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51. 发明授权

US09750629B2 Implantable restriction system tension release mechanism 有权
公开(公告)号：US09750629B2
公开(公告)日：2017-09-05
申请号：US12562267
申请日：2009-09-18
申请人： Daniel F. Dlugos, Jr. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
发明人： Daniel F. Dlugos, Jr. , Randal T. Byrum , Toralf Bork , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Richard W. Timm , Eric W. Thompson , Lauren S. Weaner
IPC分类号： A61B17/122 , A61F5/00 , A61F2/00
CPC分类号： A61F5/0053 , A61F2/0036 , A61F5/003 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.

52. 发明授权

US09402626B2 Rotary actuatable surgical fastener and cutter 有权
标题翻译：旋转式可手动紧固件和切割器
公开(公告)号：US09402626B2
公开(公告)日：2016-08-02
申请号：US13552232
申请日：2012-07-18
申请人： Mark S. Ortiz , Frederick E. Shelton, IV
发明人： Mark S. Ortiz , Frederick E. Shelton, IV
IPC分类号： A61B17/068 , A61B1/005 , A61B19/00 , A61B17/00 , A61B17/29 , A61B17/32
CPC分类号： A61B17/068 , A61B1/0052 , A61B1/0057 , A61B17/32002 , A61B90/37 , A61B2017/003 , A61B2017/0042 , A61B2017/2905 , A61B2017/291 , A61B2017/2919 , A61B2017/2927 , A61B2017/2947 , A61B2034/306 , A61B2090/372
摘要： Methods and devices are provided for controlling movement of a working end of a surgical device. In one embodiment, methods and devices are provided for moving an end effector on a distal end of a surgical fastening device. Movement can include rotational movement of the end effector about an axis of the shaft, articulation of the end effector relative to the shaft, and actuation of an end effector, e.g., closing, firing, and/or cutting. In other embodiments, a single cable actuator is provided and is movable between a first position, in which it is effective to rotate an end effector without actuating (i.e., closing and firing) the end effector, and a second position, in which it is effective to actuate the end effector without rotating the end effector. In other aspects, methods and devices are provided for moving a flexible neck formed on a distal end of an accessory channel for use with an endoscope. Movement of the flexible neck can be used to control positioning of a tool extending through the flexible neck.
摘要翻译：提供了用于控制手术装置的工作端的移动的方法和装置。在一个实施例中，提供了用于移动外科紧固装置的远端上的端部执行器的方法和装置。运动可以包括端部执行器围绕轴的轴线的旋转运动，端部执行器相对于轴的铰接，以及端部执行器的致动，例如闭合，点火和/或切割。在其它实施例中，提供单个电缆致动器并且可在第一位置之间移动，在第一位置中，有效地旋转端部执行器而不致动（即，闭合和点火）末端执行器，以及第二位置，有效地致动末端执行器而不旋转端部执行器。在其他方面，提供了用于移动形成在附件通道的远端上的柔性颈部以用于内窥镜的方法和装置。柔性颈部的运动可用于控制延伸穿过柔性颈部的工具的定位。

