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51. 发明申请

US20120149328A1 Devices, Systems, and Methods for Sharing Network Services 有权
标题翻译：用于共享网络服务的设备，系统和方法
公开(公告)号：US20120149328A1
公开(公告)日：2012-06-14
申请号：US12963612
申请日：2010-12-08
申请人： Soumyajit Chakraborty , James Gordon Beattie, JR. , Stephen J. Griesmer , Shiv Kumar
发明人： Soumyajit Chakraborty , James Gordon Beattie, JR. , Stephen J. Griesmer , Shiv Kumar
IPC分类号： H04M3/42 , H04W12/06
CPC分类号： H04M3/42238 , H04M2207/18 , H04W4/50 , H04W4/60 , H04W8/18 , H04W88/04
摘要： Devices, systems and methods are disclosed which relate to mobile communication device users sharing their subscribed network services with other mobile communication device users. A borrowing mobile communication device is provided with the ability to remotely connect to a lending mobile communication device and use the subscribed network services of the lending mobile communication device when needed. This method allows the user of the lending mobile communication device to share subscribed network services. Besides using network services, it is possible to share displays between two mobile communication devices. A user of a lending mobile communication device shares the current display with a borrowing mobile communication device and vice-versa. This allows sharing among people who are not family members. Any registered user may subscribe to this network service sharing service and create a peer network. Users have the option to turn sharing on or off in the lending preferences.
摘要翻译：公开了涉及与其他移动通信设备用户共享其订阅网络服务的移动通信设备用户的设备，系统和方法。提供借用的移动通信设备能够远程连接到借出的移动通信设备，并且在需要时使用借出的移动通信设备的订阅的网络服务。该方法允许借出移动通信设备的用户共享预订的网络服务。除了使用网络服务之外，还可以在两个移动通信设备之间共享显示。贷款移动通信设备的用户与借用移动通信设备共享当前显示，反之亦然。这样可以让不是家庭成员的人员共享。任何注册用户都可以订阅该网络服务共享服务并创建对等网络。用户可以选择在贷款偏好设置中打开或关闭共享。

52. 发明申请

US20120146247A1 PRE-TREATMENT OF MEMORY CARDS FOR BINDING GLUE AND OTHER CURABLE FLUIDS 审中-公开
标题翻译：预处理用于结合玻璃和其他可固化流体的记忆卡
公开(公告)号：US20120146247A1
公开(公告)日：2012-06-14
申请号：US13265666
申请日：2011-06-08
申请人： Itzhak Pomerantz , Shiv Kumar , Robert Miller , Chin-Tien Chiu , Peng Fu , Cheeman Yu , Hem Takiar , Chih Chiang Tung , Kaiyou Qian , Rahav Yairi
发明人： Itzhak Pomerantz , Shiv Kumar , Robert Miller , Chin-Tien Chiu , Peng Fu , Cheeman Yu , Hem Takiar , Chih Chiang Tung , Kaiyou Qian , Rahav Yairi
IPC分类号： H01L23/28
CPC分类号： G06K19/07732 , H01L2924/0002 , H05K5/0278 , H01L2924/00
摘要： A memory device is disclosed including at least one surface pre-treated to roughen the surface for better adhesion of a curable fluid such as glue or ink on the surface. The surface of the memory device may be pre-treated by scoring lines in the surface with a laser or by forming discrete deformations with a particle blaster. The surface may also be roughened by providing a roughened pattern on a mold plate during an encapsulation process. In further examples, the surface may be chemically pre-treated to roughen the surface and/or increase the adhesion energy of the surface.
摘要翻译：公开了一种记录装置，其包括至少一个经过预处理的表面以粗糙化表面，以便在表面上更好地粘附可固化流体例如胶水或油墨。存储器件的表面可以通过用激光在表面上刻划线或者通过用粒子喷射器形成离散的变形来预处理。在封装过程中，通过在模板上提供粗糙图案也可以使表面粗糙化。在另外的实施例中，表面可以被化学预处理以使表面粗糙化和/或增加表面的粘附能。

