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51. 发明授权

US5214061A Method of using p-acylaminophenoxycarbamates and derivatives as analgesics 失效
标题翻译：使用对氨基苯氧基氨基甲酸酯和衍生物作为止痛剂的方法
公开(公告)号：US5214061A
公开(公告)日：1993-05-25
申请号：US837190
申请日：1992-02-18
申请人： Richard C. Allen , Raymond W. Kosley, Jr. , Bettina Spahl
发明人： Richard C. Allen , Raymond W. Kosley, Jr. , Bettina Spahl
IPC分类号： C07C271/40 , C07C271/44 , C07D213/54 , C07D521/00
CPC分类号： C07D231/12 , C07C271/40 , C07C271/44 , C07D213/54 , C07D233/56 , C07D249/08
摘要： This invention relates to p-acylaminophenoxycarbamates having the formula ##STR1## where R.sub.1 and R.sub.2 are each independently hydrogen, loweralkyl, aryl and arylloweralkyl; R.sub.3 is hydrogen, loweralkyl, arylloweralkyl; R.sub.4 is hydrogen, loweralkyl, formyl, alkylcarbonyl, arylloweralkyl, phenylcarbonyl, arylloweralkylcarbonyl, substituted phenylcarbonyl, pyridylcarbonyl, and substituted pyridylcarbonyl with the proviso that if R.sub.4 contains a carbonyl group directly attached to the oxygen of the N-O moiety, R.sub.3 cannot be hydrogen; or R.sub.3 and R.sub.4 taken together from a heterocyclic ring selected from the group consisting of imidazole or loweralkylimidazole; X is hydrogen, halogen, hydroxy, loweralkyl, loweralkoxy, nitro, amino or trifluoromethyl; and p is an integer selected from 0 and 1; the pharmaceutically acceptable acid addition salts thereof, and where applicable, the geometric and stereoisomers and racemic mixtures thereof. The compounds of this invention display utility as analgesics.
摘要翻译：本发明涉及具有式“IMAGE”的对酰氨基苯氧基氨基甲酸酯，其中R 1和R 2各自独立地为氢，低级烷基，芳基和芳基低级烷基; R3是氢，低级烷基，芳基低级烷基; R4是氢，低级烷基，甲酰基，烷基羰基，芳基低级烷基，苯基羰基，芳基低级烷基羰基，取代的苯基羰基，吡啶基羰基和取代的吡啶基羰基，条件是如果R4含有直接键合在N-O部分的氧上的羰基，则R3不能是氢; 或者R 3和R 4一起选自咪唑或低级烷基咪唑的杂环; X是氢，卤素，羟基，低级烷基，低级烷氧基，硝基，氨基或三氟甲基; 并且p是选自0和1的整数; 其药学上可接受的酸加成盐，以及适用的几何和立体异构体及其外消旋混合物。本发明化合物显示出作为止痛剂的效用。

52. 发明授权

US5106533A Pigment dispersions 失效
标题翻译：颜料分散体
公开(公告)号：US5106533A
公开(公告)日：1992-04-21
申请号：US669884
申请日：1991-03-14
申请人： William A. Hendrickson , Robin E. Wright , Richard C. Allen , James A. Baker , William M. Lamanna
发明人： William A. Hendrickson , Robin E. Wright , Richard C. Allen , James A. Baker , William M. Lamanna
IPC分类号： B01F3/04 , B01F3/06 , B01F13/10 , C09B67/20 , C09B67/46 , C09C3/00 , C09D17/00
CPC分类号： B82Y30/00 , B01F3/04439 , B01F3/06 , C09B67/0069 , C09B67/0091 , C09C3/006 , C09D17/00 , B01F2013/1052 , B01F2215/005 , C01P2002/84 , C01P2004/04 , C01P2004/10 , C01P2004/51 , C01P2004/52 , C01P2004/62 , C01P2004/64 , C01P2004/80 , C01P2006/60 , C01P2006/80
摘要： A dispersion and a method therefor wherein the dispersion has composition A or B, whereinA is a nonaqueous dispersion comprising pigment particles having an average size of less than 0.1 micrometer dispersed in an organic medium, andB is an aqueous dispersion comprising certain classes of inorganic pigment particles having an average size of less than 0.1 micrometer dispersed in an aqueous medium, wherein said classes of inorganic pigment particles are selected from the group consisting of metal oxides and metal salts.The method of the invention comprises the steps of vaporizing a pigment or pigment precursor in the presence of a nonreactive gas stream to provide ultrafine pigment or pigment percursor particles, when pigment precursor particles are present, providing a second gas capable of reacting with said ultrafine pigment precursor particles and reacting said second gas with said ultrafine pigment precursor particles to provide ultrafine pigment particles, transporting said ultrafine pigment particles in said gas stream to a dispersing medium, to provide a dispersion of pigment particles in said medium.
摘要翻译：一种分散体及其方法，其中分散体具有组合物A或B，其中A是包含分散在有机介质中的平均尺寸小于0.1微米的颜料颗粒的非水分散体，B是包含某些类别的无机分散在水性介质中的平均粒度小于0.1微米的颜料颗粒，其中所述类别的无机颜料颗粒选自金属氧化物和金属盐。本发明的方法包括以下步骤：在存在无反应性气流的情况下，使颜料或颜料前体蒸发以提供超细颜料或颜料质量粒子，当存在颜料前体颗粒时，提供能够与所述超细颜料反应的第二气体前体颗粒并使所述第二气体与所述超细颜料前体颗粒反应以提供超细颜料颗粒，将所述气流中的所述超细颜料颗粒输送到分散介质中，以提供颜料颗粒在所述介质中的分散体。

