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51. 发明授权

US07215984B2 Signal processing apparatus 失效
标题翻译：信号处理装置
公开(公告)号：US07215984B2
公开(公告)日：2007-05-08
申请号：US10838593
申请日：2004-05-04
申请人： Mohamed K. Diab , Esmaiel Kiani-Azarbayjany , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
发明人： Mohamed K. Diab , Esmaiel Kiani-Azarbayjany , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/4821 , A61B5/7203 , A61B5/7207 , A61B5/7214 , A61B5/7225 , A61B5/7239 , A61B5/7253 , A61B5/7257 , A61B5/726 , A61B6/00 , A61B8/00 , A61B8/5276 , G01N2021/3144 , G06K9/0051 , H04B1/123
摘要： The present invention involves method and apparatus for analyzing measured signals that are modeled as containing primary and secondary portions. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, the present invention involves utilizing a transformation which evaluates a plurality of possible signal coefficients in order to find appropriate coefficients. Alternatively, the present invention involves using statistical functions or Fourier transform and windowing techniques to determine the coefficients relating to two measured signals. Use of this invention is described in particular detail with respect to blood oximetry measurements.
摘要翻译：本发明涉及用于分析被建模为包含主要和次要部分的测量信号的方法和装置。系数根据根据本发明定义的模型关联两个信号。在一个实施例中，本发明涉及利用评估多个可能的信号系数以便找到适当系数的变换。或者，本发明涉及使用统计功能或傅里叶变换和加窗技术来确定与两个测量信号有关的系数。关于血液测碘法测量，特别详细地描述了本发明的用途。

52. 发明授权

US07130938B2 Method, system and program products for identifying communications adapters of a computing environment 失效
标题翻译：用于识别计算环境的通信适配器的方法，系统和程序产品
公开(公告)号：US07130938B2
公开(公告)日：2006-10-31
申请号：US10436385
申请日：2003-05-12
申请人： Frank W. Brice, Jr. , Charles W. Gainey, Jr. , Steven G. Glassen , Marten J. Halma , David W. Hollar , Jeffrey P. Kubala , Hans-Helge Lehmann , Tan Lu , Michael G. Melendy , Kenneth J. Oakes , Charles E. Shapley , Robert A. Smith , John S. Trotter , Leslie W. Wyman , Harry M. Yudenfriend
发明人： Frank W. Brice, Jr. , Charles W. Gainey, Jr. , Steven G. Glassen , Marten J. Halma , David W. Hollar , Jeffrey P. Kubala , Hans-Helge Lehmann , Tan Lu , Michael G. Melendy , Kenneth J. Oakes , Charles E. Shapley , Robert A. Smith , John S. Trotter , Leslie W. Wyman , Harry M. Yudenfriend
IPC分类号： G06F13/12 , G06F12/00 , G06F9/34
CPC分类号： G06F13/12
摘要： An input/output subsystem of a computing environment is configured as a plurality of input/output subsystem images, each of which appears to a program as an independent input/output subsystem. An input/output subsystem image includes one or more communications adapters used for communicating within the computing environment. A communications adapter is identified by hardware of the computing environment by using a first identifier, and it is identified by a program of the computing environment by using a second identifier. The identifiers can be of different sizes.
摘要翻译：计算环境的输入/输出子系统被配置为多个输入/输出子系统图像，每个子系统图像中的每一个作为独立的输入/输出子系统显示在程序中。输入/输出子系统图像包括用于在计算环境内进行通信的一个或多个通信适配器。通过使用第一标识符由计算环境的硬件标识通信适配器，并且通过使用第二标识符由计算环境的程序来标识通信适配器。标识符可以是不同的大小。

53. 发明授权

US06597933B2 Pulse oximetry sensor adapter 有权
公开(公告)号：US06597933B2
公开(公告)日：2003-07-22
申请号：US09982453
申请日：2001-10-17
申请人： Massi E. Kiani , Robert A. Smith , David R. Tobler
发明人： Massi E. Kiani , Robert A. Smith , David R. Tobler
IPC分类号： A61B500
CPC分类号： A61B5/14551 , A61B5/14552 , A61B2562/222 , G06F19/00 , Y10S439/909
摘要： An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.

