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51. 发明申请

US20120094944A1 NOVEL IMIDAZOPYRIDINE COMPOUND 失效
标题翻译：新型咪唑啉化合物
公开(公告)号：US20120094944A1
公开(公告)日：2012-04-19
申请号：US13378550
申请日：2010-06-16
申请人： Jun Takeuchi , Takayuki Inukai , Masaru Sakai
发明人： Jun Takeuchi , Takayuki Inukai , Masaru Sakai
IPC分类号： A61K31/7048 , A61K31/437 , A61K31/5377 , A61K31/496 , A61K31/541 , A61K31/55 , A61K31/56 , A61K31/606 , A61P17/00 , A61P1/00 , A61P9/04 , A61P11/00 , A61P9/00 , A61P1/16 , A61P1/04 , A61P27/14 , A61P29/00 , A61P37/06 , A61P37/08 , A61P7/10 , A61P9/06 , A61P7/00 , A61P7/02 , A61P3/10 , A61P9/12 , A61P3/04 , C07D471/04
CPC分类号： C07D471/04 , A61K31/437
摘要： For the prevention and/or treatment of chymase-mediated diseases such as skin diseases, circulatory diseases, digestive system diseases, respiratory diseases, liver diseases, ocular diseases or the like, a drug is provided having as an active ingredient a compound having extremely strong chymase inhibitory activity, high safety, and high metabolic stability. The compound represented by the formula (I): wherein all symbols have the same meanings as in the description, a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof, is useful as a pharmaceutical ingredient having chymase inhibitory activity for preventing and/or treating of chymase-mediated disease, such as skin diseases, circulatory diseases, digestive system diseases, respiratory diseases, liver diseases, ocular diseases or the like.
摘要翻译：为了预防和/或治疗胃促胰岛素介导的疾病如皮肤疾病，循环系统疾病，消化系统疾病，呼吸系统疾病，肝病，眼部疾病等，提供作为活性成分的具有极强的化合物的药物糜酶抑制活性高，安全性高，代谢稳定性高。由式（I）表示的化合物：其中所有符号具有与描述中相同的含义，其盐，其N-氧化物或其溶剂合物或其前药可用作具有糜酶抑制性的药物成分用于预防和/或治疗胃促胰腺炎介导的疾病如皮肤疾病，循环系统疾病，消化系统疾病，呼吸系统疾病，肝脏疾病，眼部疾病等的活性。

52. 发明授权

US08153319B2 System and method for purging condensate from an electrochemical cell stack prior to operation 失效
标题翻译：在操作前从电化学电池堆中清除冷凝物的系统和方法
公开(公告)号：US08153319B2
公开(公告)日：2012-04-10
申请号：US12270395
申请日：2008-11-13
申请人： Christopher J. Chuah , Jeffrey W. Schrieber , Thomas V. Doherty , Jun Takeuchi , Akifumi Otaka
发明人： Christopher J. Chuah , Jeffrey W. Schrieber , Thomas V. Doherty , Jun Takeuchi , Akifumi Otaka
IPC分类号： H01M8/04
CPC分类号： C01B3/0005 , C01B3/34 , H01M8/04223 , H01M8/04225 , H01M8/04231 , H01M8/04302 , H01M2008/1095 , Y02E60/324
摘要： A system and technique for purging condensate from an electrochemical cell stack prior to operating the stack in one of a power producing mode of operation and an electrochemical pumping mode of operation is provided. The system and technique include storing hydrogen in the anode and cathode chambers of the stack to place the stack in a shutdown state, purging the anode and cathode chambers of condensate prior to starting operation of the stack, and preventing a fuel starvation condition in the stack while purging by sequencing communication of a fuel flow and an oxidant flow to the anode chamber with an oxidant flow to the cathode chamber while purging the condensate.
摘要翻译：提供了一种用于在将功率产生操作模式和电化学泵送操作模式中的一种操作堆叠之前从电化学电池堆排出冷凝物的系统和技术。该系统和技术包括将氢气储存在堆叠的阳极和阴极室中以使堆叠处于关闭状态，在堆叠开始操作之前清除冷凝物的阳极室和阴极室，并且防止堆叠中的燃料不足状况同时通过将燃料流和氧化剂流的通信排序到氧化剂流到阴极室同时清洗冷凝物来清洗。