53. 发明授权

US09314247B2 Tissue stapler having a thickness compensator incorporating a hydrophilic agent 有权
标题翻译：具有并入亲水剂的厚度补偿器的组织吻合器
公开(公告)号：US09314247B2
公开(公告)日：2016-04-19
申请号：US13532820
申请日：2012-06-26
申请人： Frederick E. Shelton, IV , Rao S. Bezwada , Mark S. Ortiz
发明人： Frederick E. Shelton, IV , Rao S. Bezwada , Mark S. Ortiz
IPC分类号： A61B17/068 , A61B17/10 , A61B17/072 , A61B17/064 , A61B17/115 , A61B17/00 , A61B17/29 , A61B17/32 , A61B19/00
CPC分类号： A61B17/0643 , A61B17/00491 , A61B17/0644 , A61B17/068 , A61B17/0682 , A61B17/072 , A61B17/07207 , A61B17/07292 , A61B17/105 , A61B17/1155 , A61B17/2909 , A61B2017/00004 , A61B2017/00314 , A61B2017/00327 , A61B2017/00526 , A61B2017/0053 , A61B2017/00561 , A61B2017/00818 , A61B2017/00862 , A61B2017/00884 , A61B2017/00889 , A61B2017/00893 , A61B2017/00898 , A61B2017/00938 , A61B2017/00942 , A61B2017/0641 , A61B2017/07228 , A61B2017/07235 , A61B2017/07242 , A61B2017/07264 , A61B2017/07271 , A61B2017/07278 , A61B2017/07285 , A61B2017/2908 , A61B2017/2919 , A61B2017/2923 , A61B2017/2927 , A61B2017/2933 , A61B2017/2936 , A61B2017/2937 , A61B2017/320052 , A61B2090/0807
摘要： A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a the staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different the staples. The compressible tissue thickness compensator comprising a lyophilized foam having a hydrophillic agent embedded therein.
摘要翻译：用于外科缝合器的钉仓组件。该组件具有一个带有主体的盒体，该主体具有多个具有开口的缝合腔的支撑部分。还有多个钉，其中每个钉的至少一部分可移除地存储在钉腔内。每个订书钉可以在未燃位置和点火位置之间移动，并且可在未烧制配置和烧制配置之间变形。组件还包括构造成捕获在钉内的可压缩组织厚度补偿器。可压缩组织厚度补偿器至少部分地覆盖钉腔开口。压缩的组织厚度补偿器构造成在不同的钉内具有不同的压缩高度。可压缩组织厚度补偿器包括具有嵌入其中的亲水剂的冻干泡沫。

54. 发明申请

US20150119849A1 METHODS AND DEVICES FOR ACTIVATING BROWN ADIPOSE TISSUE WITH COOLING 审中-公开
标题翻译：用于用冷却活化棕色脂肪组织的方法和装置
公开(公告)号：US20150119849A1
公开(公告)日：2015-04-30
申请号：US13977555
申请日：2011-12-21
申请人： Taylor W. Aronhalt , Lee M. Kaplan , Nicholas Stylopoulos , Jason L. Harris , Dwight D. Henninger , James W. Voegele , Mark S. Ortiz
发明人： Taylor W. Aronhalt , Lee M. Kaplan , Nicholas Stylopoulos , Jason L. Harris , Dwight D. Henninger , James W. Voegele , Mark S. Ortiz
IPC分类号： A61F7/10 , A61M5/142
CPC分类号： A61F7/10 , A61F7/106 , A61F2007/0035 , A61F2007/0036 , A61F2007/0044 , A61F2007/0047 , A61F2007/029 , A61F2007/108
摘要： Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure.
摘要翻译：提供了用于通过冷却来激活棕色脂肪组织（BAT）的方法和装置。通常，方法和装置可以激活BAT以增加产热，例如增加患者的热产生，其随着时间推移可导致体重减轻和/或改善的代谢功能。在一个实施例中，提供了通过冷却具有高密度冷敏感热感器的组织和/或直接冷却BAT储存器来激活BAT的医疗装置，从而增加BAT中的产热，并通过能量引起体重减轻和/或改善的代谢功能支出。