54. 发明授权

US06379690B2 Keratin-based hydrogel for biomedical applications and method of production 有权
标题翻译：用于生物医学应用的角蛋白基水凝胶和生产方法
公开(公告)号：US06379690B2
公开(公告)日：2002-04-30
申请号：US09736957
申请日：2000-12-12
申请人： Cheryl R. Blanchard , Scott F. Timmons , Robert A. Smith
发明人： Cheryl R. Blanchard , Scott F. Timmons , Robert A. Smith
IPC分类号： A61F1300
CPC分类号： C08H1/06 , A61K8/042 , A61K8/65 , A61K38/1709 , A61K38/39 , A61L26/0047 , A61L26/008 , A61L27/227 , A61L27/34 , A61L27/52 , A61L27/60 , A61L31/047 , A61L31/10 , A61Q19/00 , C07K14/4741 , Y10S514/944 , Y10S530/842 , C08L89/04 , C08L89/00
摘要： A keratin hydrogel which can be used as a wound dressing and cell scaffolding. The keratin hydrogel is formed from clean, washed hair by partially oxidizing a significant percentage of disulfide linkages to form cysteic acid groups, while some disulfide linkages remain intact. The partially oxidized hair is treated with a reducing agent, thereby reducing most of the remaining disulfide linkages to cysteine-thioglycollate disulfide and cysteine groups. A soluble fraction of hair is collected and oxidized, such that the reduced sulfur groups are allowed to reform disulfide linkages, thereby binding the keratin together. The cysteic acid groups remain, providing hydrophilic sites within the hydrogel. A higher degree of partial oxidation results in a greater abundance of hydrophilic cysteic acid groups in the hydrogel.
摘要翻译：可用作伤口敷料和细胞脚手架的角蛋白水凝胶。通过部分氧化显着百分比的二硫键以形成半胱氨酸基团，由干净的洗涤毛发形成角蛋白水凝胶，而一些二硫键保持完整。用还原剂处理部分氧化的毛发，从而将大部分剩余的二硫键连接到半胱氨酸 - 巯基乙酸酯二硫化物和半胱氨酸基团。收集毛发的可溶性部分并进行氧化，使得还原的硫基团能够改性二硫键，从而将角蛋白结合在一起。残留的半胱氨酸基团，在水凝胶内提供亲水部位。较高程度的部分氧化导致水凝胶中亲水性半胱氨酸基团的丰度较大。

55. 发明授权

US06349228B1 Pulse oximetry sensor adapter 有权
标题翻译：脉搏血氧饱和度传感器适配器
公开(公告)号：US06349228B1
公开(公告)日：2002-02-19
申请号：US09404060
申请日：1999-09-23
申请人： Massi E. Kiani , Robert A. Smith , David R. Tobler
发明人： Massi E. Kiani , Robert A. Smith , David R. Tobler
IPC分类号： A61B500
CPC分类号： A61B5/14551 , A61B5/14552 , A61B2562/222 , G06F19/00 , Y10S439/909
摘要： An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.
摘要翻译：适配器允许来自一个制造商的传感器的互连与来自其他制造商的常规不兼容的监视器耦合以形成正常工作的脉搏血氧饱和度系统。适配器将监视器中的传感器驱动器与传感器的当前要求和光源配置相匹配。适配器还将传感器的光检测器信号电平与监视器前置放大器的动态范围要求相匹配。此外，适配器向监视器提供兼容的传感器校准，传感器类型和安全信息。适配器可以具有独立的电源，或者可以从监视器获得电力，从而允许被动和主动适配器组件。适配器特别适合作为适配器电缆，替代传统的患者电缆或传感器电缆作为脉搏血氧仪系统中传感器与监护仪之间的互连。

