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41. 发明申请

US20150164833A1 NUTRITIONAL COMPOSITION CONTAINING A NEUROLOGIC COMPONENT OF URSOLIC ACID AND USES THEREOF 审中-公开
标题翻译：含有酸性神经元成分的营养成分及其用途
公开(公告)号：US20150164833A1
公开(公告)日：2015-06-18
申请号：US14109435
申请日：2013-12-17
申请人： MEAD JOHNSON NUTRITION COMPANY
发明人： Chenzhong Kuang , Yan Xiao , Dirk Hondmann
IPC分类号： A61K31/19 , A61K31/716 , A61K31/07 , A61K31/59 , A61K31/355 , A61K31/122 , A61K31/51 , A61K31/525 , A61K31/4415 , A61K31/714 , A61K31/455 , A61K31/519 , A61K31/197 , A61K31/4188 , A61K31/375 , A61K31/14 , A61K33/42 , A61K33/06 , A61K33/00 , A61K33/20 , A61K33/18 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K31/202
CPC分类号： A61K31/19 , A23L33/115 , A23L33/12 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/21 , A23L33/40 , A61K31/07 , A61K31/122 , A61K31/14 , A61K31/197 , A61K31/202 , A61K31/355 , A61K31/375 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/59 , A61K31/714 , A61K31/716 , A61K33/00 , A61K33/06 , A61K33/18 , A61K33/20 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/42
摘要： The present disclosure generally relates to nutritional compositions that are suitable for administration to adult and pediatric subjects that include ursolic acid, and advantageously provide beneficial health effects such as enhanced brain development and improved memory, cognition, hand-eye coordination, and enhanced focusing. Furthermore, the ursolic acid may act synergistically with other brain nutrients that may be present in the compositions.
摘要翻译：本公开内容通常涉及适合于包括熊果酸的成人和儿科受试者的营养组合物，并且有利地提供有益的健康效果，例如增强的脑发育和改善的记忆，认知，手眼协调和增强聚焦。此外，熊果酸可以与组合物中可能存在的其它脑营养物协同作用。

42. 发明申请

US20150099011A1 INACTIVATION OF PAPILLOMAVIRUS 审中-公开
标题翻译：斑马鱼灭活
公开(公告)号：US20150099011A1
公开(公告)日：2015-04-09
申请号：US14566956
申请日：2014-12-11
申请人： Jenny Colleen McCloskey
发明人： Jenny Colleen MCCLOSKEY , Richard Alan FOX
IPC分类号： A61K33/18 , A61K9/00 , A61M25/10
CPC分类号： A61K33/18 , A61K9/0031 , A61K9/0034 , A61M25/10 , A61M31/00 , A61M2025/105 , A61M2025/1052 , A61M2202/206 , A61M2210/1067
摘要： A method of treating early papillomavirus infection of an orifice of a human or animal body including any canal associated with an orifice, comprising applying a viral inactivation agent to the orifice and/or canal in an amount effective to inactivate a portion of the virus infecting the orifice or canal. Apparatus is also disclosed.
摘要翻译：一种治疗人或动物体的孔口的早期乳头状瘤病毒感染的方法，包括与孔口相关联的任何运河，包括以有效的方式将病毒灭活剂施用于孔和/或管道，以有效地灭活一部分感染孔或运河。还公开了装置。