53. 发明授权

US5030669A Pigment dispersions 失效
标题翻译：颜料分散体
公开(公告)号：US5030669A
公开(公告)日：1991-07-09
申请号：US524665
申请日：1990-05-15
申请人： William A. Hendrickson , Robin E. Wright , Richard C. Allen , James A. Baker , William M. Lamanna
发明人： William A. Hendrickson , Robin E. Wright , Richard C. Allen , James A. Baker , William M. Lamanna
IPC分类号： B01F3/04 , B01F3/06 , B01F13/10 , C09B67/20 , C09B67/46 , C09C3/00 , C09D17/00
CPC分类号： B82Y30/00 , B01F3/04439 , B01F3/06 , C09B67/0069 , C09B67/0091 , C09C3/006 , C09D17/00 , B01F2013/1052 , B01F2215/005 , C01P2002/84 , C01P2004/04 , C01P2004/10 , C01P2004/51 , C01P2004/52 , C01P2004/62 , C01P2004/64 , C01P2004/80 , C01P2006/60 , C01P2006/80 , Y10S516/924
摘要： A dispersion and a method therefor wherein the dispersion has composition A or B, whereinA is a nonaqueous dispersion comprising pigment particles having an average size of less than 0.1 micrometer dispersed in an organic medium, andB is an aqueous dispersion comprising certain classes of inorganic pigment particles having an average size of less than 0.1 micrometer dispersed in an aqueous medium, wherein said classes of inorganic pigment particles are selected from the group consisting of metal oxides and metal salts.The method of the invention comprises the steps of vaporizing a pigment or pigment precursor in the presence of a nonreactive gas stream to provide ultrafine pigment or pigment precursor particles, when pigment precursor particles are present, providing a second gas capable of reacting with said ultrafine pigment precursor particles and reacting said second gas with said ultrafine pigment precursor particles to provide ultrafine pigment particles, transporting said ultrafine pigment particles in said gas stream to a dispersing medium, to provide a dispersion of pigment particles in said medium.
摘要翻译：一种分散体及其方法，其中分散体具有组合物A或B，其中A是包含分散在有机介质中的平均尺寸小于0.1微米的颜料颗粒的非水分散体，B是包含某些类别的无机分散在水性介质中的平均粒度小于0.1微米的颜料颗粒，其中所述类别的无机颜料颗粒选自金属氧化物和金属盐。本发明的方法包括以下步骤：在存在无反应性气流的情况下，使颜料或颜料前体蒸发以提供超细颜料或颜料前体颗粒，当存在颜料前体颗粒时，提供能够与所述超细颜料反应的第二气体前体颗粒并使所述第二气体与所述超细颜料前体颗粒反应以提供超细颜料颗粒，将所述气流中的所述超细颜料颗粒输送到分散介质中，以提供颜料颗粒在所述介质中的分散体。