53. 发明申请

US20120089484A1 Methods, Devices, and Computer Program Product for Offering Media Content Based on User Preferences 审中-公开
标题翻译：基于用户偏好提供媒体内容的方法，设备和计算机程序产品
公开(公告)号：US20120089484A1
公开(公告)日：2012-04-12
申请号：US12900731
申请日：2010-10-08
申请人： Shiv Kumar , James Gordon Beattie, JR. , Soumyajit Chakraborty
发明人： Shiv Kumar , James Gordon Beattie, JR. , Soumyajit Chakraborty
IPC分类号： G06Q30/00 , G06Q40/00 , G06F15/16
CPC分类号： G06Q20/102 , G06Q30/0623
摘要： Media content is offered upon indication of receipt of a communication from a first communication device to a second communication device. A sample of media content is transmitted to the first communication device or the second communication device based on at least one preference of a user of the first communication device or the second communication device. A selection is received from the first communication device or the second communication device, indicating whether a user of the first communication device or the second communication device desires to download the media content based on the sample. If the received selection indicates that the user of the first communication device or the second communication device desires to download the media content, the media content is transmitted to the first communication device, the second communication device, or another designated device
摘要翻译：通过从第一通信设备接收到第二通信设备的通信的指示来提供媒体内容。基于第一通信设备或第二通信设备的用户的至少一个偏好，将媒体内容的示例发送到第一通信设备或第二通信设备。从第一通信设备或第二通信设备接收到选择，指示第一通信设备或第二通信设备的用户是否希望基于该样本来下载媒体内容。如果接收到的选择指示第一通信设备或第二通信设备的用户希望下载媒体内容，则将媒体内容发送到第一通信设备，第二通信设备或另一指定设备

54. 发明申请

US20110228665A1 Locally Diagnosing and Troubleshooting Service Issues 失效
标题翻译：本地诊断和故障排除服务问题
公开(公告)号：US20110228665A1
公开(公告)日：2011-09-22
申请号：US12727931
申请日：2010-03-19
申请人： Shiv Kumar , Paritosh Bajpay , Jackson Liu , Narendra Ravi , Raghvendra G. Savoor
发明人： Shiv Kumar , Paritosh Bajpay , Jackson Liu , Narendra Ravi , Raghvendra G. Savoor
IPC分类号： G06F11/00
CPC分类号： H04L12/2825 , G06Q10/06 , H04L12/2898 , H04L41/0631
摘要： A method includes detecting, at a customer premises equipment (CPE) device, a problem associated with a network device. The network device is communicatively coupled to the CPE device via a local area network. For example, the CPE device may include a residential gateway (RG). The method includes determining, at the CPE device, whether the problem associated with the network device is locally correctable. When the CPE device determines that the problem is locally correctable, the method includes initiating a corrective action to resolve the problem. When the CPE device determines that the problem is not locally correctable, the method includes sending data associated with the problem from the CPE device to a network system via a wide area network.
摘要翻译：一种方法包括在客户驻地设备（CPE）设备处检测与网络设备相关联的问题。网络设备经由局域网通信地耦合到CPE设备。例如，CPE设备可以包括住宅网关（RG）。该方法包括在CPE设备处确定与网络设备相关联的问题是否是本地可校正的。当CPE设备确定问题在本地可修正时，该方法包括启动纠正措施以解决问题。当CPE设备确定问题不能在本地可修正时，该方法包括通过广域网从CPE设备向网络系统发送与问题相关的数据。

55. 发明申请

US20090162838A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES 审中-公开
标题翻译：荧光共振能量转移酶基质
公开(公告)号：US20090162838A1
公开(公告)日：2009-06-25
申请号：US11568193
申请日：2005-04-18
申请人： Shiv Kumar , Anup Sood
发明人： Shiv Kumar , Anup Sood
IPC分类号： C12Q1/68 , C12Q1/37 , C07H21/04 , C07K14/47
CPC分类号： G01N33/542 , C12Q1/34
摘要： Disclosed are compounds of formula (I) wherein D1 is a first dye moiety whose fluorescence properties may be modulated so as to be suitable as a donor or an acceptor in an energy transfer arrangement; D2 is a second dye moiety suitable as an acceptor or a donor in an energy transfer arrangement with said first dye; L is a linking group comprises 2-200 linked atoms, wherein said linking group optionally includes an enzyme cleavage site; and M is an enzyme cleavable group chosen to modulate the fluorescence properties of D1. The compounds of formula (I) may be used as reporter molecules for detecting biochemical cleavage events in assays that employ fluorescence resonance energy transfer.
摘要翻译：公开了式（I）的化合物，其中D1是可以调节其荧光性质以适合作为能量转移装置中的给体或受体的第一染料部分; D2是第二染料部分，其适于作为与所述第一染料的能量转移装置中的受体或供体; L是包含2-200个连接原子的连接基团，其中所述连接基团任选地包括酶切割位点; M是选择调节D1荧光性质的酶切割基团。式（I）的化合物可以用作用于检测采用荧光共振能量转移的测定中生化裂解事件的报道分子。

