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41. 发明授权

US09034034B2 Devices for reducing left atrial pressure, and methods of making and using same 有权
标题翻译：降低左心房压力的装置，以及制造和使用方法
公开(公告)号：US09034034B2
公开(公告)日：2015-05-19
申请号：US13193335
申请日：2011-07-28
申请人： Yaacov Nitzan , Menashe Yacoby
发明人： Yaacov Nitzan , Menashe Yacoby
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2412 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61F2/2415 , A61F2/2418 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/001 , A61F2230/005 , A61F2230/0078
摘要： A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.
摘要翻译：用于调节患者左心房和右心房之间的血压的装置包括沙漏形支架，其包括颈部区域和第一和第二扩张末端区域，所述颈部区域设置在第一和第二端部区域之间，并且被配置为接合卵圆窝的患者房间隔; 以及单向组织瓣膜，其联接到所述第一扩张末端区域并且构造成当左心房中的血压超过右心房中的血压时将血液从左心房分流到右心房。本发明的装置可以减少左心房压力和左心室舒张末期压力，并且可以增加心输出量，增加射血分数，缓解肺充血以及降低肺动脉压力等益处。本发明的装置可以用于例如治疗具有心力衰竭，肺充血或心肌梗死的受试者以及其它病症。

42. 发明授权

US09023074B2 Multi-stage occlusion devices 有权
标题翻译：多级闭塞装置
公开(公告)号：US09023074B2
公开(公告)日：2015-05-05
申请号：US13461260
申请日：2012-05-01
申请人： Elizabeth Theobald , James R. Randolph , Dusan Pavcnik , Frederick Keller , Brad Shirley , Sean Chambers , Ram Paul , Rodney Thurman , Michael Deckard
发明人： Elizabeth Theobald , James R. Randolph , Dusan Pavcnik , Frederick Keller , Brad Shirley , Sean Chambers , Ram Paul , Rodney Thurman , Michael Deckard
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/1214 , A61B17/0057 , A61B2017/00597
摘要： An occlusion device has a covering attached to a support frame that includes a disc-shaped member and a crossbar that extends across a central opening defined by the disc-shaped member. The occlusion device has a first, or deployed, configuration in which the crossbar defines a curve that extends from the disc-shaped member, and a second, or resting, configuration in which the disc-shaped member and the crossbar lie substantially in a single plane. Each of the disc-shaped member and the crossbar include a core wire that extends through a lumen of a coil multiple times.
摘要翻译：闭塞装置具有附接到支撑框架的覆盖物，该支撑框架包括圆盘状构件和跨越由盘状构件限定的中心开口延伸的横杆。闭塞装置具有第一或部署的构造，其中横杆限定从盘形构件延伸的曲线，以及第二或静止构造，其中盘形构件和横杆基本上位于单个飞机圆盘状构件和横杆中的每一个都包括多次延伸通过线圈的内腔的芯线。

43. 发明申请

US20150119929A1 VASCULATURE CLOSURE METHODS 审中-公开
标题翻译：血管闭塞方法
公开(公告)号：US20150119929A1
公开(公告)日：2015-04-30
申请号：US14499911
申请日：2014-09-29
申请人： E-Pacing, Inc.
发明人： Abraham Penner , Lone Wolinsky , Alon Ben-Yosef
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0625 , A61B2017/00004 , A61B2017/00592 , A61B2017/00597 , A61B2017/0061 , A61B2017/00615 , A61B2017/00623 , A61B2017/00628 , A61B2017/00659 , A61B2017/00867
摘要： Vasculature closure devices, and systems and methods for their use, are provided. In one embodiment, the method includes deploying a vasculature closure device including a support frame and a sealing membrane into a vessel through a puncture site, wherein the support frame is in a collapsed configuration during deployment, and expanding the support frame into an expanded configuration within the vessel such that the sealing membrane is pushed against the puncture site.
摘要翻译：提供脉管系统闭合装置，以及其使用的系统和方法。在一个实施例中，该方法包括通过穿刺部位将包括支撑框架和密封膜的脉管系统闭合装置部署到容器中，其中支撑框架在展开期间处于折叠构造，并且将支撑框架扩展为扩展构型该容器使得密封膜被推靠在穿刺部位上。