53. 发明授权

US08115014B2 Ethynylindole compounds 有权
标题翻译：乙炔基吲哚化合物
公开(公告)号：US08115014B2
公开(公告)日：2012-02-14
申请号：US12644378
申请日：2009-12-22
申请人： Kazuyuki Ohmoto , Satoshi Itadani , Yoshisuke Nakayama , Jun Takeuchi , Manabu Fujita
发明人： Kazuyuki Ohmoto , Satoshi Itadani , Yoshisuke Nakayama , Jun Takeuchi , Manabu Fujita
IPC分类号： C07D209/04 , A61K31/405 , A61K31/40
CPC分类号： C07D209/18
摘要： As a compound having a potent oral activity and a long-lasting cysLT1/cysLT2 receptor antagonistic activity, the compound of the formula (I): which exhibits potent antagonistic activity against the cysLT1/cysLT2 receptor, and have long-lasting effects even in case of oral administration, and therefore is useful as an oral agent for preventing and/or treating a variety of diseases, for example, respiratory disease (for example, asthma (bronchial asthma, etc.), chronic obstructive pulmonary disease (COPD), pulmonary emphysema, chronic bronchitis, pneumonia (interstitial pneumonia, etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), apnea syndrome, allergic rhinitis, sinusitis (acute sinusitis, chronic sinusitis, etc.), pulmonary fibrosis, coughing (chronic coughing, etc.), and the like) was developed.
摘要翻译：作为具有有效的口服活性和持久的cysLT1 / cysLT2受体拮抗活性的化合物，式（I）化合物：其对cysLT1 / cysLT2受体具有强的拮抗活性，并且即使在例如因此可用作预防和/或治疗各种疾病的口服药物，例如呼吸系统疾病（例如哮喘（支气管哮喘等），慢性阻塞性肺病（COPD），肺部肺气肿，慢性支气管炎，肺炎（间质性肺炎等），严重急性呼吸综合征（SARS），急性呼吸窘迫综合征（ARDS），呼吸暂停综合征，过敏性鼻炎，鼻窦炎（急性鼻窦炎，慢性鼻窦炎等），肺纤维化，咳嗽（慢性咳嗽等）等）。

54. 发明申请

US20110197091A1 SWITCH DEVICE, SWITCH CONTROL METHOD AND STORAGE SYSTEM 失效
标题翻译：开关装置，开关控制方法和存储系统
公开(公告)号：US20110197091A1
公开(公告)日：2011-08-11
申请号：US13020868
申请日：2011-02-04
申请人： Yusuke KURASAWA , Toshiaki Takeuchi , Masakazu Sakamoto , Tetsuya Kinoshita , Jun Takeuchi , Atsushi Shinohara
发明人： Yusuke KURASAWA , Toshiaki Takeuchi , Masakazu Sakamoto , Tetsuya Kinoshita , Jun Takeuchi , Atsushi Shinohara
IPC分类号： G06F11/07
CPC分类号： G06F11/0766 , G06F11/0727
摘要： A switch device includes a memory unit for storing therein an error response for each error event to be sent in response at the time of a failure with respect to a control signal that controls a storage device connected to the switch device, an error response output unit for receiving input of the control signal and sequentially outputting each error response stored in the memory unit, an operation information computing unit for detecting an operation of a calculating device, which is connected to the switch device, corresponding to each error response output by the error response output unit and for obtaining, as operation information, a condition defining the operation of the calculating device upon receiving each error response, and an operation setting unit for setting operation condition at the time of a failure based on the operation information.
摘要翻译：开关装置包括：存储单元，用于在相对于控制连接到开关装置的存储装置的控制信号的故障时响应地发送的每个错误事件存储错误响应;错误响应输出单元用于接收所述控制信号的输入并且顺序地输出存储在所述存储单元中的每个错误响应;操作信息计算单元，用于检测与所述开关装置连接的计算装置的操作，所述运算装置对应于由所述错误输出的每个错误响应响应输出单元，并且用于在接收到每个错误响应时获取定义计算装置的操作的条件作为操作信息;以及操作设置单元，用于基于操作信息设置故障时的操作条件。

