专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明授权

US08844350B2 Flow quantity measuring apparatus including branched conductive lines connected to midpoints of series circuits of the bridge circuit 有权
标题翻译：流量测量装置，包括连接到桥式电路的串联电路的中点的分支导线
公开(公告)号：US08844350B2
公开(公告)日：2014-09-30
申请号：US13242130
申请日：2011-09-23
申请人： Junzo Yamaguchi , Yasushi Kohno
发明人： Junzo Yamaguchi , Yasushi Kohno
IPC分类号： G01F1/68 , G01F1/00
CPC分类号： G01F1/00
摘要： A sensor chip in a flow quantity measuring apparatus includes a first conductive line, through which a midpoint electric potential of a first series circuit of a bridge circuit is outputted, is branched from a first midpoint connection on a sensor chip. A second conductive line, through which a midpoint electric potential of a second series circuit of the bridge circuit is outputted, is branched from a second midpoint connection on the sensor chip. The output point of the midpoint electric potential of the first series circuit is provided at a midpoint between two temperature sensor resistors, and the first midpoint connection is provided on a center line of a heater resistor. The output point of the midpoint electric potential of the second series circuit is provided at a midpoint between two temperature sensor resistors, and the second midpoint connection is provided on the center line of the heater resistor.
摘要翻译：流量测量装置中的传感器芯片包括：输出桥电路的第一串联电路的中点电位的第一导线从传感器芯片上的第一中点连接分支。输出桥电路的第二串联电路的中点电位的第二导线从传感器芯片上的第二中点连接分支。第一串联电路的中点电位的输出点设置在两个温度传感器电阻之间的中点处，并且第一中点连接设置在加热电阻器的中心线上。第二串联电路的中点电位的输出点设置在两个温度传感器电阻之间的中点处，第二中点连接设置在加热电阻器的中心线上。

42. 发明授权

US08796247B2 Indole derivative, and pharmacologically acceptable salt thereof 有权
标题翻译：吲哚衍生物及其药理学上可接受的盐
公开(公告)号：US08796247B2
公开(公告)日：2014-08-05
申请号：US13980599
申请日：2012-01-24
申请人： Kazuya Tatani , Atsushi Kondo , Tatsuhiro Kondo , Naohiro Kawamura , Shigeki Seto , Yasushi Kohno
发明人： Kazuya Tatani , Atsushi Kondo , Tatsuhiro Kondo , Naohiro Kawamura , Shigeki Seto , Yasushi Kohno
IPC分类号： C07D209/08 , A61K31/40 , A61K31/4025 , A61K31/443 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D401/06 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , A61K31/404
CPC分类号： C07D209/08 , A61K31/40 , A61K31/4025 , A61K31/404 , A61K31/443 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D401/06 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , A61K2300/00
摘要： The present invention provides a compound represented by the general formula (I) of the present invention, which has EP1 receptor antagonism: wherein A represents a pyridine ring, a furan ring, or the like; Y1 represents a C1-6 alkylene group; Y2 represents a single bond or the like; R1 represents —C(═O)—NH—SO2R6, an acidic 5-membered hetero ring group, or the like; R2 represents an optionally substituted phenyl group, an optionally substituted 5-membered aromatic heterocyclic group, or the like; R3 represents a halogen atom, a C1-6 alkoxy group, or the like; R4 represents a hydrogen atom, a halogen atom, or the like; R5 represents a hydrogen atom or the like; and R6 represents a C1-6 alkyl group or the like], and a pharmaceutically acceptable salt thereof. Furthermore, the compound (I) of the present invention can be used as an agent for treating or preventing LUTS, in particular, various symptoms of OABs.
摘要翻译：本发明提供了具有EP1受体拮抗作用的本发明通式（I）表示的化合物：其中A表示吡啶环，呋喃环等; Y1表示C1-6亚烷基; Y2表示单键等; R 1表示-C（= O）-NH-SO 2 R 6，酸性5元杂环基等; R 2表示任选取代的苯基，任选取代的5元芳族杂环基等; R3表示卤素原子，C1-6烷氧基等; R 4表示氢原子，卤素原子等; R5表示氢原子等; 和R6表示C1-6烷基等〕及其药学上可接受的盐。此外，本发明的化合物（I）可以用作治疗或预防LUTS，特别是OAB的各种症状的药剂。

