemostatically engages the inner surface of the blood vessel contiguous with the puncture. The filament held taut and taped or otherwise secured in place on the patient's skin to hold the closure in position. The closure and filament are each formed of a biodegradable material to enable the closure to be left in place. Preferably the closure also includes a non-thrombogenic coating on its surface. The closure is constructed so that when it is opened and is in place sealing the puncture in the blood vessel it doesn't appreciably block the flow of any blood through the blood vessel.
摘要翻译：一种用于密封活体的血管，管道或其他内腔的壁中的开口或穿刺的装置。该装置包括细长的管状体，其具有在其远端处的出口，并且其布置成通过血管中的穿刺被插入，例如经皮，使得出口位于血管内部。可膨胀的封闭件设置在管状体内并形成为保持在其中的紧凑结构。管状体还包括用于迫使封闭件从出口进入血管内部的排出装置，于是闭合件自动膨胀以形成扩大的接合表面。在管状体已经从穿刺抽出之后，缩回丝固定到封闭件上以将其拉出到穿刺部上，使得封闭装置的接合表面与穿刺连接的血管内表面进行止血。细丝被拉紧并贴上或以其他方式固定在患者皮肤上的适当位置以将封闭物保持在适当位置。封闭件和细丝均由可生物降解的材料形成，以使封闭件能够保持在适当的位置。优选地，闭合件还包括其表面上的非血栓形成的涂层。闭合件被构造成使得当它被打开并且在其中的位置密封血管中的穿刺时，其不会明显地阻止任何血液通过血管的流动。

56. 发明授权

US4679558A Catheter based surgical methods and apparatus therefor 失效
公开(公告)号：US4679558A
公开(公告)日：1987-07-14
申请号：US909802
申请日：1986-09-22
申请人： Kenneth Kensey , John Nash
发明人： Kenneth Kensey , John Nash
IPC分类号： A61B17/22 , A61B17/32 , A61B17/00
CPC分类号： A61B17/320758 , A61B2017/22097 , A61B2017/320044
摘要： Methods for effecting various surgical procedures via the use of a flexible, small diameter, catheter. The catheter includes a working head arranged to be moved, e.g., rotated, at a high rate of speed by an associated drive system. In one method the catheter with the moving head is brought into engagement with a restriction caused by an atherosclerotic deposit in an artery to effect the opening of the restriction by the dilation of the artery. In another method the catheter is used to dilate a duct or tube, e.g., a fallopian tube, eustachian tube, bile duct, etc. in a living being. In another application the catheter is used to effect the in situ valvulectomy of a section of vein within a living being. In still another method the catheter is used to disintegrate a stone, such as a kidney or gall stone, in the body of a living being. In yet another method, the catheter is used to stop spasm in a lumen in a living being. A catheter is also disclosed which is particularly configured to effect an in situ valvulectomy or stone disintegration procedure.

57. 发明授权

US06443911B1 Viscosity measuring apparatus and method of use 失效
标题翻译：粘度测量装置及其使用方法
公开(公告)号：US06443911B1
公开(公告)日：2002-09-03
申请号：US09629216
申请日：2000-07-31
申请人： Kenneth Kensey , John E. Nash
发明人： Kenneth Kensey , John E. Nash
IPC分类号： A61B500
CPC分类号： A61B5/150786 , A61B5/02035 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150755 , A61B5/150992 , A61B5/155 , A61B5/157 , A61B5/6866 , G01N11/04 , G01N11/08 , G06F19/00
摘要： A blood viscosity measuring system and method that monitors the rising head of a column of fluid representing a living being's blood in-vivo to determine the blood viscosity over a range of shears. The system includes a capillary tube, at least a portion of which is located within the vascular system of the being, and a riser tube, having a liquid therein coupled to the capillary tube. A sensor and associated microprocessor are provided to determine the change in the height of the liquid in the riser tube at plural points along the length of the tube from which the viscosity is calculated.
摘要翻译：一种血液粘度测量系统和方法，其在体内监测表示活体血液的一列流体的上升头，以确定剪切范围内的血液粘度。该系统包括毛细管，其毛细管的至少一部分位于血管系统的内部，以及提升管，其中具有联接到毛细管的液体。提供传感器和相关的微处理器以确定沿着管的长度的多个点处的提升管中液体的高度的变化，其中计算粘度。

58. 发明授权

US06179863B2 Hemostatic puncture closure system and method of use 失效
公开(公告)号：US06179863B2
公开(公告)日：2001-01-30
申请号：US09294154
申请日：1999-04-19
申请人： Kenneth Kensey , John Nash , Douglas Evans
发明人： Kenneth Kensey , John Nash , Douglas Evans
IPC分类号： A61B1708
CPC分类号： A61B17/0057 , A61B90/03 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672 , A61B2017/00898 , A61B2017/0496 , A61B2090/032 , A61B2090/0811 , F16G11/108 , Y10S604/90
摘要： A system, a closure, and method of use for sealing a percutaneous puncture in a blood vessel. The puncture includes an opening in the vessel wall and a tract leading to the opening. The system includes an introducer sheath and associated positioning device, a hemostatic puncture closure, and a deployment instrument. The positioning device enables the introducer sheath to be positioned at a desired position within the vessel. The deployment instrument includes a tubular carrier storing the closure. The closure comprises a rigid, e.g., radio-opaque, anchor, a compressed collagen plug, and a thin filament connecting the two in a pulley-like arrangement. The instrument and introducer are used to introduce the closure into the puncture, with the anchor located within the artery and with the collagen plug within the puncture tract. A locking member is provided to hold the closure in place at its operative position, whereupon hemostasis occurs rapidly, thereby sealing the puncture.