55. 发明授权

US07728023B2 Indole compound and use thereof 失效
标题翻译：吲哚化合物及其用途
公开(公告)号：US07728023B2
公开(公告)日：2010-06-01
申请号：US11885018
申请日：2006-02-24
申请人： Jun Takeuchi , Yoshisuke Nakayama , Manabu Fujita
发明人： Jun Takeuchi , Yoshisuke Nakayama , Manabu Fujita
IPC分类号： A61K31/41 , A61K31/404 , C07D257/06 , C07D209/04
CPC分类号： C07D209/18 , A61K45/06 , C07D209/24 , C07D209/26 , C07D209/30 , C07D209/42 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/06 , C07D417/12
摘要： The present invention relates to a compound represented by the formula (I), wherein all symbols are as defined in the description, a salt thereof, a solvate thereof, or a prodrug thereof, which has a leukotriene receptor antagonistic activity which is expected to be more effective than those of the leukotriene receptor antagonists currently used in clinical trials. Therefore, it is useful as an agent for the prevention and/or treatment of a leukotriene-mediated disease such as a respiratory diseases such as bronchial asthma, chronic obstructive pulmonary disease, pulmonary emphysema, chronic bronchitis, pneumonia (e.g. interstitial pneumonia etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), allergic rhinitis, sinusitis (e.g. acute sinusitis, chronic sinusitis, etc.), or the like, or as an expectorant or an antiitussive.
摘要翻译：本发明涉及由式（I）表示的化合物，其中所有符号如说明书中所定义，其盐，其溶剂合物或其前药具有白三烯受体拮抗活性，预期其为比目前在临床试验中使用的白三烯受体拮抗剂更有效。因此，作为预防和/或治疗白细胞三烯介导的疾病如呼吸道疾病如支气管哮喘，慢性阻塞性肺病，肺气肿，慢性支气管炎，肺炎（例如间质性肺炎等）的药物是有用的，，严重急性呼吸综合征（SARS），急性呼吸窘迫综合征（ARDS），过敏性鼻炎，鼻窦炎（例如急性鼻窦炎，慢性鼻窦炎等）或类似物，或作为祛痰剂或镇咳药。

56. 发明授权

US07604845B2 Method for coating internal member having holes in vacuum processing apparatus and the internal member having holes coated by using the coating method 有权
标题翻译：在真空处理装置中具有孔的内部构件的涂敷方法以及使用上述涂布法涂敷的孔的内部构件
公开(公告)号：US07604845B2
公开(公告)日：2009-10-20
申请号：US10663793
申请日：2003-09-17
申请人： Jun Takeuchi , Masaaki Kishida , Tadakazu Matsunaga , Shosuke Endoh
发明人： Jun Takeuchi , Masaaki Kishida , Tadakazu Matsunaga , Shosuke Endoh
IPC分类号： B05D1/32 , C23C4/02 , C23C4/06 , C23C4/10
CPC分类号： C23C4/01 , Y10T279/23
摘要： A method of forming a coating film of ceramic material on a surface of an internal member disposed in a vacuum processing apparatus, the surface of the internal member having holes formed therein. The method involves: (A) filling the holes of the internal member with padding plugs, each of which has a core member made from a metal material and a metal-resin composite layer covering the circumferential surface of the core member, the metal-resin composite layer being a complex composed of a metal material and a resinous material exhibiting nonconjugative property to a coating film; (B) forming a ceramic coating film on the surface of the internal member by plasma spraying after step (A); and (C) extracting the padding plugs out of the holes after step (B).
摘要翻译：一种在设置在真空处理设备中的内部构件的表面上形成陶瓷材料涂膜的方法，其中内部构件的表面形成有孔。该方法包括：（A）用填充塞填充内部构件的孔，每个填充塞具有由金属材料制成的芯构件和覆盖芯构件的周面的金属树脂复合层，金属树脂复合层是由金属材料和对涂膜呈现非共轭性的树脂材料构成的络合物; （B）在步骤（A）之后通过等离子体喷涂在内部构件的表面上形成陶瓷涂膜; 和（C）在步骤（B）之后从孔中提取填充塞子。

