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41. 发明申请

US20230043372A1 AN ANTI-MICROBIAL COATING FOR OBJECTS SUCH AS PROSHETIC IMPLANTS 有权
公开(公告)号：US20230043372A1
公开(公告)日：2023-02-09
申请号：US17787786
申请日：2020-12-16
申请人： National University of Ireland, Galway
发明人： Firas Awaja , Giorgio Speranza
IPC分类号： A61L27/30 , A61L27/06 , A61L27/54
摘要： A method of providing an anti-microbial coating on an object, comprises the steps of pretreating the object in a first oxygen plasma to graft oxygen-based functional groups on the surface of the object by plasma enhanced chemical vapour deposition, coating the pretreated object with a suspension of particulate graphene oxide to provide a graphene oxide coating on the object, treating the object in a hydrocarbon plasma to deposit an amorphous hydrocarbon film on the graphene oxide coating by plasma enhanced chemical vapour deposition, and treating the object in a second oxygen plasma configured to etch and flatten the coatings on the surface of the object. A prosthetic implant having a metal or metal alloy surface and an anti-microbial coating on all or part of the surface is also described.

42. 发明授权

US11478248B2 Percutaneous vascular surgical system and method 有权
公开(公告)号：US11478248B2
公开(公告)日：2022-10-25
申请号：US16612643
申请日：2018-05-10
申请人： National University of Ireland Galway
发明人： Sherif Sultan , Niamh Hynes , Robert Miculas , Stefan Lohfeld , Colin Henehan
IPC分类号： A61B17/12 , A61B90/00 , A61B17/00 , A61B17/22
摘要： The present invention provides a percutaneous vascular surgical system for performing endovascular/neurovascular interventions, the system incorporating a sheath having a proximal end and a distal end and defining a main lumen extending between the proximal and distal ends, an auxiliary lumen also defined by the sheath, a reversibly inflatable balloon located about the sheath adjacent the distal end and in fluid communication with the auxiliary lumen, a syringe selectively connectable to the main lumen to create suction through the main lumen, and a vessel closure device for the closure of the arteriotomy, the surgical system and method of the invention having utility in a large number of percutaneous vascular procedures such as carotid artery stenosis or neurovascular interventions and enabling four procedures to be performed with one system, being percutaneous access, emboli removal, flow reversal and arteriotomy closure.

43. 发明授权

US11464564B2 Microwave ablation probe 有权
公开(公告)号：US11464564B2
公开(公告)日：2022-10-11
申请号：US16638058
申请日：2018-06-29
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY
发明人： Jimmy Eaton-Evans , Giuseppe Ruvio , Martin O'Halloran , Jonathan Bouchier-Hayes , Mark Bruzzi
IPC分类号： A61B18/18 , A61B18/00
摘要： A microwave ablation probe (200; 300; 400), comprising: an applicator (202; 302; 402) arranged to apply microwave radiation to heat surrounding tissue; a feeding cable (204; 304; 404) arranged to supply electromagnetic energy to the applicator; a coolant flow path (206) via which coolant is able to flow; and a choke arranged to reduce power reflected from the applicator (202; 302; 402) along the feeding cable (204; 304; 404). The choke comprises a choke member (208; 209; 308; 408) cooled by coolant flowing in the coolant flow path (206). The choke member (208; 209; 308; 408) extends between two points spaced apart in a direction having at least a component parallel to a longitudinal axis of the feeding cable. The choke member (208; 209; 308; 408) comprises one or more turns extending around the longitudinal axis of the feeding cable. The choke member may be a spiral member (208; 308; 408).

44. 发明授权

US11464501B2 Biopsy device 有权
公开(公告)号：US11464501B2
公开(公告)日：2022-10-11
申请号：US16671914
申请日：2019-11-01
申请人： National University of Ireland, Galway
发明人： Damien Long , Edmund Brennan , Eugene Skelton , Anthony Wright
IPC分类号： A61B10/02
摘要： A biopsy device comprising: a cannula comprising an elongate cannula body extending between a cannula distal end and a cannula proximal end to define a lumen, wherein the cannula comprises a cutting portion at the cannula distal end; a stylet comprising an elongate body having a stylet distal end and a stylet proximal end, the stylet being slidably disposed within the lumen, wherein the stylet comprises a tissue sampling portion. The tissue sampling portion is formed by a notch in the body of the stylet at or near the stylet distal end. The biopsy device further comprises an actuator assembly, the actuator assembly arranged to move the cannula relative to the stylet between a retracted position in which at least part of the tissue sampling portion is exposed and an extended position in which the cannula at least partly surrounds the tissue sampling portion. The actuator assembly comprises a cannula actuator moveable between a primed configuration and an actuated configuration to move the cannula between the retracted position and the extended position. The biopsy device further comprises a selective coupling mechanism arranged to provide a selective coupling between the actuator assembly and one or both of the stylet and the cannula.

45. 发明申请

US20220248946A1 A SCOPE 有权
公开(公告)号：US20220248946A1
公开(公告)日：2022-08-11
申请号：US17629224
申请日：2020-07-23
申请人： National University of Ireland, Galway
发明人： Rory O'Callaghan , Ivan Keogh , Martin Gallagher , Elizabeth McGloughlin , Christina Walsh , Martin O'halloran , Jibran Ahmed Abbasi , Barry Mcdermott
IPC分类号： A61B1/227 , A61B1/00 , A61B1/05 , A61B1/06 , A61B1/12
摘要： A scope (1) for examining or surgically treating ears comprising a probe (2); at least one visualiser (3) on the probe having an optical configuration (7), and a light source (42) wherein the visualiser (3) is articulatable about a visualiser articulation axis (3a) by an orienting mechanism (4) for optimal viewing of the ear.

