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51. 发明申请

US20110295286A1 METHODS AND DEVICES FOR REGULATING THE ACTIVATION OF GHRELIN HORMONES WITHIN A STOMACH 有权
标题翻译：调节GHRELIN HORMONES在STOMACH中激活的方法和装置
公开(公告)号：US20110295286A1
公开(公告)日：2011-12-01
申请号：US13105006
申请日：2011-05-11
申请人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
发明人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
IPC分类号： A61B17/11
CPC分类号： A61F5/0076 , A61B2017/0404 , A61F5/0083
摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.
摘要翻译：方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

52. 发明申请

US20110295179A1 METHODS AND DEVICES FOR REGULATING THE ACTIVATION OF GHRELIN HORMONES WITHIN A STOMACH 审中-公开
公开(公告)号：US20110295179A1
公开(公告)日：2011-12-01
申请号：US13105014
申请日：2011-05-11
申请人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
发明人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
IPC分类号： A61M5/00
CPC分类号： A61F5/0083 , A61F5/0076
摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.

53. 发明授权

US08585628B2 Methods and devices for regulating the activation of ghrelin hormones within a stomach 有权
标题翻译：调节胃内生长素释放激素激活的方法和装置
公开(公告)号：US08585628B2
公开(公告)日：2013-11-19
申请号：US13105006
申请日：2011-05-11
申请人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
发明人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
IPC分类号： A61B19/00
CPC分类号： A61F5/0076 , A61B2017/0404 , A61F5/0083
摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.
摘要翻译：方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

54. 发明授权

US07445622B2 Anastomotic ring applier with double motion actuation 有权
标题翻译：具有双动作动作的吻合环施加器
公开(公告)号：US07445622B2
公开(公告)日：2008-11-04
申请号：US11122349
申请日：2005-05-05
申请人： Mark S. Ortiz , Eugene L. Timperman
发明人： Mark S. Ortiz , Eugene L. Timperman
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/1114 , A61B17/08 , A61B17/115 , A61B2017/00367 , A61B2017/00867 , A61B2017/0408 , A61B2017/2923
摘要： A surgical tool for deploying an anastomotic ring comprises a handle and a ring deployment mechanism at the distal end of a shaft. The ring deployment mechanism has a distal portion and a proximal portion, and is moveable from an unactuated position to an actuated position to deploy an anastomotic ring. To prevent tissue from becoming trapped in the deployment mechanism during insertion or extraction of the tool, distal and proximal sheaths are configured to cover distal and proximal portions of the ring deployment mechanism, respectively. An actuation mechanism in the handle permits advancement of the distal sheath and actuation of the distal portion of the ring deployment mechanism with a single movement of a first actuator slider. The actuation mechanism also permits retraction of the proximal sheath and actuation of the proximal portion of the ring deployment mechanism with a single movement of a second actuator slider.
摘要翻译：用于展开吻合环的手术工具包括在轴的远端处的手柄和环展开机构。环展开机构具有远侧部分和近端部分，并且可从未致动位置移动到致动位置以展开吻合环。为了防止组织在插入或拔出工具期间被捕获在展开机构中，远端和近侧护套分别被构造成覆盖环展开机构的远侧和近端部分。手柄中的致动机构允许使用第一致动器滑块的单个运动使远端护套的前进和环形展开机构的远端部分的致动。致动机构还允许第二致动器滑块的单个运动来近端护套的缩回和环形展开机构的近侧部分的致动。