43. 发明授权

US08951578B2 Rebound hoof pack 有权
标题翻译：反弹蹄包
公开(公告)号：US08951578B2
公开(公告)日：2015-02-10
申请号：US13317190
申请日：2011-11-16
申请人： Ashley Kehoe
发明人： Ashley Kehoe
IPC分类号： A61K9/00 , A01N59/08 , A61K33/18 , A61K36/28
CPC分类号： A61K33/18 , A61K9/0014 , A61K35/04 , A61K36/28 , A61K36/752 , A61K2300/00
摘要： A compound of all natural ingredients allows for treatment of infected, inflamed, and sore hooves without the need for wrapping the hoof with a diaper or vet wrap as is conventional. The compound is packable into the bottom of a hoof. A sugar base allows the compound to stick to the underside of a hoof and remain applied without the wrap. Epsom salts and iodine provide antiseptic and antimicrobial properties, and pine tar provides moisture balance within the hoof in addition to supplementing the stickiness of the compound. Applied compound may be covered with a piece of paper or cloth.
摘要翻译：所有天然成分的化合物允许治疗感染的，发炎的和酸痛的蹄，而不需要像传统的那样用尿布或兽医包装来包裹蹄。化合物可以包装到蹄的底部。糖基允许化合物粘在蹄的下侧，并保持施加而不用包裹。泻盐和碘提供防腐和抗菌性能，松油焦油除了补充化合物的粘性之外还提供蹄内的水分平衡。应用的复合物可以用一块纸或布覆盖。

44. 发明授权

US08940281B2 Composition using cross-linked hyaluronic acid for topical cosmetic and therapeutic applications 有权
标题翻译：使用交联透明质酸用于局部化妆品和治疗应用的组合物
公开(公告)号：US08940281B2
公开(公告)日：2015-01-27
申请号：US14217869
申请日：2014-03-18
申请人： LuroMed LLC
发明人： Adelya K. Leshchiner , Nancy E. Larsen , Edward G. Parent
IPC分类号： A61K8/00 , A61K8/18 , A61K31/74 , A61K31/56 , A61K38/12 , A61K31/70 , A61K31/34 , A61K31/715 , A61K31/19 , A61K31/16 , A61Q17/04 , A01N43/04 , A01N43/08 , A01N37/00 , A01N37/18 , A61K47/36 , A61K8/04 , A61K8/73 , A61K9/00 , A61K31/00 , A61K31/4015 , A61K31/573 , A61K33/18 , A61K45/06 , A61Q19/00 , A61K8/36 , A61K8/37 , A61K8/60 , A61K8/67 , A61K31/165 , A61K31/79
CPC分类号： A61K8/735 , A61K8/042 , A61K8/345 , A61K8/36 , A61K8/37 , A61K8/42 , A61K8/4973 , A61K8/60 , A61K8/676 , A61K8/97 , A61K9/0014 , A61K9/0046 , A61K9/06 , A61K31/00 , A61K31/165 , A61K31/4015 , A61K31/573 , A61K31/79 , A61K33/18 , A61K38/12 , A61K45/06 , A61K47/36 , A61K2800/10 , A61K2800/28 , A61K2800/524 , A61K2800/592 , A61K2800/74 , A61Q17/04 , A61Q19/00 , A61K2300/00
摘要： Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.
摘要翻译：公开了包含交联透明质酸凝胶，优选乙烯基砜交联的透明质酸，称为hylan B凝胶的组合物，用于局部化妆品和皮肤病学制剂。这些制剂中的hylan B凝胶提供了将掺入的物质延长递送至皮肤表面，在皮肤表面上提供水合膜，并在皮肤上提供实质和相容的膜。

45. 发明申请

US20140348775A1 WOUND TREATMENT DRUG FOR EXTERNAL USE 审中-公开
标题翻译：治疗外用药物外用药物
公开(公告)号：US20140348775A1
公开(公告)日：2014-11-27
申请号：US14455135
申请日：2014-08-08
申请人： Maruishi Pharmaceutical Co., Ltd. , MIE UNIVERSITY
发明人： Hitoshi MIZUTANI , Yoshiaki MIYAMOTO , Atsushi NISHIKAWA
IPC分类号： A61K47/06 , A61K31/79
CPC分类号： A61K47/06 , A61K9/0014 , A61K9/06 , A61K31/79 , A61K33/18
摘要： [Problems] The objective is to provide a new low-toxic drug for external use for intractable diseases, such as erosion, decubitus, and skin ulcer, that prevents cicatrization and reduces iodine accumulation on wound surfaces with sufficiently promoting healing.[Means for solving problem] Preparation of a wound treatment drug for external use containing oily bases and iodine but substantially no white soft sugar, which is a characteristic of the drug of this invention. The invented drug prevents infection through the wound surface due to a sufficient bactericidal effect of iodine, and promotes wound healing, prevents cicatrization and reduces iodine accumulation on the wound surface by maintenance of appropriate moisture in the wound surface due to a moisturizing effect of oily bases.
摘要翻译： [问题]目的是提供一种新的低毒药物，用于难治性疾病，如侵蚀，褥疮和皮肤溃疡，可以预防瘢痕形成，减少伤口表面的碘积累，充分促进愈合。 [解决问题的方法]作为本发明的药物的特征的含有油性基质和碘但基本上不含白色软糖的外用伤口治疗药物的制备。本发明的药物由于碘的足够的杀菌作用而防止了伤口表面的感染，并且由于油性基质的保湿效果，通过维持伤口表面的适当水分，促进伤口愈合，防止伤口愈合并减少伤口表面的碘积聚。

