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51. 发明授权

US07264596B2 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US07264596B2
公开(公告)日：2007-09-04
申请号：US10010213
申请日：2001-12-04
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B10/00 , A61B17/32
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

52. 发明授权

US07229418B2 Tissue specimen encapsulation device and method thereof 有权
标题翻译：组织标本包封装置及其方法
公开(公告)号：US07229418B2
公开(公告)日：2007-06-12
申请号：US10342867
申请日：2003-01-14
申请人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
发明人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
IPC分类号： A61B10/00 , A61B18/18 , A61B17/32
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00234 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2017/00287 , A61B2017/2212 , A61B2017/320064 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. The guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. In another aspect of the device, the guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates.
摘要翻译：用于封装组织样本的装置包括棒组件，护套和引导组件。引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。棒组件靠近组织标本设置，通常是相邻的或通过样本。引导组件具有围绕组织标本设置的护套展开部件。当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。在装置的另一方面，导向组件是围绕组织标本旋转的臂或壳体。当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。

53. 发明授权

US06540693B2 Methods and apparatus for securing medical instruments to desired locations in a patients body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US06540693B2
公开(公告)日：2003-04-01
申请号：US09146185
申请日：1998-09-01
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B1000
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

54. 发明授权

US07488295B2 Tissue acquisition system and method of use 有权
公开(公告)号：US07488295B2
公开(公告)日：2009-02-10
申请号：US09981525
申请日：2001-10-16
申请人： Fred Burbank , Paul Lubock , Michael L. Jones
发明人： Fred Burbank , Paul Lubock , Michael L. Jones
IPC分类号： A61B10/00 , A61B17/32
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2010/0225 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A tissue acquisition system includes radio frequency (RF) cutter loops which are extendable out a cannula to cut cylindrical tissue samples from a tissue of interest in a patient. The cannula includes inner and outer cannulae which are mutually rotatable and include cutouts through which the cutting loop can be rotated and longitudinally extended to perform the cuts. The tissue samples are then aspirated proximally through the cannula for collection.

55. 发明授权

US07651467B2 Dilation devices and methods for removing tissue specimens 有权
标题翻译：用于去除组织标本的扩张装置和方法
公开(公告)号：US07651467B2
公开(公告)日：2010-01-26
申请号：US10933182
申请日：2004-09-02
申请人： Paul Lubock , Richard L. Quick
发明人： Paul Lubock , Richard L. Quick
IPC分类号： A61B10/00 , A61M29/00 , A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： The invention provides devices and methods for use in removing tissue samples from within a patient's body. The devices include instruments having shafts for cutting a path to a tissue mass, and an inflatable balloon or balloons attached to the shaft effective to dilate the path upon inflation in order to aid in the removal of tissue masses from within the body of a patient. The devices also include instruments having dilation plates that may be inserted into a path leading to a tissue mass to be removed, and the plates separated effective to dilate the path to aid in the removal of tissue masses. Methods include inserting a device into a path leading to a tissue mass, and inflating a balloon or separating plates, thereby widening the path, and removing the tissue mass. Such devices and methods find use, for example, in biopsy and in lumpectomy procedures.
摘要翻译：本发明提供了用于从患者体内去除组织样本的装置和方法。装置包括具有用于切割到组织块的路径的杆的仪器，以及附接到轴的可充气气球或气囊，其有效地在充气时扩张路径，以帮助从患者体内移除组织块。这些装置还包括具有扩张板的仪器，其可以插入到通向待移除的组织块的路径中，并且板分离有效以扩张路径以帮助去除组织块。方法包括将装置插入通向组织块的路径中，并且使球囊或分离板膨胀，从而使路径变宽，并去除组织块。这样的装置和方法可用于例如活组织检查和乳房切除手术。

