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51. 发明申请

US20200181133A1 PROCESS FOR THE PREPARATION OF ALECTINIB 审中-公开
公开(公告)号：US20200181133A1
公开(公告)日：2020-06-11
申请号：US16705275
申请日：2019-12-06
申请人： FRESENIUS KABI IPSUM S.R.L. , Alma Mater Studiorum - Università di Bologna
发明人： Walter CABRI , Alessandra TOLOMELLI , Assunta DE NISI , Lucia FERRAZZANO
IPC分类号： C07D413/14
摘要： The present invention relates to a process for preparing alectinib, or a pharmaceutically acceptable salt thereof, and to related intermediates.

52. 发明授权

US10464049B2 Process to synthesize a catalyst performing water-gas shift reaction at a high temperature 有权
公开(公告)号：US10464049B2
公开(公告)日：2019-11-05
申请号：US15611861
申请日：2017-06-02
申请人： L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude , Alma Mater Studiorum Università di Bologna
发明人： Raphaël Faure , Giuseppe Fornasari , Daniel Gary , Carlo Lucarelli , Nicola Schiaroli , Angelo Vaccari
IPC分类号： B01J23/825 , B01J23/00 , B01J23/80 , B01J23/83 , B01J37/02 , B01J37/03 , B01J37/06 , B01J37/08 , C01B3/58 , B01J21/04 , B01J35/00 , B01J35/10 , B01J37/00
摘要： A process to synthesize a catalyst performing Water-Gas shift reaction at a temperature more than 300° C. using a precursor having general formula [(Cu, Zn)1-x (Al, M)x (OH)2]x+ (An−x/n).kH2O with M=Al, La, Ga or In, A=CO3, 0.33

53. 植物专利

USPP29765P3 Cherry tree named ‘PA7UNIBO’ 有权
公开(公告)号：USPP29765P3
公开(公告)日：2018-10-23
申请号：US15330889
申请日：2016-11-14
申请人： ALMA MATER STUDIORUM-UNIVERSITÀ DI BOLOGNA
发明人： Stefano Lugli , Riccardo Correale , Michelangelo Grandi
IPC分类号： A01H5/08
摘要： Variety Denomination ‘PA7UNIBO’ is a novel cherry tree derived from a seedling of unknown cross which was planted at Vignola, Modena Province, Italy. The genus and species (cultivar) of ‘PA7UNIBO’ is Prunus avium. It was initially propagated by grafting to root stocks of varying vigor and, after testing in districts and plantings of differing types, proved to have qualities for a promising new cultivar for the market.

54. 发明申请

US20170027689A1 HEART VALVE PROSTHESIS WITH INTEGRATED ELECTRONIC CIRCUIT FOR MEASURING INTRAVALVULAR ELECTRICAL IMPEDANCE, AND SYSTEM FOR MONITORING FUNCTIONALITY OF THE PROSTHESIS 有权
标题翻译：用于测量异常电气阻抗的集成电子电路的心脏瓣膜和用于监测预防功能的系统
公开(公告)号：US20170027689A1
公开(公告)日：2017-02-02
申请号：US15303414
申请日：2015-04-15
申请人： ALMA MATER STUDIORUM - UNIVERSITÀ DI BOLOGNA
发明人： Emanuela Marcelli
IPC分类号： A61F2/24 , A61B5/00 , G06F19/00 , A61B5/02
CPC分类号： A61F2/2403 , A61B5/0031 , A61B5/02028 , A61B5/0538 , A61B5/4836 , A61B5/686 , A61B5/6869 , A61B5/7246 , A61B5/7282 , A61F2250/0002 , A61F2250/0096 , G06F19/00 , G06F19/3418 , G16H40/67
摘要： A heart valve prosthesis of any type, with internal microelectronic circuit for monitoring the movement of the valve leaflets or of the movable opening and closing elements of said heart valve prosthesis, and external electronic system for telemetric monitoring of such a sensorized heart valve prosthesis, characterized in that said heart valve prosthesis comprises two or more electrodes set in the annular base body of the prosthesis itself, and comprises an internal microelectronic circuit, which is connected to electric power supply means, is equipped with means for generating, between said electrodes, an electrical field, the field lines of which are oriented so as to interfere with the opening and closing movement of the movable elements of said heart valve prosthesis or of the natural leaflets of the heart valve on which said prosthesis will be mounted, and is equipped with or connected to means for detecting the variations of said electrical field produced by the cyclic movement of opening or closing of said leaflets or of said movable elements, which will be expressed as variations of intravalvular electrical impedance and characterized in that it comprises, implanted, a transceiver unit with corresponding antenna for telemetric transmission of the data correlated to said variations of intravalvular electrical impedance, to an external unit that processes the collected data and uses them at least for purposes of diagnosis and prevention.
摘要翻译：一种任何类型的心脏瓣膜假体，具有用于监测瓣膜小叶或所述心脏瓣膜假体的可动开闭元件的运动的内部微电子电路，以及用于这种传感心脏瓣膜假体的遥测监测的外部电子系统，其特征在于因为所述心脏瓣膜假体包括设置在假体本身的环形基体中的两个或更多个电极，并且包括连接到电力供应装置的内部微电子电路，其具有用于在所述电极之间产生一个电场，其场线被定向成干扰所述心脏瓣膜假体的可移动元件或将安装所述假体的心脏瓣膜的天然传单的开启和关闭运动，并且配备有或连接到用于检测由循环运动o产生的所述电场的变化的装置 f所述小叶或所述可移动元件的打开或关闭，其将被表示为血管内电阻抗的变化，并且其特征在于，其包括植入具有相应天线的收发器单元，用于与所述血管内电位变化相关的数据进行遥测传输电气阻抗，到处理收集的数据的外部单元，并至少用于诊断和预防的目的。