46. 发明申请

US20140308331A1 INTERPOLYMER NETWORK DELIVERY SYSTEM 有权
标题翻译：内部网络交付系统
公开(公告)号：US20140308331A1
公开(公告)日：2014-10-16
申请号：US14238605
申请日：2012-08-12
申请人： Joachim B. Kohn , Carmine P. Iovine , Niraj Ramachandran
发明人： Joachim B. Kohn , Carmine P. Iovine , Niraj Ramachandran
IPC分类号： A61K47/36 , A61L31/16 , C08G18/83 , A61K45/06 , A61L31/04 , A61K47/32 , A61K9/70 , A61K33/18
CPC分类号： A61K47/36 , A61K9/7023 , A61K33/18 , A61K45/06 , A61K47/32 , A61L31/042 , A61L31/048 , A61L31/16 , C08G18/831
摘要： This invention relates to compositions and applications for an interpolymer network delivery system containing iodine.
摘要翻译：本发明涉及含有碘的互聚物网络递送系统的组合物和应用。

47. 发明授权

US08840950B2 Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore 有权
标题翻译：营养补充营养缺乏的组成和使用方法
公开(公告)号：US08840950B2
公开(公告)日：2014-09-23
申请号：US13105383
申请日：2011-05-11
申请人： Jacqueline M. Hibbert , Jonathan K. Stiles , Kayellen Umeakunne , Hyacinth I. Hyacinth
发明人： Jacqueline M. Hibbert , Jonathan K. Stiles , Kayellen Umeakunne , Hyacinth I. Hyacinth
IPC分类号： A23L1/29
CPC分类号： A61K33/32 , A23L33/105 , A23L33/115 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/17 , A23L33/175 , A23L33/30 , A23V2002/00 , A61K31/015 , A61K31/07 , A61K31/198 , A61K31/355 , A61K31/375 , A61K31/4172 , A61K31/455 , A61K31/51 , A61K31/525 , A61K31/59 , A61K31/675 , A61K31/7004 , A61K31/714 , A61K33/00 , A61K33/06 , A61K33/18 , A61K33/24 , A61K33/26 , A61K33/30 , A61K36/88
摘要： A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.
摘要翻译：公开了用于治疗受试者的医疗状况引起的营养缺陷的营养补充剂组合物。本申请还公开了一种使用营养补充剂组合物治疗患有由镰状细胞性贫血引起的并发症的受试者的方法。该方法包括向受试者施用有效量的营养补充剂。

48. 发明申请

US20140193371A1 Method for the Prevention and Treatment of Cancer, Tuberculosis and Related Diseases 审中-公开
标题翻译：预防和治疗癌症，结核病及相关疾病的方法
公开(公告)号：US20140193371A1
公开(公告)日：2014-07-10
申请号：US14149180
申请日：2014-01-07
申请人： Harold Edward Siess
发明人： Harold Edward Siess
IPC分类号： A61K35/76 , A61K35/74 , A61K33/36 , A61K33/18 , A61K31/075 , A61K33/00
CPC分类号： A61K33/18 , A23L1/293 , A61K31/00 , A61K33/24 , A61K33/34 , A61K33/36 , A61K33/38 , A61K35/74 , A61K35/76 , A61K38/164 , A61K45/06
摘要： A method for preventing and treating one or more disease states including the steps of altering the diet of an individual and then administering a drug to the individual. Plasma vitamin C level is reduced from a first level to a second level that is lower than the first level, such that a pharmacological response of the body of the individual to a drug at the first level is different from the pharmacological response of the body of said individual to the drug at the second level.
摘要翻译：一种预防和治疗一种或多种疾病状态的方法，包括以下步骤：改变个体的饮食，然后向个体施用药物。血浆维生素C水平从第一水平降低到低于第一水平的第二水平，使得个体身体对第一水平的药物的药理学反应不同于身体的药理反应个人对二级药物说。

