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41. 发明授权

US07800070B2 Quantum photodetectors, imaging apparatus and systems, and related methods 有权
标题翻译：量子光电检测器，成像设备和系统及相关方法
公开(公告)号：US07800070B2
公开(公告)日：2010-09-21
申请号：US11783613
申请日：2007-04-10
申请人： Irving Weinberg , Valeri Saveliev
发明人： Irving Weinberg , Valeri Saveliev
IPC分类号： G01T1/164 , G01T1/24
CPC分类号： G01T1/1615 , A61B6/037 , A61B6/12 , A61B6/4028 , A61B6/4488 , A61B6/541 , G01T1/1617 , G01T1/1644 , G01T1/2008
摘要： A camera sub-module is provided for providing tomographic imaging of radiation emissions generated internally by a body. The camera sub-module includes a radiation-emitting layer having a radioactive source for emitting transmission emissions, and at least one radiation-detection layer for contemporaneously detecting and permitting differentiation between the transmission emissions and emissions generated internal to an imaged body administered with a positron-emitting radiotracer. Also provided herein are imaging systems, scanners, and other apparatus and methods.
摘要翻译：提供了一种相机子模块，用于提供由身体内部产生的辐射辐射的层析成像。照相机子模块包括具有用于发射透射发射的放射源的辐射发射层，以及用于同时检测和允许传播发射与被投射正电子的成像体内部产生的发射之间的差异的至少一个放射线检测层 - 放射性示踪器。本文还提供了成像系统，扫描仪和其他装置和方法。

42. 发明申请

US20100166285A1 SYSTEM AND METHOD FOR ACQUIRING IMAGE DATA 审中-公开
标题翻译：用于获取图像数据的系统和方法
公开(公告)号：US20100166285A1
公开(公告)日：2010-07-01
申请号：US12377145
申请日：2007-08-07
申请人： Jens-Peter Schlomka , Axel Thran
发明人： Jens-Peter Schlomka , Axel Thran
IPC分类号： G06K9/00
CPC分类号： G01V5/0025 , G01T1/1644 , G01V5/005
摘要： According to an exemplary embodiment an imaging system (100) for examining an object under examination comprises a scanning unit, wherein the scanning unit comprises a radiation source (106, 108), and a detection unit (107, 109), wherein the scanning unit is adapted to emit a radiation beam (123), which radiation beam follows a linear movement of the object under examination such that a predetermined region of the object under examination is scanned while the object under examination moves.
摘要翻译：根据示例性实施例，用于检查被检查物体的成像系统（100）包括扫描单元，其中所述扫描单元包括辐射源（106,108）和检测单元（107,109），其中所述扫描单元适于发射辐射束（123），该辐射束遵循检查对象的线性运动，使得被检查对象的被检查物体的预定区域被扫描，同时被检查物体移动。

43. 发明申请

US20100127179A1 NUCLEAR MEDICAL DIAGNOSTIC DEVICE 有权
标题翻译：核医学诊断装置
公开(公告)号：US20100127179A1
公开(公告)日：2010-05-27
申请号：US12376488
申请日：2006-09-19
申请人： Hiromichi Tonami , Junichi Ohi
发明人： Hiromichi Tonami , Junichi Ohi
IPC分类号： G01T1/166 , G01T1/20
CPC分类号： G01T1/1644 , G01T1/1648
摘要： Parameters T1, T2, and K required by a scintillator array identification mechanism in a two-stage scintillator γ-ray detector (depth of interaction (DOI)) are accurately and easily determined. The parameters required by the scintillator array identification mechanism are determined with reference to a first signal count ratio, which is obtained by irradiating a γ-ray on each scintillator array with luminescence pulses in an incident depth direction of the γ-ray having different attenuation time during an inspection stage of the γ-ray detector single unit. Furthermore, a second signal count ratio is obtained by irradiating the γ-ray on a front surface of the γ-ray detector single unit, and then a third signal count ratio is obtained by irradiating the γ-ray on the front surface after the γ-ray detector single unit is installed in a PET device.
摘要翻译：在两级闪烁体γ射线检测器（相互作用深度（DOI））中的闪烁体阵列识别机构所需的参数T1，T2和K被精确且容易地确定。闪烁体阵列识别机构所要求的参数参照第一信号计数比来确定，该第一信号计数比通过在具有不同衰减时间的γ射线的入射深度方向上照射每个闪烁体阵列上的γ射线在γ射线检测器单元的检查阶段。此外，通过在γ射线检测器单元的前表面上照射γ射线获得第二信号计数比，然后通过在γ射线之后照射前表面上的γ射线获得第三信号计数比射线检测器单元安装在PET装置中。

