会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 54. 发明授权
    • Peptides, process for preparation thereof and use thereof
    • 肽,其制备方法和用途
    • US4354966A
    • 1982-10-19
    • US193453
    • 1980-10-03
    • Yoshihiko KitauraOsamu NakaguchiKeiji HemmiMatsuhiko ArataniHidekazu TakenoSatoshi OkadaHirokazu TanakaMasashi Hashimoto
    • Yoshihiko KitauraOsamu NakaguchiKeiji HemmiMatsuhiko ArataniHidekazu TakenoSatoshi OkadaHirokazu TanakaMasashi Hashimoto
    • A61K38/00C07K5/02C07K9/00C07C103/52
    • C07C243/00C07K5/0215C07K9/005C12R1/465A61K38/00
    • The invention relates to novel peptides and their pharmaceutically acceptable salts, particularly useful for pharmaceutical purposes such as in the therapeutic treatment of infectious diseases caused by pathogenic microorganisms. The compounds have the structure ##STR1## wherein R.sup.1 is hydrogen or acyl;R.sup.2 is carboxy or protected carboxy or a group of the formula: --COHN--R.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl;R.sup.3 is carboxy, protected carboxy, lower alkyl, hydroxyphenyl, carbamoyl or a group of the formula: ##STR2## wherein R.sub.a.sup.3 is hydrogen, amino, protected amino or acylamino, R.sub.b.sup.3 is carboxy or protected carboxy;R.sup.p is carboxy, protected carboxy, carbamoyl, carboxy (lower) alkyl or protected carboxy (lower) alkyl;l is an integer 2,m is an integer 0 to 2 andn is an integer 1,provided that,whenR.sup.1 is hydrogen or acyl,R.sup.2 is carboxy, protected carboxy or a group of the formula: --CONHR.sub.a.sup.2 wherein R.sub.a.sup.2 is carboxy (lower) alkyl or protected carboxy (lower) alkyl,R.sup.p is carboxy, or protected carboxy, m is an integer 2, thenR.sup.3 is carbamoyl, lower alkyl or hydroxyphenyl or a group of the formula: ##STR3## wherein R.sub.a.sup.3 is hydrogen or acylamino and R.sub.b.sup.3 is carboxy or protected caboxy, andwhenR.sup.p is carbamoyl, thenR.sup.1 is acyl.
    • 本发明涉及新型肽及其药学上可接受的盐,特别可用于药物目的,例如由病原微生物引起的感染性疾病的治疗性治疗。 这些化合物具有结构,其中R 1是氢或酰基; R2是羧基或保护的羧基或下式基团-COHN-Ra2,其中Ra2是羧基(低级)烷基或被保护的羧基(低级)烷基; R 3是羧基,保护的羧基,低级烷基,羟基苯基,氨基甲酰基或下式的基团:其中R 3a是氢,氨基,被保护的氨基或酰氨基,R 3b是羧基或被保护的羧基; Rp是羧基,保护的羧基,氨基甲酰基,羧基(低级)烷基或被保护的羧基(低级)烷基; l为整数2,m为整数0〜2,n为整数1,条件是当R 1为氢或酰基时,R 2为羧基,被保护的羧基或式-CONHRa 2基团,其中Ra 2为羧基( 低级)烷基或受保护的羧基(低级)烷基,Rp是羧基或受保护的羧基,m是整数2,则R3是氨基甲酰基,低级烷基或羟基苯基或下式的基团:其中R 3a是氢或酰基氨基 并且R 3b是羧基或被保护的环氧基,当Rp是氨基甲酰基时,则R1是酰基。
    • 56. 发明授权
    • Grease pump unit
    • 油脂泵单元
    • US09315372B2
    • 2016-04-19
    • US14009704
    • 2012-01-17
    • Hiroyuki DoiHirokazu Tanaka
    • Hiroyuki DoiHirokazu Tanaka
    • B67D7/36B67D7/04F16N7/38F16N11/10F16N25/00
    • B67D7/04F16N7/385F16N11/10F16N25/00Y10T137/2931
    • A grease pump unit has a metering valve 37 and a grease supplying device 50 in which a suction tube 16 on a pump device 11 extends through a follower plate 19 in a grease can 100, grease in the grease can 100 being sucked through the suction tube 16 and discharged through a discharge port 17 by activation of the pump device 11. Provided are a bubble dividing device 32 which supplies the grease discharged through the discharge port 17 through an supply pipe 24 to micronize bubbles in the grease and which supplies the grease through a supply pipe 36 to the metering valve 37, and a return pipe 47 which returns a portion of the grease not discharged through the metering valve 37 into the grease can 100 via the follower plate 19.
    • 油脂泵单元具有计量阀37和润滑脂供给装置50,其中泵装置11上的吸入管16通过润滑脂罐100中的从动板19延伸,润滑脂罐100中的润滑脂通过吸管 并且通过泵装置11的激活通过排出口17排出。气泡分离装置32通过供给管24供给通过排出口17排出的油脂,以微粉化润滑脂中的气泡,并且通过 向计量阀37供给的供给管36,以及通过从动板19使未经计量阀37排出的润滑脂的一部分返回到润滑脂罐100中的回流管47。
    • 57. 发明授权
    • Lid member with waterproof function, and method of manufacturing thereof
    • 具有防水功能的盖构件及其制造方法
    • US09014767B2
    • 2015-04-21
    • US13814096
    • 2011-10-27
    • Hirokazu TanakaOsamu ItoYuichi Kakihara
    • Hirokazu TanakaOsamu ItoYuichi Kakihara
    • H04M1/00H04M1/02H01R13/52B23P19/00
    • H04M1/0202B23P19/00H01R13/5213H01R2201/16Y10T29/49826
    • A lid member with a waterproof function opening and closing an opening portion formed in a housing is structured by a rubber-like elastic material seal portion provided with a projection portion which is integrally formed in one surface of a resin main body of the lid member and is stored within the opening portion, an annular projection portion which is integrally formed in an outer peripheral surface of the projection portion and comes into close contact with a peripheral surface of the opening portion, and a reinforcing portion which extends from the annular projection portion to the vicinity of a junction portion of the outer peripheral surface with the main body, and a thermoplastic elastomer retention portion which exists so as to come into close contact with an outer peripheral surface of the reinforcing portion, and is integrally formed in a side of the main body.
    • 具有打开和关闭形成在壳体中的开口部分的防水功能的盖构件由橡胶状弹性材料密封部分构成,该橡胶状弹性材料密封部分设置有一体地形成在盖构件的树脂主体的一个表面中的突出部分, 存储在开口部内的环状突起部,其一体形成在突出部的外周面并与开口部的周面紧密接触;以及加强部,其从环状突起部延伸到 外周面与主体的接合部附近,以及与加强部的外周面紧密接触的热塑性弹性体保持部,并且一体地形成在 主体。