43. 发明申请

US20130261089A1 DIPHENYL SULFIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT WHICH CONTAINS SAME AS ACTIVE INGREDIENT 有权
标题翻译：含硫酸盐衍生物和药物产品含有活性成分
公开(公告)号：US20130261089A1
公开(公告)日：2013-10-03
申请号：US13883847
申请日：2011-12-20
申请人： Kumi Ishikawa , Shigeru Koga , Yasushi Kohno , Kiyoshi Fujii , Ken Yoshikawa
发明人： Kumi Ishikawa , Shigeru Koga , Yasushi Kohno , Kiyoshi Fujii , Ken Yoshikawa
IPC分类号： C07F9/38
CPC分类号： C07F9/38 , C07F9/091 , C07F9/3808 , C07F9/4006 , C07F9/4015
摘要： [Problem] To provide a diphenyl sulfide derivative which is useful as a pharmaceutical product that has excellent S1P3 antagonist activity.[Solution] The inventors have discovered that a diphenyl sulfide derivative represented by general formula (1) (wherein R1 represents an alkoxy group having 1-6 carbon atoms, R2 represents a propyl group or an allyl group, X represents methylene or an oxygen atom, and Z represents a halogen atom) has excellent S1P3 antagonist activity as a result of extensive researches for the production of a compound that has S1P3 antagonist activity.
摘要翻译： [问题]提供可用作具有优异的S1P3拮抗剂活性的药物的二苯硫醚衍生物。发明人已经发现，通式（1）表示的二苯硫醚衍生物（其中，R1表示碳原子数1〜6的烷氧基，R2表示丙基或烯丙基，X表示亚甲基或氧原子，Z表示卤素原子）作为具有S1P3拮抗剂活性的化合物的生产的广泛研究的结果，具有优异的S1P3拮抗剂活性。

44. 发明申请

US20120079889A1 AIR FLOW QUANTITY MEASURING APPARATUS FOR INTERNAL COMBUSTION ENGINE 有权
标题翻译：用于内燃机的空气流量测量装置
公开(公告)号：US20120079889A1
公开(公告)日：2012-04-05
申请号：US13242349
申请日：2011-09-23
申请人： Yasushi Kohno
发明人： Yasushi Kohno
IPC分类号： G01F1/00
CPC分类号： G01F1/6842 , F02D41/0002 , F02D41/18 , F02D2200/0408 , G01F1/6965 , G01F5/00 , Y02T10/42
摘要： A flow meter outputs a frequency signal, which corresponds to an air flow quantity of intake air to be supplied to an engine. In an engine control unit, when a sensed value of the air flow quantity, which is obtained based on the frequency signal, is within an estimated air flow quantity range, which is estimated based on an operational state of the engine, the sensed value of the air flow quantity is determined as a measurement value of the flow meter. In contrast, when the sensed value of the air flow quantity is out of the estimated air flow quantity range, a median of the estimated air flow quantity range is determined as the measurement value of the flow meter.
摘要翻译：流量计输出对应于供给到发动机的进气的空气流量的频率信号。在发动机控制单元中，当基于频率信号获得的空气流量的感测值在基于发动机的运行状态估计的估计空气流量范围内时，感测值气流量被确定为流量计的测量值。相反，当感测到的空气流量的值在估计的空气流量范围之外时，估计的空气流量范围的中值被确定为流量计的测量值。