44. 发明申请

US20100074396A1 MEDICAL IMAGING WITH BLACK SILICON PHOTODETECTOR 审中-公开
标题翻译：用黑色硅胶片进行医学成像
公开(公告)号：US20100074396A1
公开(公告)日：2010-03-25
申请号：US12498101
申请日：2009-07-06
申请人： Matthias J. Schmand , Debora Henseler , Ronald Grazioso , Nan Zhang , Mark S. Andreaco
发明人： Matthias J. Schmand , Debora Henseler , Ronald Grazioso , Nan Zhang , Mark S. Andreaco
IPC分类号： A61B6/03 , G01T1/24 , G01T1/20
CPC分类号： G01T1/1644 , A61B6/032 , A61B6/037
摘要： Medical imaging may be accomplished with a high photoconductive gain at a relatively low operating voltage by employing a black silicon photodetector and integrating CMOS components with elements of the photodetector.
摘要翻译：通过采用黑硅光电检测器并将CMOS部件与光电检测器的元件集成，可以在相对低的工作电压下以高的光电导增益实现医学成像。

45. 发明授权

US07667205B2 Method for determining a particle and sensor device therefor 失效
标题翻译：确定颗粒的方法及其传感器装置
公开(公告)号：US07667205B2
公开(公告)日：2010-02-23
申请号：US12089341
申请日：2005-10-05
申请人： Rafael Ballabriga , Michael Campbell , Christer Frojdh , Henricus M. Heijne , Xavier Llopart , Hans-Erik Nilsson , Lukas Tlustos
发明人： Rafael Ballabriga , Michael Campbell , Christer Frojdh , Henricus M. Heijne , Xavier Llopart , Hans-Erik Nilsson , Lukas Tlustos
IPC分类号： H01L27/142 , G01T1/29
CPC分类号： G01T1/17 , G01T1/1644
摘要： A method for determining a particle impact on a sensor device comprising M sensing areas, each impact causing a variation of at least one physical magnitude of several sensing portions, said method comprising the steps of: determining an impact center sensing area, where the variation of the at least one physical magnitude is substantially maximal, allocating a result of a sum of the physical magnitude variations of a first set of N sensing areas, said set including the impact center area and other sensing areas neighboring said impact center sensing area, where N is at least 2 and is strict less than M.
摘要翻译：一种用于确定对包括M个感测区域的传感器设备的颗粒影响的方法，每个影响导致几个感测部分的至少一个物理量值的变化，所述方法包括以下步骤：确定影响中心感测区域，其中，所述至少一个物理量值基本上是最大的，分配第一组N个感测区域的物理幅度变化之和的结果，所述第一组N个感测区域包括冲击中心区域和与冲击中心感测区域相邻的其它感测区域，其中N 至少为2，严格小于M.