44. 发明授权

US09005240B2 Device, kit and method for closure of a body lumen puncture 有权
标题翻译：用于闭合体腔穿刺的装置，试剂盒和方法
公开(公告)号：US09005240B2
公开(公告)日：2015-04-14
申请号：US13394802
申请日：2010-09-07
申请人： Anders Jönsson
发明人： Anders Jönsson
IPC分类号： A61B17/08 , A61D1/00 , A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00579 , A61B2017/00597 , A61B2017/00637 , A61B2017/00659 , A61B2017/00889 , A61B2017/00893
摘要： A medical device and method for closure of a puncture in a body lumen are disclosed. The device has an aggregate (10) of a support structure (20) and a substantially fluid tight patch member (30) attached thereto at an attachment unit (40). The aggregate has a first, temporary delivery shape, for delivery to an interior of said body lumen and to be subsequently subjected to a change of shape to a second shape, which is a tubular shape. When delivered in said body lumen, the patch member is arranged radially outside of said tubular support structure and arranged towards an inner tissue wall of the body lumen. The aggregate is the detached from a delivery device and said puncture is intraluminally closed in a leakage tight manner, advantageously supported by a physiological pressure of a body fluid in said body lumen. The device may biodegrade over time.
摘要翻译：公开了一种用于封闭体腔中的穿刺的医疗装置和方法。该装置具有支撑结构（20）的集合体（10）和在附接单元（40））附接到其上的基本上流体密封的贴片构件（30）。聚集体具有第一临时输送形状，用于输送到所述体腔的内部，并随后经受形状变化为管状形状的第二形状。当递送在所述体腔中时，补片部件设置在所述管状支撑结构的径向外侧并且朝向体腔的内部组织壁布置。聚集体是从输送装置分离出来的，并且所述穿刺以泄漏密封的方式内腔闭合，有利地由所述体腔内的体液的生理压力支撑。该设备可能随时间生物降解。

45. 发明授权

US08915958B2 Devices for transcatheter prosthetic heart valve implantation and access closure 有权
标题翻译：经导管假体心脏瓣膜植入和通路闭合的装置
公开(公告)号：US08915958B2
公开(公告)日：2014-12-23
申请号：US13720176
申请日：2012-12-19
申请人： St. Jude Medical, Inc.
发明人： Peter Nicholas Braido
IPC分类号： A61F2/24 , A61B17/32 , A61B17/00 , A61B17/3205
CPC分类号： A61F2/2403 , A61B17/0057 , A61B17/32 , A61B17/32053 , A61B2017/00247 , A61B2017/00349 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61B2017/320064 , A61F2/2436
摘要： Apparatus for use in conjunction with implanting a collapsible and re-expandable prosthetic heart valve in a patient by means that are less invasive than traditional open-chest, open-heart surgery. The apparatus may include a one-way valve for preventing blood from escaping from the patient's circulatory system when that system is entered to implant the prosthetic heart valve. The apparatus may include various forms of cutters for gaining access to the patient's circulatory system. The apparatus may include various forms of devices for quickly closing the access to the patient's circulatory system after the prosthetic heart valve has been implanted.
摘要翻译：通过与传统的开胸胸腔开放心脏手术相比侵入性较小的手段，与患者一起植入可塌陷和可再膨胀的假体心脏瓣膜的装置。该装置可以包括单向阀，用于当输入系统以植入假体心脏瓣膜时防止血液从患者的循环系统逸出。该装置可以包括用于获得患者循环系统的各种形式的切割器。该装置可以包括各种形式的装置，用于在植入人造心脏瓣膜之后快速关闭对患者循环系统的接近。