45. 发明授权

US08071591B2 7-cycloalkylaminoquinolones as GSK-3 inhibitors 有权
标题翻译： 7-环烷基氨基喹诺酮类作为GSK-3抑制剂
公开(公告)号：US08071591B2
公开(公告)日：2011-12-06
申请号：US12721454
申请日：2010-03-10
申请人： Masahiro Nomura , Kyoko Okada , Taro Sato , Yasushi Kohno
发明人： Masahiro Nomura , Kyoko Okada , Taro Sato , Yasushi Kohno
IPC分类号： C07D498/06 , A61K31/5383
CPC分类号： C07D498/06
摘要： Provided herein are aminoquinolones of formula I and compositions containing the compounds, wherein formula I is The compounds and compositions provided herein are useful in the amelioration or treatment of GSK-3 inhibitors mediated diseases.
摘要翻译：本文提供了式I的氨基喹诺酮和含有化合物的组合物，其中式I是本文提供的化合物和组合物可用于改善或治疗GSK-3抑制剂介导的疾病。

46. 发明申请

US20110178041A1 HETEROCYCLIC BIARYL DERIVATIVE AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT 审中-公开
标题翻译：含有作为活性成分的异源二异氰酸酯衍生物和PDE抑制剂
公开(公告)号：US20110178041A1
公开(公告)日：2011-07-21
申请号：US13121099
申请日：2009-09-24
申请人： Yasushi Kohno , Tatsunobu Sumiya , Satoshi Takita , Akihiko Kojima
发明人： Yasushi Kohno , Tatsunobu Sumiya , Satoshi Takita , Akihiko Kojima
IPC分类号： A61K31/437 , C07D471/04 , C07F5/02 , A61K31/69 , A61P11/00 , A61P19/02 , A61P25/00 , A61P25/28 , A61P25/16 , A61P25/24 , A61P25/18 , A61P3/00 , A61P3/04 , A61P29/00 , A61P11/06 , A61P11/02
CPC分类号： C07D215/26 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04
摘要： Novel heterocyclic biaryl derivatives were disclosed which are useful as pharmaceutical agents and which exhibit a phosphodiesterase-inhibitory action.The heterocyclic biaryl derivatives are represented by the following general formula (1): wherein the Heterocycle 1 and the Heterocycle 2 are directly bonded together.
摘要翻译：公开了可用作药剂并且表现出磷酸二酯酶抑制作用的新型杂环联芳基衍生物。杂环联芳基衍生物由以下通式（1）表示：其中杂环1和杂环2直接键合在一起。

47. 发明申请

US20100234367A1 7-CYCLOALKYLAMINOQUINOLONES AS GSK-3 INHIBITORS 有权
标题翻译：作为GSK-3抑制剂的7-环丙基氨基喹啉
公开(公告)号：US20100234367A1
公开(公告)日：2010-09-16
申请号：US12721454
申请日：2010-03-10
申请人： MASAHIRO NOMURA , Kyoko Okada , Taro Sato , Yasushi Kohno
发明人： MASAHIRO NOMURA , Kyoko Okada , Taro Sato , Yasushi Kohno
IPC分类号： A61K31/5383 , C07D265/34 , A61P3/10 , A61P25/16 , A61P25/28 , A61P25/00 , A61P19/02 , A61P19/10 , A61P1/04 , A61P1/06 , A61P31/04 , A61P35/00
CPC分类号： C07D498/06
摘要： Provided herein are aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases.
摘要翻译：本文提供了式I的氨基喹诺酮和含有该化合物的组合物。本文提供的化合物和组合物可用于预防，改善或治疗GSK-3抑制剂介导的疾病。

