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51. 发明申请

US20060119920A1 High speed, high efficiency optical pattern generator using rotating optical elements 有权
公开(公告)号：US20060119920A1
公开(公告)日：2006-06-08
申请号：US11339097
申请日：2006-01-24
申请人： Leonard DeBenedictis , C. Nabors , George Frangineas
发明人： Leonard DeBenedictis , C. Nabors , George Frangineas
IPC分类号： G02B26/08
CPC分类号： G02B26/105 , G02B13/0095 , G02B26/0875 , G02B26/10 , G02B27/30 , Y10S359/90
摘要： An optical pattern generator includes one or more multi-faceted rotating optical elements that introduce an offset that is rotation insensitive. The component that generates the offset is rotationally symmetric around the rotational axis of the optical element. Thus, as the optical element rotates, the effect of the offset component does not change. In addition, rotating optical elements may be designed to counteract unwanted optical effects of each other.

52. 发明申请

US20050259306A1 Two-dimensional optical scan system using a counter-rotating disk scanner 有权
标题翻译：二维光学扫描系统采用反向旋转扫描仪
公开(公告)号：US20050259306A1
公开(公告)日：2005-11-24
申请号：US10914860
申请日：2004-08-09
申请人： Barry Broome , George Frangineas , Leonard DeBenedictis
发明人： Barry Broome , George Frangineas , Leonard DeBenedictis
IPC分类号： G02B26/08 , G02B26/10 , G02B26/12
CPC分类号： G02B26/106 , G02B26/0875 , G02B26/10 , G03B21/14
摘要： A counter-rotating disk scanner together with another scan mechanism provides two-dimensional optical scanning. The counter-rotating disk scanner includes counter-rotating scan disks that implement the scanning action as they rotate through an optical axis of the system.
摘要翻译：反向旋转磁盘扫描器与另一扫描机构一起提供二维光学扫描。反向旋转盘扫描器包括反向旋转的扫描盘，当它们旋转通过系统的光轴时，其执行扫描动作。

53. 发明授权

US6130900A Pulsed intracavity frequency-converted solid-state laser with long-pulse simulation 有权
标题翻译：脉冲腔内频率转换固态激光器与长脉冲模拟
公开(公告)号：US6130900A
公开(公告)日：2000-10-10
申请号：US263338
申请日：1999-03-05
申请人： John F. Black , George Frangineas , Hartmuth Hecht
发明人： John F. Black , George Frangineas , Hartmuth Hecht
IPC分类号： A61B18/20 , H01S3/108 , H01S3/109 , H01S3/10
CPC分类号： H01S3/108 , A61B18/203 , A61B2018/00452 , H01S3/1083 , H01S3/109
摘要： In an intracavity frequency-converted pulsed laser, output-pulses having a duration longer than three milliseconds are simulated by a burst of temporally spaced-apart pulses having a shorter duration, the burst duration being about equal to the duration of the pulse being simulated. In an example of the laser including a KTP crystal providing frequency-doubling and having an Nd:YAG gain-medium for providing fundamental radiation at a wavelength of 1064 nm, a thin-etalon having a thickness of about 75 micrometers is included in the laser cavity to suppress generation of laser-radiation at wavelengths of 1061 and 1074 nm. Suppression of oscillation at these wavelengths prevents damage in the KTP crystal due to abrupt intracavity power surges thereby preventing damage to the KTP crystal. Examples of intracavity-pumped optical parametric oscillators including a thin etalon and operated in a similar manner are also disclosed.
摘要翻译：在腔内频率转换的脉冲激光器中，具有长于三毫秒的持续时间的输出脉冲由具有较短持续时间的时间间隔脉冲的脉冲串来模拟，脉冲串持续时间大约等于被模拟的脉冲的持续时间。在包括提供倍频并且具有用于提供1064nm波长的基本辐射的Nd：YAG增益介质的激光器的实例中，激光器包括厚度为约75微米的薄标准具以抑制波长为1061和1074nm的激光辐射的产生。抑制这些波长的振荡可防止KTP晶体由于突发性腔内功率浪涌而造成的损坏，从而防止对KTP晶体的损坏。还公开了包括精密标准具并以类似方式操作的腔内泵浦光学参量振荡器的实例。

54. 发明授权

US08289602B2 Optical pattern generator using multiple reflective surfaces 失效
公开(公告)号：US08289602B2
公开(公告)日：2012-10-16
申请号：US13334799
申请日：2011-12-22
申请人： George Frangineas
发明人： George Frangineas
IPC分类号： G02B26/08 , G02B26/10 , G02B26/12
CPC分类号： G02B26/129
摘要： An optical pattern generator uses reflection from multiple (e.g., two) internal mirror surfaces mounted on a rotating support structure.