54. 发明授权

US5010083A 2,6-methano-1,3-benzodiazocine compounds which have useful pharmaceutical utility 失效
标题翻译：具有有用的药物效用的2,6-亚甲基-1,3-苯并二氮辛腈化合物
公开(公告)号：US5010083A
公开(公告)日：1991-04-23
申请号：US446743
申请日：1989-12-06
申请人： Richard C. Allen , Marc N. Agnew , David M. Fink
发明人： Richard C. Allen , Marc N. Agnew , David M. Fink
IPC分类号： C07D471/08
CPC分类号： C07D471/08
摘要： Novel 2,6-methano-1,3-benzodiazocines, intermediates, processes for the preparation thereof, and methods for alleviating pain and for alleviating various memory dysfunctions characterized by a decreased cholinergic function, such as Alzheimer's disease, utilizing compounds or compositions thereof are disclosed.
摘要翻译：新颖的2,6-亚甲基-1,3-苯并二氮杂环丁烷，中间体，其制备方法，利用化合物或组合物，减轻疼痛和减轻胆碱能功能降低的各种记忆障碍功能如阿尔茨海默病的方法，披露

55. 发明授权

US4977618A Infrared data communications 失效
标题翻译：红外数据通信
公开(公告)号：US4977618A
公开(公告)日：1990-12-11
申请号：US184261
申请日：1988-04-21
申请人： Richard C. Allen
发明人： Richard C. Allen
IPC分类号： H04B10/20 , H04B10/10 , H04B10/105 , H04B10/22
CPC分类号： H04B10/1149 , H04B10/40
摘要： The present invention is an apparatus for wireless communications of information between two locations. A transmitter means modulates the information into infrared radiation at a first location. The infrared radiation is transmitted by the transmitter to a reflecting surface along a straight line path which is transparent to the infrared radiation. The infrared radiation is reflected at the reflecting surface forming reflected infrared radiation. A receiver means for receiving the reflected infrared radiation from the reflecting surface is positioned at a second location. The second location and the reflecting surface have a straight line path therebetween which is transparent to the infrared radiation.

56. 发明授权

US4578394A Cholinergic function increasing 3-[N-(pyridyl) carbamoyl]-1,4-dihydropyridines 失效
标题翻译：胆碱功能增加3- [N-（吡啶基）氨基甲酰基] -1,4-二氢吡啶
公开(公告)号：US4578394A
公开(公告)日：1986-03-25
申请号：US680036
申请日：1984-12-10
申请人： Richard C. Allen , Richard C. Effland , Joseph T. Klein
发明人： Richard C. Allen , Richard C. Effland , Joseph T. Klein
IPC分类号： C07D213/82 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4425 , A61K31/4427 , A61K31/445 , A61P25/28 , C07D401/12 , A61K31/455
CPC分类号： C07D401/12
摘要： This invention relates to 1,4 dihydropyridines having the following formula ##STR1## wherein R is loweralkyl or Arloweralkyl; R.sub.1, R.sub.2 and R.sub.3 may be the same or different and are hydrogen, loweralkyl or halogen; X is hydrogen, NH.sub.2, ##STR2## and R.sub.4 is hydrogen or loweralkyl. The compounds of this invention display utility in the treatment of Alzheimer's disease and related cognitive disorders characterized by centrally deficient cholinergic function.
摘要翻译：本发明涉及具有下式的其中R为低级烷基或低级烷基的1,4-二氢吡啶; R 1，R 2和R 3可以相同或不同，为氢，低级烷基或卤素; X是氢，NH 2，R 3和R 4是氢或低级烷基。本发明的化合物可用于治疗阿尔茨海默病和以中枢缺乏胆碱能功能为特征的相关认知障碍。

57. 发明授权

US4469869A 3-(4-Piperidinium)-1,2-benzisoxazoles 失效
标题翻译： 3-（4-哌啶鎓）-1,2-苯并异恶唑
公开(公告)号：US4469869A
公开(公告)日：1984-09-04
申请号：US492846
申请日：1983-05-09
申请人： Joseph T. Strupczewski , Beth A. Gardner , Richard C. Allen
发明人： Joseph T. Strupczewski , Beth A. Gardner , Richard C. Allen
IPC分类号： C07D211/28 , C07D211/32 , C07D211/62 , C07D413/04
CPC分类号： C07D413/04 , C07D211/28 , C07D211/32 , C07D211/62
摘要： Novel 3-(4-piperidyl)-1,2-benzisoxazoles, intermediates and processes for the preparation thereof, and methods for alleviating pain utilizing compounds or compositions thereof are disclosed.
摘要翻译：公开了新型3-（4-哌啶基）-1,2-苯并异恶唑，其制备方法及其制备方法，以及利用化合物或其组合物减轻疼痛的方法。

