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    • 47. 发明授权
    • Method and apparatus for examining vascular endothelial functions
    • 检查血管内皮功能的方法和装置
    • US07131949B2
    • 2006-11-07
    • US10822843
    • 2004-04-13
    • Junichiro HayanoToshihiko Ogura
    • Junichiro HayanoToshihiko Ogura
    • A61B5/00
    • A61B5/02007A61B5/0285
    • Vascular endothelial function in terms of flow-mediated dilation (FMD) of peripheral arteries can be assessed reliably by measuring beat-to-beat pulse-wave conduction time (PCT) simultaneously for two symmetric segments of arteries locating on the right and left sides of body. When reactive hyperemia is induced in the peripheral tissues on one side, the time dependent changes in PCT caused by FMD on that side can be detected as the beat-to-beat differences in PCT between two sides (ΔPCT). ΔPCT would provide a sensitive and specific assessment of the FMD response, because the influences of the systemic changes in hemodynamic and neurohumoral factors common to both sides are subtracted out. In addition, measurement of PCT requires no skillful technique and is advantageous in that the apparatus is inexpensive.
    • 通过测量位于左右两侧的动脉对称段同时测量搏动脉搏波导通时间(PCT),可以可靠地评估外周动脉血流内皮扩张(FMD)方面的血管内皮功能。 身体。 当在一侧的外周组织中诱导反应性充血时,由该侧FMD引起的PCT的时间依赖性变化可以被检测为双侧(DeltaPCT)之间的PCT中的搏动间差异。 DeltaPCT将对FMD反应进行敏感和具体的评估,因为减少了双方共同的血液动力学和神经体液因素的全身变化的影响。 此外,PCT的测量不需要熟练的技术,并且是有利的,因为该设备是便宜的。
    • 49. 发明授权
    • Superior-and-inferior-limb blood-pressure index measuring apparatus
    • 上肢和下肢血压指标测量装置
    • US06355000B1
    • 2002-03-12
    • US09556417
    • 2000-04-24
    • Toshihiko Ogura
    • Toshihiko Ogura
    • A61B502
    • A61B5/02225A61B5/022
    • An apparatus for measuring a superior-and-inferior-limb blood-pressure index of a living subject, including a first blood-pressure measuring device which measures a first blood pressure of an inferior limb of the subject, a second blood-pressure measuring device which measures a second blood pressure of a superior limb of the subject, an index determining device for determining the superior-and-inferior-limb blood-pressure index, based on the first blood pressure measured by the first blood-pressure measuring device and the second blood pressure measured by the second blood-pressure measuring device, an information obtaining device which obtains propagation-velocity-relating information relating to a velocity of propagation of a pulse wave which propagates between two different portions of the subject, and a display device which simultaneously displays the superior-and-inferior-limb blood-pressure index determined by the index determining device and the propagation-velocity-relating information obtained by the information obtaining device.
    • 一种用于测量生物体的上肢和下肢血压指数的装置,包括测量被检体下肢的第一血压的第一血压测量装置,第二血压测量装置 其测量对象的上肢的第二血压,基于由第一血压测量装置测量的第一血压和/或第二血压测量装置测定的上肢和下肢血压指数的指标确定装置, 由第二血压测量装置测量的第二血压,获得与在对象的两个不同部分之间传播的脉搏波的传播速度相关的传播速度相关信息的信息获取装置,以及显示装置, 同时显示由指标确定装置确定的上肢和下肢血压指数和传播速度相关 由信息获取装置获得的数据。