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41. 发明申请

US20090138007A1 HIGH-SENSITIVITY PRESSURE-SENSING PROBE 有权
标题翻译：高灵敏度感应探头
公开(公告)号：US20090138007A1
公开(公告)日：2009-05-28
申请号：US12327226
申请日：2008-12-03
申请人： Assaf Govari , Yaron Ephrath , Ariel Garcia , Andres Claudio Altmann
发明人： Assaf Govari , Yaron Ephrath , Ariel Garcia , Andres Claudio Altmann
IPC分类号： A61B18/18
CPC分类号： A61B5/48 , A61B1/0008 , A61B5/06 , A61B5/065 , A61B5/6885 , A61B18/1492 , A61B2018/00351 , A61B2034/2051 , A61B2090/064 , A61B2090/065 , A61B2090/3958 , A61B2562/0247 , A61N1/056 , A61N1/08
摘要： A medical probe includes an insertion tube, having a longitudinal axis and having a distal end. A distal tip is disposed at the distal end of the insertion tube and is configured to be brought into contact with a body tissue. A joint couples the distal tip to the distal end of the insertion tube. A joint sensor, contained within the probe, senses a position of the distal tip relative to the distal end of the insertion tube. The joint sensor includes first and second subassemblies, which are disposed within the probe on opposite, respective sides of the joint and each include one or more magnetic transducers.
摘要翻译：医疗探针包括具有纵向轴线并具有远端的插入管。远侧末端设置在插入管的远端，并被构造成与身体组织接触。关节将远侧末端连接到插入管的远端。包含在探针内的关节传感器感测远侧末端相对于插入管的远端的位置。联合传感器包括第一和第二子组件，其在接头的相对的相对侧设置在探针内，并且每个包括一个或多个磁性换能器。

42. 发明授权

US07536218B2 Hybrid magnetic-based and impedance-based position sensing 有权
标题翻译：基于混合磁性和基于阻抗的位置检测
公开(公告)号：US07536218B2
公开(公告)日：2009-05-19
申请号：US11182272
申请日：2005-07-15
申请人： Assaf Govari , Andres Claudio Altmann , Yitzhack Schwartz , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yitzhack Schwartz , Yaron Ephrath
IPC分类号： A61B5/05
CPC分类号： A61B5/063 , A61B5/0035 , A61B5/0538
摘要： A position sensing system includes a probe adapted to be introduced into a body cavity of a subject. The probe includes a magnetic field transducer and at least one probe electrodes. A control unit is configured to measure position coordinates of the probe using the magnetic field transducer. The control unit also measures an impedance between the at least one probe electrodes and one or more points on a body surface of the subject. Using the measured position coordinates, the control unit calibrates the measured impedance.
摘要翻译：位置感测系统包括适于被引入被检体体腔的探头。探头包括磁场换能器和至少一个探针电极。控制单元被配置为使用磁场换能器来测量探头的位置坐标。控制单元还测量至少一个探针电极与被检体的身体表面上的一个或多个点之间的阻抗。使用测量的位置坐标，控制单元校准测量的阻抗。

43. 发明授权

US10456196B2 Monitoring and tracking bipolar ablation 有权
公开(公告)号：US10456196B2
公开(公告)日：2019-10-29
申请号：US13326456
申请日：2011-12-15
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B18/14
摘要： Methods and systems treat abnormal cardiac electrical activity employing a probe having first and second ablation electrodes disposed on a distal portion of the probe and a sensing electrode disposed between the first and second ablation electrodes, bringing the probe into contact with cardiac tissue, and applying energy through the first and second ablation electrodes to ablate target tissue along an ablation path, monitoring cardiac electrical activity using the sensing electrode to detect the cardiac electrical activity. After making an observation that the cardiac electrical activity is no longer detectable by the sensing electrode, energy application is terminated.

44. 发明授权

US09687289B2 Contact assessment based on phase measurement 有权
公开(公告)号：US09687289B2
公开(公告)日：2017-06-27
申请号：US13343024
申请日：2012-01-04
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B18/00 , A61B18/12 , A61B18/14 , A61B90/00
CPC分类号： A61B18/12 , A61B18/1492 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2018/1467 , A61B2090/065
摘要： Methods and systems achieve tissue ablation, which is carried out by inserting a probe having an ablation electrode into a body of a living subject, and while the ablation electrode is in a non-contacting relationship to a target tissue, making a pre-contact determination of a phase of an electrical current passing between the ablation electrode and another electrode. The ablation electrode is placed in contact with the target tissue, and while the ablation electrode is in the contacting relationship, a dosage of energy is applied via the ablation electrode to the target tissue for ablation thereof. Iterative intra-operative determinations of the phase of the electrical current are made. When one of the intra-operative determinations satisfies a termination criterion, the energy application is terminated.

