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41. 发明授权

US11052205B2 Devices and methods for delivering fluid to a nasal cavity 有权
公开(公告)号：US11052205B2
公开(公告)日：2021-07-06
申请号：US16437551
申请日：2019-06-11
申请人： Neosinus Health Inc
发明人： Kashif Mazhar , Magda R. Pugh , Michael John Clare
IPC分类号： A61M15/08 , A61M15/00 , A61M11/02
摘要： Devices and methods for delivering fluid from a container to the nasal cavity. The device includes a selector and a nozzle that are connected together and rotatable relative to each other. The device includes a curve to overcome anatomical barriers and one or more openings to provide for effective distribution when delivering the fluid to the nasal cavity. The selector includes an opening that aligns with a corresponding opening in a container that holds the fluid. The nozzle includes a first passage with one or more openings on a first lateral side, and a second passage with one or more openings on an opposing second lateral side. The selector and nozzle can be positioned at a first and second rotational positions to selectively deliver the fluid through the first and second passages to the nasal cavity.

42. 发明授权

US10980287B2 Aerosol-generating system and method of dispensing liquid aerosol-forming substrate with pumped air 有权
公开(公告)号：US10980287B2
公开(公告)日：2021-04-20
申请号：US16875355
申请日：2020-05-15
申请人： Mycronic AB
发明人： Ben Mazur , Eva Saade Latorre , Alain Tabasso
IPC分类号： A24F47/00 , F04B19/00 , A61M15/06 , A61M11/02 , F04F5/24 , A61M15/00 , F04B45/047 , F04B43/04 , A61M11/04 , A24F40/48 , H05K13/08 , B65G1/137 , H05K5/00 , H05K13/00 , H05K13/02 , A61M16/00 , H05K13/04 , G06K7/10 , G06K7/14
摘要： An aerosol-generating system may include a liquid storage portion, a vaporizer, and a pump. The liquid storage portion may be configured to store a liquid aerosol-forming substrate. The vaporizer may be configured to volatilize the liquid aerosol-forming substrate. The pump may be configured to pump air into the liquid storage portion so as to push out a volume of the liquid aerosol-forming substrate from the liquid storage portion and to supply the volume of the liquid aerosol-forming substrate to the vaporizer. A method for generating an aerosol may be performed with the system.

43. 发明授权

US10966653B2 Allergen exposure system comprising a chamber for mixing air and allergens, which is separated from the exposure room that accommodates the patients 有权
公开(公告)号：US10966653B2
公开(公告)日：2021-04-06
申请号：US15120407
申请日：2015-02-16
申请人： ALYATEC
发明人： Gérard Santailler
IPC分类号： A61B5/00 , A61M11/06 , A61G10/02 , A61M11/02 , A61M11/00 , A61M16/00
摘要： An allergen exposure system includes a mixing chamber, delimited by walls and distinct from the air inlet duct and from the exposure room in which the patients are situated. A mixing between a stream of allergen particles from an allergen injection device and a flow of air devoid of allergens which has passed through a filtration device, occurs through a phenomenon of microturbulence in this mixing chamber which forms a widening with respect to the air inlet duct and makes it possible to obtain a flow of air laden with allergen particles which is injected into the exposure room through at least one diffusion outlet so that it can be inhaled by the patients. This invention is of benefit to medical and pharmaceutical research in the field of allergy study.

44. 发明授权

US10960156B2 Nebulizer and breath-actuated nebulization method 有权
公开(公告)号：US10960156B2
公开(公告)日：2021-03-30
申请号：US16033513
申请日：2018-07-12
申请人： ENCHANT TEK. CO., LTD.
发明人： Mu-Hua Huang , Chun-Hung Chen , Ling-Ling Leonard Lin
IPC分类号： A61M15/00 , A61M16/20 , A61M11/06 , A61M11/02 , A61M16/00 , B05B1/26 , B05B7/00 , B05B7/24 , B05B7/12 , A61M16/14
摘要： A nebulizer comprises a housing, a closed pressure system, at least one pressure relief mechanism and a nebulization mechanism. The housing comprises a nozzle, and the nozzle comprises an outlet portion and an inlet portion communicated with a pressurized gas source. The closed pressure system comprises at least one gas inlet and a gas outlet. The at least one pressure relief mechanism is disposed on the at least one gas inlet. The nebulization mechanism is capable of moving to a nebulization position. An interior pressure in the closed pressure system is changed by the at least one pressure relief mechanism to control the nebulization mechanism for nebulization.

