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41. 发明申请

US20060157067A1 Attenuation of environmental parameters on a gastric lumen 有权
标题翻译：胃管内环境参数的衰减
公开(公告)号：US20060157067A1
公开(公告)日：2006-07-20
申请号：US11035702
申请日：2005-01-14
申请人： Vahid Saadat , Ruey-Feng Peh , Richard Ewers , Eugene Chen
发明人： Vahid Saadat , Ruey-Feng Peh , Richard Ewers , Eugene Chen
IPC分类号： A61B19/00
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00495 , A61B2017/0406 , A61B2017/0454 , A61B2017/0464
摘要： The attenuation or isolation of environmental parameters on a gastric lumen is described herein. Once tissue plications are formed into a gastric lumen or sleeve within a stomach, the newly formed lumen is subjected to a multitude of fluctuating stresses or pressure from food or fluids passing therethrough, from naturally-occurring contractions, and/or from changes in pH levels from caustic stomach acids and hormones. The tissue interface between these plications can be isolated from such environmental fluctuations, or the fluctuations can be attenuated, by a number of methods. One example is to place a gastric stent or sleeve within the newly formed lumen. Another example is to utilize multiple rows of anchors, clips, or sutures along the interface. Alternatively, bio-adhesives can be dispensed to buttress the tissue interface. In another variation, the tissue can be approximated in different configurations which effectively reduce or isolate the adhered tissue region.
摘要翻译：本文描述了在胃腔上的环境参数的衰减或分离。一旦组织消融在胃内形成胃腔或套管，则新形成的内腔经受来自通过其的食物或液体的多种波动的压力或压力，从天然存在的收缩和/或pH水平的变化从苛性胃酸和激素。可以通过多种方法将这些斑点之间的组织界面与这种环境波动隔离，或者波动可以减弱。一个例子是将胃支架或套管放置在新形成的内腔内。另一个例子是沿着界面使用多行锚，剪辑或缝线。或者，可以分配生物粘合剂以支撑组织界面。在另一个实施方式中，可以以有效地减少或隔离粘附的组织区域的不同配置来近似组织。

42. 发明申请

US20050203500A1 Apparatus and methods for mapping out endoluminal gastrointestinal surgery 有权
标题翻译：用于绘制腔内胃肠手术的装置和方法
公开(公告)号：US20050203500A1
公开(公告)日：2005-09-15
申请号：US10954658
申请日：2004-09-29
申请人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh , Richard Ewers
发明人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh , Richard Ewers
IPC分类号： A61B17/00 , A61B18/04 , A61B19/00
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/12013 , A61B17/320016 , A61B17/32053 , A61B17/32075 , A61B17/3211 , A61B17/3478 , A61B18/14 , A61B18/1482 , A61B18/1492 , A61B90/39 , A61B2017/00269 , A61B2017/00349 , A61B2017/00818 , A61B2017/00986 , A61B2017/0411 , A61B2017/0419 , A61B2017/06052 , A61B2017/306 , A61B2017/308 , A61B2017/320044 , A61B2018/00029 , A61B2018/00244 , A61B2018/00291 , A61B2018/00494 , A61B2018/00577 , A61B2018/00595 , A61B2018/00982 , A61B2018/124 , A61B2018/1415 , A61B2018/144 , A61B2018/1467 , A61B2090/036 , A61B2090/3908 , A61B2090/3912 , A61B2090/3937 , A61B2090/395 , A61B2090/3987 , A61B2090/3991 , A61B2218/002 , A61B2218/007 , A61F5/0013
摘要： Apparatus and methods are provided for mapping out endoluminal gastrointestinal surgery, including endoluminal gastric reduction. Mapping is achieved by locally marking the interior of the gastrointestinal lumen at specified locations. In some variations, mucosectomy and/or mucosal ablation are performed to map out endoluminal GI surgery, to facilitate direct endoluminal engagement of underlying muscularis tissue and/or to initiate a wound healing response. Specialized apparatus may be provided to achieve desired spacing and/or positioning of tissue markings, as well as to actually form the markings. Methods of using apparatus of the present invention are provided.
摘要翻译：提供装置和方法用于映射腔内胃肠手术，包括腔内胃减少。通过在指定位置局部标记胃肠腔的内部来实现测绘。在一些变型中，进行粘膜切除术和/或粘膜消融以绘出腔内GI手术，以促进下面的肌层组织的直接腔内接合和/或引发伤口愈合反应。可以提供专用设备以实现组织标记的期望的间隔和/或定位，以及实际形成标记。提供了使用本发明装置的方法。

