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51. 发明授权

US08252816B2 Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions 失效
标题翻译：香草酸受体配体化合物，含有它们的药物组合物，其制备方法及其用于治疗疼痛和各种其它病症的用途
公开(公告)号：US08252816B2
公开(公告)日：2012-08-28
申请号：US12081174
申请日：2008-04-11
申请人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Jeewoo Lee
发明人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Jeewoo Lee
IPC分类号： A61K31/445 , C07D211/14
CPC分类号： C07D211/08 , C07C311/08 , C07C323/41 , C07C2601/14 , C07D211/14 , C07D213/70 , C07D401/04
摘要： Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical composition s containing such compounds, a method for producing the compounds, and the use of such compounds to treat pain and various other conditions.
摘要翻译：对应于式I的化合物：其作为香草素受体配体，含有这些化合物的药物组合物，制备化合物的方法，以及这些化合物用于治疗疼痛和各种其它病症的用途。

52. 发明申请

US20090137594A1 Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments 失效
标题翻译：五氟硫基取代的化合物及其用于生产药物的用途
公开(公告)号：US20090137594A1
公开(公告)日：2009-05-28
申请号：US11915023
申请日：2006-05-17
申请人： Robert Frank , Bernd Sundermann , Hans Schick
发明人： Robert Frank , Bernd Sundermann , Hans Schick
IPC分类号： A61K31/17 , C07C335/06 , C07D401/04 , C07D213/56 , C07D403/02 , C07C323/31 , A61K31/472 , A61K31/496 , A61K31/53 , A61K31/4418 , A61K31/4725 , A61K31/165 , C07D487/04 , C07D217/00 , C07C275/32 , A61P25/00
CPC分类号： C07C381/00
摘要： The present invention relates to pentafluorosulphanyl-substituted compounds, methods for their production, medicaments containing such compounds and the use of such compounds for producing medicaments.
摘要翻译：本发明涉及五氟硫基取代的化合物，其制备方法，含有这些化合物的药物以及这些化合物用于生产药物的用途。

53. 发明申请

US20060030939A1 Implantable prosthesis for positioning and supporting a breast implant 有权
公开(公告)号：US20060030939A1
公开(公告)日：2006-02-09
申请号：US11196217
申请日：2005-08-03
申请人： Robert Frank
发明人： Robert Frank
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61F2/0063
摘要： An implantable prosthesis for use in positioning a breast implant comprising a sheet of a prosthetic material configured to form a sling-shaped receiving area for receiving and supporting the breast implant. The surface area of the implantable prosthesis contacting the breast implant comprises a biocompatible or chemically inert material to prevent abrasion of or reaction with the breast implant. The implantable prosthesis of the present invention can be used during corrective procedures to reposition and support a malpositioned breast implant or during reconstructive or cosmetic procedures at the time the implant is first positioned within the patient. The prosthesis is used with implants in the partial sub-muscular, completely sub-muscular, and sub-glandular position and is used to prevent medial, lateral and inferior displacement of the implant.

54. 发明授权

US06585241B1 Device for the vibration-absorbing mounting of a compressed-air generator on a mounting support of a rail vehicle 有权
标题翻译：用于在轨道车辆的安装支架上的压缩空气发生器的吸震安装装置
公开(公告)号：US06585241B1
公开(公告)日：2003-07-01
申请号：US09869071
申请日：2001-07-05
申请人： Michael Hartl , Frank Meyer , Robert Frank , Markus Ehinger
发明人： Michael Hartl , Frank Meyer , Robert Frank , Markus Ehinger
IPC分类号： F16M700
CPC分类号： F16F7/14 , B61D49/00 , F16F3/10
摘要： A device for the vibration-absorbing mounting of a compressed-air generator including a first spring element which is mounted on a mounting support. A second spring element is provided on which the compressed-air generator is arranged. One of the two spring elements has a spring rigidity in essentially the vertical direction that is maximally half its spring rigidity in essentially the horizontal direction. The second spring element is arranged in series with the first-spring element. The inventive device reduces the acceleration measured at the bottom of the understructure to values which are at least 30% of the values known from the prior art.
摘要翻译：一种用于吸收压缩空气发生器的装置，包括安装在安装支架上的第一弹簧元件。设置有压缩空气发生器的第二弹簧元件。两个弹簧元件中的一个在基本上在垂直方向上具有弹簧刚度，其基本上在水平方向上的最大一半的弹簧刚度。第二弹簧元件与第一弹簧元件串联布置。本发明的装置将在底部底部测量的加速度降低至现有技术已知值的至少30％的值。

55. 发明授权

US3958357A Fish bait package 失效
标题翻译：鱼饵包装
公开(公告)号：US3958357A
公开(公告)日：1976-05-25
申请号：US552242
申请日：1975-02-24
申请人： Robert Frank
发明人： Robert Frank
IPC分类号： A01K85/00 , A01K97/04
CPC分类号： A01K85/00 , A01K97/045
摘要： A package for fish bait of the odor type commonly known as "dough bait" consisting of a hollow cylindrical tube of foraminous material adapted to contain the bait, and secured closed at both ends, said tube being adapted to be threaded over the point of a fishhook. The means securing at least one end of said tube may consist of a resiliently yieldable binding, whereby when the hook is inserted through said binding, it assists in securing and retaining the package on the hook.
摘要翻译：用于通常称为“面团诱饵”的气味类型的鱼饵的包装，其由适于容纳饵料的多孔材料的中空圆柱形管组成，并且在两端固定为闭合，所述管适于在鱼钩。固定所述管的至少一端的装置可以由弹性收缩的装订组成，由此当钩穿过所述装订时，其有助于将包装固定并保持在钩上。

56. 发明授权

US08791268B2 Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions 有权
公开(公告)号：US08791268B2
公开(公告)日：2014-07-29
申请号：US13077452
申请日：2011-03-31
申请人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jeewoo Lee
发明人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jeewoo Lee
IPC分类号： A61K31/44 , C07D213/62
CPC分类号： C07D213/74 , C07D213/64 , C07D213/70
摘要： Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.

