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51. 发明授权

US07838844B2 Radiopharmaceutical system and method utilizing radio-frequency identification tags 有权
标题翻译：使用射频识别标签的放射性药物系统和方法
公开(公告)号：US07838844B2
公开(公告)日：2010-11-23
申请号：US12067186
申请日：2006-09-21
申请人： Gary S. Wagner , Chad M. Gibson , Frank M. Fago
发明人： Gary S. Wagner , Chad M. Gibson , Frank M. Fago
IPC分类号： B01D59/44
CPC分类号： G21G4/08 , G06K7/10178 , G21F5/018
摘要： The invention, in one characterization, may be said to be directed to a radiopharmaceutical system. In some embodiments, the system may include a radioisotope elution component and a radio-frequency identification (RFID) tag coupled to the radioisotope elution component. Other embodiments may include a radiation shielded enclosure having an interior, an exterior, and a radio-frequency identification (RFID) communication transmission passage extending between the interior and the exterior.
摘要翻译：在一个表征中，本发明可以说是针对放射性药物系统。在一些实施方案中，系统可以包括放射性同位素洗脱组分和耦合到放射性同位素洗脱组分的射频识别（RFID）标签。其他实施例可以包括具有内部，外部和在内部和外部之间延伸的射频识别（RFID）通信传输通道的辐射屏蔽外壳。

52. 发明授权

US07692173B2 Radiopharmaceutical pig 失效
标题翻译：放射性药物猪
公开(公告)号：US07692173B2
公开(公告)日：2010-04-06
申请号：US11956835
申请日：2007-12-14
申请人： Frank M. Fago , David W. Wilson , Matt Bantly
发明人： Frank M. Fago , David W. Wilson , Matt Bantly
IPC分类号： G21F5/00 , G21F5/18 , A61B19/10
CPC分类号： A61M5/1785 , A61J1/16 , A61M5/007 , G21F5/015 , G21F5/018 , Y10T29/4998 , Y10T29/49982
摘要： A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.
摘要翻译：使用制药猪将含有液体放射性药物的注射器从放射性药物运送到医疗设施以给予患者。制药猪包括细长聚合物盖，其可拆卸地连接到细长聚合物基底。细长聚合物盖包括完全包围帽屏蔽元件的帽壳，细长聚合物基底包括完全包围基底屏蔽元件的基底壳。用于盖壳和基壳的聚合物优选为聚碳酸酯树脂，例如LEXAN。不利用内衬，并且盖屏蔽元件和基本屏蔽元件（其优选但不必须由铅构成）被完全密封和未曝光。

53. 发明申请

US20100063390A1 UNIVERSAL SYRINGE 审中-公开
标题翻译：通用SYRINGE
公开(公告)号：US20100063390A1
公开(公告)日：2010-03-11
申请号：US12595566
申请日：2008-04-08
申请人： Frank M. Fago , Charles Neer
发明人： Frank M. Fago , Charles Neer
IPC分类号： A61B6/00 , A61M5/178
CPC分类号： A61M5/14546 , A61M5/007 , A61M5/14566 , A61M2005/14553
摘要： Syringes for use with medical fluid injectors. In certain aspects, the syringe includes a body having a longitudinal axis, a forward end, and a rearward end. At least one syringe mating section is coupled to the body of the syringe and is adapted to operatively engage an injector. In some embodiments, the syringe mating section includes first, second, and third flanges extending outwardly from the body along a plane substantially perpendicular to the longitudinal axis. In some embodiments, the syringe mating section includes a first flange having a cross-section of a parallelogram and a second flange having a tapered surface. In some embodiments, the syringe mating section includes a flange having an L-shaped cross-section. Other embodiments of the syringe mating section may include yet other appropriate designs.
摘要翻译：用于医用液体注射器的注射器。在某些方面，注射器包括具有纵向轴线，前端和后端的主体。至少一个注射器配合部分联接到注射器的主体并且适于可操作地接合注射器。在一些实施例中，注射器配合部分包括沿着基本上垂直于纵向轴线的平面从身体向外延伸的第一，第二和第三凸缘。在一些实施例中，注射器配合部分包括具有平行四边形横截面的第一凸缘和具有锥形表面的第二凸缘。在一些实施例中，注射器配合部分包括具有L形横截面的凸缘。注射器配合部分的其它实施例可以包括其他合适的设计。

54. 发明授权

US07495246B2 Radiopharmaceutical pig 失效
标题翻译：放射性药物猪
公开(公告)号：US07495246B2
公开(公告)日：2009-02-24
申请号：US11486197
申请日：2006-07-13
申请人： Frank M. Fago , Matt Bantly , David W. Wilson
发明人： Frank M. Fago , Matt Bantly , David W. Wilson
IPC分类号： G21F5/18 , B65D83/10 , A61N5/00
CPC分类号： A61M5/1785 , A61J1/16 , A61M5/007 , G21F5/015 , G21F5/018 , Y10T29/4998 , Y10T29/49982
摘要： A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.
摘要翻译：使用制药猪将含有液体放射性药物的注射器从放射性药物运送到医疗设施以给予患者。制药猪包括细长聚合物盖，其可拆卸地连接到细长聚合物基底。细长聚合物盖包括完全包围帽屏蔽元件的帽壳，细长聚合物基底包括完全包围基底屏蔽元件的基底壳。用于盖壳和基壳的聚合物优选为聚碳酸酯树脂，例如LEXAN。不利用内衬，并且盖屏蔽元件和基本屏蔽元件（其优选但不必须由铅构成）被完全密封和未曝光。