45. 发明授权

US09247985B2 Test jig for ablator 有权
标题翻译：消除器测试夹具
公开(公告)号：US09247985B2
公开(公告)日：2016-02-02
申请号：US13191842
申请日：2011-07-27
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath , Tom Sagie Stern
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath , Tom Sagie Stern
IPC分类号： G01K15/00 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1233 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00755 , A61B2018/00791 , A61B2018/00821 , A61B2018/00875
摘要： In techniques for testing and calibrating an ablator, a tissue probe emulator is connectable to a tissue ablator being tested. The emulator includes a temperature sensor, a thermoelectric unit operative to vary a temperature sensed by the temperature sensor, an adjustable electrical load, electrical control circuitry connected to the thermoelectric unit and the electrical load and operative to independently adjust the electrical load and an output of the thermoelectric unit. The emulator conveys signals emitted by the temperature sensor to the tissue ablator and conveys an ablation energy output of the tissue ablator to the electrical load.
摘要翻译：在用于测试和校准消融器的技术中，组织探针模拟器可连接到被测试的组织消融器。仿真器包括温度传感器，用于改变由温度传感器感测的温度的热电单元，可调电负载，连接到热电单元的电气控制电路和电负载，并可操作以独立地调节电负载和热电单元。仿真器将温度传感器发出的信号传达给组织消融器，并将组织消融器的消融能量输出传递给电气负载。

46. 发明授权

US09005193B2 Multichannel ablation with frequency differentiation 有权
标题翻译：多通道消融与频率分化
公开(公告)号：US09005193B2
公开(公告)日：2015-04-14
申请号：US12951200
申请日：2010-11-22
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B18/04 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1206 , A61B18/1492 , A61B18/16 , A61B2018/00577 , A61B2018/00779 , A61B2018/00821 , A61B2018/00875 , A61B2018/124 , A61B2018/128 , A61B2018/1286 , A61B2018/1467 , A61B2034/2051
摘要： Apparatus, including an energy generator, configured to supply first ablation power modulated at a first frequency and second ablation power modulated at a second frequency different from the first frequency. The apparatus also includes a probe, having at least one electrode coupled to receive the first and second ablation powers simultaneously and to dissipate the first and second ablation powers in body tissue in contact with the at least one electrode.
摘要翻译：包括能量发生器的装置，其被配置为提供以第一频率调制的第一消融功率和以不同于第一频率的第二频率调制的第二消融功率。该装置还包括探针，其具有耦合以同时接收第一和第二消融功率的至少一个电极并且消散与至少一个电极接触的身体组织中的第一和第二消融功率。

47. 发明授权

US08730011B2 Wireless position transducer with digital signaling 有权
标题翻译：带数字信号的无线位置传感器
公开(公告)号：US08730011B2
公开(公告)日：2014-05-20
申请号：US11181256
申请日：2005-07-14
申请人： Andres Claudio Altmann , Assaf Govari , Yaron Ephrath
发明人： Andres Claudio Altmann , Assaf Govari , Yaron Ephrath
IPC分类号： G08B5/22
CPC分类号： G01V15/00 , A61B34/20 , A61B2034/2051
摘要： Apparatus for tracking an object includes a position transducer, which is adapted to be fixed to the object. The position transducer includes a digital microcontroller, which includes a plurality of output pins, and which is operative to generate an alternating digital output at a selected frequency on at least one of the output pins. At least one transmit antenna is coupled directly to the at least one of the output pins, so that the at least one antenna transmits a magnetic field at the selected frequency responsively to the alternating digital output. A field sensor senses the magnetic field and generates a signal responsively thereto. A processor receives and processes the signal in order to determine coordinates of the position transducer.
摘要翻译：用于跟踪物体的装置包括适于固定在物体上的位置传感器。位置传感器包括数字微控制器，其包括多个输出引脚，并且其可操作以在至少一个输出引脚上以选定的频率产生交替数字输出。至少一个发射天线直接耦合到至少一个输出引脚，使得至少一个天线响应于交替数字输出以选定频率发射磁场。场感测器感测磁场并响应于此产生信号。处理器接收并处理信号以便确定位置传感器的坐标。