55. 发明授权

US09526240B2 Sprayable dispersed starch-based bioplastic formulation to control pests 有权
标题翻译：可喷雾分散的淀粉基生物塑料制剂来控制害虫
公开(公告)号：US09526240B2
公开(公告)日：2016-12-27
申请号：US14276224
申请日：2014-05-13
申请人： The United States of America, as Represented by the Secretary of Agriculture , Alma Mater Studiorum—Università di Bologna
发明人： Hamed K Abbas , Cesare Accinelli
IPC分类号： A01N63/00 , A01N25/10 , A01N63/04 , A01N43/16 , A01N63/02
CPC分类号： A01N25/10 , A01N43/16 , A01N63/02 , A01N63/04
摘要： A sprayable liquid biodegradable formulation comprising biocontrol microorganisms imbedded in a dispersed starch-based bioplastic is effective for delivering biocontrol microorganisms and bioactive compounds to soil, crops and seeds and facilitating positioning of biocontrol agents in close proximity to target pests. After application with conventional spray equipment, water evaporates rapidly and the dispersed bioplastic formula remains, serving as a prolonged growth substrate for the biocontrol microorganisms. Application of the bioplastic dispersion formulation comprising Beauveria bassiana significantly reduced damages caused by the European Corn Borer in corn and the Tarnished Plant Bug in cotton. Applying a formulation of spores of a non-aflatoxigenic A. flavus isolate resulted in a 97% reduction of aflatoxin contamination of corn. The bioplastic dispersion formulation is effective in delivering crystal Bacillus thuringiens endotoxins to European Corn Borer larvae, causing 72% mortality. The sprayable bioplastic formulation protects seeds from soil-borne pathogens, thereby reducing damping-off in tomato plants by up to 85%.
摘要翻译：包含嵌入在分散的淀粉基生物塑料中的生物防治微生物的可喷雾液体可生物降解的制剂有效地将生物防治微生物和生物活性化合物递送到土壤，作物和种子，并促进生物防治剂在目标害虫附近的定位。在用常规喷雾设备应用后，水迅速蒸发，并且分散的生物塑料配方保留，用作生物防治微生物的延长的生长底物。包含白僵菌的生物塑料分散体制剂的应用显着降低了玉米中的欧洲玉米螟和棉花中玷污的植物虫造成的损害。应用非黄曲霉黄曲霉分离物的孢子制剂导致玉米黄曲霉毒素污染降低97％。生物塑料分散体制剂有效地将结晶苏云金芽孢杆菌内毒素输送到欧洲玉米螟幼虫，造成72％的死亡率。可喷洒的生物塑料制剂保护种子免受土壤传播的病原体，从而将番茄植物的阻尼减少高达85％。