48. 发明授权

US07644614B2 Flow quantity measuring device 有权
标题翻译：流量测量装置
公开(公告)号：US07644614B2
公开(公告)日：2010-01-12
申请号：US12108313
申请日：2008-04-23
申请人： Junzo Yamaguchi , Yasushi Kohno
发明人： Junzo Yamaguchi , Yasushi Kohno
IPC分类号： G01F1/68
CPC分类号： G01F1/692
摘要： In a flow quantity measuring device, each of upstream side and downstream side sensing resistors, which are placed on an upstream side and a downstream side, respectively, of a heating resistor, includes resistor elements, each of which forms a folded path. The folded path has a generally constant width along an entire extent thereof and is returned at each of first and second longitudinal end edges of a sensing area. The heating resistor forms a folded path, which has a generally constant width along an entire extent thereof and is returned at the second longitudinal end edge of the heat generating area. First and second ends of the folded path of the heating resistor projects beyond the first longitudinal end edge of the sensing area on a first side of the flow quantity measuring device.
摘要翻译：在流量测量装置中，分别位于加热电阻器的上游侧和下游侧的上游侧和下游侧检测电阻器中的每一个包括各自形成折叠路径的电阻器元件。折叠路径在其整个范围上具有大致恒定的宽度，并且在感测区域的第一和第二纵向端边缘的每一个处返回。加热电阻器形成折叠路径，该折叠路径在其整个范围上具有大致恒定的宽度，并且在发热区域的第二纵向端部边缘处返回。加热电阻器的折叠路径的第一和第二端在流量测量装置的第一侧突出超过感测区域的第一纵向端边缘。

49. 发明授权

US07490436B2 Method of preventing defective germination or growth of plant 失效
公开(公告)号：US07490436B2
公开(公告)日：2009-02-17
申请号：US09837020
申请日：2001-04-18
申请人： Yasushi Kohno , Noritoshi Katsutani
发明人： Yasushi Kohno , Noritoshi Katsutani
IPC分类号： A01C1/06
CPC分类号： A01C1/06 , Y10S47/09 , Y10S47/11
摘要： A method of preventing defective germination or growth of a plant is provided, by which even plant seeds having small size can be sown easily and securely. The method of preventing defective germination or growth of a plant includes the steps of: encapsulating plant seeds in an aqueous gel capsule; refrigerating the plant seeds under the condition that the plant seeds do not germinate; and sowing the plant seeds.

50. 发明申请

US20080207902A1 Pyrazolopyridine-4-Yl Pyridazinone Derivatives and Addition Salts Thereof, and Pde Inhibitors Comprising the Same Derivatives or Salts as Active Ingredient 失效
标题翻译：吡唑并吡啶-4-Y1哒嗪酮衍生物及其加成盐以及包含作为活性成分的相同衍生物或盐的Pde抑制剂
公开(公告)号：US20080207902A1
公开(公告)日：2008-08-28
申请号：US11884617
申请日：2006-03-06
申请人： Yasushi Kohno , David Roger Adams , Naoki Ando
发明人： Yasushi Kohno , David Roger Adams , Naoki Ando
IPC分类号： C07D401/14 , A61P7/02 , A61P9/00 , A61P11/06 , A61P15/00 , A61P25/00 , A61P29/00 , A61P37/08 , A61P43/00
CPC分类号： C07D471/04
摘要： Novel pyrazolopyridine-4-yl pyridazinone derivatives serve as phosphodiesterase inhibitors and are useful compounds for use in pharmaceutical products.Specifically, the compounds of the present invention are pyrazolopyridine-4-yl pyridazinone derivatives represented by the following general formula (1): (Example: 6-(2-ethyl-7-methoxy-pyrazolo[1,5-a]pyridine-4-yl)-5-methyl-4, 5-dihydro-3(2H)-pyridazinone).
摘要翻译：新的吡唑并吡啶-4-基哒嗪酮衍生物用作磷酸二酯酶抑制剂，并且是用于药物产品的有用化合物。具体地说，本发明的化合物是由以下通式（1）表示的吡唑并吡啶-4-基哒嗪酮衍生物：（实施例：6-（2-乙基-7-甲氧基 - 吡唑并[1,5-a] 吡啶-4-基）-5-甲基-4,5-二氢-3（2H） - 哒嗪酮）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式