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41. 发明授权

US07493160B2 Nano-actuated medical device 有权
标题翻译：纳米致动医疗器械
公开(公告)号：US07493160B2
公开(公告)日：2009-02-17
申请号：US10679049
申请日：2003-10-03
申请人： Jan Weber , Thomas Holman , Tracee E. J. Eidenschink , John J. Chen
发明人： Jan Weber , Thomas Holman , Tracee E. J. Eidenschink , John J. Chen
IPC分类号： A61M1/18
CPC分类号： A61M25/00 , A61B2017/00535 , A61B2017/22051 , A61F2/95 , A61F2002/30075 , A61F2002/30329 , A61F2210/0061 , A61F2220/0025 , A61M25/10 , A61M2025/0057 , A61M2025/0058 , A61M2025/0096 , A61M2025/1086
摘要： A medical device is disclosed which may include the use of nanopaper. The medical device may be provided in the form of a balloon catheter wherein the nanopaper is mounted about an electrode and into which an electrically conductive solution is dispersed. An elastomeric sheath may then be provided about the nanopaper. Actuation of the electrode may cause generation of microbubbles causing the nanopaper to expand.
摘要翻译：公开了一种医疗装置，其可以包括纳米滤器的使用。医疗装置可以以气囊导管的形式提供，其中纳米滤片围绕电极安装并且分散有导电溶液。然后可以围绕纳米滤纸器设置弹性体护套。电极的致动可能引起微泡的产生，导致纳米微孔膨胀。

42. 发明申请

US20070282424A1 Endovascular apparatus 有权
公开(公告)号：US20070282424A1
公开(公告)日：2007-12-06
申请号：US11891934
申请日：2007-08-14
申请人： Thomas Holman , Darlene Thometz , Fertac Bilge , Paul Buscemi , David Donabedian
发明人： Thomas Holman , Darlene Thometz , Fertac Bilge , Paul Buscemi , David Donabedian
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/12045 , A61B17/12118 , A61B2017/00004 , A61B2017/00535 , A61B2017/1205 , A61B2017/12127 , A61F2/89 , A61F2/94 , A61F2/95 , A61F2/954 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2250/0003
摘要： Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.

43. 发明申请

US20070089032A1 Memory system anti-aliasing scheme 审中-公开
标题翻译：内存系统抗锯齿方案
公开(公告)号：US20070089032A1
公开(公告)日：2007-04-19
申请号：US11240823
申请日：2005-09-30
申请人： James Alexander , Joaquin Romera , Rajat Agarwal , Thomas Holman
发明人： James Alexander , Joaquin Romera , Rajat Agarwal , Thomas Holman
IPC分类号： G11C29/00
CPC分类号： G06F11/1024
摘要： Embodiments of the invention are generally directed to systems, methods, and apparatuses for a memory device anti-aliasing scheme. In an embodiment, a memory controller includes an error check agent to receive a codeword from a rank of memory and to provide an error indication in response to detecting a correctable adjacent-symbol-pair-error the rank of memory. An error counter may be coupled with the error check agent to increment towards a threshold value in response to the error indication from the error check agent. In an embodiment, a faulty memory device marker agent coupled with the error counter provides a faulty memory device marker to the error check agent, if the error counter exceeds the threshold value. Other embodiments are described and claimed.
摘要翻译：本发明的实施例一般涉及用于存储器件抗锯齿方案的系统，方法和装置。在一个实施例中，存储器控制器包括错误检查代理，用于从存储器的等级接收码字，并且响应于检测存储器的等级的可校正的相邻符号对错误来提供错误指示。响应于来自错误检查代理的错误指示，错误计数器可以与错误检查代理相结合以递增到阈值。在一个实施例中，如果错误计数器超过阈值，则与错误计数器耦合的故障存储器设备标记代理向错误检查代理提供错误的存储器设备标记。描述和要求保护其他实施例。

44. 发明申请

US20060276881A1 Endovascular apparatus 有权
公开(公告)号：US20060276881A1
公开(公告)日：2006-12-07
申请号：US11493306
申请日：2006-07-26
申请人： Thomas Holman , Darlene Thometz , Fertac Bilge , Paul Buscemi , David Donabedian
发明人： Thomas Holman , Darlene Thometz , Fertac Bilge , Paul Buscemi , David Donabedian
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/12045 , A61B17/12118 , A61B2017/00004 , A61B2017/00535 , A61B2017/1205 , A61B2017/12127 , A61F2/89 , A61F2/94 , A61F2/95 , A61F2/954 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2250/0003
摘要： Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.