43. 发明授权

US08934962B2 Electrophysiology mapping and visualization system 有权
标题翻译：电生理测绘和可视化系统
公开(公告)号：US08934962B2
公开(公告)日：2015-01-13
申请号：US11848532
申请日：2007-08-31
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
IPC分类号： A61B5/00 , A61B17/34 , A61B1/00 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02 , A61B5/042 , A61B17/12 , A61B19/00 , A61B8/12 , A61B8/00 , A61B17/04 , A61B17/221 , A61B18/02 , A61B17/00 , A61B17/22 , A61B18/00
CPC分类号： A61B5/0084 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/0031 , A61B5/02007 , A61B5/0422 , A61B5/6882 , A61B8/12 , A61B8/4472 , A61B17/0487 , A61B17/12045 , A61B17/221 , A61B17/3415 , A61B17/3423 , A61B18/02 , A61B34/20 , A61B34/30 , A61B90/36 , A61B2017/00044 , A61B2017/00053 , A61B2017/00296 , A61B2017/003 , A61B2017/00575 , A61B2017/0409 , A61B2017/0477 , A61B2017/12127 , A61B2017/22038 , A61B2017/22054 , A61B2017/22067 , A61B2017/22069 , A61B2017/22082 , A61B2017/3445 , A61B2017/3484 , A61B2017/3488 , A61B2018/00982 , A61B2018/0212 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2090/306 , A61B2090/309 , A61B2090/3614 , A61B2090/373 , A61B2090/3958 , A61M5/007
摘要： Electrophysiology mapping and visualization systems are described herein where such devices may be used to visualize tissue regions as well as map the electrophysiological activity of the tissue. Such a system may include a deployment catheter and an attached hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. A position of the catheter and/or hood may be tracked and the hood may also be used to detect the electrophysiological activity of the visualized tissue for mapping.
摘要翻译：本文描述了电生理学测绘和可视化系统，其中这样的装置可用于可视化组织区域以及映射组织的电生理活性。这样的系统可以包括部署导管和可展开成展开配置的连接的罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。可以跟踪导管和/或罩的位置，并且罩也可用于检测可视化组织的电生理活动以进行映射。

44. 发明授权

US08087413B2 Attenuation of environmental parameters on a gastric lumen 有权
标题翻译：胃管内环境参数的衰减
公开(公告)号：US08087413B2
公开(公告)日：2012-01-03
申请号：US11035702
申请日：2005-01-14
申请人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
发明人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
IPC分类号： A61B19/00 , A61B17/08 , A61B17/04 , A61F2/04 , A61L17/00
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00495 , A61B2017/0406 , A61B2017/0454 , A61B2017/0464
摘要： The attenuation or isolation of environmental parameters on a gastric lumen is described herein. Once tissue plications are formed into a gastric lumen or sleeve within a stomach, the newly formed lumen is subjected to a multitude of fluctuating stresses or pressure from food or fluids passing therethrough, from naturally-occurring contractions, and/or from changes in pH levels from caustic stomach acids and hormones. The tissue interface between these plications can be isolated from such environmental fluctuations, or the fluctuations can be attenuated, by a number of methods. One example is to place a gastric stent or sleeve within the newly formed lumen. Another example is to utilize multiple rows of anchors, clips, or sutures along the interface. Alternatively, bio-adhesives can be dispensed to buttress the tissue interface. In another variation, the tissue can be approximated in different configurations which effectively reduce or isolate the adhered tissue region.
摘要翻译：本文描述了在胃腔上的环境参数的衰减或分离。一旦组织消融在胃内形成胃腔或套管，则新形成的内腔经受来自通过其的食物或液体的多种波动的应力或压力，从天然存在的收缩和/或pH水平的变化从苛性胃酸和激素。可以通过多种方法将这些斑点之间的组织界面与这种环境波动隔离，或者波动可以减弱。一个例子是将胃支架或套管放置在新形成的内腔内。另一个例子是沿着界面使用多行锚，剪辑或缝线。或者，可以分配生物粘合剂以支撑组织界面。在另一个实施方式中，可以以有效地减少或隔离粘附的组织区域的不同配置来近似组织。