46. 发明申请

US20100038546A1 CRYSTAL IDENTIFICATION FOR HIGH RESOLUTION NUCLEAR IMAGING 有权
标题翻译：用于高分辨率核成像的晶体鉴定
公开(公告)号：US20100038546A1
公开(公告)日：2010-02-18
申请号：US12535730
申请日：2009-08-05
申请人： Volkmar SCHULZ
发明人： Volkmar SCHULZ
IPC分类号： G01T1/20
CPC分类号： G01T1/1644 , Y10T29/49826
摘要： A detector for a nuclear imaging system includes a scintillator including an array of scintillator elements and a light guide including a grid which defines light guide elements. Light from scintillations in the scintillation crystal in response to received radiation, passes through the light guide and strikes light sensitive elements of a light sensitive element array. The light sensitive element array includes larger elements in an array in the center surrounded by smaller light sensitive elements located in a peripheral array around the central array.
摘要翻译：用于核成像系统的检测器包括闪烁体，其包括闪烁体元件阵列和包括限定光导元件的格栅的光导。响应于接收到的辐射，闪烁晶体中的闪烁的光通过光导并撞击光敏元件阵列的光敏元件。光敏元件阵列包括位于围绕中心阵列的外围阵列中的较小的光敏元件围绕的阵列中较大的元件。

47. 发明申请

US20100034734A1 SYSTEM AND METHOD FOR QUANTITATIVE MOLECULAR BREAST IMAGING 有权
标题翻译：定量分子乳腺成像的系统和方法
公开(公告)号：US20100034734A1
公开(公告)日：2010-02-11
申请号：US12515369
申请日：2007-12-10
申请人： Michael K. O'Connor , Carrie B. Hruska
发明人： Michael K. O'Connor , Carrie B. Hruska
IPC分类号： A61K51/00
CPC分类号： G01T1/1644 , A61B6/4258
摘要： A system and method for performing quantitative lesion analysis in molecular breast imaging (MBI) using the opposing images of a slightly compressed breast that are obtained from the dual-head gamma camera. The method uses the shape of the pixel intensity profiles through each tumor to determine tumor diameter. Also, the method uses a thickness of the compressed breast and the attenuation of gamma rays in soft tissue to determine the depth of the tumor from the collimator face of the detector head. Further still, the method uses the measured tumor diameter and measurements of counts in the tumor and background breast region to determine relative radiotracer uptake or tumor-to-background ratio (T/B ratio).
摘要翻译：使用从双头伽马照相机获得的略微压缩的乳房的相对图像，在分子乳腺成像（MBI）中进行定量病变分析的系统和方法。该方法使用通过每个肿瘤的像素强度分布的形状来确定肿瘤直径。此外，该方法使用压缩乳房的厚度和软组织中的γ射线的衰减来确定来自检测器头的准直仪面的肿瘤的深度。此外，该方法使用测量的肿瘤直径和肿瘤和背景乳腺区域中的计数测量来确定相对放射性示踪剂摄取或肿瘤与背景比（T / B比）。

48. 发明授权

US07660381B2 Scatter compensation in an X-ray system 失效
标题翻译：在X射线系统中的散射补偿
公开(公告)号：US07660381B2
公开(公告)日：2010-02-09
申请号：US11719555
申请日：2005-11-17
申请人： Johannes Henricus Maria Joosten , Miels Noordhoek , Herman Stegehuis
发明人： Johannes Henricus Maria Joosten , Miels Noordhoek , Herman Stegehuis
IPC分类号： A61B6/00
CPC分类号： G01T1/1644 , A61B6/06 , A61B6/5282 , A61B6/542 , A61B6/544 , Y10S378/901
摘要： Scatter compensation is achieved in an X-ray imaging system by providing collimation means in the form of shutters (12) to collimate the primary X-ray beam (1) such that the radiation (8) transmitted through a subject (4) to be imaged is incident substantially centrally on the active part (14) of an image detector (3), so as to define an active border (14b), in respect of which scatter levels can be measured. An electrical signal (104) representative of the scatter level is subtracted from the electrical signal (7) representative of the radiation (8) transmitted through the subject, to obtain a scatter-compensated image signal (106).
摘要翻译：通过提供以快门（12）的形式的准直装置来准直主X射线束（1），使得通过被摄物体（4）传播的辐射（8）成为X射线成像系统，实现散射补偿成像的图像基本上集中在图像检测器（3）的有源部分（14）上，以便限定可以测量散射水平的活动边界（14b）。从代表通过被摄体发射的辐射（8）的电信号（7）中减去代表散射电平的电信号（104），以获得散射补偿图像信号（106）。