46. 发明申请

US20140364899A1 SYSTEMS AND METHODS FOR IMPROVED VESSEL ACCESS CLOSURE 审中-公开
公开(公告)号：US20140364899A1
公开(公告)日：2014-12-11
申请号：US14301889
申请日：2014-06-11
申请人： PROMED, INC.
发明人： Richard GINN , Hans VALENCIA
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B2017/00557 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00623 , A61B2017/00637 , A61B2017/00659 , A61B2017/00663 , A61B2017/0417 , A61B2017/0496 , A61F2/2427 , A61F2/82 , A61F2/89 , A61F2002/075 , A61F2002/828
摘要： Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.

47. 发明授权

US08870947B2 Medical device fixation anchors 有权
标题翻译：医疗器械固定锚
公开(公告)号：US08870947B2
公开(公告)日：2014-10-28
申请号：US13615325
申请日：2012-09-13
申请人： Edward E. Shaw
发明人： Edward E. Shaw
IPC分类号： A61F2/06 , A61B17/12 , A61B17/00 , A61F2/848 , A61F2/86
CPC分类号： A61F2/848 , A61B17/12122 , A61B2017/00243 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00632 , A61B2017/00862 , A61B2017/00867 , A61F2/86 , A61F2002/8483 , A61F2002/8486
摘要： An implantable medical device includes a frame that includes at least one elongate member. The implantable medical device also includes a fixation member that has a first cuff, a second cuff, a tissue engagement member configured to anchor to tissue at an implant site to thereby hold the implantable medical device in a position at the implant site, and a cuff joining member that has an arcuate shape and that is connected at a first end to the first cuff and at a second end to the second cuff. The first cuff substantially surrounds a perimeter of a first portion of the at least one elongate member, the second cuff substantially surrounds a perimeter of a second portion of the at least one elongate member, and the cuff joining member does not substantially surround a perimeter of any portion of the at least one elongate member.
摘要翻译：可植入医疗装置包括一个包括至少一个细长构件的框架。可植入医疗装置还包括固定构件，该固定构件具有第一箍，第二箍和组织接合构件，所述组织接合构件构造成锚定于植入位置处的组织，从而将可植入医疗装置保持在植入部位的位置，连接构件，其具有弓形形状，并且在第一端连接到所述第一袖带，并且在第二端连接到所述第二袖带。所述第一箍基本上围绕所述至少一个细长构件的第一部分的周边，所述第二箍基本上围绕所述至少一个细长构件的第二部分的周边，并且所述箍连接构件基本上不包围所述至少一个细长构件的任何部分。

48. 发明授权

US08870937B2 Method for vessel access closure 有权
标题翻译：船只通行关闭方法
公开(公告)号：US08870937B2
公开(公告)日：2014-10-28
申请号：US12841052
申请日：2010-07-21
申请人： Richard S. Ginn , Nicanor Domingo , Hans F. Valencia , Robert Elliott DeCou , Scott Yerby
发明人： Richard S. Ginn , Nicanor Domingo , Hans F. Valencia , Robert Elliott DeCou , Scott Yerby
IPC分类号： A61F2/06 , A61B17/00 , A61F2/82
CPC分类号： A61B17/0057 , A61B2017/00592 , A61B2017/00597 , A61B2017/0061 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00867 , A61B2017/00942 , A61F2/82 , A61F2/95 , A61F2/954 , A61F2/966 , A61F2002/823 , A61F2002/9534
摘要： Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.
摘要翻译：描述了用于关闭血管进入端口（例如动脉切开术）的实施例，其涉及可扩张装置的放置和展开，所述可扩张装置被配置为防止血流穿过对象动脉切开术，同时将血管内流动紊乱保持最小。合适的假体可以包括由诸如形状记忆合金或聚合物的柔性材料的长度构成的一个或多个框架。这样的框架可以耦合到片状或管状结构，其构造成扩展负载，使可能与血管内流动相关的血栓形成最小化并且保持止血。

