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51. 发明授权

US07184829B2 Method and system for nerve stimulation prior to and during a medical procedure 有权
标题翻译：在医疗过程之前和期间神经刺激的方法和系统
公开(公告)号：US07184829B2
公开(公告)日：2007-02-27
申请号：US10768999
申请日：2004-01-30
申请人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
发明人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
IPC分类号： A61N1/362
CPC分类号： A61N1/36114 , A61N1/056 , A61N1/362 , A61N1/36514 , A61N1/37288 , A61N1/385 , A61N1/39
摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. Systems and devices for performing the medical procedure are also provided.
摘要翻译：提供了一种执行诸如手术的医疗程序的方法。刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。医疗程序在心脏或另一个器官上进行。停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。心脏本身也可能被刺激到跳动状态，例如通过起搏。可以继续刺激神经以允许继续医疗程序。还提供用于执行医疗程序的系统和设备。

52. 发明授权

US07184828B2 Method and system for spinal cord stimulation prior to and during a medical procedure 有权
标题翻译：在医疗过程之前和期间脊髓刺激的方法和系统
公开(公告)号：US07184828B2
公开(公告)日：2007-02-27
申请号：US10716810
申请日：2003-11-19
申请人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
发明人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
IPC分类号： A61N1/36
CPC分类号： A61N1/36014 , A61N1/36021 , A61N1/3625 , A61N1/385
摘要： A method of performing a medical procedure, such as surgery, is provided. The spinal cord is stimulated in order to control at least one physiological function. The medical procedure is performed and stimulation of the spinal cord is stopped.
摘要翻译：提供了一种执行诸如手术的医疗程序的方法。刺激脊髓以控制至少一种生理功能。执行医疗程序并停止对脊髓的刺激。

53. 发明授权

US07066882B2 System, method and apparatus for regulating vacuum supplied to surgical tools 失效
标题翻译：用于调节提供给外科手术工具的真空的系统，方法和装置
公开(公告)号：US07066882B2
公开(公告)日：2006-06-27
申请号：US10925387
申请日：2004-08-25
申请人： Scott E. Jahns , Glen Holmberg
发明人： Scott E. Jahns , Glen Holmberg
IPC分类号： A61B1/32
CPC分类号： G05D16/2013 , A61B2017/00017 , A61B2017/00243 , A61B2017/0243 , A61B2017/306 , G05D16/10 , Y10S137/907 , Y10T137/7759 , Y10T137/7761
摘要： A system, method and apparatus for regulating vacuum applied to surgical suction devices allowing the use of a single vacuum regulator and associated canister to provide vacuum to two suction devices, such as a suction stabilizer and a suction retractor. Vacuum controllers may be placed in the vacuum lines provided to each of two or more suction devices, or may be placed only in the vacuum line of the suction device believed most likely to detach during the procedure. Each vacuum controller is provided with a primary vacuum line, coupling its associated suction device to the output of the vacuum regulator and a pilot passage, also coupling the suction device to the vacuum regulator. The controller closes a valve in the main vacuum line in response to loss of vacuum attachment, which valve remains closed until attachment is reestablished. Closure of the valve results in substantial or complete blockage of the main vacuum line. The pilot passage, which may be part of the valve or a separate vacuum line, serves to allow reestablishment of vacuum attachment while the valve is closed. The pilot passage is configured so that airflow through the pilot passage is low enough that the other suction device or devices coupled to the vacuum regulator can still maintain vacuum attachment.
摘要翻译：一种用于调节施加到手术抽吸装置上的真空的系统，方法和装置，允许使用单个真空调节器和相关联的罐向两个抽吸装置（例如抽吸稳定器和抽吸牵开器）提供真空。真空控制器可以放置在设置到两个或更多个抽吸装置中的每一个的真空管线中，或者可以仅放置在被认为最可能在该过程期间分离的抽吸装置的真空管线中。每个真空控制器设置有一个初级真空管线，将其相关联的抽吸装置连接到真空调节器的输出端，以及一个先导通道，也将抽吸装置连接到真空调节器。控制器响应于真空附件的损失而关闭主真空管线中的阀门，该阀门保持关闭，直到附件被重新建立。阀的关闭导致主真空管线的实质或完全堵塞。可以是阀门或单独的真空管线的一部分的先导通道用于允许在阀门关闭时重新建立真空附件。引导通道被配置成使得通过导向通道的气流足够低，使得联接到真空调节器的另一个抽吸装置仍能保持真空附着。