55. 发明申请

US20080110958A1 Disposable Cartridge With Adhesive For Use With A Stapling Device 有权
标题翻译：一次性胶带与粘合剂一起用于装订装置
公开(公告)号：US20080110958A1
公开(公告)日：2008-05-15
申请号：US11558524
申请日：2006-11-10
申请人： Robert H. McKenna , Frederick E. Shelton , Randal T. Byrum , Mark S. Ortiz , Paul J. Conrad , Eugene L. Timperman
发明人： Robert H. McKenna , Frederick E. Shelton , Randal T. Byrum , Mark S. Ortiz , Paul J. Conrad , Eugene L. Timperman
IPC分类号： A61B17/10
CPC分类号： A61B17/07207 , A61B17/00491 , A61B2017/07214 , A61B2017/2943 , A61B2017/320052
摘要： A surgical stapling device is provided for clamping and stapling tissue, and for dispensing a fluid such as an adhesive onto the tissue. The adhesive can be stored within one or more rigid chambers within removable cartridge and dispensed from a plurality of passageways within the cartridge. A plurality of staples and staple drivers are located in the cartridge and may be isolated from the fluid. Both linear and rotary members can be provided to dispense the fluid from the cartridge. Alternately, the fluid can be dispensed from the cartridge at any time with an operator actuatable control. A removable staple cartridge cover can be provided to seal the fluid in the cartridge and prevent fluid loss. Alternately, a fluid cartridge can be provided that can mount within a surgical stapling device and dispense one or more firings of a fluid therefrom.
摘要翻译：提供外科缝合装置用于夹紧和缝合组织，并用于将诸如粘合剂的流体分配到组织上。粘合剂可以存储在可移除的盒中的一个或多个刚性室内并且从盒内的多个通道分配。多个订书针和订书钉驱动器位于盒中并且可以与流体隔离。可以提供线性和旋转构件，以便从筒中分配流体。或者，可以随时用操作者可控制的控制从盒中分配流体。可以提供可移除的钉仓盖以密封墨盒中的流体并防止流体损失。或者，可以提供流体盒，其可以安装在外科缝合装置内并从其中分配一个或多个流体的喷射。

56. 发明授权

US07721930B2 Disposable cartridge with adhesive for use with a stapling device 有权
标题翻译：具有粘合剂的一次性胶囊用于装订装置
公开(公告)号：US07721930B2
公开(公告)日：2010-05-25
申请号：US11558524
申请日：2006-11-10
申请人： Robert H. McKenna , Frederick E. Shelton, IV , Randal T. Byrum , Mark S. Ortiz , Paul J. Conrad , Eugene L. Timperman
发明人： Robert H. McKenna , Frederick E. Shelton, IV , Randal T. Byrum , Mark S. Ortiz , Paul J. Conrad , Eugene L. Timperman
IPC分类号： A61B17/072
CPC分类号： A61B17/07207 , A61B17/00491 , A61B2017/07214 , A61B2017/2943 , A61B2017/320052
摘要： A surgical stapling device is provided for clamping and stapling tissue, and for dispensing a fluid such as an adhesive onto the tissue. The adhesive can be stored within one or more rigid chambers within removable cartridge and dispensed from a plurality of passageways within the cartridge. A plurality of staples and staple drivers are located in the cartridge and may be isolated from the fluid. Both linear and rotary members can be provided to dispense the fluid from the cartridge. Alternately, the fluid can be dispensed from the cartridge at any time with an operator actuatable control. A removable staple cartridge cover can be provided to seal the fluid in the cartridge and prevent fluid loss. Alternately, a fluid cartridge can be provided that can mount within a surgical stapling device and dispense one or more firings of a fluid therefrom.
摘要翻译：提供外科缝合装置用于夹紧和缝合组织，并用于将诸如粘合剂的流体分配到组织上。粘合剂可以存储在可移除的盒中的一个或多个刚性室内并且从盒内的多个通道分配。多个订书针和订书钉驱动器位于盒中并且可以与流体隔离。可以提供线性和旋转构件，以便从筒中分配流体。或者，可以随时用操作者可控制的控制从盒中分配流体。可以提供可移除的钉仓盖以密封墨盒中的流体并防止流体损失。或者，可以提供可以安装在外科缝合装置内并且从其分配一个或多个流体的液体的流体盒。

57. 发明授权

US07691113B2 Screw tip control for anastomotic ring applier 有权
标题翻译：用于吻合环施加器的螺旋尖端控制
公开(公告)号：US07691113B2
公开(公告)日：2010-04-06
申请号：US11122383
申请日：2005-05-05
申请人： Mark S. Ortiz , Eugene L. Timperman
发明人： Mark S. Ortiz , Eugene L. Timperman
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/11 , A61B17/1114
摘要： A surgical instrument for applying an anastomotic ring device comprises a handle connected to an anastomotic ring deployment mechanism by a shaft. The shaft has at least one torsion member that is capable of communicating a torsional actuating force from the handle to the ring deployment mechanism. The ring deployment mechanism is configured to actuate in response to torsional actuating force communicated from the torsion member. A threaded shaft or rod may be positioned in the ring deployment mechanism to effect actuation of the ring deployment mechanism in response to torsion.
摘要翻译：用于施加吻合口装置的手术器械包括通过轴连接到吻合环展开机构的手柄。轴具有至少一个扭转构件，其能够将来自手柄的扭转致动力传递到环形展开机构。环形展开机构构造成响应于从扭转构件传递的扭转致动力来致动。螺纹轴或杆可以定位在环展开机构中，以响应于扭转来实现环展开机构的致动。

