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41. 发明授权

US06481262B2 Stent crimping tool 失效
标题翻译：支架压接工具
公开(公告)号：US06481262B2
公开(公告)日：2002-11-19
申请号：US09886840
申请日：2001-06-20
申请人： Denise Ching , Richard S. Stack
发明人： Denise Ching , Richard S. Stack
IPC分类号： B21D3904
CPC分类号： A61F2/958 , A61F2002/9522 , Y10T29/53987
摘要： A stent crimping device for crimping a stent onto a balloon delivery-catheter of the kind typically used in percutaneous transluminal coronary angioplasty procedures. The device comprises a pair of plates bearing mutually opposed parallel ribs. The ribbed plates move in a direction such that a stepped circular crimp may be rolled onto a stent thereby firmly fixing the stent to a catheter balloon.
摘要翻译：一种用于将支架卷曲到通常用于经皮冠状动脉内冠状动脉成形术程序的球囊输送导管上的支架卷曲装置。该装置包括一对支承相互相对的平行肋的板。肋板沿着使得阶梯式圆形卷曲可滚动到支架上的方向移动，从而将支架牢固地固定到导管球囊上。

42. 发明授权

US06264683B1 Stent delivery catheter with bumpers for improved retention of balloon expandable stents 有权
标题翻译：具有保险杠的支架输送导管，用于改善球囊扩张支架的保留
公开(公告)号：US06264683B1
公开(公告)日：2001-07-24
申请号：US09527720
申请日：2000-03-17
申请人： Richard S. Stack , Denise Ching
发明人： Richard S. Stack , Denise Ching
IPC分类号： A61F206
CPC分类号： A61F2/958
摘要： An improved balloon catheter which includes bumpers located adjacent to the proximal and distal ends of the catheter balloon. The bumpers form a recessed pocket into which a stent crimped onto the catheter balloon is mounted. The recessed pocket formed by the bumpers securely retains the stent on the balloon and minimizes undesired contact between the stent and arterial walls and lesions during advancement of the stent within a patient's vasculature.
摘要翻译：一种改进的气囊导管，其包括邻近导管球囊的近端和远端定位的缓冲器。保险杠形成凹入的口袋，其中安装有压接在导管球囊上的支架。由保险杠形成的凹槽可将支架牢固地保持在球囊上，并使支架在动脉壁内和病变之间的期望接触最小化，使其在患者的脉管系统内的支架前进。

43. 发明授权

US6165196A Perfusion-occlusion apparatus 失效
标题翻译：灌注闭塞装置
公开(公告)号：US6165196A
公开(公告)日：2000-12-26
申请号：US161067
申请日：1998-09-25
申请人： Richard S. Stack , Francis G. Duhaylongsod , Harry R. Phillips, III , Troy Chapman , Michael Hogendijk , Hugh L. Narciso, Jr.
发明人： Richard S. Stack , Francis G. Duhaylongsod , Harry R. Phillips, III , Troy Chapman , Michael Hogendijk , Hugh L. Narciso, Jr.
IPC分类号： A61B17/11 , A61F2/06 , A61M29/02 , A61M29/00
CPC分类号： A61B17/11 , A61F2/064 , A61M2025/1052 , A61M2025/1097
摘要： A perfusion-occlusion catheter provides an occluded region in a vessel to facilitate, for example, an anastomosis in the region, while providing a path for perfusing fluid (blood) through the path for delivery in the vessel downstream from the occluded region. According to one aspect of the invention, at least a portion of the catheter that effects vessel occlusion comprises a shield that when exposed to suture needles or like piercing instruments deflects or resists perforation.
摘要翻译：灌注闭塞导管在血管中提供封闭区域，以促进例如该区域的吻合，同时提供通过路径灌注流体（血液）的路径以在封闭区域下游的血管输送。根据本发明的一个方面，导管的至少一部分实现血管闭塞包括一个屏蔽，当暴露于缝合针或类似的穿刺器械偏转或抵抗穿孔时。

44. 发明授权

US4867156A Percutaneous axial atheroectomy catheter assembly and method of using the same 失效
标题翻译：经皮轴向动脉粥样硬化切除术导管组装及其使用方法
公开(公告)号：US4867156A
公开(公告)日：1989-09-19
申请号：US66344
申请日：1987-06-25
申请人： Richard S. Stack , James H. McElhaney
发明人： Richard S. Stack , James H. McElhaney
IPC分类号： A61B17/22
CPC分类号： A61B17/3207 , A61B17/32075
摘要： A percutaneous axial atheroectomy catheter assembly for circumferentially removing plaque from coronary arteries including first and second circumferential cutters for cutting first and second radial portions of plaque from the walls of an obstructed vessel and for receiving the excised plaque for removal from the targeted coronary artery.
摘要翻译：一种经皮轴向动脉粥样硬化切除术导管组件，用于从包括第一和第二圆周切割器的冠状动脉周向移除斑块，用于从阻塞血管的壁切割牙斑的第一和第二径向部分并接收用于从目标冠状动脉移除的切除斑块。

45. 发明授权

US09867838B2 Methods for treating heart failure using bisphosphonate compositions 有权
公开(公告)号：US09867838B2
公开(公告)日：2018-01-16
申请号：US13393248
申请日：2010-09-01
申请人： Kenneth W. Lyles , Cathleen S. Colon-Emeric , Christopher M. O'Connor , Richard S. Stack , Colleen Stack
发明人： Kenneth W. Lyles , Cathleen S. Colon-Emeric , Christopher M. O'Connor , Richard S. Stack , Colleen Stack
IPC分类号： A61K47/00 , A61K31/663 , A61K31/66
CPC分类号： A61K31/663 , A61K31/66
摘要： The present invention provides for methods for treating and/or reducing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.