59. 发明授权

US6090130A Hemostatic puncture closure system including blood vessel locator and method of use 失效
标题翻译：止血性穿刺闭合系统，包括血管定位器和使用方法
公开(公告)号：US6090130A
公开(公告)日：2000-07-18
申请号：US104321
申请日：1998-06-25
申请人： John E. Nash , Douglas G. Evans , Kenneth Kensey
发明人： John E. Nash , Douglas G. Evans , Kenneth Kensey
IPC分类号： A61B17/00 , A61B17/04 , A61B17/12 , A61B19/00 , F16G11/04 , F16G11/10 , A61B17/08
CPC分类号： A61B17/0057 , F16G11/108 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672 , A61B2017/0496 , A61B2090/032 , A61B2090/0811 , A61B90/03 , A61B90/39 , Y10S604/90
摘要： A system for sealing a percutaneous puncture in a blood vessel in a living being and method of use thereof. The system includes a hemostatic closure, a blood vessel locator device for determining the position of the blood vessel via the percutaneous puncture, and a deployment instrument for deploying the closure within the puncture to seal the puncture. The vessel locator includes means for enabling blood from the vessel to flow therethrough so that the position of the vessel can be rapidly determined. Once the vessel has been located the deployment instrument, which includes a tubular carrier storing the closure, is extended into the puncture to deploy the closure. The closure basically comprises a radiopaque rigid anchor for location within the blood vessel, a compressed collagen plug for location within the puncture tract leading to the vessel, and a thin filament connecting the two in a pulley-like arrangement. The deployment instrument also includes a tamper which is used to mechanically deform the plug within the tract. Once the closure is positioned hemostasis occurs rapidly, thereby locking the closure in place.
摘要翻译：一种用于密封生物体内的血管中的经皮穿刺的系统及其使用方法。该系统包括止血闭合件，用于通过经皮穿刺确定血管位置的血管定位器装置，以及用于在穿刺部内展开封闭物以密封穿刺的展开装置。容器定位器包括用于使来自血管的血液流过其中的装置，使得能够快速确定容器的位置。一旦容器已经定位，包括容纳封闭件的管状载体的展开器械延伸到穿刺部分中以展开闭合件。闭合件基本上包括用于定位在血管内的不透射线的刚性锚固件，用于定位在穿过血管的穿刺道内的压缩胶原塞，以及以滑轮状布置连接两者的细丝。部署仪器还包括用于将管塞内的插头机械地变形的篡改。一旦闭合物被定位，止血就快速发生，从而将闭合件锁定就位。

60. 发明授权

US5676689A Hemostatic puncture closure system including vessel location device and method of use 失效
标题翻译：止血穿刺闭合系统，包括血管位置装置和使用方法
公开(公告)号：US5676689A
公开(公告)日：1997-10-14
申请号：US608428
申请日：1996-02-28
申请人： Kenneth Kensey , John Nash , Douglas Evans
发明人： Kenneth Kensey , John Nash , Douglas Evans
IPC分类号： A61B17/00 , A61B17/04 , A61B17/12 , A61B19/00 , F16G11/04 , F16G11/10
CPC分类号： A61B17/0057 , F16G11/108 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672 , A61B2017/0496 , A61B2090/032 , A61B2090/0811 , A61B90/03 , A61B90/39 , Y10S604/90
摘要： A system for sealing a percutaneous puncture in a blood vessel in a living being and method of use thereof. The system includes a hemostatic closure, a blood vessel locator device for determining the position of the blood vessel via the percutaneous puncture, and a deployment instrument for deploying the closure within the puncture to seal the puncture. The vessel locator includes means for enabling blood from the vessel to flow therethrough so that the position of the vessel can be rapidly determined. Once the vessel has been located the deployment instrument, which includes a tubular carrier storing the closure, is extend into the puncture to deploy the closure. The closure basically comprises a radiopaque rigid anchor for location within the blood vessel, a compressed collagen plug for location within the puncture tract leading to the vessel, and a thin filament connecting the two in a pulley-like arrangement. The deployment instrument also includes a tamper which is used to mechanically deform the plug within the tract. Once the closure is positioned hemostasis occurs rapidly, thereby locking the closure in place.
摘要翻译：一种用于密封生物体内的血管中的经皮穿刺的系统及其使用方法。该系统包括止血闭合件，用于通过经皮穿刺确定血管位置的血管定位装置，以及用于在穿刺部内展开封闭物以密封穿刺的展开装置。容器定位器包括用于使来自血管的血液流过其中的装置，使得能够快速确定容器的位置。一旦容器已经定位，包括容纳封闭件的管状载体的展开器械延伸到穿刺部分中以展开闭合件。闭合件基本上包括用于定位在血管内的不透射线的刚性锚固件，用于定位在穿过血管的穿刺道内的压缩胶原塞，以及以滑轮状布置连接两者的细丝。部署仪器还包括用于将管塞内的插头机械地变形的篡改。一旦闭合物被定位，止血就快速发生，从而将闭合件锁定就位。

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