54. 发明授权

US06718208B2 Method and system for nerve stimulation prior to and during a medical procedure 有权
标题翻译：在医疗过程之前和期间神经刺激的方法和系统
公开(公告)号：US06718208B2
公开(公告)日：2004-04-06
申请号：US10207725
申请日：2002-07-29
申请人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
发明人： Michael R. S. Hill , Scott E. Jahns , James R. Keogh
IPC分类号： A61N136
CPC分类号： A61N1/36114 , A61N1/056 , A61N1/362 , A61N1/36514 , A61N1/37288 , A61N1/385 , A61N1/39
摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. Systems and devices for performing the medical procedure are also provided.
摘要翻译：提供了一种执行诸如手术的医疗程序的方法。刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。医疗程序在心脏或另一个器官上进行。停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。心脏本身也可能被刺激到跳动状态，例如通过起搏。可以继续刺激神经以允许继续医疗程序。还提供用于执行医疗程序的系统和设备。

55. 发明授权

US10278723B2 Vessel sealing devices 有权
公开(公告)号：US10278723B2
公开(公告)日：2019-05-07
申请号：US12688219
申请日：2010-01-15
申请人： Scott E. Jahns , James R. Keogh , Paul A. Pignato , Christopher P. Olig , Karen P. Montpetit , Cynthia T. Clague , Raymond W. Usher , Philip J. Haarstad , Gary W. Guenst
发明人： Scott E. Jahns , James R. Keogh , Paul A. Pignato , Christopher P. Olig , Karen P. Montpetit , Cynthia T. Clague , Raymond W. Usher , Philip J. Haarstad , Gary W. Guenst
IPC分类号： A61B17/04 , A61B17/11 , A61B17/3205
摘要： A device for temporarily sealing an opening in a blood vessel is provided. The device comprises a cutting mechanism for creating an opening in a blood vessel and a seal for sealing the opening in the blood vessel. The seal is delivered through an inner lumen of a tool body coupled to the cutting mechanism. Methods for using the device to construct an anastomosis between two vessels are also provided.

56. 发明授权

US08454634B2 Vessel sealing devices 有权
标题翻译：船舶密封装置
公开(公告)号：US08454634B2
公开(公告)日：2013-06-04
申请号：US11604956
申请日：2006-11-28
申请人： Scott E. Jahns , James R. Keogh , Paul A. Pignato , Christopher P. Olig , Karen P. Montpetit , Cynthia T. Clague , Raymond W. Usher , Philip J. Haarstad , Gary W. Guenst
发明人： Scott E. Jahns , James R. Keogh , Paul A. Pignato , Christopher P. Olig , Karen P. Montpetit , Cynthia T. Clague , Raymond W. Usher , Philip J. Haarstad , Gary W. Guenst
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/32053 , A61B17/0482 , A61B17/11 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： A device for temporarily sealing an opening in a blood vessel is provided. The device comprises a cutting mechanism for creating an opening in a blood vessel and a seal for sealing the opening in the blood vessel. The seal is delivered through an inner lumen of a tool body coupled to the cutting mechanism. Methods for using the device to construct an anastomosis between two vessels are also provided.
摘要翻译：提供了用于临时密封血管中的开口的装置。该装置包括用于在血管中形成开口的切割机构和用于密封血管中的开口的密封件。密封件通过联接到切割机构的工具主体的内腔传送。还提供了使用该装置来构建两个血管之间的吻合的方法。

57. 发明授权

US08377082B2 Methods and apparatus for making precise incisions in body vessels 有权
标题翻译：在体内精确切口的方法和装置
公开(公告)号：US08377082B2
公开(公告)日：2013-02-19
申请号：US10694037
申请日：2003-10-27
申请人： Cynthia T. Clague , Scott E. Jahns , Paul T. Rothstein , Thomas P. Daigle , Raymond W. Usher
发明人： Cynthia T. Clague , Scott E. Jahns , Paul T. Rothstein , Thomas P. Daigle , Raymond W. Usher
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/32053 , A61B17/12 , A61B17/320016 , A61B2017/00243 , A61B2017/0243 , A61B2017/1107 , A61B2017/306 , A61B2017/320064
摘要： Methods and apparatus employed in surgery involving making precise incisions through body vessel walls, particularly coronary arteries. A body vessel cutting instrument comprises an elongated instrument shaft extending between a shaft proximal end adapted to be manipulated outside the patient's body and a shaft distal end and having a shaft axis and first and second cutting blades supported at the shaft distal end. The first cutting blade extends substantially orthogonally or laterally to the shaft axis and has a first cutting edge extending along a trailing side, a cutting tip at the first cutting blade free end, and an atraumatic blunt surface along the leading side. The second cutting blade has a second cutting edge extending along a leading side, whereby the first and second cutting edges face one another and are brought together to slit a vessel wall.
摘要翻译：在手术中使用的方法和装置包括通过体血管壁，特别是冠状动脉进行精确切口。身体血管切割仪器包括细长的仪器轴，其在适于被操纵在患者身体外部的轴近端和轴远端之间延伸并且具有轴轴线，以及支撑在所述轴远端处的第一和第二切割刀片。第一切割刀片基本上垂直或横向地延伸到轴线，并且具有沿着后侧延伸的第一切割边缘，在第一切割刀片自由端处的切割尖端以及沿着前侧的无损伤钝角表面。第二切割刀片具有沿着前侧延伸的第二切削刃，由此第一切削刃和第二切削刃彼此面对并且一起切开血管壁。