49. 发明授权

US07643607B2 CT detector array having non-pixelated scintillator array 有权
标题翻译：具有非象素化闪烁体阵列的CT检测器阵列
公开(公告)号：US07643607B2
公开(公告)日：2010-01-05
申请号：US11380488
申请日：2006-04-27
申请人： Haochuan Jiang , David M. Hoffman , James S. Vartuli
发明人： Haochuan Jiang , David M. Hoffman , James S. Vartuli
IPC分类号： H05G1/64 , G01T1/202
CPC分类号： G01T1/2985 , A61B6/032 , A61B6/4233 , G01N23/046 , G01N2223/419 , G01T1/1644 , G01T1/201 , G21K1/02
摘要： The present invention is a directed to a non-pixelated scintillator array for a CT detector as well as an apparatus and method of manufacturing same. The scintillator array is comprised of a number of ceramic fibers or single crystal fibers that are aligned in parallel with respect to one another. As a result, the pack has very high dose efficiency. Furthermore, each fiber is designed to direct light out to a photodiode with very low scattering loss. The fiber size (cross-sectional diameter) may be controlled such that smaller fibers may be fabricated for higher resolution applications. Moreover, because the fiber size can be controlled to be consistent throughout the scintillator array and the fibers are aligned in parallel with one another, the scintillator array, as a whole, also is uniform. Therefore, precise alignment with the photodiode array or the collimator assembly is not necessary.
摘要翻译：本发明涉及一种用于CT检测器的非像素化闪烁体阵列以及其制造方法。闪烁体阵列包括相对于彼此平行对准的多个陶瓷纤维或单晶纤维。因此，该包装具有非常高的剂量效率。此外，每个光纤被设计成将光引导到具有非常低的散射损耗的光电二极管。可以控制纤维尺寸（横截面直径），使得可以制造更小的纤维用于更高分辨率的应用。此外，由于可以将整个闪烁体阵列的纤维尺寸控制为一致，并且纤维彼此平行排列，所以闪烁体阵列整体上也是均匀的。因此，不需要与光电二极管阵列或准直器组件的精确对准。

50. 发明授权

US07633057B2 PMT gain and energy calibrations using lutetium background radiation 失效
标题翻译：使用镥背景辐射的PMT增益和能量校准
公开(公告)号：US07633057B2
公开(公告)日：2009-12-15
申请号：US12088087
申请日：2006-09-15
申请人： Steven Cooke , Thomas Laurence
发明人： Steven Cooke , Thomas Laurence
IPC分类号： G01T1/20
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1644 , G01T1/202
摘要： A scintillator (18) includes radioactive elements which emit radiation of a characteristic energy, such as lutetium176, which emits 202 keV and 307 keV γ-rays. The scintillators have light output levels that vary and photomultiplier tubes that respond to the light scintillations tend to drift. When a scanner (10) is not generating diagnostic images, the photomultiplier tubes detect scintillations from the lutetium 176 radiation. A self-calibration processor (40) adjusts the gain for each photomultiplier tube such that its output peak corresponds to 202 keV or 307 keV and adjusts a scaling factor for PMT outputs corresponding to each scintillator such that the output peaks have a common amplitude.
摘要翻译：闪烁体（18）包括发射特征能量的辐射的放射性元素，例如镥176，其发射202keV和307keV伽马射线。闪烁体具有变化的光输出水平，并且响应于光闪烁的光电倍增管倾向于漂移。当扫描器（10）不产生诊断图像时，光电倍增管检测来自镥176辐射的闪烁。自校准处理器（40）调整每个光电倍增管的增益，使得其输出峰值对应于202keV或307keV，并且调整对应于每个闪烁体的PMT输出的缩放因子，使得输出峰值具有共同的幅度。

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