45. 发明申请

US20210023314A1 INJECTOR AND METHOD OF INJECTING SOLUTION CONTAINING BIOMOLECULES INTO INJECTION TARGET USING THE SAME 有权
公开(公告)号：US20210023314A1
公开(公告)日：2021-01-28
申请号：US16968078
申请日：2019-02-08
申请人： DAICEL CORPORATION
发明人： Katsuya MIKI , Shingo ATOBE , Hiroshi MIYAZAKI , Ayano SUZUKI , Yuko SAKAGUCHI
IPC分类号： A61M11/02 , A61M11/00 , A61M11/06
摘要： This application relates to an injector in which when a solution containing biomolecules is injected into an injection target, a proportion of biomolecules that function in the injection target with respect to the injected biomolecules is large. This application also relates to a method of injecting a solution containing biomolecules into an injection target using the injector. In one aspect, the injector injects the solution containing biomolecules into the injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit and a nozzle unit, wherein the injector satisfies a given condition.

46. 发明授权

US10894133B2 Device for dispensing a fluid product 有权
公开(公告)号：US10894133B2
公开(公告)日：2021-01-19
申请号：US16304025
申请日：2017-06-08
申请人： APTAR FRANCE SAS
发明人： Matthieu Baillet , Dolorès Carballo , Hélène Dulude , Franck Poullain
IPC分类号： A61M11/02 , B05B11/06 , B05B11/00 , A61M15/08 , A61M15/00 , B05B11/02
摘要： A dispenser device for dispensing a fluid or powder composition, the dispenser device comprising: a dispenser head (1) that is provided with a dispenser outlet (10) that is formed at the end of a hollow sleeve (3); an air expeller (20) for generating a flow of air while the device is being actuated, said air expeller including a piston (21) that slides in an air chamber (22) between a rest position and a dispensing position, said air chamber (22) including a cylindrical body in which said piston (21) slides in airtight manner; and a reservoir (30) that contains a single dose of composition, said reservoir (30) including an air inlet (31) that is connected to said air expeller (20), and a composition outlet (32) that is connected to said dispenser outlet (10), said air inlet (31) including a composition retainer member (40) for retaining the composition in the reservoir (30) until the composition is dispensed, and said composition outlet (32) being closed by a closure element (50) that is force fitted in the composition outlet (32) of the reservoir (30); said device further comprising a mechanical opening system (61, 62) that co-operates with said closure element (50) so as to expel it mechanically from its closed position while the device is being actuated; said device further comprising an indicator (100; 50) that, in the rest position before actuation, is in a first state, and that after actuation passes into a second state, the passage from the first to the second state informing the user that the device has been actuated, said first state being a visible state and said second state being a non-visible state, said device including a pusher element (25) that is secured to said piston (21), and on which the user presses during actuation, said dispenser head (1) including a skirt (5) that is arranged around said air chamber (22), said pusher element (25), in its rest position before actuation, projecting axially out from said skirt (5), and after actuation, being arranged inside said skirt (5), said pusher element (25) including an indicator (100) that is visible before actuation and that is not visible after actuation.

