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    • 45. 发明授权
    • Process and system for reducing sizes of emulsion droplets and emulsions having reduced droplet sizes
    • 降低液滴尺寸的乳液液滴和乳液尺寸的方法和系统
    • US09000053B2
    • 2015-04-07
    • US12997996
    • 2009-06-17
    • Thomas G. MasonMichael M. Fryd
    • Thomas G. MasonMichael M. Fryd
    • A01N25/00A61K47/00B01F3/22B01F3/08
    • B01F3/0811B01F3/088B01F3/22B01F3/2246
    • A method of producing an emulsion includes preparing a droplet solution comprising first and second molecular species, the droplet solution being in a fluid phase, wherein the first molecular species is soluble in the second molecular species; forming a plurality of droplets from the droplet solution in a bulk fluid to create a first emulsion, the plurality of droplets having a first ensemble average radius in the bulk fluid, wherein the first molecular species of the droplet solution is at least partially soluble in the bulk fluid and the droplet solution is at least partially immiscible in the bulk fluid; and allowing molecules of the first molecular species to migrate from the plurality of fluid droplets to the bulk fluid due to a higher concentration of the first molecular species in the droplet solution than the bulk fluid to result in the plurality of droplets having a second ensemble average radius that is smaller than the first ensemble average radius. An emulsion includes a bulk fluid and a plurality of droplets dispersed in the bulk fluid. The plurality of droplets have an ensemble average radius less than about 25 nm and greater than about 5 nm.
    • 制备乳液的方法包括制备包含第一和第二分子种类的液滴溶液,液滴溶液在流体相中,其中第一分子物质可溶于第二分子物质; 在大量流体中从液滴溶液形成多个液滴以产生第一乳液,所述多个液滴在本体流体中具有第一整体平均半径,其中液滴溶液的第一分子种类至少部分可溶于 散装流体和液滴溶液在本体流体中至少部分地不混溶; 并且由于液滴溶液中的第一分子物质的浓度比大体积流体高,从而允许第一分子物质的分子从多个流体液滴迁移到大量流体,导致多个液滴具有第二整体平均值 小于第一整体平均半径的半径。 乳液包括散装流体和分散在本体流体中的多个液滴。 多个液滴具有小于约25nm且大于约5nm的整体平均半径。