56. 发明授权

US07256019B2 Terminal phosphate blocked nucleoside polyphosphates 有权
标题翻译：磷酸末端封闭核苷多磷酸盐
公开(公告)号：US07256019B2
公开(公告)日：2007-08-14
申请号：US10651355
申请日：2003-08-29
申请人： Anup Sood , Shiv Kumar , Carl Fuller , John Nelson
发明人： Anup Sood , Shiv Kumar , Carl Fuller , John Nelson
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/04
CPC分类号： C07H19/20 , C07H19/10 , C07H21/00 , C12Q1/6816 , C12Q1/6851 , C12Q1/6869 , C12Q2525/186
摘要： The present invention describes terminal phosphate blocked nucleoside polyphosphates that are stable at high temperature and their use in nucleic acid amplification and analysis. Current invention further describes charge modified terminal phosphate blocked nucleoside polyphosphates for improved incorporation and direct loading of nucleic acid sequencing reactions onto separating media.
摘要翻译：本发明描述了在高温下稳定的磷酸封端的磷酸核苷多磷酸，并且其用于核酸扩增和分析。本发明进一步描述了电荷修饰的末端磷酸酯封端的核苷多磷酸酯，用于改进核酸测序反应在分离介质上的掺入和直接加载。

57. 发明授权

US07244566B2 Analyte detection 有权
标题翻译：分析物检测
公开(公告)号：US07244566B2
公开(公告)日：2007-07-17
申请号：US10651582
申请日：2003-08-29
申请人： Anup Sood , Shiv Kumar , Carl Fuller , John Nelson
发明人： Anup Sood , Shiv Kumar , Carl Fuller , John Nelson
IPC分类号： C12Q1/68
CPC分类号： C12P19/34 , C12Q1/68
摘要： A method of characterizing an analyte sample is provided that includes the steps of: (a) anchoring the analyte to a nucleic acid template of known sequence; (b) conducting a DNA polymerase reaction that includes the reaction of a template, a non-hydrolyzable primer, at least one terminal phosphate-labeled nucleotide, DNA polymerase, and an enzyme having 3′→5′ exonuclease activity which reaction results in the production of labeled polyphosphate; (c) permitting the labeled polyphosphate to react with a phosphatase to produce a detectable species characteristic of the sample; (d) detecting the detectable species. The method may include the step of characterizing the nucleic acid sample based on the detection. Also provided are methods of analyzing multiple analytes in a sample, and kits for characterizing analyte samples.
摘要翻译：提供表征分析物样品的方法，其包括以下步骤：（a）将分析物锚定到已知序列的核酸模板; （b）进行DNA聚合酶反应，其包括模板，不可水解的引物，至少一个末端磷酸酯标记的核苷酸，DNA聚合酶和具有3'→5'核酸外切酶活性的酶的反应，该反应导致生产标记多磷酸盐; （c）允许标记的多磷酸酯与磷酸酶反应以产生样品的可检测物种特征; （d）检测可检测物种。该方法可以包括基于检测来表征核酸样品的步骤。还提供了分析样品中多种分析物的方法，以及用于表征分析物样品的试剂盒。