45. 发明申请

US20050277945A1 Apparatus and methods for performing transluminal gastrointestinal procedures 有权
标题翻译：用于执行经腔胃肠道手术的装置和方法
公开(公告)号：US20050277945A1
公开(公告)日：2005-12-15
申请号：US10918217
申请日：2004-08-11
申请人： Vahid Saadat , Ruey-Feng Peh
发明人： Vahid Saadat , Ruey-Feng Peh
IPC分类号： A61B17/00 , A61B17/06 , A61B17/10
CPC分类号： A61B17/06166 , A61B2017/00278 , A61B2017/00349 , A61B2017/00761 , A61B2017/06057 , A61B2017/06176
摘要： Methods and apparatus are provided for diagnosing and treating digestive or other organs (as well as other parts of the body) endoluminally and transluminally, via instruments passed into the GI tract per-orally and/or per-anally. The instruments may, for example, pass transluminally out of the stomach and/or the colon through a breach formed therein in order to conduct diagnostic or therapeutic procedures, such as gastroenterostomy.
摘要翻译：提供方法和装置，用于通过口服和/或每次通过胃肠道的器械来诊断和治疗消化系统或其他器官（以及身体其他部位）。例如，器械可以通过其中形成的破裂从胃和/或结肠中透明地通过，以进行诊断或治疗程序，例如胃肠造口术。

46. 发明申请

US20050251157A1 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US20050251157A1
公开(公告)日：2005-11-10
申请号：US10840950
申请日：2004-05-07
申请人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
发明人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚固件之间的组织褶皱的收紧，并且可以在一个或多个锚固件中使用紧固组织褶皱。

47. 发明授权

US08308765B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US08308765B2
公开(公告)日：2012-11-13
申请号：US10840950
申请日：2004-05-07
申请人： Vahid Saadat , Tracy D. Maahs , Richard C. Ewers , Marvin C. Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang C. Lam
发明人： Vahid Saadat , Tracy D. Maahs , Richard C. Ewers , Marvin C. Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang C. Lam
IPC分类号： A61B17/04
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：用于定位和固定锚固件的装置和方法适于被输送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚固件之间的组织褶皱的收紧，并且可以在一个或多个锚固件中使用紧固组织褶皱。

48. 发明授权

US08057511B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US08057511B2
公开(公告)日：2011-11-15
申请号：US10841411
申请日：2004-05-07
申请人： Jesus Flores , Richard C. Ewers , Tracy D. Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
发明人： Jesus Flores , Richard C. Ewers , Tracy D. Maahs , Alex Khairkhahan , Ruey-Feng Peh , Vahid Saadat
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0487 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0488 , A61B2017/0496 , A61B2017/06028 , A61B2017/06052 , A61B2017/06176 , Y10T24/39 , Y10T24/3969
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚定器之间的组织褶皱收紧，并且可以在一个或多个锚定器中使用，以收紧组织褶皱。