55. 发明申请

US20080245977A1 Radiopharmaceutical Dispenser Having Counter-Forced Access Mechanism and System and Method Therewith 审中-公开
标题翻译：具有反强制访问机制的放射性药物分配器及其系统和方法
公开(公告)号：US20080245977A1
公开(公告)日：2008-10-09
申请号：US11995737
申请日：2006-07-26
申请人： Frank M. Fago , Gary S. Wagner
发明人： Frank M. Fago , Gary S. Wagner
IPC分类号： H01J5/18 , G21F5/00
CPC分类号： G21F5/018 , A61J1/16 , A61J1/201 , A61J1/2096 , A61M5/1782 , A61M5/1785
摘要： The present invention generally relates to systems and methods for accessing a radiation shielded enclosure at least partially made of a radiation shielding material. For example, some systems of the invention include a radiation shielded receptacle configured to receive a radiopharmaceutical and a cover that is removably disposable across an opening into the receptacle. A counter-force mechanism may be biasingly coupled to the receptacle or the cover or a combination thereof. This counter-force mechanism may be said to exhibit a range of positions including a closed position, in which the cover is disposed across the opening, and an open position, in which the opening is uncovered.
摘要翻译：本发明一般涉及用于访问至少部分由辐射屏蔽材料制成的辐射屏蔽外壳的系统和方法。例如，本发明的一些系统包括被配置为接纳放射性药物的辐射屏蔽插座和可移除地一次性穿过插入插座的开口的盖。反力机构可以偏置地联接到接收器或盖或其组合。这种反力机构可以被认为表现出一定范围的位置，其包括封闭位置，其中盖布置在开口处，以及打开位置，其中开口未被覆盖。

56. 发明申请

US20080215007A1 Disposable Front Loadable Syringe and Injector 有权
标题翻译：一次性前装式注射器和注射器
公开(公告)号：US20080215007A1
公开(公告)日：2008-09-04
申请号：US12107988
申请日：2008-04-23
申请人： Frank M. Fago , Frank M. Lewis
发明人： Frank M. Fago , Frank M. Lewis
IPC分类号： A61M37/00 , A61M5/31
CPC分类号： A61M5/14546 , A61M5/14566 , A61M5/344 , A61M5/346 , A61M2005/14553 , A61M2005/3103
摘要： A syringe for an injector that has at its nozzle end a connection to the fluid delivery tubing that prevents, reduces, or eliminates fluid leaks, by virtue of a ridge on the external surfaces of the connector which engage to tubing. Furthermore, the syringe and injector are configured to permit the syringe to be oriented in more than one manner on the injector.
摘要翻译：用于注射器的注射器，其在其喷嘴端具有与流体输送管的连接，其通过与管道接合的连接器的外表面上的脊部来防止，减少或消除流体泄漏。此外，注射器和注射器构造成允许注射器在注射器上以多于一种方式定向。

57. 发明申请

US20080200747A1 Radiopharmaceutical Pigs and Portable Powered Injectors 审中-公开
标题翻译：放射性药物猪和便携式动力注射器
公开(公告)号：US20080200747A1
公开(公告)日：2008-08-21
申请号：US11914263
申请日：2006-05-16
申请人： Gary S. Wagner , Frank M. Fago , Keith M. Grispo , Chad M. Gibson , John H. Lewis , William E. Bausmith , Elaine E. Haynes , David W. Wilson , Vernon D. Ortenzi , Elaine Borgemenke
发明人： Gary S. Wagner , Frank M. Fago , Keith M. Grispo , Chad M. Gibson , John H. Lewis , William E. Bausmith , Elaine E. Haynes , David W. Wilson , Vernon D. Ortenzi , Elaine Borgemenke
IPC分类号： A61N5/00 , G21F5/018 , G01N23/10
CPC分类号： A61M5/14546 , A61M5/007 , A61M5/1456 , A61M5/16827 , A61M5/172 , A61M5/1785 , A61M2005/14506 , A61M2205/60 , A61M2205/6018
摘要： One aspect of the present invention is directed to a system for power filling a syringe with a radiopharmaceutical from a vial while attempting to provide low exposure to radiation, and thereafter, power injecting the radiopharmaceutical. A radiation-shielded container of the system generally holds the vial. A filling and injecting device of the system generally includes a mounting structure adapted to support the syringe with a needle of the syringe located in the vial. An electromechanical drive of the system may be commanded by a control to pull a syringe plunger through a controlled motion, thereby filling the syringe.
摘要翻译：本发明的一个方面涉及一种用于在试图提供低辐射照射的情况下从小瓶中用放射性药物填充注射器的系统，然后对放射性药物进行动力注射。系统的辐射屏蔽容器通常保持小瓶。系统的灌注和注射装置通常包括适于将注射器的针头置于小瓶中的针筒上的安装结构。系统的机电驱动可由控制器命令以通过受控运动拉动注射器柱塞，由此填充注射器。