56. 发明授权

US07449022B2 Shapeable electrosurgical scalpel 有权
标题翻译：可锻电刀手术刀
公开(公告)号：US07449022B2
公开(公告)日：2008-11-11
申请号：US10446507
申请日：2003-05-27
申请人： Richard L. Quick , Martin Shabaz , Dan Kussman , Paul Lubock
发明人： Richard L. Quick , Martin Shabaz , Dan Kussman , Paul Lubock
IPC分类号： A61B18/18
CPC分类号： A61B17/32002 , A61B10/0266 , A61B18/14 , A61B18/1402 , A61B2018/00208 , A61B2018/00601 , A61B2018/1405 , A61B2018/1407 , A61B2018/1861
摘要： The invention is directed to an electrosurgical device having a shapeable elongate cutting electrode having a free distal end with an exposed length of at least 0.5 inch and secured by its proximal end to the distal end of a handle. The electrosurgical device is designed for use with a high frequency electrosurgical generator which has an output at a frequency of between about 1 MHz and about 10 MHz, preferably about 3 to about 8 MHz. Preferably, the output has an essentially sinusoidal waveform with little harmonic distortion. The methods provide for the enhanced cutting of a variety of tissue including muscular, connective, glandular and fatty tissue. The device is particularly suitable in performing a breast biopsy.
摘要翻译：本发明涉及一种具有可成形的细长切割电极的电外科装置，其具有自由远端，其暴露长度至少为0.5英寸，并通过其近端固定到手柄的远端。电外科设备设计用于高频电外科发生器，其具有在约1MHz至约10MHz之间，优选约3至约8MHz的频率的输出。优选地，输出具有几乎没有谐波失真的基本正弦波形。该方法提供了增强切割各种组织，包括肌肉，结缔，腺体和脂肪组织。该装置特别适用于进行乳腺活检。

57. 发明申请

US20080125766A1 MRI imageable assembly 审中-公开
公开(公告)号：US20080125766A1
公开(公告)日：2008-05-29
申请号：US11980302
申请日：2007-10-30
申请人： Paul Lubock , Richard L. Quick , Ethan Broadaway
发明人： Paul Lubock , Richard L. Quick , Ethan Broadaway
IPC分类号： A61B18/18
CPC分类号： A61B17/3468 , A61B5/055 , A61B17/3498 , A61B90/39 , A61B2017/00477 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： A marker delivery device is described which has an obturator with an elongated shaft, an inner lumen, a proximal end, and a substantially sealed distal end. One or more tissue markers are deployed within the inner lumen of the elongated shaft of the obturator. Preferably, the tissue marker(s) is disposed within an inner lumen of a marker delivery tube which is disposed within the inner lumen of the elongated shaft of the obturator. The marker delivery tube has an opening for discharging the tissue markers into a body (e.g. biopsy) cavity. The distal tip of the marker delivery tube is configured to penetrate the substantially sealed distal end of the obturator so that tissue markers can be delivered while the obturator is in place within the body. Preferably, the obturator includes a detectable element capable of producing a relatively significant image signature during MRI.

58. 发明授权

US06607528B1 Shapeable electrosurgical scalpel 有权
标题翻译：可锻电刀手术刀
公开(公告)号：US06607528B1
公开(公告)日：2003-08-19
申请号：US09752265
申请日：2000-12-29
申请人： Richard L. Quick , Martin Shabaz , Dan Kussman , Paul Lubock
发明人： Richard L. Quick , Martin Shabaz , Dan Kussman , Paul Lubock
IPC分类号： A61B1818
CPC分类号： A61B17/32002 , A61B10/0266 , A61B18/14 , A61B18/1402 , A61B2018/00208 , A61B2018/00601 , A61B2018/1405 , A61B2018/1407 , A61B2018/1861
摘要： The invention is directed to an electrosurgical device having a shapeable elongate cutting electrode having a free distal end with an exposed length of at least about 0.25 inch and secured by its proximal end to the distal end of a handle. The electrosurgical device is designed for use with a high frequency electrosurgical generator which has an output at a frequence of between about 1 MHz and about 10 MHz, preferably about 3 to about 8 MHz. Preferably, the output has an essentially sinusoidal waveform with little harmonic distortion. The methods provide for the enhanced cutting of a variety of tissue including muscular, connective, glandular and fatty tissue. The device is particularly suitable in performing a breast biopsy.
摘要翻译：本发明涉及一种具有可成形的细长切割电极的电外科装置，其具有自由远端，暴露长度至少约0.25英寸，并通过其近端固定到手柄的远端。电外科设备设计用于高频电外科发生器，其具有频率在约1MHz至约10MHz之间，优选约3至约8MHz的输出。优选地，输出具有几乎没有谐波失真的基本正弦波形。该方法提供了增强切割各种组织，包括肌肉，结缔，腺体和脂肪组织。该装置特别适用于进行乳腺活检。

59. 发明授权

US09095325B2 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US09095325B2
公开(公告)日：2015-08-04
申请号：US11438955
申请日：2006-05-22
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B10/00 , A61B10/02 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

60. 发明授权

US08641640B2 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US08641640B2
公开(公告)日：2014-02-04
申请号：US11981292
申请日：2007-10-31
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

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