48. 发明授权

US08535308B2 High-sensitivity pressure-sensing probe 有权
标题翻译：高灵敏度压力传感探头
公开(公告)号：US08535308B2
公开(公告)日：2013-09-17
申请号：US12327226
申请日：2008-12-03
申请人： Assaf Govari , Yaron Ephrath , Ariel Garcia , Andres Claudio Altmann
发明人： Assaf Govari , Yaron Ephrath , Ariel Garcia , Andres Claudio Altmann
IPC分类号： A61B18/18 , A61B5/05
CPC分类号： A61B5/48 , A61B1/0008 , A61B5/06 , A61B5/065 , A61B5/6885 , A61B18/1492 , A61B2018/00351 , A61B2034/2051 , A61B2090/064 , A61B2090/065 , A61B2090/3958 , A61B2562/0247 , A61N1/056 , A61N1/08
摘要： A medical probe includes an insertion tube, having a longitudinal axis and having a distal end. A distal tip is disposed at the distal end of the insertion tube and is configured to be brought into contact with a body tissue. A joint couples the distal tip to the distal end of the insertion tube. A joint sensor, contained within the probe, senses a position of the distal tip relative to the distal end of the insertion tube. The joint sensor includes first and second subassemblies, which are disposed within the probe on opposite, respective sides of the joint and each include one or more magnetic transducers.
摘要翻译：医疗探针包括具有纵向轴线并具有远端的插入管。远侧末端设置在插入管的远端，并被构造成与身体组织接触。关节将远侧末端连接到插入管的远端。包含在探针内的关节传感器感测远侧末端相对于插入管的远端的位置。联合传感器包括第一和第二子组件，其在接头的相对的相对侧设置在探针内，并且每个包括一个或多个磁性换能器。

49. 发明申请

US20130172875A1 CONTACT ASSESSMENT BASED ON PHASE MEASUREMENT 有权
标题翻译：基于相位测量的接触评估
公开(公告)号：US20130172875A1
公开(公告)日：2013-07-04
申请号：US13343024
申请日：2012-01-04
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B18/18
CPC分类号： A61B18/12 , A61B18/1492 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2018/1467 , A61B2090/065
摘要： Methods and systems achieve tissue ablation, which is carried out by inserting a probe having an ablation electrode into a body of a living subject, and while the ablation electrode is in a non-contacting relationship to a target tissue, making a pre-contact determination of a phase of an electrical current passing between the ablation electrode and another electrode. The ablation electrode is placed in contact with the target tissue, and while the ablation electrode is in the contacting relationship, a dosage of energy is applied via the ablation electrode to the target tissue for ablation thereof. Iterative intra-operative determinations of the phase of the electrical current are made. When one of the intra-operative determinations satisfies a termination criterion, the energy application is terminated.
摘要翻译：方法和系统实现组织消融，其通过将具有消融电极的探针插入生物体的体内，并且当消融电极与靶组织处于非接触关系时，进行预接触确定在消融电极和另一电极之间通过电流的相位。消融电极被放置成与靶组织接触，并且当消融电极处于接触关系时，通过消融电极将能量的剂量施加到目标组织以进行烧蚀。进行电流相位的迭代术中确定。当术中确定之一满足终止标准时，终止能量应用。

50. 发明授权

US08260400B2 Model-based correction of position measurements 有权
标题翻译：基于模型的位置测量校正
公开(公告)号：US08260400B2
公开(公告)日：2012-09-04
申请号：US13100369
申请日：2011-05-04
申请人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B1/00 , A61B5/065 , A61B8/0833 , A61B8/0841 , A61B2034/2053
摘要： Visualization of a probe when impedance-based measurement technology is being used is improved by stabilizing a displayed image of the probe or catheter. Using a model of reasonable probe shapes and a matching algorithm, an erroneous probe image is adjusted so that it assumes a realistic shape on a display. A range of positional variations is also incorporated in the model. When an apparent probe position exceeds a permissible range of motion, the probe image is constrained to a realistic position.
摘要翻译：通过稳定探针或导管的显示图像可以改善使用基于阻抗的测量技术时探测器的可视化。使用合理探针形状和匹配算法的模型，调整错误的探针图像，使其在显示器上呈现逼真的形状。模型中还包含一系列位置变化。当表观探头位置超过允许的运动范围时，探头图像被限制到一个现实的位置。

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