56. 发明授权

US06258356B1 Methods for controlling insect pests with compositions containing Bacillus thuringiensis strains 失效
标题翻译：用含有苏云金芽孢杆菌菌株的组合物控制害虫的方法
公开(公告)号：US06258356B1
公开(公告)日：2001-07-10
申请号：US08770452
申请日：1996-12-20
申请人： David R. Wilcox , Robert A. Smith , Terry A. Benson
发明人： David R. Wilcox , Robert A. Smith , Terry A. Benson
IPC分类号： A01N6300
CPC分类号： C07K14/325 , A01N63/00 , Y10S435/832
摘要： Novel bacterial isolates of B. thuringiensis are disclosed which have enhanced toxicity with respect to previously resistant or insufficiently susceptible insect species, including, but not limited to, Plutella xylostella, Spodoptera frugiperda and Spodoptera exigua, as well as certain secondary pests such as Trichoplusia ni. Such isolates may be characterized by their possession of a particular subset of the genes coding for the various B. thuringiensis &dgr;-endotoxin proteins and by a characteristic plasmid profile, or array, known to be associated therewith. Also disclosed are a method for the efficient identification of such bacterial isolates utilizing generalized or, alternatively, gene-specific DNA probes; cloned or synthesized nucleotide sequences which are useful in the preparation of those probes; compositions containing an insecticidally effective amount of a bacterial isolate of the invention in combination with an acceptable carrier; and a method for the use thereof in the control or eradication of insect pests.
摘要翻译：公开了苏云金芽孢杆菌的新型细菌分离物，其对先前抗性或不充分易感的昆虫物种具有增强的毒性，包括但不限于小菜蛾，草地贪夜蛾和草地夜蛾以及某些次生害虫如毛滴虫。这样的分离物的特征可以在于它们拥有编码各种苏云金芽孢杆菌δ-内毒素蛋白质的基因的特定子集，以及已知与之相关的特征性质粒谱或阵列。还公开了一种有效的方法使用广泛的或者基因特异性DNA探针鉴定这样的细菌分离物; 克隆或合成的可用于制备这些探针的核苷酸序列; 含有杀虫有效量的本发明细菌分离物与可接受载体组合的组合物; 以及用于控制或根除害虫的方法。

57. 发明授权

US06236872B1 Signal processing apparatus 失效
标题翻译：信号处理装置
公开(公告)号：US06236872B1
公开(公告)日：2001-05-22
申请号：US09199744
申请日：1998-11-25
申请人： Mohamed K. Diab , Esmaiel Kiani-Azarbayjany , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
发明人： Mohamed K. Diab , Esmaiel Kiani-Azarbayjany , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
IPC分类号： A61B500
CPC分类号： H04B1/123 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/14546 , A61B5/14551 , A61B5/4821 , A61B5/7214 , A61B5/7253 , A61B5/7257 , A61B6/00 , A61B8/00 , A61B8/5276 , G06K9/0051
摘要： The present invention involves method and apparatus for analyzing two measured signals that are modeled as containing primary and secondary portions. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, the present invention involves utilizing a transformation which evaluates a plurality of possible signal coefficients in order to find appropriate coefficients. Alternatively, the present invention involves using statistical functions or Fourier transform and windowing techniques to determine the coefficients relating to two measured signals. Use of this invention is described in particular detail with respect to blood oximetry measurements.
摘要翻译：本发明涉及用于分析被建模为包含主要和次要部分的两个测量信号的方法和装置。系数根据根据本发明定义的模型关联两个信号。在一个实施例中，本发明涉及利用评估多个可能的信号系数以便找到适当系数的变换。或者，本发明涉及使用统计功能或傅里叶变换和加窗技术来确定与两个测量信号有关的系数。关于血液测碘法测量，特别详细地描述了本发明的用途。