45. 发明申请

US20060182907A1 Novel microfibrillar reinforced polymer-polymer composites for use in medical devices 审中-公开
标题翻译：用于医疗器械的新型微纤维增强聚合物 - 聚合物复合材料
公开(公告)号：US20060182907A1
公开(公告)日：2006-08-17
申请号：US11055837
申请日：2005-02-11
申请人： Liliana Atanasoska , Thomas Holman , Victor Schoenle , Robert Warner , Scott Schewe
发明人： Liliana Atanasoska , Thomas Holman , Victor Schoenle , Robert Warner , Scott Schewe
IPC分类号： B31B45/00
CPC分类号： A61M25/1029 , A61M25/0045 , A61M25/005 , A61M25/0052 , A61M25/0053 , A61M25/10 , A61M25/1034 , A61M2025/0047 , A61M2025/1084 , B29C65/16 , B29C65/68 , B29C66/1122 , B29C66/5344 , B29C66/63 , B29L2031/7543 , Y10T428/13 , Y10T428/1372
摘要： A medical device formed at least in part from a microfibrillar polymer-polymer composite, the microfibrillar polymer-polymer composite comprising a polymer matrix and oriented polymer microfibrils, and method of making the same.
摘要翻译：至少部分由微原纤维聚合物 - 聚合物复合材料形成的包含聚合物基质和定向聚合物微原纤维的微原纤维聚合物 - 聚合物复合物的医疗装置及其制备方法。

46. 发明申请

US20060142796A1 Methods and apparatus for emboli removal 失效
标题翻译：栓塞方法和装置
公开(公告)号：US20060142796A1
公开(公告)日：2006-06-29
申请号：US11021381
申请日：2004-12-23
申请人： Jan Weber , Tracee Eidenschink , David Sogard , Joel WasDyke , Thomas Holman
发明人： Jan Weber , Tracee Eidenschink , David Sogard , Joel WasDyke , Thomas Holman
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2/24 , A61F2/2493 , A61F2/86 , A61F2002/018 , A61F2002/068 , A61F2230/0006 , A61F2230/0067
摘要： Improved methods and apparatus for capturing emboli and subsequently removing or immobilizing the captured emboli are described. Emboli can be captured within a blood vessel and can be withdrawn to a position exterior to the blood vessel. Some filters can remain within a blood vessel yet direct emboli to a position exterior to the blood vessel.
摘要翻译：描述了用于捕获栓塞以及随后去除或固定所捕获的栓塞的改进的方法和装置。栓塞可以在血管内捕获并且可以撤回到血管外部的位置。一些过滤器可以保留在血管内，但是直接栓塞到血管外部的位置。

47. 发明申请

US20060125144A1 Stent and stent manufacturing methods 审中-公开
标题翻译：支架和支架制造方法
公开(公告)号：US20060125144A1
公开(公告)日：2006-06-15
申请号：US11011483
申请日：2004-12-14
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： B29C41/08
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/821 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91583 , A61F2210/0076 , A61F2250/0039 , A61F2250/0068
摘要： A stent is made by providing a sacrificial template which defines a stent pattern. At least one layer of material is applied over at least a portion of the stent pattern of the sacrificial template. The sacrificial template is then eliminated.
摘要翻译：通过提供限定支架图案的牺牲模板来制造支架。在牺牲模板的支架图案的至少一部分上施加至少一层材料。然后消除牺牲模板。