55. 发明申请

US20080208179A1 METHODS OF INCREASING SKIN PERMEABILITY BY TREATMENT WITH ELECTROMAGNETIC RADIATION 审中-公开
标题翻译：通过电磁辐射治疗增加皮肤渗透性的方法
公开(公告)号：US20080208179A1
公开(公告)日：2008-08-28
申请号：US11925693
申请日：2007-10-26
申请人： Kin F. Chan , Basil M. Hantash , Vikramaditya P. Bedi , George Frangineas
发明人： Kin F. Chan , Basil M. Hantash , Vikramaditya P. Bedi , George Frangineas
IPC分类号： A61B18/20 , A61K31/375
CPC分类号： A61B18/203 , A61B2017/00765 , A61B2018/00452 , A61B2018/0047
摘要： Methods of treating tissue with fractional laser radiation are disclosed. The fractional laser treatment methods reversibly increase skin permeability while maintaining a substantially intact stratum corneum and producing alterations within the epidermis and dermis. The alterations in the epidermis and dermis can include necrosis and/or coagulation. The alterations in the epidermis can include the creation of a plurality of pores in the stratum corneum and/or the creation of vacuoles in the layers of the epidermis below the stratum corneum. The fractional laser treatment methods disclosed herein can be used to provide treatments to the skin, to increase permeation of active substances into or through tissue, to deliver active substances locally or systemically, and to control the delivery of active substances.
摘要翻译：公开了用分数激光辐射处理组织的方法。分数激光治疗方法可逆地增加皮肤渗透性，同时保持基本上完整的角质层并在表皮和真皮中产生改变。表皮和真皮的改变可能包括坏死和/或凝血。表皮中的改变可以包括在角质层下面的表皮层中产生多个孔和/或产生空泡。本文公开的分数激光治疗方法可用于向皮肤提供治疗，以增加活性物质进入或穿过组织的渗透，以局部或全身递送活性物质，并控制活性物质的递送。

56. 发明申请

US20080161782A1 MICROPORE DELIVERY OF ACTIVE SUBSTANCES 审中-公开
标题翻译： MICROPORE交付活性物质
公开(公告)号：US20080161782A1
公开(公告)日：2008-07-03
申请号：US11925697
申请日：2007-10-26
申请人： Kin F. Chan , Basil M. Hantash , Vikramaditya P. Bedi , George Frangineas
发明人： Kin F. Chan , Basil M. Hantash , Vikramaditya P. Bedi , George Frangineas
IPC分类号： A61B18/20 , A61K31/341 , A61P17/00
CPC分类号： A61K31/375 , A61B18/203 , A61B2017/00765 , A61B2018/00452
摘要： A method and device for delivering active substances into and through the skin for treatment of the skin during and/or following fractional laser radiation treatment of the skin are described.
摘要翻译：描述了用于在皮肤的分数激光放射治疗期间和/或之后将活性物质输送到皮肤中并通过皮肤以治疗皮肤的方法和装置。

57. 发明申请

US20080088901A1 High Speed, High Efficiency Optical Pattern Generator Using Rotating Optical Elements 失效
公开(公告)号：US20080088901A1
公开(公告)日：2008-04-17
申请号：US11952925
申请日：2007-12-07
申请人： Leonard DeBenedictis , C. David Nabors , George Frangineas
发明人： Leonard DeBenedictis , C. David Nabors , George Frangineas
IPC分类号： G02B26/08
CPC分类号： G02B26/105 , G02B13/0095 , G02B26/0875 , G02B26/10 , G02B27/30 , Y10S359/90
摘要： An optical pattern generator includes one or more multi-faceted rotating optical elements that introduce an offset that is rotation insensitive. The component that generates the offset is rotationally symmetric around the rotational axis of the optical element. Thus, as the optical element rotates, the effect of the offset component does not change. In addition, rotating optical elements may be designed to counteract unwanted optical effects of each other.