58. 发明授权

US07223541B2 Terminal-phosphate-labeled nucleotides and methods of use 有权
标题翻译：末端磷酸酯标记的核苷酸和使用方法
公开(公告)号：US07223541B2
公开(公告)日：2007-05-29
申请号：US10358818
申请日：2003-02-05
申请人： Carl Fuller , Shiv Kumar , Anup Sood , John Nelson
发明人： Carl Fuller , Shiv Kumar , Anup Sood , John Nelson
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6823 , C07H19/10 , C07H19/20 , C07H21/00 , C12Q1/6816 , C12Q1/6851 , C12Q2521/525
摘要： The present invention relates to improved methods of detecting a target using a labeled substrate or substrate analog. The methods comprise reacting the substrate or substrate analog in an enzyme-catalyzed reaction which produces a labeled moiety with independently detectable signal only when such substrate or substrate analog reacts. The present invention, in particular, describes methods of detecting a nucleic acid in a sample, based on the use of terminal-phosphate-labeled nucleotides as substrates for nucleic acid polymerases. The methods provided by this invention utilize a nucleoside polyphosphate, dideoxynucleoside polyphosphate, or deoxynucleoside polyphosphate analogue which has a colorimetric dye, chemiluminescent, or fluorescent moiety, a mass tag or an electrochemical tag attached to the terminal-phosphate. When a nucleic acid polymerase uses this analogue as a substrate, an enzyme-activatable label would be present on the inorganic polyphosphate by-product of phosphoryl transfer. Cleavage of the polyphosphate product of phosphoryl transfer via phosphatase leads to a detectable change in the label attached thereon. When the polymerase assay is performed in the presence of a phosphatase, there is provided a convenient method for real-time monitoring of DNA or RNA synthesis and detection of a target nucleic acid.
摘要翻译：本发明涉及使用标记的底物或底物类似物检测靶的改进方法。所述方法包括在酶催化的反应中使底物或底物类似物反应，其仅在这种底物或底物类似物反应时产生具有独立可检测信号的标记部分。本发明特别地描述了基于使用末端磷酸酯标记的核苷酸作为核酸聚合酶的底物来检测样品中核酸的方法。本发明提供的方法利用了具有比色染料，化学发光或荧光部分的核苷多磷酸，双脱氧核苷多聚磷酸酯或脱氧核苷多聚磷酸酯类似物，连接至末端磷酸酯的质量标签或电化学标签。当核酸聚合酶使用该类似物作为底物时，酶活性标记将存在于磷酸转移的无机多磷酸盐副产物上。通过磷酸酶切割磷酸转移的多磷酸盐产物导致附着在其上的标签的可检测的变化。当在磷酸酶的存在下进行聚合酶测定时，提供了用于实时监测DNA或RNA合成和检测靶核酸的方便的方法。

59. 发明授权

US06967250B1 Energy transfer dyes 失效
标题翻译：能量转移染料
公开(公告)号：US06967250B1
公开(公告)日：2005-11-22
申请号：US09386576
申请日：1999-08-30
申请人： Shiv Kumar , Satyam Nampalli , Mahesh Khot
发明人： Shiv Kumar , Satyam Nampalli , Mahesh Khot
IPC分类号： C07D265/36 , G01N33/542
CPC分类号： G01N33/542
摘要： Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from them offer a wide variety of fluorescent labels with large Stokes' shifts enabling their use in a variety of fluorescence applications over a wide range of the visible spectrum.
摘要翻译：公开了能量转移染料，它们的制备及其作为生物系统中的标记物的用途。染料优选为使其能够附着于各种生物材料的盒的形式。可以由其制成的染料和试剂提供了广泛的荧光标记，具有大的斯托克斯变化，使其能够在广泛的可见光谱范围内用于各种荧光应用。

60. 发明授权

US06906185B1 Derivatives of 7-deaza -2′-deoxyguanosine-5'-triphosphate, preparation and use thereof 失效
标题翻译： 7-脱氮-2'-脱氧鸟苷-5'-三磷酸的衍生物，的制备和用途
公开(公告)号：US06906185B1
公开(公告)日：2005-06-14
申请号：US09045732
申请日：1998-03-20
申请人： Carl W. Fuller , Mark McDougall , Shiv Kumar
发明人： Carl W. Fuller , Mark McDougall , Shiv Kumar
IPC分类号： C07H19/173 , C07H21/04 , C12P19/32
CPC分类号： C07H19/173 , C07H21/04
摘要： Derivatives of 7-deaza-2′-deoxyguanosine are described. Also described is the use of such compounds in synthesis of nucleic acid polymers and in methods for determining a nucleotide base sequence.
摘要翻译：描述了7-脱氮-2'-脱氧鸟苷的衍生物。还描述了这样的化合物在核酸聚合物的合成中的用途以及用于测定核苷酸碱基序列的方法。

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