55. 发明授权

US08876844B2 Anastomosis reinforcement using biosurgical adhesive and device 有权
标题翻译：使用生物手术粘合剂和装置进行吻合加固
公开(公告)号：US08876844B2
公开(公告)日：2014-11-04
申请号：US11555392
申请日：2006-11-01
申请人： Mark S. Ortiz , Fredrick E. Shelton, IV
发明人： Mark S. Ortiz , Fredrick E. Shelton, IV
IPC分类号： A61B17/08 , A61B17/11 , A61B17/3205 , A61B17/29 , A61B17/10
CPC分类号： A61B17/1114 , A61B17/083 , A61B17/10 , A61B17/29 , A61B17/32053 , A61B2017/1139
摘要： An exemplary anastomosis device comprises a proximal ring, a distal ring, and a middle ring. The middle ring has apertures configured to communicate a fluid such as an adhesive. The exemplary anastomosis device also has arms joining the proximal ring to the center member and arms joining the distal ring to the center member. The anastomosis device is configured to move from an unactuated position, where it has a generally cylindraceous configuration, to an actuated position, where it has a generally rivet-like configuration. The anastomosis device may be used to provide and secure an anastomosis between adjacent tissue walls. Adhesive may be communicated through the apertures of the middle ring of the anastomosis device to seal or strengthen the anastomosis. An applier may be used to deploy the anastomosis device and to communicate the adhesive through the apertures.
摘要翻译：示例性吻合装置包括近端环，远端环和中间环。中间环具有构造成连通例如粘合剂的流体的孔。示例性吻合装置还具有将近端环连接到中心构件的臂和将远端环连接到中心构件的臂。吻合装置被构造成从具有大致圆柱形构造的未致动位置移动到致动位置，其中其具有大致铆钉状构造。吻合装置可用于提供并确保相邻组织壁之间的吻合。粘合剂可以通过吻合装置的中间环的孔连通以密封或加强吻合。可以使用施放器来部署吻合装置并且通过孔传送粘合剂。

56. 发明授权

US08875972B2 End effector coupling arrangements for a surgical cutting and stapling instrument 有权
标题翻译：用于外科切割和缝合器械的末端执行器联接装置
公开(公告)号：US08875972B2
公开(公告)日：2014-11-04
申请号：US13027641
申请日：2011-02-15
申请人： William B. Weisenburgh, II , Jerome R. Morgan , Kyle P. Moore , Mark H. Ransick , Steven G. Hall , Randall J. Tanguay , Jeffrey D. Messerly , Galen C. Robertson , Andrew M. Zwolinski , Jeffrey S. Swayze , Thomas W. Huitema , Glen A. Armstrong , Shailendra K. Parihar , Donna L. Korvick , Richard W. Timm , Kevin R. Doll , Bret W. Smith , William D. Kelly , Ronald J. Kolata , Joshua R. Uth , Charles J. Scheib , Geoffrey C. Hueil , Mark S. Ortiz , Douglas B. Hoffman , Patrick A. Weizman , Dean B. Bruewer , Gregory B. Blair , Frederick E. Shelton, IV
发明人： William B. Weisenburgh, II , Jerome R. Morgan , Kyle P. Moore , Mark H. Ransick , Steven G. Hall , Randall J. Tanguay , Jeffrey D. Messerly , Galen C. Robertson , Andrew M. Zwolinski , Jeffrey S. Swayze , Thomas W. Huitema , Glen A. Armstrong , Shailendra K. Parihar , Donna L. Korvick , Richard W. Timm , Kevin R. Doll , Bret W. Smith , William D. Kelly , Ronald J. Kolata , Joshua R. Uth , Charles J. Scheib , Geoffrey C. Hueil , Mark S. Ortiz , Douglas B. Hoffman , Patrick A. Weizman , Dean B. Bruewer , Gregory B. Blair , Frederick E. Shelton, IV
IPC分类号： A61B17/068 , A61B17/072 , A61B17/29 , A61B17/00
CPC分类号： A61B17/105 , A61B17/068 , A61B17/07207 , A61B17/3205 , A61B17/3209 , A61B2017/00473 , A61B2017/07214 , A61B2017/2931
摘要： In various embodiments, a surgical stapling instrument can include a handle, a shaft extending from the handle, wherein the shaft defines an axis, and a disposable loading unit which is assembled to the shaft in a direction which is transverse to the shaft axis. Such a connection between the disposable loading unit and the shaft can prevent, or at least inhibit, the disposable loading unit from being unintentionally displaced proximally and/or distally relative to the shaft of the surgical instrument. The surgical stapling instrument and/or disposable loading unit can further include a threaded collar and/or detent assembly configured to hold the disposable loading unit in place. In various embodiments, a disposable loading unit can include a lockout feature which can prevent, or at least inhibit, an expended disposable loading unit from being reassembled to the elongated body of the surgical instrument.
摘要翻译：在各种实施例中，外科缝合器械可以包括手柄，从手柄延伸的轴，其中轴限定轴线，以及一个一次性加载单元，其在横向于轴线的方向上组装到轴上。一次性加载单元和轴之间的这种连接可以防止或至少阻止一次性加载单元相对于外科器械的轴向近侧和/或远端被无意地移位。外科缝合器械和/或一次性装载单元还可包括构造成将一次性装载单元保持在适当位置的螺纹环和/或制动组件。在各种实施例中，一次性加载单元可以包括锁定特征，其可以防止或至少抑制消耗的一次性装载单元被重新组装到外科器械的细长主体。

