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51. 发明授权

US07622112B2 Anti-SARS monoclonal antibodies 有权
标题翻译：抗SARS单克隆抗体
公开(公告)号：US07622112B2
公开(公告)日：2009-11-24
申请号：US10581613
申请日：2004-12-06
申请人： Jody Berry , Steven Jones , Xin Yong Yuan , Mike Gubbins , Anton Andonov , Hana Weingartl , Mike Drebot , Frank Plummer
发明人： Jody Berry , Steven Jones , Xin Yong Yuan , Mike Gubbins , Anton Andonov , Hana Weingartl , Mike Drebot , Frank Plummer
IPC分类号： A61K39/42 , C12N15/09 , C12N15/13 , C12P21/08 , C12P21/00 , C07K16/10 , C07K16/46
CPC分类号： C07K16/10 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/76 , G01N33/56983
摘要： Monoclonal antibody reagents that recognize the SARS-coronavirus (SARS-HCoV) are needed urgently. In this report we describe the development and immunochemical characterization of mAbs against the SARS-HCoV based upon their specificity, binding requirements, and biological activity. Initial screening by ELISA, using highly purified virus as the coating antigen, resulted in the selection of seventeen mAbs. Five mAbs exhibited Western immunoblot reactivity with the denatured spike protein, of which two demonstrated the ability to neutralize SARS-HCoV in vitro. Another four Western immunoblot-negative mAbs also neutralize the virus. These antibodies will be useful for the development of diagnostic tests, pathogenicity and vaccine studies.
摘要翻译：迫切需要识别SARS冠状病毒（SARS-HCoV）的单克隆抗体试剂。在本报告中，我们根据其特异性，结合要求和生物活性，描述mAb对SARS-HCoV的发展和免疫化学表征。通过ELISA进行初步筛选，使用高度纯化的病毒作为包被抗原，导致17个mAb的选择。 5个mAb显示出与变性穗蛋白的Western免疫印迹反应性，其中两个显示出在体外中和SARS-HCoV的能力。另外四种Western免疫印迹阴性mAb也中和了病毒。这些抗体可用于诊断测试，致病性和疫苗研究的开发。

52. 发明申请

US20090153483A1 AMBIDEXTROUS OPERATED MOUSE 审中-公开
标题翻译： AMBIDEXTROUS操作鼠标
公开(公告)号：US20090153483A1
公开(公告)日：2009-06-18
申请号：US12261011
申请日：2008-10-29
申请人： YI-FENG WENG , SHIH-FANG WONG , BING LI , YONG YUAN
发明人： YI-FENG WENG , SHIH-FANG WONG , BING LI , YONG YUAN
IPC分类号： G06F3/033
CPC分类号： G06F3/0383 , G06F3/03543 , G06F2203/0332
摘要： A method for operating the mouse adapted for right-handed or left-handed includes storing a default operation mode and a current operation mode of the mouse; generating button signals according to click operations exerted on buttons of the mouse; obtaining the current operation mode and the default operation mode; changing the button signals on condition that the default operation mode is different from the current operation mode; and sending the changed button signals to an external computer. A mouse adapted for use by either right-handed or left-handed persons is also provided.
摘要翻译：适用于右手或左手的操作鼠标的方法包括存储鼠标的默认操作模式和当前操作模式; 根据施加在鼠标的按钮上的点击操作产生按钮信号; 获取当前操作模式和默认操作模式; 在默认操作模式与当前操作模式不同的情况下更改按钮信号; 并将改变的按钮信号发送到外部计算机。还提供了适合右手或左撇子使用的鼠标。

53. 发明授权

US6142766A Safety lighter 有权
标题翻译：安全打火机
公开(公告)号：US6142766A
公开(公告)日：2000-11-07
申请号：US389693
申请日：1999-10-14
申请人： Yong Yuan Hu
发明人： Yong Yuan Hu
IPC分类号： F23Q2/28
CPC分类号： F23Q2/287
摘要： A piezoelectric lighter incorporates with a safety device which includes a pusher cap slidably mounted on a pusher cavity of a casing in a vertically movable manner and attached to a top end of a piezoelectric unit; a locking member fitting on an upper portion of the casing, wherein the locking member having a stopper latch locking up the pusher cap for blocking the pusher cap in a vertical manner. The safety device further includes a resilient unit, which is articulated on an axle mounted on the upper portion of the casing, normally urging and retaining the locking member locking up the pusher cap so as to block any downwardly movement of the pusher cap and thus prevent the ignition operation of the piezoelectric unit. Thereby, in order to ignite the piezoelectric lighter, the locking member must be pressed transversely inward to move the latch of the locking member out of the edge of the cap body of the pusher cap. Once in this position, the pusher cap can be pressed downward to compress the piezoelectric unit to ignite the lighter.
摘要翻译：一种压电打火机包括安全装置，该安全装置包括可滑动地安装在壳体的推动器腔中的推动器盖，其可垂直移动并附接到压电单元的顶端; 锁定构件，其配合在所述壳体的上部，其中所述锁定构件具有止动器闩锁，所述止动器闩锁锁定所述推动器盖，以垂直方式阻止所述推动器盖。该安全装置还包括弹性单元，该弹性单元铰接在安装在壳体上部的轴上，通常推动并保持锁定构件锁定推动器盖，以阻止推动器盖的任何向下移动，从而防止压电单元的点火操作。因此，为了点燃压电打火机，锁定构件必须被横向向内按压，以将锁定构件的闩锁移出推动器盖的盖体的边缘。一旦处于该位置，可以向下按压推动器盖以压缩压电单元以点燃打火机。

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