56. 植物专利

USPP26989P3 Pear tree named ‘PE3UNIBO’ 有权
标题翻译：梨树名叫“PE3UNIBO”
公开(公告)号：USPP26989P3
公开(公告)日：2016-08-02
申请号：US14121605
申请日：2014-09-24
申请人： Alma Mater Studiorum—Università di Bologna
发明人： Stefano Musacchi , Vincenzo Ancarani , Silviero Sansavini
IPC分类号： A01H5/08
CPC分类号： A01H6/7481 , A01H5/08
摘要： A new and distinct Pyrus communis L. pear tree variety named ‘PE3UNIBO’, is particularly characterized by the following features: medium vigorous and slightly compact trees with upright habitus; bearing habitus normally on spurs on 2-3 years old branches and sometimes on 1 year old shoot; good grafting compatibility with the main quince rootstocks; early medium ripening (about 1-2 days before ‘Bartlett’); high and constant yield; early bearing; good size of fruit (about 200 g), ranging from pyriform to pyriform-elongated shape; green skin until the full ripening stage with a slight russet; tender and juicy white flesh at the full ripening stage with a very good flavor that is slightly sour; long storage capacity in cold room is, until 5 month.
摘要翻译：一种名叫“PE3UNIBO”的新颖而独特的梨属梨树种，其特点是具有以下特点：中等强度和轻微的树木，具有直立的习惯; 轴承习惯通常在2-3岁的枝条上，有时在1岁以上拍摄; 良好的嫁接与主要砧木的兼容性; 早期中成熟（“巴特利特”前约1-2天）; 高和不变的产量; 早期轴承水果尺寸（约200克），从梨形到梨形长条形; 绿色皮肤，直到完成成熟阶段与轻微的russet; 嫩和多汁的白色肉在完全成熟的阶段，味道很好，有点酸; 冷藏室的长存储容量，直到5个月。

57. 发明申请

US20150327540A1 Sprayable Dispersed Starch-based Bioplastic Formulation to Control Pests 有权
标题翻译：可喷雾分散淀粉基生物塑料配方控制害虫
公开(公告)号：US20150327540A1
公开(公告)日：2015-11-19
申请号：US14276224
申请日：2014-05-13
申请人： The United States of America, as Represented by the Secretary of Agriculture , Alma Mater Studiorum- Università di Bologna
发明人： Hamed K Abbas , Cesare Accinelli
IPC分类号： A01N25/10 , A01N43/16 , A01N63/04
CPC分类号： A01N25/10 , A01N43/16 , A01N63/02 , A01N63/04
摘要： A sprayable liquid biodegradable formulation comprising biocontrol microorganisms imbedded in a dispersed starch-based bioplastic is effective for delivering biocontrol microorganisms and bioactive compounds to soil, crops and seeds and facilitating positioning of biocontrol agents in close proximity to target pests. After application with conventional spray equipment, water evaporates rapidly and the dispersed bioplastic formula remains, serving as a prolonged growth substrate for the biocontrol microorganisms. Application of the bioplastic dispersion formulation comprising Beauveria bassiana significantly reduced damages caused by the European Corn Borer in corn and the Tarnished Plant Bug in cotton. Applying a formulation of spores of a non-aflatoxigenic A.flavus isolate resulted in a 97% reduction of aflatoxin contamination of corn. The bioplastic dispersion formulation is effective in delivering crystal Bacillus thuringiens endotoxins to European Corn Borer larvae, causing 72% mortality. The sprayable bioplastic formulation protects seeds from soil-borne pathogens, thereby reducing damping-off in tomato plants by up to 85%.
摘要翻译：包含嵌入在分散的淀粉基生物塑料中的生物防治微生物的可喷雾液体可生物降解的制剂有效地将生物防治微生物和生物活性化合物递送到土壤，作物和种子，并促进生物防治剂在目标害虫附近的定位。在用常规喷雾设备应用后，水迅速蒸发，并且分散的生物塑料配方保留，用作生物防治微生物的延长的生长底物。包含白僵菌的生物塑料分散体制剂的应用显着降低了玉米中的欧洲玉米螟和棉花中玷污的植物虫造成的损害。应用非黄曲霉黄曲霉分离物的孢子制剂导致玉米黄曲霉毒素污染降低97％。生物塑料分散体制剂有效地将结晶苏云金芽孢杆菌内毒素输送到欧洲玉米螟幼虫，造成72％的死亡率。可喷洒的生物塑料制剂保护种子免受土壤传播的病原体，从而将番茄植物的阻尼减少高达85％。

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