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    • 52. 发明授权
    • Process for preparing 1,2,4-triazole derivatives
    • 制备1,2,4-三唑衍生物的方法
    • US4123437A
    • 1978-10-31
    • US773026
    • 1977-02-28
    • Beat BohnerDag DawesWilly Meyer
    • Beat BohnerDag DawesWilly Meyer
    • C07D249/12C07F9/6518C07F9/65
    • C07F9/65183C07D249/12
    • 1,2,4-TRIAZOLE DERIVATIVES WHICH HAVE PARTICULAR IMPORTANCE AS INTERMEDIATES FOR, E.G., THE PREPARATION OF ACTIVE SUBSTANCES FOR PEST CONTROL, CORRESPONDING TO THE FORMULA ##STR1## wherein R.sup.1 represents an unsubstituted or substituted alkyl, alkenyl, or alkynyl, naphthyl, benzyl, phenylethyl, ##STR2## or phenylpropyl radical, or a mono or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member, or a substituted phenyl radical,And new processes for the preparation of compounds of the formula ##STR3## wherein R represents hydrogen, an optionally substituted alkyl, alkenyl or alkynyl radical, an optionally substituted phenyl, naphthyl, benzyl, phenylethyl or phenylpropyl radical, a mono- or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member and/or be substituted by alkyl, or a partially hydrogenated naphthyl radical, which processes are performed by addition to a hydrazine of the formulaR -- NH--NH.sub.2or to a hydrazone of the formula ##STR4## wherein R has the above given meaning, R.sub.1 represents hydrogen or lower alkyl and R.sub.2 represents lower alkyl, of an alkoxy-carbonyl-isothiocyanate of the formulaalkyl--O--CO--NCSand subsequent closure of the triazole ring in the resulting thiosemicarbazide of the formula ##STR5## by the splitting-off of an alkanol (alkyl--OH), are disclosed.
    • 具有特异性重要性的1,2,4-三唑衍生物作为EG的中间体,用于制备用于病虫害控制的活性物质,对应于本发明的化合物,其中R 1表示未取代或取代的烷基,烯基或炔基,萘基, 苄基,苯基乙基,苯丙基或可以通过亚烷基桥基或取代的苯基结合的单环或多环环烷基,以及用于制备化合物的新方法 其中R表示氢,任选取代的烷基,烯基或炔基,任选取代的苯基,萘基,苄基,苯基乙基或苯基丙基,可以通过亚烷基桥连接体和/或 被烷基或部分氢化的萘基取代,该方法通过加入式R-NH-NH 2的肼或加成式的腙进行 其中R具有上述给定含义,R 1表示氢或低级烷基,R 2表示低级烷基,式ALKYL-O-CO-NCS的烷氧羰基 - 异硫氰酸酯,随后在三 公开了通过分解链烷醇(烷基-OH)得到的式“IMAGE”的氨基硫脲。
    • 57. 发明授权
    • 1,5-diphenylpyrazole-3-carboxylic acid derivatives for the protection of
cultivated plants
    • 1,5-二苯基吡唑-3-羧酸衍生物,用于保护栽培植物
    • US4944790A
    • 1990-07-31
    • US325833
    • 1989-03-20
    • Hans MoserBeat BohnerWerner Fory
    • Hans MoserBeat BohnerWerner Fory
    • C07F7/18A01N25/04A01N25/32A01N43/40A01N43/56A01P13/00C07D231/14C07D401/12C07D405/12C07D409/12C07D417/12C07D487/04C07D521/00
    • C07D231/12A01N25/32C07D231/14C07D233/56C07D249/08C07D401/12C07D405/12C07D409/12C07D417/12C07D487/04
    • 1,5-diphenylpyrazole-3-carboxylic acid derivatives of the formula ##STR1## in which each of R.sub.a and R.sub.b, independently of the other represents halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -haloalkyl, C.sub.2 -C.sub.5 -alkenyl, C.sub.2 -C.sub.5 -alkynyl or cyano, n represents zero or an integer from 1 to 3, and OR.sub.1 represents hydroxy, a plant-physiologically tolerable salt radical or any desired ester radical, are capable of antagonizing specifically the phytotoxic action of phenoxypropionic acid ester herbicides of the formula II ##STR2## in which G represents ##STR3## in which Hal.sub.1 represents fluorine, chlorine, bromine, iodine or trifluoromethyl, Hal.sub.2 represents hydrogen, fluorine, chlorine, bromine or trifluoromethyl, Z represents nitrogen or methine (--CH.dbd.), X represents an oxygen or sulphur atom, R.sub.1 ' represents halogen, trifluoromethyl, nitro, cyano, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy and n represents 0, 1, 2 or 3 and T represents an ester, amide, cyanamide or oxime radical.Compositions, containing those components, as selective herbicides and the use of those two active ingredients for controlling weeds in crops of useful plants are described, as are also novel 1,5-diphenylpyrazole-3-carboxylic acid derivatives corresponding to the formula I and the preparation thereof.