57. 发明授权

US08785474B2 Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions 失效
标题翻译：香草素受体配体，含有它们的药物组合物，制备它们的方法及其用途来治疗疼痛和其它病症
公开(公告)号：US08785474B2
公开(公告)日：2014-07-22
申请号：US13210719
申请日：2011-08-16
申请人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Bernd Sundermann , Jeewoo Lee
发明人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Bernd Sundermann , Jeewoo Lee
IPC分类号： C07D401/12 , C07D401/14 , A61K31/4709 , A61K31/4725
CPC分类号： C07D235/24 , C07D241/40 , C07D263/54 , C07D265/36 , C07D401/04
摘要： Vanilloid receptor ligand compounds corresponding to formula I: pharmaceutical compositions containing such compounds, a process for producing such compounds, and methods of using such compounds for treating or inhibiting pain and various other disorders or conditions.
摘要翻译：对应于式I的香草酸受体配体化合物：含有这些化合物的药物组合物，制备这些化合物的方法，以及使用这些化合物治疗或抑制疼痛和各种其它疾病或病症的方法。

58. 发明授权

US08710233B2 Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations 失效
标题翻译：香草素受体配体及其用于制备药物制剂的用途
公开(公告)号：US08710233B2
公开(公告)日：2014-04-29
申请号：US11551060
申请日：2006-10-19
申请人： Jeewoo Lee , Hyung Chul Ryu , Robert Frank , Gregor Bahrenberg , Jean De Vry , Thomas Christoph , Derek John Saunders , Klaus Schiene , Bernd Sundermann
发明人： Jeewoo Lee , Hyung Chul Ryu , Robert Frank , Gregor Bahrenberg , Jean De Vry , Thomas Christoph , Derek John Saunders , Klaus Schiene , Bernd Sundermann
IPC分类号： C07D213/40 , A61K31/44
CPC分类号： C07D409/04 , C07C311/08 , C07C2601/08 , C07C2601/14 , C07D211/14 , C07D211/18 , C07D213/40 , C07D213/64 , C07D213/70 , C07D213/74 , C07D213/81 , C07D213/83 , C07D223/04 , C07D225/02 , C07D295/135 , C07D401/04 , C07D401/12 , C07D401/14 , C07D413/04
摘要： The present invention relates to novel vanilloid receptor ligands, to a process for the production thereof, to pharmaceutical preparations containing these compounds and to the use of these compounds for the production of pharmaceutical preparations.
摘要翻译：本发明涉及新型香草酸受体配体，其制备方法，含有这些化合物的药物制剂以及这些化合物用于制备药物制剂的用途。

59. 发明授权

US08592471B2 Substituted phenylureas and phenylamides as vanilloid receptor ligands 有权
公开(公告)号：US08592471B2
公开(公告)日：2013-11-26
申请号：US12775235
申请日：2010-05-06
申请人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Nils Damann , Sven Frormann , Bernhard Lesch , Jeewoo Lee , Yong-Soo Kim , Myeong-Seop Kim , Derek Saunders , Hannelore Stockhausen
发明人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Nils Damann , Sven Frormann , Bernhard Lesch , Jeewoo Lee , Yong-Soo Kim , Myeong-Seop Kim , Derek Saunders , Hannelore Stockhausen
IPC分类号： A61K31/41 , C07D231/12
CPC分类号： C07D231/12 , C07D249/08 , C07D401/04 , C07D405/06 , C07D417/06
摘要： The invention relates to substituted phenylureas and phenylamides, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions.

60. 发明申请

US20110301156A1 Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof to Treat Pain and Other Conditions 失效
标题翻译：香草素受体配体，含有它们的药物组合物及其制备方法及其用途来治疗疼痛及其他病症
公开(公告)号：US20110301156A1
公开(公告)日：2011-12-08
申请号：US13210719
申请日：2011-08-16
申请人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Bernd Sundermann , Jeewoo Lee
发明人： Robert Frank , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Bernd Sundermann , Jeewoo Lee
IPC分类号： A61K31/538 , A61K31/423 , C07D235/26 , A61K31/4184 , C07D265/36 , C07D319/18 , A61K31/352 , C07D235/28 , C07D241/42 , A61K31/498 , C07D401/14 , A61K31/4545 , C07D263/58 , C07D215/14 , A61K31/47 , C07D401/12 , A61K31/4439 , C07D417/14 , C07D413/14 , A61P29/00 , A61P25/06 , A61P25/00 , A61P25/04 , A61P25/28 , A61P25/24 , A61P25/08 , A61P25/16 , A61P11/00 , A61P13/00 , A61P1/00 , A61P1/04 , A61P13/10 , A61P27/02 , A61P17/00 , A61P17/06 , A61P1/12 , A61P19/10 , A61P17/04 , A61P3/00 , A61P25/32 , A61P25/30 , A61P9/00 , A61P17/02 , A61P11/06 , C07D263/56
CPC分类号： C07D235/24 , C07D241/40 , C07D263/54 , C07D265/36 , C07D401/04
摘要： Vanilloid receptor ligand compounds corresponding to formula I: pharmaceutical compositions containing such compounds, a process for producing such compounds, and methods of using such compounds for treating or inhibiting pain and various other disorders or conditions.
摘要翻译：对应于式I的香草酸受体配体化合物：含有这些化合物的药物组合物，制备这些化合物的方法，以及使用这些化合物治疗或抑制疼痛和各种其它疾病或病症的方法。

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