46. 发明授权

US11382599B2 Ultrasound imaging system reconstructing an intravascular image using angular positions of a transducer array 有权
公开(公告)号：US11382599B2
公开(公告)日：2022-07-12
申请号：US17032988
申请日：2020-09-25
申请人： THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH , National University of Ireland, Galway
发明人： Christoph Hennersperger , Andrew Bourke , Fionn Lahart
IPC分类号： A61B8/08 , A61B8/12 , A61B8/00 , A61B18/14 , A61B8/14 , A61B34/10 , A61B18/00 , G06T15/08 , A61B17/00
摘要： A catheter-based ultrasound imaging system configured to provide a full circumferential 360-degree view around an intra-vascular/intra-cardiac imaging-catheter-head by generating a three-dimensional view of the tissue surrounding the imaging-head over time. The ultrasound imaging system can also provide tissue-state mapping capability. The evaluation of the vasculature and tissue characteristics include path and depth of lesions during cardiac-interventions such as ablation. The ultrasound imaging system comprises a catheter with a static or rotating sensor array tip supporting continuous circumferential rotation around its axis, connected to an ultrasound module and respective processing machinery allowing ultrafast imaging and a rotary motor that translates radial movements around a longitudinal catheter axis through a rotary torque transmitting part to rotate the sensor array-tip. This allows the capture and reconstruction of information of the vasculature including tissue structure around the catheter tip for generation of the three-dimensional view over time.

47. 发明申请

US20220054992A1 VORTEX GENERATOR APPARATUS 有权
公开(公告)号：US20220054992A1
公开(公告)日：2022-02-24
申请号：US17416863
申请日：2018-12-21
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY
发明人： Sean MULLIGAN , Eoghan CLIFFORD , Alan CARTY
IPC分类号： B01F5/00 , B01F3/04
摘要： An impeller-free vortex generator apparatus for fluid mixing, including: a fluid tank including: a first fluid inlet port, the first fluid inlet port including a curved flow channel between a first sidewall segment of the fluid tank and a second sidewall segment of the fluid tank, a second fluid inlet port, and a fluid outlet port; and a first fluid intake duct in fluid communication with the first fluid inlet port; wherein the first fluid intake duct is provided substantially on a tangent to the first sidewall segment of the fluid tank and aligned to deliver a first fluid to an internal surface of the first sidewall segment.

48. 发明申请

US20210393746A1 TREATMENT OF MYOCARDIAL INFARCTION 有权
公开(公告)号：US20210393746A1
公开(公告)日：2021-12-23
申请号：US17279129
申请日：2019-09-24
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY , UNIVERSIDAD DE VALLADOLID
发明人： Abhay PANDIT , Paolo CONTESSOTTO , Mark DA COSTA , Jose Carlos RODRIGUEZ-CABELLO
IPC分类号： A61K38/39
摘要： An injectable elastin-like recombinamer (ELR) hydrogel for use in a method of treating a mammal that has suffered a myocardial infarction to modulate the response of cardiac muscle damaged by the infarct is described. The hydrogel is injected into the cardiac muscle damaged by the infarct at least two days after the myocardial infarction, and results in clinically significant repair of cardiac muscle evidenced by at least one or more of reduced scarring, positive remodelling of the damaged muscle, restoring cardiac muscle function to a clinically significant extent after infarction an improvement in angiogenesis, or a decreased pro-inflammatory response in the infarct zone, and typically within 10, 20 or 30 days of administration.

49. 发明申请

US20210361258A1 ULTRASOUND BASED THREE-DIMENSIONAL LESION VERIFICATION WITHIN A VASCULATURE 有权
公开(公告)号：US20210361258A1
公开(公告)日：2021-11-25
申请号：US17041692
申请日：2019-08-30
申请人： THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH , National University of Ireland, Galway
发明人： Christoph Hennersperger , Andrew Bourke , Fionn Lahart
IPC分类号： A61B8/12 , A61B8/08 , A61B8/00 , A61B18/00 , G06T15/08
摘要： A catheter-based ultrasound imaging system configured to provide a full circumferential 360-degree view around an intra-vascular/intra-cardiac imaging-catheter-head by generating a three-dimensional view of the tissue surrounding the imaging-head over time. The ultrasound imaging system can also provide tissue-state mapping capability. The evaluation of the vasculature and tissue characteristics include path and depth of lesions during cardiac-interventions such as ablation. The ultrasound imaging system comprises a catheter with a static or rotating sensor array tip supporting continuous circumferential rotation around its axis, connected to an ultrasound module and respective processing machinery allowing ultrafast imaging and a rotary motor that translates radial movements around a longitudinal catheter axis through a rotary torque transmitting part to rotate the sensor array-tip. This allows the capture and reconstruction of information of the vasculature including tissue structure around the catheter tip for generation of the three-dimensional view over time.

50. 发明申请

US20210307779A1 THROMBECTOMY DEVICES WITH ASPIRATION 有权
公开(公告)号：US20210307779A1
公开(公告)日：2021-10-07
申请号：US17246120
申请日：2021-04-30
申请人： National University of Ireland, Galway
发明人： Mark BRUZZI , Saeid Kasiri Ghahi , Paul Heneghan
IPC分类号： A61B17/3207
摘要： A thrombectomy device includes a handle at a proximal end portion of the device, a cage at a distal end portion of the device, the cage being moveable between an expanded orientation and a contracted orientation, and a first tube extending from the proximal end portion of the device to at least a proximal end portion of the cage. The device also includes a second tube extending from the proximal end portion of the device to at least a distal end portion of the cage, and a self-adjusting control assembly including a biasing element coupled to one of the first tube or the second tube. The biasing element exerts an axial force to urge the cage toward the expanded orientation.

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