    • 其中R a和R b各自独立地表示卤素,C 1 -C 5 - 烷基,C 1 -C 5 - 卤代烷基,C 2 -C 5 - 烯基的1,5-二苯基吡唑-3-羧酸衍生物 ,C 2 -C 5炔基或氰基,n表示0或1至3的整数,OR 1表示羟基,植物 - 生理上可耐受的盐基或任何所需的酯基,能够特异性地拮抗苯氧基丙酸酯的植物毒性作用 其中G代表其中Hal1代表氟,氯,溴,碘或三氟甲基的式Ⅱ的除草剂,其中G代表氢,氯,溴,碘或三氟甲基,Hal2代表氢,氟,氯,溴或三氟甲基,Z 表示氮或次甲基(-CH =),X表示氧或硫原子,R1'表示卤素,三氟甲基,硝基,氰基,C1-C4-烷基或C1-C4-烷氧基,n表示0,1,2或3 T代表酯,酰胺,氰胺或肟基。 描述了含有这些成分的作为选择性除草剂的组合物以及这两种活性成分用于控制有用植物作物中的杂草的用途,以及对应于式I的新的1,5-二苯基吡唑-3-羧酸衍生物和 的制备。
    • 58. 发明授权
    • Aminopyrazinones and aminotriazinones of the formula
    • 氨基吡嗪酮和氨基三嗪酮的配方
    • US4940482A
    • 1990-07-10
    • US394389
    • 1989-08-15
    • Beat BohnerWilly Meyer
    • Beat BohnerWilly Meyer
    • A01N47/36C07D241/20C07D253/06C07D253/07C07D253/075C07D401/12C07D409/12C07D521/00
    • C07D521/00A01N47/36C07D241/20C07D253/07C07D253/075
    • Aminopyrazinones and aminotriazinones of the formula ##STR1## and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and post-emergent selective herbicidal and growth-regulating properties. In this formula, E is .dbd.CR.sup.4 --, R.sup.1 is C.sub.1 -C.sub.4 -alkyl, R.sup.2 is C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.1 -C.sub.3 -alkylsulfinyl, C.sub. 1 -C.sub.2 -alkoxyethoxy, C.sub.1 -C.sub.3 -alkylsulfonyl or --NR.sup.5 R.sup.6, R.sup.3 is hydrogen or C.sub.1 -C.sub.3 -alkyl and Q is a group ##STR2## in which R.sup.4 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, cyclopropyl, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.2 -C.sub.4 -alkoxyalkyl, C.sub.3 -C.sub.5 -dialkoxymethyl, halogen or --NR.sup.5 R.sup.6, R.sup.5 and R.sup.6 independently of one another are hydrogen or C.sub.1 -C.sub.3 -alkyl, X is oxygen or sulfur and A is a group ##STR3## in which Y is oxygen, sulfur, --CH.dbd.CH--, --NR.sup.9 -- or --CR.sup.10 .dbd.N--, R.sup.7 is hydrogen, halogen, C.sub. 1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro or trifluoromethyl, R.sup.8 is hydrogen, halogen, C.sub. 1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro, --C.tbd.CH, or one of the groups ##STR4## R.sup.9 and R.sup.10 independently of one another are hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.2 -C.sub.4 -alkenyl, R.sup.11 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.3 -C.sub.6 -cycloalkyl or C.sub.2 -C.sub.4 -alkoxyalkyl, R.sup.12 is C.sub.1 -C.sub.6 -alkoxy, C.sub. 3 -C.sub.6 -alkenyloxy, C.sub.3 -C.sub.6 -alkinyloxy, C.sub.2 -C.sub.6 -halo-genoalkoxy, C.sub.1 -C.sub.4 -cyanoalkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.3 -C.sub.6 -alkenylthio, C.sub.3 -C.sub.6 -alkenylthio, C.sub.5 -C.sub.6 -cycloalkoxy, C.sub.2 -C.sub.6 -alkoxyalkoxy or --NR.sup.16 R.sup.17, R.sup.13 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.14 is hydrogens C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.15 is C.sub.3 -C.sub.6 -alkinyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.2 -C.sub.4 -halogenoalkenyl or C.sub.1 -C.sub.4 -alkyl, substituted by cyano, methoxy, ethoxy, nitro, C.sub.1 -C.sub.4 -alkoxycarbonyl, methylthio, ethylthio, methylsulfonyl or ethylsulfonyl; or C.sub.3 -C.sub.4 -alkenyl substituted by nitro, cyano, methoxy or ethoxy, R.sup.16 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.17 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.18 is C.sub.1 -C.sub.3 -alkyl and C.sub.1 -C.sub.3 -halogenoalkyl, W is oxygen or sulfur, Z is oxygen, sulfur, --SO-- or --So.sub.2 -- and m is the number zero or one.