46. 发明授权

US08428730B2 Transvascular electrode system and method 有权
标题翻译：血管电极系统及方法
公开(公告)号：US08428730B2
公开(公告)日：2013-04-23
申请号：US13286217
申请日：2011-11-01
申请人： Richard S. Stack , Michael S. Williams , Daniel W. Fifer , Richard A. Glenn , Geoffrey A. Orth , Lynn Elliott , Colleen Stack N'diaye
发明人： Richard S. Stack , Michael S. Williams , Daniel W. Fifer , Richard A. Glenn , Geoffrey A. Orth , Lynn Elliott , Colleen Stack N'diaye
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36114 , A61N1/36117 , A61N2007/0043
摘要： A transvascular electrode system includes an expandable electrode-carrying anchor. The anchor is intravascularly advanced in a compressed position to a first site in a blood vessel. A first portion of the anchor expands to position an electrode against the vessel wall, while a second portion remains is compressed. Mapping is performed by delivering stimulation energy from the electrode and measuring the response (e.g. blood pressure, heart rate, and/or related parameters). The first portion is at least partially collapsed and the electrode system is moved to a second site. The first portion is expanded to position the electrode into against the vessel wall, while the second portion remains compressed. Additional mapping is performed. The process is repeated until the anchor electrode position is optimized, at which point the second portion of the anchor is expanded to chronically retain the electrode in the vessel.
摘要翻译：经血管电极系统包括可扩张电极承载锚。锚固体在压缩位置中血管内前进到血管中的第一部位。锚的第一部分膨胀以将电极定位在血管壁上，而第二部分保留被压缩。通过从电极传递刺激能量并测量反应（例如血压，心率和/或相关参数）来进行测绘。第一部分至少部分地折叠并且电极系统移动到第二部位。第一部分被扩展以将电极定位在血管壁上，而第二部分保持压缩。执行附加映射。重复该过程直到锚定位置被优化，此时锚固体的第二部分被膨胀以将电极长期地保持在容器中。

47. 发明申请

US20120208786A1 BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE 有权
标题翻译：二磷酸盐组合物和治疗心脏衰竭的方法
公开(公告)号：US20120208786A1
公开(公告)日：2012-08-16
申请号：US13393248
申请日：2010-09-01
申请人： Kenneth W. Lyles , Cathleen S. Colon-Emeric , Christopher M. O'Connor , Richard S. Stack , Colleen Stack
发明人： Kenneth W. Lyles , Cathleen S. Colon-Emeric , Christopher M. O'Connor , Richard S. Stack , Colleen Stack
IPC分类号： A61K31/675 , A61P9/00 , C07F9/40
CPC分类号： A61K31/663 , A61K31/66
摘要： The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.
摘要翻译：本发明提供了治疗和/或预防心脏功能障碍的方法和组合物，其通过施用治疗有效量的双膦酸盐，其功能类似物或药学上有效的盐。

48. 发明授权

US08177853B2 Satiation devices and methods 有权
公开(公告)号：US08177853B2
公开(公告)日：2012-05-15
申请号：US13247400
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61F2/04 , A61M5/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

49. 发明申请

US20120022430A1 SATIATION DEVICES AND METHODS 有权
公开(公告)号：US20120022430A1
公开(公告)日：2012-01-26
申请号：US13247377
申请日：2011-09-28
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, JR.
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

50. 发明授权

US07892292B2 Positioning tools and methods for implanting medical devices 有权
标题翻译：用于植入医疗器械的定位工具和方法
公开(公告)号：US07892292B2
公开(公告)日：2011-02-22
申请号：US11479204
申请日：2006-06-30
申请人： Richard S. Stack , Richard A. Glenn , Dan Balbierz , John Lunsford , William L. Athas
发明人： Richard S. Stack , Richard A. Glenn , Dan Balbierz , John Lunsford , William L. Athas
IPC分类号： A61F2/04
CPC分类号： A61F5/0089 , A61F5/0079
摘要： Described herein is a positioning tool having an elongate portion for carrying a medical implant. Also described is a method of positioning a medical implant using an elongate positioning tool. One form of the method includes positioning a medical implant on a distal portion of an elongate positioning tool, inserting the positioning tool with the implant thereon into a body cavity, manipulating the positioning tool to position the implant into contact with tissue at an attachment location, attaching the implant to surrounding tissue at the attachment location, separating the implant from the positioning tool, and withdrawing the positioning tool from the body. In a preferred embodiment, the position of the implant is visually confirmed using an endoscope before the implant is attached to surrounding tissue. In one embodiment, the implant is a satiation device and the body cavity is the esophagus and/or stomach. In an alternative embodiment, an expansion structure on the distal end of the elongate portion expands and/or contracts the medical implant to facilitate positioning.
摘要翻译：本文描述的是具有用于承载医用植入物的细长部分的定位工具。还描述了使用细长定位工具定位医疗植入物的方法。该方法的一种形式包括将医疗植入物定位在细长定位工具的远侧部分上，将定位工具与其上的植入物插入体腔中，操纵定位工具以使植入物在附着位置与组织接触，将植入物附接到附接位置处的周围组织，将植入物与定位工具分离，并将定位工具从身体上取出。在优选实施例中，在植入物附接到周围组织之前，使用内窥镜在视觉上确认植入物的位置。在一个实施例中，植入物是饱食装置，并且体腔是食道和/或胃。在替代实施例中，细长部分的远端上的膨胀结构使医疗植入物膨胀和/或收缩以便于定位。

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