58. 发明申请

US20080188808A1 Heat Retention Devices for Syringes and Uses Thereof 审中-公开
标题翻译：注射器及其用途的保温装置
公开(公告)号：US20080188808A1
公开(公告)日：2008-08-07
申请号：US11914409
申请日：2006-05-31
申请人： Michael R. Hynes , Frank M. Fago
发明人： Michael R. Hynes , Frank M. Fago
IPC分类号： A61M5/44 , A61M5/31
CPC分类号： A61M5/445 , A61M5/007 , A61M2205/3633
摘要： The present invention relates to heat-retaining syringe jackets for reducing the cooling rate of medical fluids held inside syringes and methods of using such syringe jackets. An exemplary syringe jacket of the invention may include a material that experiences a phase transition at a phase transition temperature. Additionally or alternatively, the exemplary syringe jacket may include a material exhibiting a high specific heat.
摘要翻译：本发明涉及用于降低保持在注射器内的医用流体的冷却速度的保温注射器护套和使用这种注射器护套的方法。本发明的示例性注射器套管可以包括在相变温度下经历相变的材料。另外或替代地，示例性注射器套管可以包括表现出高比热的材料。

59. 发明授权

US06780170B2 Hydraulic remote for a medical fluid injector 有权
标题翻译：液压遥控器用于医用液体注射器
公开(公告)号：US06780170B2
公开(公告)日：2004-08-24
申请号：US10146696
申请日：2002-05-15
申请人： Frank M. Fago , James E. Knipfer , Charles S. Neer
发明人： Frank M. Fago , James E. Knipfer , Charles S. Neer
IPC分类号： A61M3700
CPC分类号： A61M31/005 , A61M5/14546 , A61M5/14566 , A61M5/168 , A61M2005/14264 , A61M2005/14553 , A61M2205/215 , A61M2205/582
摘要： A hand-held remote for a medical fluid injector includes a syringe and a conduit which may be coupled to a pressure transducer on a control circuit of the injector. Movement of a plunger within a syringe body on the syringe creates a pressure which is sensed by the pressure transducer and the control circuit responds to the sensed pressure by causing fluid to be ejected from, or drawn into, a syringe mounted to the injector. The pressure developed by the remote provides tactile feedback to an operator for improved control over injections.
摘要翻译：用于医疗流体注射器的手持遥控器包括注射器和可以连接到注射器的控制电路上的压力传感器的导管。柱塞在注射器体内在注射器上的运动产生了由压力传感器感测到的压力，并且控制电路通过使流体从安装到喷射器上的注射器喷射或吸入流体来响应感测到的压力。由遥控器开发的压力为操作者提供触觉反馈，以改善对注射的控制。

60. 发明授权

US06511459B1 Syringe plunger having an improved sealing ability 有权
标题翻译：注射柱塞具有改善的密封能力
公开(公告)号：US06511459B1
公开(公告)日：2003-01-28
申请号：US09676143
申请日：2000-09-29
申请人： Frank M. Fago
发明人： Frank M. Fago
IPC分类号： A61M5178
CPC分类号： A61M5/31511 , A61M5/31513 , A61M2005/31516
摘要： A plunger is provided for a syringe that includes a pressure relief mechanism that exhausts any fluid trapped in the chamber between sealing flanges carried by the plunger when the plunger is advanced to dispense fluid from the syringe. The contact pressure between the barrel-contacting surface of the rearmost sealing flange nearest the access opening of the syringe barrel is weakened relative to the contact pressure provided by the barrel-contacting surface of the sealing flange that isolates the fluid within the barrel. The contact pressure of the rearmost sealing flange may be lessened by either reducing its radial diameter relative to the radial diameter of the other sealing flange, removing an underlying portion of the plunger, or configuring the rearmost sealing flange as deflectable sealing lip.
摘要翻译：提供了一种用于注射器的柱塞，其包括压力释放机构，该压力释放机构在柱塞前进以从注射器分配流体时排出被柱塞承载的密封凸缘之间被捕获在腔室中的任何流体。最靠近注射器筒的进入开口的最后密封凸缘的与枪管接触的表面之间的接触压力相对于密封法兰的筒接触表面提供的接触压力而减弱，所述接触压力将管内的流体隔离。通过相对于另一个密封凸缘的径向直径减小其径向直径，去除柱塞的下面部分或将最后面的密封凸缘配置为可偏转的密封唇，可以减小最后面的密封凸缘的接触压力。

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