57. 发明申请

US20090136790A1 Regulating An Oxidizer In An Electrochemical Cell Pumping System 失效
标题翻译：在电化学电池泵送系统中调节氧化剂
公开(公告)号：US20090136790A1
公开(公告)日：2009-05-28
申请号：US12270351
申请日：2008-11-13
申请人： Jeffrey W. Schrieber , Jun Takeuchi
发明人： Jeffrey W. Schrieber , Jun Takeuchi
IPC分类号： H01M8/04 , H01M2/00
CPC分类号： H01M8/04738 , C01B3/0005 , C01B3/34 , C01B2203/0205 , C01B2203/043 , C01B2203/066 , C01B2203/1241 , C01B2203/1247 , C01B2203/1604 , H01M8/04089 , H01M8/04589 , H01M8/04776 , H01M8/0491 , Y02E60/324
摘要： A technique includes operating an electrochemical cell as a pump, including providing a current to the cell and providing a fuel flow to an anode chamber of the cell. The technique includes communicating an anode exhaust flow from the anode chamber to an oxidizer and controlling the current to regulate a temperature of the oxidizer.
摘要翻译：一种技术包括将电化学电池作为泵操作，包括向电池提供电流并向电池的阳极室提供燃料流。该技术包括将阳极废气流从阳极室传递到氧化剂并控制电流以调节氧化剂的温度。

58. 发明申请

US20080188532A1 Indole Compound and Use Thereof 失效
标题翻译：吲哚化合物及其用途
公开(公告)号：US20080188532A1
公开(公告)日：2008-08-07
申请号：US11885018
申请日：2006-02-24
申请人： Jun Takeuchi , Yoshisuke Nakayama , Manabu Fujita
发明人： Jun Takeuchi , Yoshisuke Nakayama , Manabu Fujita
IPC分类号： A61K31/41 , C07D209/04 , A61K31/404 , A61P11/00 , C07D209/36 , C07D257/02
CPC分类号： C07D209/18 , A61K45/06 , C07D209/24 , C07D209/26 , C07D209/30 , C07D209/42 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/06 , C07D417/12
摘要： The present invention relates to a compound represented by the formula (I), wherein all symbols are as defined in the description, a salt thereof, a solvate thereof, or a prodrug thereof, which has a leukotriene receptor antagonistic activity which is expected to be more effective than those of the leukotriene receptor antagonists currently used in clinical trials. Therefore, it is useful as an agent for the prevention and/or treatment of a leukotriene-mediated disease such as a respiratory diseases such as bronchial asthma, chronic obstructive pulmonary disease, pulmonary emphysema, chronic bronchitis, pneumonia (e.g. interstitial pneumonia etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), allergic rhinitis, sinusitis (e.g. acute sinusitis, chronic sinusitis, etc.), or the like, or as an expectorant or an antiitussive.
摘要翻译：本发明涉及由式（I）表示的化合物，其中所有符号如说明书中所定义，其盐，其溶剂合物或其前药具有白三烯受体拮抗活性，预期其为比目前在临床试验中使用的白三烯受体拮抗剂更有效。因此，作为预防和/或治疗白细胞三烯介导的疾病如呼吸道疾病如支气管哮喘，慢性阻塞性肺病，肺气肿，慢性支气管炎，肺炎（例如间质性肺炎等）的药物是有用的，，严重急性呼吸综合征（SARS），急性呼吸窘迫综合征（ARDS），过敏性鼻炎，鼻窦炎（例如急性鼻窦炎，慢性鼻窦炎等）或类似物，或作为祛痰剂或镇咳药。