48. 发明申请

US20060000812A1 Method and apparatus for controlling and adjusting the intensity profile of a laser beam employed in a laser welder for welding polymeric and metallic components 失效
标题翻译：用于控制和调节激光焊接机中用于焊接聚合物和金属部件的激光束的强度分布的方法和装置
公开(公告)号：US20060000812A1
公开(公告)日：2006-01-05
申请号：US10883868
申请日：2004-07-02
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： B23K26/00 , B32B37/00
CPC分类号： B29C65/1629 , B23K26/03 , B23K26/032 , B23K26/034 , B23K26/0643 , B23K26/073 , B29C65/1616 , B29C65/1619 , B29C65/1638 , B29C65/1654 , B29C65/1674 , B29C66/1142 , B29C66/301 , B29C66/43 , B29C66/5221 , B29C66/534 , B29C66/71 , B29C66/73116 , B29C66/73132 , B29C66/73921 , B29C66/742 , B29C66/836 , B29C66/91216 , B29C66/91221 , B29C66/91411 , B29C66/91443 , B29C66/91641 , B29C66/961 , B29C66/962 , B29K2023/065 , B29K2023/083 , B29K2027/18 , B29K2067/00 , B29K2075/00 , B29K2305/12 , B29L2031/7542 , B29L2031/7543 , B29K2077/00 , B29K2071/00 , B29K2067/006 , B29K2067/003 , B29K2033/08 , B29K2025/04 , B29K2023/0633 , B29K2023/0625 , B29K2021/003
摘要： A method and apparatus is provided for forming a fusion bond between two materials such as two components of a catheter. The method begins by forming a bond site by positioning a portion of a first body with respect to a portion of a second body so that a fusion bond site is formed. A laser beam is generated that has an intensity profile across its width. The laser beam is directed onto at least a portion of the first and second bodies within the bond site so that a fusion zone having an increased temperature is formed. After the laser beam is generated, the intensity profile of the laser beam that is directed onto the bond site is controllably adjusted by an optical element such as a dynamically-adjustable beam shaping element
摘要翻译：提供了一种用于在诸如导管的两个部件的两种材料之间形成熔接的方法和装置。该方法开始于通过将第一主体的一部分相对于第二主体的一部分定位，从而形成熔合点位置来形成粘合部位。产生在其宽度上具有强度分布的激光束。激光束被引导到粘结位置内的第一和第二体的至少一部分上，从而形成具有升高的温度的熔融区。在产生激光束之后，通过诸如动态可调光束成形元件的光学元件可控地调节被引导到粘结部位上的激光束的强度分布

49. 发明申请

US20050234426A1 Catheter distal tip design and method of making 审中-公开
标题翻译：导管远端尖端设计及制作方法
公开(公告)号：US20050234426A1
公开(公告)日：2005-10-20
申请号：US10824996
申请日：2004-04-14
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： A61M25/00 , B23K26/40
CPC分类号： A61M25/0068 , A61M25/001 , A61M25/008 , A61M2025/0081 , A61M2025/1093 , B23K2103/42 , B23K2103/50
摘要： A catheter comprises a catheter shaft having a distal tip, the distal tip having an inner surface and an outer surface, the inner surface having a rounded profile. The catheter may be made by rounding the inner surface of the distal tip.
摘要翻译：导管包括具有远侧末端的导管轴，所述远侧末端具有内表面和外表面，所述内表面具有圆形轮廓。导管可以通过使远侧末端的内表面四舍五入而制成。

50. 发明申请

US20050154943A1 Mechanism for adjacent-symbol error correction and detection 有权
标题翻译：相邻符号纠错和检测机制
公开(公告)号：US20050154943A1
公开(公告)日：2005-07-14
申请号：US10747590
申请日：2003-12-29
申请人： James Alexander , Thomas Holman , Mark Heap , Stanley Kulick
发明人： James Alexander , Thomas Holman , Mark Heap , Stanley Kulick
IPC分类号： G11C29/00 , G11C29/42
CPC分类号： G11C29/42 , G11C11/401 , G11C2029/0409
摘要： According to one embodiment a computer system is disclosed. The computer system includes memory. The memory includes two or more rows, where each row has a plurality of memory devices. The computer system also includes a chipset. The chipset includes a detection/correction circuit to detect single and double symbol errors and correct single symbol errors for each memory row, and markers to maintain a log of errors within each memory row
摘要翻译：根据一个实施例，公开了一种计算机系统。计算机系统包括内存。存储器包括两行或更多行，其中每行具有多个存储器件。计算机系统还包括芯片组。该芯片组包括一个检测/校正电路，用于检测单个和双重符号错误并纠正每个存储器行的单个符号错误，以及标记以维护每个存储器行内的错误日志

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