57. 发明授权

US08715294B2 Gastric instrument sleeve to prevent cross contamination of stomach content and provide fixation and repeatable path 有权
标题翻译：胃仪器套管，以防止胃内容物的交叉污染，并提供固定和可重复的路径
公开(公告)号：US08715294B2
公开(公告)日：2014-05-06
申请号：US11197783
申请日：2005-08-05
申请人： Mark S. Ortiz , William J. Kraimer , David B. Griffith , Lynetta J. Freeman
发明人： Mark S. Ortiz , William J. Kraimer , David B. Griffith , Lynetta J. Freeman
IPC分类号： A61F11/00
CPC分类号： A61B1/2736 , A61B17/3417 , A61B17/3421 , A61B17/3474 , A61B17/3478 , A61B17/3498 , A61B2017/00243 , A61B2017/00278 , A61B2017/00867 , A61B2017/3425 , A61B2017/3445 , A61B2017/3484 , A61B2017/3486 , A61B2017/3488
摘要： A transgastric instrument provides a sterile and repeatable pathway to and through a gastric wall for the purpose of facilitating endoscopic transgastric procedures. The instrument includes at least one guide tube having a proximal end and a distal end, the distal end being shaped and dimensioned for positioning adjacent a desired location along the gastric wall. The instrument also includes a fixation mechanism at the distal end of the guide tube for selectively securing the distal end of the guide tube at a desired location along the gastric wall. An otomy creation device circumferentially smaller than the guide tube extends through the guide tube, the otomy creation device including a distal end shaped and dimensioned for cutting and dilating the gastric wall.
摘要翻译：经胃仪器为胃壁提供无菌且可重复的途径，以便于内镜经胃手术。所述器械包括至少一个具有近端和远端的导管，所述远端的形状和尺寸用于沿着胃壁邻近所需位置定位。仪器还包括在引导管的远端处的固定机构，用于将引导管的远端选择性地固定在沿着胃壁的期望位置。造型装置周向地小于引导管延伸穿过引导管，所述造口装置包括形状和尺寸用于切割和扩张胃壁的远端。