59. 再颁专利

USRE39029E1 Magnetic recording/reproducing apparatus with the recording/reproducing heads preceding the erasing heads 失效
标题翻译：具有在擦除头之前的记录/再现头的磁记录/再现装置
公开(公告)号：USRE39029E1
公开(公告)日：2006-03-21
申请号：US10349954
申请日：2003-01-24
申请人： Kouhei Baba , Haruo Ohta , Hideaki Mukae , Jun Takeuchi , Haruo Isaka
发明人： Kouhei Baba , Haruo Ohta , Hideaki Mukae , Jun Takeuchi , Haruo Isaka
IPC分类号： H04N5/93
CPC分类号： G11B5/53 , G11B5/0086 , G11B5/534 , G11B15/125 , G11B15/4675
摘要： A magnetic recording/reproducing apparatus is provided in which among diametrically oppositely disposed heads, a recording head and an erasing head of a same channel are disposed adjacently to each other. The recording head is disposed so as to precede by two tracks the erasing head with respect to a direction of cylinder rotation, when insert-editing, using a reproduced signal obtained by the recording head, erase and record timing setting and head tracking are performed and an erasing current is not applied during the reproduction by the recording head. The reproducing heads are disposed so as to be angularly apart by about 90 degrees from the recording and erasing heads, and a rotary transformer for reproduction is applied with a shield measure and then, formed as a core independently at an upper portion of the cylinder. In addition, more narrow tracks are compatibly reproduced by the recording head.
摘要翻译：提供了一种磁记录/再现装置，其中在径向相对设置的头之间，相邻通道的记录头和擦除头彼此相邻设置。记录头相对于气缸旋转方向设置在两个轨道之前，即擦除头，当使用由记录头获得的再现信号进行插入编辑时，执行擦除和记录定时设置和磁头跟踪，在记录头的再现期间不施加擦除电流。再现头被设置成与记录和擦除头成角度地分开约90度，并且用于再现的旋转变压器被施加屏蔽测量，然后在缸的上部独立地形成为芯。此外，由记录头兼容地再现更窄的轨道。

60. 发明授权

US5460919A Process of forming super high-contrast negative images and silver halide photographic material and developer being used therefor 失效
标题翻译：用于形成超高对比度负影像和卤化银照相材料和显影剂的方法
公开(公告)号：US5460919A
公开(公告)日：1995-10-24
申请号：US278823
申请日：1994-07-22
申请人： Naoki Obi , Yasuhiko Kojima , Yasuo Shigemitsu , Jun Takeuchi , Kiyoshi Suematsu
发明人： Naoki Obi , Yasuhiko Kojima , Yasuo Shigemitsu , Jun Takeuchi , Kiyoshi Suematsu
IPC分类号： G03C1/06 , G03C5/30
CPC分类号： G03C1/067 , G03C5/30
摘要： A process of forming a super high-contrast negative image is disclosed, which comprises the steps of imagewise exposing a negative-working silver halide photographic material comprising a support having thereon one or more hydrophilic colloidal layers, at least one of the one or more hydrophilic colloidal layers being a negative-working silver halide emulsion layer, and then developing the photographic material with a developer containing an aminophenol derivative developing agent and a reductone compound in the existence of an organic compound having a negative reduction potential. A negative-working silver halide photographic material and a photographic developer being used for the image-forming process are also disclosed.
摘要翻译：公开了形成超高对比度负像的方法，其包括以下步骤：将包含其上具有一个或多个亲水性胶体层的载体的负性卤化银照相材料成像曝光，所述一种或多种亲水性胶体层中的至少一种胶体层是负性卤化银乳剂层，然后在具有负还原电位的有机化合物存在下，用含有氨基苯酚衍生物显影剂和还原酮化合物的显影剂显影照相材料。还公开了用于图像形成过程的负性卤化银照相材料和照相显影剂。

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