    • 59. 发明授权
    • Aminopyrazinones and aminotriazinones
    • 氨基吡嗪酮和氨基三嗪酮
    • US4920223A
    • 1990-04-24
    • US384956
    • 1989-07-25
    • Beat BohnerWilly Meyer
    • Beat BohnerWilly Meyer
    • A01N47/36C07D241/20C07D253/06C07D253/07C07D253/075C07D401/12C07D409/12C07D521/00
    • C07D521/00A01N47/36C07D241/20C07D253/07C07D253/075
    • Aminopyrazinones and aminotriazinones of the formula I ##STR1## and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and post-emergent selective herbicidal and growth-regulating properties. In this formula, E is nitrogen or .dbd.CR.sup.4 --, R.sup.1 is C.sub.1 -C.sub.4 -alkyl, R.sup.2 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.1 -C.sub.3 -alkylsulfinyl, C.sub.1 -C.sub.2 -alkoxyethoxy, C.sub.1 -C.sub.3 -alkylsulfonyl, halogen or --NR.sup.5 R.sup.6, R.sup.3 is hydrogen or C.sub.1 -C.sub.3 -alkyl and Q is a group ##STR2## in which R.sup.4 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, cyclopropyl, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.2 -C.sub.4 -alkoxyalkyl, C.sub.3 -C.sub.5 -dialkoxymethyl, halogen or --NR.sup.5 R.sup.6, R.sup.5 and R.sup.6 independently of one another are hydrogen or C.sub.1 -C.sub.3 -alkyl, X is oxygen or sulfur and A is a group ##STR3## in which Y is oxygen, sulfur, --CH.dbd.CH--, --NR.sup.9 -- or --CR.sup.10 .dbd.N--, R.sup.7 is hydrogen, halogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro or trifluoromethyl, R.sup.8 is hydrogen, halogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro, --C.tbd.CH, or one of the groups ##STR4## R.sup.9 and R.sup.10 independently of one another are hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.2 -C.sub.4 -alkenyl, R.sup.11 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.3 -C.sub.6 -cycloalkyl or C.sub.2 -C.sub.4 -alkoxyalkyl, R.sup.12 is C.sub.1 -C.sub.6 -alkoxy, C.sub.3 -C.sub.6 -alkenyloxy, C.sub.3 -C.sub.6 -alkinyloxy, C.sub.2 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.4 -cyanoalkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.3 -C.sub.6 -alkenylthio, C.sub.3 -C.sub.6 -alkinylthio, C.sub.5 -C.sub.6 -cycloalkoxy, C.sub.2 -C.sub.6 -alkoxyalkoxy or --NR.sup.16 R.sup.17, R.sup.13 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.14 is hydrogens C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.15 is C.sub.3 -C.sub.6 -alkinyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub. 2 -C.sub.4 -halogenoalkenyl or C.sub.1 -C.sub.4 -alkyl, subsituted by cyano, methoxy, ethoxy, nitro, C.sub.1 -C.sub.4 -alkoxycarbonyl, methylthio, ethylthio, methylsulfonyl or ethylsulfonyl; or C.sub.3 -C.sub.4 -alkenyl substituted by nitro, cyano, methoxy or ethoxy, R.sup.16 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.17 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.18 is C.sub.1 -C.sub.3 -alkyl and C.sub.1 -C.sub.3 -halogenoalkyl, W is oxygen or sulfur, Z is oxygen, sulfur, --SO-- or --SO.sub.2 -- and m is the number zero or one.