58. 发明授权

US4355037A 3-(4-Piperidyl)-1,2-benzisoxales 失效
标题翻译： 3-（4-哌啶基）-1,2-苯并异恶唑
公开(公告)号：US4355037A
公开(公告)日：1982-10-19
申请号：US319871
申请日：1981-11-12
申请人： Joseph T. Strupczewski , Beth Ann Gardner , Richard C. Allen
发明人： Joseph T. Strupczewski , Beth Ann Gardner , Richard C. Allen
IPC分类号： C07D211/30 , A61K31/445 , A61K31/4465 , A61K31/451 , A61P25/04 , C07D211/28 , C07D211/32 , C07D211/60 , C07D211/62 , C07D413/04 , C07D413/14
CPC分类号： C07D413/04 , C07D211/28 , C07D211/32 , C07D211/62
摘要： Novel 3-(4-piperidyl)-1,2-benzisoxazoles, intermediates and processes for the preparation thereof, and methods for alleviating pain utilizing compounds or compositions thereof are disclosed.
摘要翻译：公开了新型3-（4-哌啶基）-1,2-苯并异恶唑，其制备方法及其制备方法，以及利用化合物或其组合物减轻疼痛的方法。

59. 发明授权

US4153790A 4-Benzyloxy-3-(benzyloxy carbonyl)phenylthioacetmorpholide 失效
标题翻译： 4-苄氧基-3-（苄氧羰基）苯硫基乙酰吗啉
公开(公告)号：US4153790A
公开(公告)日：1979-05-08
申请号：US939177
申请日：1978-09-05
申请人： Arthur R. McFadden , Richard C. Allen , Thomas B. K. Lee
发明人： Arthur R. McFadden , Richard C. Allen , Thomas B. K. Lee
IPC分类号： A61K31/335 , A61P25/04 , A61P29/00 , C07D295/185 , C07D313/12 , C07D295/18
CPC分类号： C07D295/185 , C07D313/12
摘要： A process, and intermediates for the preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid are described. The acid possesses antiinflammatory and analgesic activity.
摘要翻译：描述了制备6,11-二氢-11-氧代二苯并[b，e]氧杂七环素-2-乙酸的方法和中间体。酸具有抗炎和镇痛作用。

60. 发明授权

US07110072B2 Compensators for liquid crystal displays 有权
标题翻译：液晶显示器补偿器
公开(公告)号：US07110072B2
公开(公告)日：2006-09-19
申请号：US10767708
申请日：2004-01-29
申请人： Fred J. Roska , Richard C. Allen , Matthew B. Johnson , Steven J. Rhyner , William W. Merrill , Joan M. Strobel , Kevin M. Hamer , Gregory E. Gilligan
发明人： Fred J. Roska , Richard C. Allen , Matthew B. Johnson , Steven J. Rhyner , William W. Merrill , Joan M. Strobel , Kevin M. Hamer , Gregory E. Gilligan
IPC分类号： G02F1/1335
CPC分类号： G02F1/133634 , G02B5/3016 , G02B5/3083
摘要： An optical stack includes a first liquid crystal layer and a j-retarder disposed on the liquid crystal layer. The j-retarder includes a simultaneous biaxially stretched polymeric film being substantially non-absorbing and non-scattering for at least one polarization state of visible light. The j-retarder has x, y, and z orthogonal indices of refraction where at least two of the orthogonal indices of refraction are not equal, an in-plane retardance being 100 nm or less and an absolute value for an out-of-plane retardance being 55 nm or greater.
摘要翻译：光学堆叠包括设置在液晶层上的第一液晶层和j-延迟器。 j型延迟器包括同时双轴拉伸的聚合物膜，其基本上不吸收并且对于至少一种可见光的偏振状态是非散射的。 j延迟器具有x，y和z正交折射率，其中正交折射率中的至少两个不相等，面内延迟为100nm或更小，并且平面外的绝对值延迟为55nm以上。

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