49. 发明申请

US20140158057A1 Automated Method and System for Introducing Molecular Iodine into Drinking Water 审中-公开
标题翻译：将分子碘引入饮用水的自动化方法和系统
公开(公告)号：US20140158057A1
公开(公告)日：2014-06-12
申请号：US13916681
申请日：2013-06-13
申请人： James C. Richards
发明人： James C. Richards
IPC分类号： A01K7/02 , A61K33/18
CPC分类号： A01K7/02 , A01K7/06 , A01N59/12 , A61K8/20 , A61K33/18 , A61Q11/00 , C02F1/003 , C02F1/008 , C02F1/283 , C02F1/686 , C02F1/766 , C02F2001/427 , C02F2103/026 , C02F2103/20 , C02F2303/185 , C02F2307/10
摘要： A system for delivering molecular iodine or other substance into a pet's drinking water on a daily basis without exceeding the safe amount allowed for the pet. The system delivers a particular amount of molecular iodine into the pet water supply to achieve maximum benefit of I2 to reduce or eliminate bad pet breath and minimize total iodine in the pet diet so that 20-40 μg/mL/Kg/day iodine is consumed for optimum thyroid health. The preferred method is to use a solution created by dissolving iodine crystals in absolute ethanol. The iodine will only be in solution as I2 for a short time as it undergoes out gassing and hydrolysis at neutral pH. The present invention removes the iodine from the drinking water after the pet drinks. Therefore, during the day, pets will get no additional iodine—only fresh water. Each enrolled pet is electronically recognized by the system.
摘要翻译：每天将分子碘或其他物质分配到宠物饮用水中的系统，不超过宠物允许的安全量。该系统将特定量的分子碘输送到宠物饮水中以实现I2的最大益处，以减少或消除宠物饮食中的不良宠物呼吸并使总碘最小化，从而消耗20-40μg/ mL / Kg /天的碘为了最佳的甲状腺健康。优选的方法是使用通过将碘晶体溶解在无水乙醇中产生的溶液。由于碘在中性pH下经历放气和水解，所以碘将仅在I2溶液中短时间存在。本发明在宠物饮料之后从饮用水中除去碘。因此，白天，宠物不会得到额外的纯碘淡水。每个注册宠物由系统电子认可。

50. 发明授权

US08637554B2 Methods for treating thyroid cancer 有权
标题翻译：治疗甲状腺癌的方法
公开(公告)号：US08637554B2
公开(公告)日：2014-01-28
申请号：US12436957
申请日：2009-05-07
申请人： Marcia S. Brose
发明人： Marcia S. Brose
IPC分类号： A61K31/44 , A61K31/17
CPC分类号： A61K51/02 , A61K31/44 , A61K31/4436 , A61K33/18 , A61K45/06 , G01N2800/52 , A61K2300/00
摘要： The invention provides methods for enhancing iodine absorption in a thyroid in a subject and treating thyroid cancer by administering to the subject a composition which includes a multi-kinase inhibitor. Furthermore, the invention provides methods for improving a medical diagnostic procedure based on radioactive iodine in a subject by administering to the subject a composition comprising a multi-kinase inhibitor.
摘要翻译：本发明提供了通过向受试者施用包含多激酶抑制剂的组合物来增强受试者甲状腺中的碘吸收并治疗甲状腺癌的方法。此外，本发明提供了通过向受试者施用包含多激酶抑制剂的组合物来改善受试者中基于放射性碘的医学诊断程序的方法。

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