    • 60. 发明授权
    • Aminopyrazinones and aminotriazinones
    • US4795486A
    • 1989-01-03
    • US99036
    • 1987-09-21
    • Beat BohnerWilly Meyer
    • Beat BohnerWilly Meyer
    • A01N47/36C07D241/20C07D253/06C07D253/07C07D253/075C07D401/12C07D409/12C07D521/00A01N43/707
    • C07D521/00A01N47/36C07D241/20C07D253/07C07D253/075
    • Aminopyrazinones and aminotriazinones of the formula ##STR1## and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and post-emergent selective herbicidal and growth-regulating properties. In this formula, E is nitrogen or .dbd.CR.sup.4 --, R.sup.1 is C.sub.1 -C.sub.4 -alkyl, R.sup.2 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.1 -C.sub.3 -alkylsulfinyl, C.sub.1 -C.sub.2 -alkoxyethoxy, C.sub.1 -C.sub.3 -alkylsulfonyl, halogen or --NR.sup.5 R.sup.6, R.sup.3 is hydrogen or C.sub.1 -C.sub.3 -alkyl and Q is a group ##STR2## in which R.sup.4 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.1 -C.sub.3 -alkoxy, cyclopropyl, C.sub.1 -C.sub.3 -halogenoalkoxy, C.sub.1 -C.sub.3 -alkylthio, C.sub.2 -C.sub.4 -alkoxyalkyl, C.sub.3 -C.sub.5 -dialkoxymethyl, halogen or --NR.sup.5 R.sup.6, R.sup.5 and R.sup.6 independently of one another are hydrogen or C.sub.1 -C.sub.3 -alkyl, X is oxygen or sulfur and A is a group ##STR3## in which Y is oxygen, sulfur, --CH.dbd.CH--, --NR.sup.9 -- or --CR.sup.10 .dbd.N--, R.sup.7 is hydrogen, halogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro or trifluoromethyl, R.sup.8 is hydrogen, halogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -alkoxy, nitro, --C.dbd.CH, or one of the groups ##STR4## R.sup.9 and R.sup.10 independently of one another are hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.2 -C.sub.4 -alkenyl, R.sup.11 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -halogenoalkyl, C.sub.3 -C.sub.6 -cycloalkyl or C.sub.2 -C.sub.4 -alkoxyalkyl, R.sup.12 is C.sub.1 -C.sub.6 -alkoxy, C.sub.3 -C.sub.6 -alkenyloxy, C.sub.3 -C.sub.6 -alkinyloxy, C.sub.2 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.4 -cyanoalkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.3 -C.sub.6 -alkenylthio, C.sub.3 -C.sub.6 -alkinylthio, C.sub.5 -C.sub.6 -cycloalkoxy, C.sub.2 -C.sub.6 -alkoxyalkoxy or --NR.sup.16 R.sup.17, R.sup.13 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.14 is hydrogens C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.15 is C.sub.3 -C.sub.6 -alkinyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub. 2 -C.sub.4 -halogenoalkenyl or C.sub.1 -C.sub.4 -alkyl, substituted by cyano, methoxy, ethoxy, nitro, C.sub.1 -C.sub.4 -alkoxycarbonyl, methylthio, ethylthio, methylsulfonyl or ethylsulfonyl; or C.sub.3 -C.sub.4 -alkenyl substituted by nitro, cyano, methoxy or ethoxy, R.sup.16 is hydrogen, C.sub.1 -C.sub.3 -alkyl or C.sub.3 -C.sub.4 -alkenyl, R.sup.17 is hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.3 -cyanoalkyl or C.sub.1 -C.sub.3 -alkoxy, R.sup.18 is C.sub.1 -C.sub.3 -alkyl and C.sub.1 -C.sub.3 -halogenoalkyl, W is oxygen or sulfur, Z is oxygen, sulfur, --SO-- or --SO.sub.2 -- and m is the number zero or one.