58. 发明授权

US08758405B2 Suture tensioning device 有权
标题翻译：缝线张紧装置
公开(公告)号：US08758405B2
公开(公告)日：2014-06-24
申请号：US11277334
申请日：2006-03-23
申请人： Mark S. Zeiner , Mark S. Ortiz
发明人： Mark S. Zeiner , Mark S. Ortiz
IPC分类号： A61B17/04
CPC分类号： A61B17/04 , A61B17/0483 , A61B17/0487 , A61B2017/0445 , A61B2017/0454 , A61B2017/0488 , A61B2017/0496
摘要： The present invention generally provides devices and methods for tensioning a length of suture. In one embodiment, a suture tensioning device is provided having a shaft and a suture grasping member. A knotting element can be removably coupled to a distal end of the shaft, and it can be adapted to receive a suture and to lock to engage the suture. The suture grasping member can be movably coupled to the shaft and configured to grasp a suture and pull it through the knotting element to allow the knotting element to lock and engage the suture.
摘要翻译：本发明通常提供用于张紧一段缝合线的装置和方法。在一个实施例中，提供了具有轴和缝合线抓持构件的缝合线张紧装置。打结元件可以可移除地联接到轴的远端，并且其可以适于接收缝合线并锁定以接合缝合线。缝线抓持构件可以可移动地联接到轴并且构造成抓住缝合线并将其拉过打结元件以允许打结元件锁定并接合缝合线。

59. 发明授权

US09750660B2 Devices and methods for the treatment of metabolic disorders 有权
公开(公告)号：US09750660B2
公开(公告)日：2017-09-05
申请号：US13825452
申请日：2012-03-30
申请人： Kevin D. Felder , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo , Mark S. Zeiner
发明人： Kevin D. Felder , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo , Mark S. Zeiner
IPC分类号： A61H9/00 , A61H23/00 , A61F5/00
CPC分类号： A61H23/00 , A61F5/004 , A61F5/0053 , A61F5/0063 , A61F5/0076 , A61F5/0079
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1) having a tissue engaging portion (2) intended to be placed in contact with a target tissue (3) of a gastrointestinal system of the subject, a movement device (15) linked with the tissue engaging portion (2) and operable to move the tissue engaging portion (2), thereby mechanically stimulating the target tissue (3), and an anchoring device for permanently fastening the stimulus device (1) in a target location at the gastrointestinal system such that the tissue engaging portion (2) engages the target tissue (3).

60. 发明申请

US20150011919A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 有权
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：US20150011919A1
公开(公告)日：2015-01-08
申请号：US13825452
申请日：2012-03-30
申请人： Kevin D. Felder , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo , Mark S. Zeiner
发明人： Kevin D. Felder , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo , Mark S. Zeiner
IPC分类号： A61H23/00
CPC分类号： A61H23/00 , A61F5/004 , A61F5/0053 , A61F5/0063 , A61F5/0076 , A61F5/0079
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1) having a tissue engaging portion (2) intended to be placed in contact with a target tissue (3) of a gastrointestinal system of the subject, a movement device (15) linked with the tissue engaging portion (2) and operable to move the tissue engaging portion (2), thereby mechanically stimulating the target tissue (3), and an anchoring device for permanently fastening the stimulus device (1) in a target location at the gastrointestinal system such that the tissue engaging portion (2) engages the target tissue (3).
摘要翻译：用于刺激受试者的饱腹感激素释放的系统包括具有组织接合部分（2）的刺激装置（1），所述组织接合部分（2）旨在与受试者的胃肠系统的靶组织（3）接触，装置（15），其与组织接合部分（2）连接并且可操作以移动组织接合部分（2），从而机械刺激目标组织（3），以及用于将激励装置（1）永久固定在目标位置在胃肠系统，使得组织接合部分（2）接合目标组织（3）。

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