47. 发明授权

US10857310B2 Mixing channel for an inhalation device and inhalation device 有权
公开(公告)号：US10857310B2
公开(公告)日：2020-12-08
申请号：US14382392
申请日：2013-03-08
申请人： VECTURA GMBH
发明人： Bernhard Muellinger , Martin Huber , Tobias Kolb , Monika Hartmann
IPC分类号： A61M11/00 , A61M15/00 , A61M11/06 , A61M15/06 , A61M11/02
摘要： The invention relates to a mixing channel for an inhalation device, and in particular to a mixing channel with improved injection and mixing properties for injecting and mixing a liquid drug into an air flow streaming in the mixing channel, thereby producing an aerosol to be inhaled by a patient. One aspect of the invention relates to a mixing channel for an inhalation device, comprising an inlet opening, an outlet opening, and an injection zone located between the inlet opening and the outlet opening, wherein the injection zone has a longitudinal center axis, wherein the injection zone comprises (a) a built-in nebulizer, or (b) a detachable nebulizer, or (c) a member adapted to receive a detachable nebulizer, wherein the effective cross sectional area of the mixing channel in a plane perpendicular to the longitudinal center axis is smaller in the injection zone than upstream of the injection zone.

48. 发明申请

US20200338287A1 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：US20200338287A1
公开(公告)日：2020-10-29
申请号：US16759884
申请日：2018-10-30
申请人： CLEXIO BIOSCIENCES LTD.
发明人： Philip CHAN , Ernest ERDOSI , Alan D. KIRKPATRICK, Jr. , John P. MAJEWSKI , Douglas WEITZEL , Morgan CARLSON , John LONGAN , James RUDOLPH
IPC分类号： A61M15/08 , A61M15/00 , A61M11/02 , A61M25/01 , A61M25/00
摘要： A intranasal device and method for self-administration of a medicament are provided. The intranasal device includes a body, a catheter, a feedback mechanism, and a delivery system. The body has a chamber configured to store the medicament. The body defines a channel that extends from an interior of the body to an exterior of the body. The catheter is configured to be actuated to extend from the body through the channel and is in fluid communication with the chamber. A distal end of the catheter is configured for entry into a nasal passage of a patient. The feedback mechanism is configured to indicate a position of the distal end of the catheter within the nasal passage. The delivery system is configured to deliver the medicament from the chamber into the nasal passage via the catheter.

49. 发明申请

US20200289779A1 NEBULIZER ORIENTATION APPARATUS 审中-公开
公开(公告)号：US20200289779A1
公开(公告)日：2020-09-17
申请号：US16649012
申请日：2018-09-05
申请人： Frank FISH
发明人： Karin-Ann BEN-ISRAEL
IPC分类号： A61M16/08 , A61M11/02 , A61M11/06
摘要： There is provided a nebulizer orientation apparatus for orientating an aerosol or mist forming means of the nebulizer into a substantially vertical position relative to the ground level under force of gravity. Particularly, there is provided a nebulizer orientation apparatus comprising first and second straight hollow bodies in flow communication with each other via a joint means, which joint means facilitating movement of the first and second straight hollow bodies relative to each other in a first plane facilitated by the joint means, and wherein the first straight hollow body is weighted relative to the second straight hollow body to facilitate displacement of the first body under force of gravity relative to the second body.

50. 发明申请

US20200282159A1 INHALER PARTICULARLY A CANNABINOID INHALER AND A METHOD OF ASSEMBLING SUCH AN INHALER 审中-公开
公开(公告)号：US20200282159A1
公开(公告)日：2020-09-10
申请号：US16754588
申请日：2018-10-04
申请人： SENZER LIMITED
发明人： Alex HEARN , Paul YOUNG , Guillaume PARRIN
IPC分类号： A61M15/00 , A61M15/06 , A61M11/02
摘要： An inhaler comprising an inner housing (1) with a pressurised reservoir of an inhalable composition. A breath operated valve (5) is operable by a user inhaling on an inhaling end of the inhaler. A composition flow path extends from the breath operated valve (5) to the inhaling end via which the composition is dispensed when the breath operated valve is opened. The breath operated valve (5) is biased closed by a biasing member contacting the breath operated valve at one end. A bung (16) in the inner housing is positioned in an opening in the inner housing to support the end of the biasing member (8) opposite to the breath operated valve. A rigid outer housing (3) surrounds the inner housing and supports the bung (16).

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