58. 发明申请

US20070179481A1 Laser System for Treatment of Skin Laxity 审中-公开
标题翻译：用于治疗皮肤松弛的激光系统
公开(公告)号：US20070179481A1
公开(公告)日：2007-08-02
申请号：US11674654
申请日：2007-02-13
申请人： George Frangineas , Leonard DeBenedictis , Thomas Myers , Basil Hantash
发明人： George Frangineas , Leonard DeBenedictis , Thomas Myers , Basil Hantash
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B2018/00452 , A61B2018/0047
摘要： A method of reducing wrinkles in skin includes irradiating the skin with laser pulses to ablate an array of spaced apart voids in the skin. A region of coagulated tissue surrounds each of the voids and there viable tissue between the coagulated regions. Tissue in the coagulated regions is in tension due to shrinkage of collagen by the heat generated during the ablation. This tension rapidly closes the voids, tightening the skin and reducing the wrinkles. A healing process replaces the coagulated tissue with new tissue after a period of about one-month. The method is also applicable to lightening abnormally pigmented skin, as the new tissue replacing the coagulated tissue is not abnromally pigmented.
摘要翻译：减少皮肤皱纹的方法包括用激光脉冲照射皮肤以消除皮肤中间隔开的空隙阵列。凝结组织的区域围绕每个空隙，并且在凝结区域之间存在活组织。凝固区域中的组织由于在消融期间产生的热而使胶原收缩而处于紧张状态。这种张力会迅速关闭空隙，收紧皮肤并减少皱纹。愈合过程在大约一个月的时间内用新的组织代替凝固的组织。该方法也适用于减轻异常色素沉着的皮肤，因为替代凝固组织的新组织不会引起色素沉着。

59. 发明申请

US20070140092A1 Optical System Having Aberrations for Transforming a Gaussian Laser-Beam Intensity Profile to a Quasi-Flat-Topped Intensity Profile in a Focal Region of the Optical System 有权
标题翻译：具有用于将高斯激光束强度分布变换到光学系统的焦点区域中的准平顶强度分布的畸变的光学系统
公开(公告)号：US20070140092A1
公开(公告)日：2007-06-21
申请号：US11567614
申请日：2006-12-06
申请人： George Frangineas
发明人： George Frangineas
IPC分类号： G11B7/135 , G11B7/00
CPC分类号： G02B27/0927 , G02B27/0955
摘要： An optical system is configured for projecting an image having a quasi-flat-topped intensity profile from a laser-beam having a Gaussian intensity profile. The optical system includes a diffraction limited lens for focusing the laser beam and one or more optical elements that introduce aberration into the beam before the beam is focused. The aberration introduced causes the Gaussian intensity profile to be changed to the quasi-flat-topped intensity profile at some position in a focal region of the diffraction-limited lens.
摘要翻译：光学系统被配置为从具有高斯强度分布的激光束投影具有准平顶强度分布的图像。光学系统包括用于聚焦激光束的衍射限制透镜和在光束聚焦之前将像差引入到光束中的一个或多个光学元件。引入的像差导致高斯强度分布在衍射受限透镜的焦点区域中的某个位置处改变为准平顶强度分布。

60. 发明申请

US20060217695A1 Optically-induced treatment of internal tissue 审中-公开
标题翻译：光学诱导内部组织治疗
公开(公告)号：US20060217695A1
公开(公告)日：2006-09-28
申请号：US11354217
申请日：2006-02-13
申请人： Leonard DeBenedictis , Barry Broome , George Frangineas
发明人： Leonard DeBenedictis , Barry Broome , George Frangineas
IPC分类号： A61B18/18
CPC分类号： A61B18/201 , A61B2018/2272 , G02B5/09 , G02B26/108 , G02B26/12
摘要： An optical beam is delivered to internal target tissue, for example via two counter-rotating disks or via a single rotatable component. In one approach, two counter-rotating disks deflect an incident optical beam in a manner that generates an irradiation pattern at the target tissue. In another approach, a rotatable component includes a plurality of deflection sectors arranged around a rotation axis, and each sector deflects an incident optical beam as the sector rotates through the beam to generate an irradiation pattern at the target tissue. A probe maintains an optical channel within the human body so that the deflected optical beam can be delivered to the target tissue.
摘要翻译：光束被传送到内部目标组织，例如经由两个反向旋转盘或经由单个可旋转部件。在一种方法中，两个反向旋转盘以在目标组织处产生照射图案的方式偏转入射光束。在另一种方法中，可旋转部件包括围绕旋转轴线布置的多个偏转扇区，并且当扇区旋转穿过光束时，每个扇区使入射光束偏转，以在目标组织处产生照射图案。探针在人体内保持光通道，使得偏转的光束可以被传送到目标组织。

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