58. 发明授权

US08591532B2 Automatically adjusting band system 有权
标题翻译：自动调整乐队系统
公开(公告)号：US08591532B2
公开(公告)日：2013-11-26
申请号：US12029806
申请日：2008-02-12
申请人： Mark S. Ortiz , Daniel F. Dlugos, Jr. , David N. Plescia , David C. Yates , Jason L. Harris , Mark S. Zeiner
发明人： Mark S. Ortiz , Daniel F. Dlugos, Jr. , David N. Plescia , David C. Yates , Jason L. Harris , Mark S. Zeiner
IPC分类号： A61B17/08
CPC分类号： A61F5/005 , F04B43/09 , F04B43/12
摘要： Devices and methods for forming a restriction in a patient are disclosed. In one exemplary embodiment, a restriction system is provided including an implantable restriction device, an implantable port in fluid communication with the implantable restriction device, and an implantable pump in fluid communication with the restriction device. In general, the implantable restriction device is adjustable and configured to form a restriction in a patient, and the implantable port is configured to receive fluid from a fluid source external to the patient. The implantable pump has a plurality of actuators configured to change shape upon the application of energy thereto such that sequential activation of the plurality of actuators is effective to create pumping action to move fluid through the pump.
摘要翻译：公开了在患者体内形成限制的装置和方法。在一个示例性实施例中，提供了限制系统，其包括可植入式限制装置，与可植入限制装置流体连通的可植入端口以及与限制装置流体连通的可植入泵。通常，可植入式限制装置是可调节的并且构造成在患者体内形成限制，并且可植入端口构造成从患者外部的流体源接收流体。可植入泵具有多个致动器，其构造成在施加能量时改变形状，使得多个致动器的顺序启动有效地产生泵送动作以使流体移动通过泵。

59. 发明授权

US08585628B2 Methods and devices for regulating the activation of ghrelin hormones within a stomach 有权
标题翻译：调节胃内生长素释放激素激活的方法和装置
公开(公告)号：US08585628B2
公开(公告)日：2013-11-19
申请号：US13105006
申请日：2011-05-11
申请人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
发明人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
IPC分类号： A61B19/00
CPC分类号： A61F5/0076 , A61B2017/0404 , A61F5/0083
摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.
摘要翻译：方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

60. 发明授权

US08500756B2 Quick load mechanism for a surgical suturing apparatus 有权
标题翻译：手术缝合装置的快速装载机构
公开(公告)号：US08500756B2
公开(公告)日：2013-08-06
申请号：US11394169
申请日：2006-03-31
申请人： Christopher A. Papa , Michael J. Stokes , Frederick E. Shelton, IV , Mark S. Ortiz
发明人： Christopher A. Papa , Michael J. Stokes , Frederick E. Shelton, IV , Mark S. Ortiz
IPC分类号： A61B17/04
CPC分类号： A61B1/005 , A61B1/00087 , A61B1/00094 , A61B1/00133 , A61B1/0014 , A61B1/2736 , A61B1/313 , A61B5/026 , A61B5/0261 , A61B17/00491 , A61B17/0466 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0493 , A61B17/06066 , A61B17/062 , A61B34/20 , A61B90/36 , A61B2017/00022 , A61B2017/00292 , A61B2017/00296 , A61B2017/00407 , A61B2017/00469 , A61B2017/00477 , A61B2017/00561 , A61B2017/0479 , A61B2017/0496 , A61B2017/06076 , A61B2017/0608 , A61B2017/06185 , A61B2017/306 , A61B2090/037 , A61B2090/0811 , A61B2090/374 , A61B2090/378
摘要： A surgical suturing apparatus includes a flexible member having a proximal end and a distal end. The proximal end has a handle attached thereto and the distal end has a suturing body attached thereto. The handle is operatively connected to the suturing body. The suturing body includes a suture housing in which a needle and drive assembly are housed for movement of the needle with a suture secured thereto about an arcuate path facilitating application of a suture to tissue. A mechanism is provided for accommodating and operating different sized needles and different sized sutures while maintaining the operative connection between the handle and the suturing body.
摘要翻译：手术缝合装置包括具有近端和远端的柔性构件。近端具有附接到其上的手柄，并且远端具有附接到其上的缝合体。手柄可操作地连接到缝合体。缝合体包括缝线壳体，其中容纳针和驱动组件，用于使针的移动，其中缝合线固定到其周围的弓形路径，从而有助于将缝合线施加到组织。提供了用于容纳和操作不同尺寸的针和不同尺寸的缝合线的机构，同时保持手柄和缝合体之间的操作连接。

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