49. 发明申请

US20140296909A1 Medical Implant, A Kit And A Method Of Manufacturing A 3D Fabric Of Strands For Forming A Medical Implant 有权
标题翻译：医学植入物，一套工具和一种制造用于形成医疗植入物的三维织物的方法
公开(公告)号：US20140296909A1
公开(公告)日：2014-10-02
申请号：US14354516
申请日：2012-10-26
申请人： Occlutech Holding AG
发明人： Michael Heipl , Sebastian Tilchner , Kathrin Schmidt , Rüdiger Ottma
IPC分类号： A61B17/00 , D03D3/02 , D06B1/00 , D04C3/08
CPC分类号： D04C3/48 , A61B17/0057 , A61B17/12122 , A61B17/12172 , A61B2017/00526 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00606 , D03D3/02 , D04C1/06 , D04C3/08 , D06B1/00 , D10B2509/08
摘要： The disclosure relates to a method of manufacturing a medical implant or structures for a medical implant. Disclosed is an improved occluder (1), which does not damage the surrounding body tissue. In one embodiment, a method of manufacturing a 3D fabric of strands for forming an occluder is provided. The method comprises intertwining the strands along a length of the 3D fabric for forming a primary 3D fabric structure. The intertwining is non-continuous, i.e. the braiding procedure can be halted, for forming a secondary structure of the 3D fabric without intertwining.
摘要翻译：本公开涉及制造用于医疗植入物的医疗植入物或结构的方法。公开了一种改进的闭塞器（1），其不损坏周围的身体组织。在一个实施例中，提供了一种制造用于形成封堵器的股线的3D织物的方法。该方法包括沿三维织物的长度缠绕股线以形成初级3D织物结构。相互缠绕是不连续的，即可以停止编织过程，用于形成3D结构的二次结构而不相互缠绕。

50. 发明授权

US08840641B2 Medical device for modification of left atrial appendage and related systems and methods 有权
标题翻译：用于修改左心耳和相关系统和方法的医疗装置
公开(公告)号：US08840641B2
公开(公告)日：2014-09-23
申请号：US12684795
申请日：2010-01-08
申请人： Scott D. Miles , Daryl R. Edmiston
发明人： Scott D. Miles , Daryl R. Edmiston
IPC分类号： A61B17/00 , A61B17/12 , A61B17/04 , A61B17/122
CPC分类号： A61B17/1215 , A61B17/00234 , A61B17/0057 , A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/12022 , A61B17/12031 , A61B17/1204 , A61B17/12122 , A61B17/12131 , A61B17/12159 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00526 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/0061 , A61B2017/00632 , A61B2017/00867 , A61B2017/00884 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0437 , A61B2017/0446 , A61B2017/0448 , A61B2017/0459 , A61B2017/0464 , A61B2017/1205 , Y10T29/49826
摘要： Medical devices, systems and methods for modifying a left atrial appendage (“LAA”). In one embodiment, a medical device system includes a jailing member or structure positioned over the ostium of an LAA and at least one tissue growth member positioned within the LAA and retained within the LAA by the jailing member. In another embodiment, a medical device includes an atrial stent coupled with a patch that is configured to cover the ostium of an LAA. The patch may have a tissue growth member associated therewith. In another embodiment, the patch may include an open-cell frame which may be used as a jailing member or structure.
摘要翻译：用于修改左心耳（“LAA”）的医疗设备，系统和方法。在一个实施例中，医疗装置系统包括位于LAA的口上方的锁定构件或结构，以及定位在LAA内的至少一个组织生长构件，并且由锁定构件保持在LAA内。在另一个实施例中，医疗装置包括与构造成覆盖LAA的口的贴片配合的心房支架。贴片可以具有与其相关联的组织生长部件。在另一个实施例中，贴片可以包括可用作挂钩构件或结构的开放式框架。

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