58. 发明授权

US6159496A Keratin-based hydrogel for biomedical applications and method of production 有权
公开(公告)号：US6159496A
公开(公告)日：2000-12-12
申请号：US365699
申请日：1999-08-02
申请人： Cheryl R. Blanchard , Scott F. Timmons , Robert A. Smith
发明人： Cheryl R. Blanchard , Scott F. Timmons , Robert A. Smith
IPC分类号： A61K38/17 , A61K38/39 , A61L26/00 , A61L27/22 , A61L27/34 , A61L27/52 , A61L27/60 , A61L31/04 , A61L31/10 , C07K14/47 , C08H1/06 , A61L15/00 , A61F13/00 , A61K9/70 , A61K38/00
CPC分类号： C08H1/06 , A61K38/1709 , A61K38/39 , A61K8/042 , A61K8/65 , A61L26/0047 , A61L26/008 , A61L27/227 , A61L27/34 , A61L27/52 , A61L27/60 , A61L31/047 , A61L31/10 , A61Q19/00 , C07K14/4741 , Y10S514/944 , Y10S530/842
摘要： A keratin hydrogel which can be used as a wound dressing and cell scaffolding. The keratin hydrogel is formed from clean, washed hair by partially oxidizing a significant percentage of disulfide linkages to form cysteic acid groups, while some disulfide linkages remain intact. The partially oxidized hair is treated with a reducing agent, thereby reducing most of the remaining disulfide linkages to cysteine-thioglycollate disulfide and cysteine groups. A soluble fraction of hair is collected and oxidized, such that the reduced sulfur groups are allowed to reform disulfide linkages, thereby binding the keratin together. The cysteic acid groups remain, providing hydrophilic sites within the hydrogel. A higher degree of partial oxidation results in a greater abundance of hydrophilic cysteic acid groups in the hydrogel.

59. 发明授权

US5890929A Shielded medical connector 失效
标题翻译：屏蔽医疗连接器
公开(公告)号：US5890929A
公开(公告)日：1999-04-06
申请号：US868164
申请日：1997-06-03
申请人： Michael A. Mills , Robert A. Smith
发明人： Michael A. Mills , Robert A. Smith
IPC分类号： H01R13/658 , H01R9/03
CPC分类号： H01R13/6599 , Y10S439/939
摘要： An electrical connector for a medical instrument has a plug containing a plurality of pins in electrical communication with wires emanating from a shielded cable that is connected to a medical sensor detecting physiological data. The plug portion of the electrical connector substantially surrounds the connection of the pins with the cable in a plastic housing. When the plug is inserted in to a socket portion of the connector mounted to a medical instrument housing, the pins electrically communicate with a plurality of tubular sockets to communicate the signals to electronic devices in a medical instrument. Surface coatings on the connector are provided to shield the wire connections with the pins and tubular sockets from electromagnetic interference (EMI). A tubular shield is also provided in the medical instrument to shield the electrical connection between the internal cable and the tubular receptacles from EMI. The EMI shields on the connector and the EMI shielding on the connecting cables are all connected to a common ground. A significant reduction in EMI distortion of the sensor signals is achieved.
摘要翻译：用于医疗器械的电连接器具有插塞，其包含多个引脚，其与从屏蔽电缆发出的电线电连通，所述屏蔽电缆连接到检测生理数据的医疗传感器。电连接器的插头部分基本上围绕塑料壳体中的销与电缆的连接。当插头插入到安装到医疗器械外壳的连接器的插座部分时，插脚与多个管状插座电连通以将信号传送到医疗器械中的电子设备。提供连接器上的表面涂层以屏蔽具有销和管状插座的电线连接免受电磁干扰（EMI）。医疗器械中还设置有管状屏蔽件，用于屏蔽内部电缆和管状插座之间的电气连接不受EMI影响。连接器上的EMI屏蔽层和连接电缆上的EMI屏蔽都连接到公共地面。实现传感器信号的EMI失真的显着降低。

60. 发明授权

US5561176A Treating process for precipitated silica fillers 失效
公开(公告)号：US5561176A
公开(公告)日：1996-10-01
申请号：US524732
申请日：1995-09-07
申请人： Theresa A. Garafalo , Robert A. Smith
发明人： Theresa A. Garafalo , Robert A. Smith
IPC分类号： C09C1/28 , C08K9/06 , C09C3/08 , C08L83/06 , C08K3/36 , C08K5/54
CPC分类号： C08K9/06 , Y10T428/2995
摘要： A process for treating fillers, preferably precipitated silica, to improve the physical property profile of heat curable and room temperature vulcanizable silicone rubbers and a composition for room temperature vulcanizable rubbers comprising the silica filler treated by the process of the invention.

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