58. 发明授权

US08273072B2 Devices and methods for interstitial injection of biologic agents into tissue 有权
标题翻译：将生物制剂间插注入组织的装置和方法
公开(公告)号：US08273072B2
公开(公告)日：2012-09-25
申请号：US12621037
申请日：2009-11-18
申请人： Scott E. Jahns , Gary S. Oehme , Matthew D. Bonner , James R. Keogh
发明人： Scott E. Jahns , Gary S. Oehme , Matthew D. Bonner , James R. Keogh
IPC分类号： A61M31/00
CPC分类号： A61B17/3478 , A61B17/00234 , A61B17/205 , A61B2017/00247 , A61B2017/00876 , A61B2017/2936 , A61B2017/2943 , A61B2017/306 , A61B2018/00392 , A61B2090/034 , A61M5/32 , A61M2025/0086 , A61M2025/0087
摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for transversely driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force transverse to the shaft. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.
摘要翻译：将生物制剂注入组织的装置和方法。设备具有细长的轴和远端注射头，用于将针横向驱动到组织中，并通过针将药剂注射到组织中。沿着轴引导的纵向力可以平移到与轴垂直的针驱动力。一些装置提供可控的可变针穿透深度。设备包括利用四个连杆缩放仪，齿条和小齿轮的机械针驱动器和用于将第一滚针轴承体朝向第二组织接触体驱动的驱动轭。其他装置包括用于驱动和缩回针的可充气构件。还有其它装置包括用于在延伸和/或缩回位置偏置针的磁体。本发明包括用心外膜将心脏细胞前体细胞注入梗死心肌组织的微创方法。

59. 发明授权

US07976543B2 Electrosurgical methods and apparatus for making precise incisions in body vessels 有权
标题翻译：电动手术方法和装置，用于精确切开体内血管
公开(公告)号：US07976543B2
公开(公告)日：2011-07-12
申请号：US11698332
申请日：2007-01-26
申请人： Cynthia T. Clague , Philip J. Haarstad , Scott E. Jahns , James R. Keogh , Christopher P. Olig , Raymond W. Usher
发明人： Cynthia T. Clague , Philip J. Haarstad , Scott E. Jahns , James R. Keogh , Christopher P. Olig , Raymond W. Usher
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/14 , A61B18/1482 , A61B2018/00386 , A61B2018/1407 , A61B2090/034 , A61B2090/036
摘要： Methods and apparatus employed in surgery involving making precise incisions in vessels of the body, particularly cardiac blood vessels in coronary revascularization procedures conducted on the stopped or beating heart are disclosed. Such incisions are created by applying an elongated electrosurgical cutting electrode to the outer surface of the vessel wall in substantially parallel alignment with the body vessel axis, the elongated electrosurgical cutting electrode having a predetermined cutting electrode length exceeding the cutting electrode width. RF energy is applied between the electrosurgical cutting electrode and the ground electrode at an energy level and for a duration sufficient to cut an elongated slit through the vessel wall where the elongated electrosurgical cutting electrode is applied to the surface of the vessel wall.
摘要翻译：公开了涉及在停止或跳动的心脏进行的冠状动脉血运重建手术中精确切开身体血管，特别是心脏血管的手术方法和装置。这种切口是通过将细长的电外科切割电极以与体血管轴线基本平行对准的方式将细长的电外科切割电极施加到血管壁的外表面而形成的，细长的电外切割电极具有超过切割电极宽度的预定切割电极长度。 RF能量在电外科切割电极和接地电极之间以能量水平施加，持续时间足以切割通过血管壁的细长狭缝，其中细长的电外科切割电极被施加到血管壁的表面。

60. 发明申请

US20100004708A1 METHOD AND SYSTEM FOR NERVE STIMULATION AND CARDIAC SENSING PRIOR TO AND DURING A MEDICAL PROCEDURE 有权
标题翻译：在医疗过程中和之后进行神经刺激和心脏感知的方法和系统
公开(公告)号：US20100004708A1
公开(公告)日：2010-01-07
申请号：US12557950
申请日：2009-09-11
申请人： Scott E. Jahns , Michael R.S. Hill , James R. Keogh
发明人： Scott E. Jahns , Michael R.S. Hill , James R. Keogh
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/056 , A61N1/36114 , A61N1/362 , A61N1/36514 , A61N1/385 , A61N1/39
摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.
摘要翻译：提供了一种执行诸如手术的医疗程序的方法。刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。医疗程序在心脏或另一个器官上进行。停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。心脏本身也可能被刺激到跳动状态，例如通过起搏。可以继续刺激神经以允许继续医疗程序。也可以在医疗过程中使用用于感测流体或组织的特征的传感器，例如即将收缩的收缩。还提供用于执行医疗程序的系统和设备。

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