49. 发明申请

US20090054803A1 ELECTROPHYSIOLOGY MAPPING AND VISUALIZATION SYSTEM 有权
标题翻译：电生理映射和可视化系统
公开(公告)号：US20090054803A1
公开(公告)日：2009-02-26
申请号：US11848532
申请日：2007-08-31
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
IPC分类号： A61B5/04
CPC分类号： A61B5/0084 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/0031 , A61B5/02007 , A61B5/0422 , A61B5/6882 , A61B8/12 , A61B8/4472 , A61B17/0487 , A61B17/12045 , A61B17/221 , A61B17/3415 , A61B17/3423 , A61B18/02 , A61B34/20 , A61B34/30 , A61B90/36 , A61B2017/00044 , A61B2017/00053 , A61B2017/00296 , A61B2017/003 , A61B2017/00575 , A61B2017/0409 , A61B2017/0477 , A61B2017/12127 , A61B2017/22038 , A61B2017/22054 , A61B2017/22067 , A61B2017/22069 , A61B2017/22082 , A61B2017/3445 , A61B2017/3484 , A61B2017/3488 , A61B2018/00982 , A61B2018/0212 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2090/306 , A61B2090/309 , A61B2090/3614 , A61B2090/373 , A61B2090/3958 , A61M5/007
摘要： Electrophysiology mapping and visualization systems are described herein where such devices may be used to visualize tissue regions as well as map the electrophysiological activity of the tissue. Such a system may include a deployment catheter and an attached hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. A position of the catheter and/or hood may be tracked and the hood may also be used to detect the electrophysiological activity of the visualized tissue for mapping.
摘要翻译：本文描述了电生理学测绘和可视化系统，其中这样的装置可用于可视化组织区域以及映射组织的电生理活性。这样的系统可以包括部署导管和可展开成展开配置的连接的罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。可以跟踪导管和/或罩的位置，并且罩也可用于检测可视化组织的电生理活动以进行映射。

50. 发明申请

US20060161185A1 Methods and apparatus for transmitting force to an end effector over an elongate member 审中-公开
标题翻译：用于在细长构件上向末端执行器传递力的方法和装置
公开(公告)号：US20060161185A1
公开(公告)日：2006-07-20
申请号：US11035993
申请日：2005-01-14
申请人： Vahid Saadat , Richard Ewers , Ruey-Feng Peh , Tracy Maahs
发明人： Vahid Saadat , Richard Ewers , Ruey-Feng Peh , Tracy Maahs
IPC分类号： A61B17/08
CPC分类号： A61B17/0487 , A61B17/00234 , A61B17/0469 , A61B17/29 , A61B2017/00349 , A61B2017/00371 , A61B2017/00398 , A61B2017/00535 , A61B2017/00553 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06028 , A61B2017/06052 , A61B2017/06076 , A61B2017/2927
摘要： Apparatus and methods for conveying or transmitting force or energy to a medical end effector coupled to a flexible or rigid shaft are described herein. One variation of such apparatus may be used to manipulate tissue and create a tissue fold and may generally comprise an elongate tubular member having an end effector disposed thereon. The end effector may comprise a tissue engagement member adapted to engage tissue, a first stabilizing member and a second stabilizing member positioned at the tubular member distal end, and a launch tube adapted to pivot about the first stabilizing member. Elements of the end effector may be actuable via various force transmission elements and/or mechanisms. Such force transmission elements preferably are integrated into and/or are actuable via a handle. The force transmission mechanisms may be utilized to actuate and/or transmit force to alternative medical end effectors coupled to flexible or rigid shafts.
摘要翻译：这里描述了用于将力或能量传送或传递到耦合到柔性或刚性轴的医疗端部执行器的装置和方法。这种装置的一个变型可用于操纵组织并产生组织折叠，并且通常可包括其上设置有末端执行器的细长管状构件。末端执行器可以包括适于接合组织的组织接合构件，定位在管状构件远端的第一稳定构件和第二稳定构件，以及适于围绕第一稳定构件枢转的发射管。端部执行器的元件可以通过各种力传递元件和/或机构致动。这种力传递元件优选地通过手柄集成到和/或可致动。力传递机构可以用于致动和/或传递力到耦合到柔性或刚性轴的替代医疗端部执行器。

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