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    • 41. 发明申请
    • Devices with Photocatalytic Surfaces and Uses Thereof
    • 具有光催化表面及其用途的设备
    • US20080039770A1
    • 2008-02-14
    • US11836841
    • 2007-08-10
    • Richard FrancisCarl Schu
    • Richard FrancisCarl Schu
    • A61M37/00
    • A61L29/106A61L27/306A61L27/50A61L29/14A61L31/088A61L31/14A61N5/0624A61N2005/0651A61N2005/0659A61N2005/0661
    • The present invention is directed to a device, such as a medical device, comprising at least one photocatalytic layer and at least one source of electromagnetic radiation, such as an LED or an electroluminescent material and methods of use. In some embodiments, the device includes an electrically conductive layer, such as an optically transparent conductive oxide, that is adapted to be biased from a voltage source. A method for increasing the energy efficiency of a photocatalytic surface comprises electrically biasing a transparent conductive oxide layer. A method for illuminating a complex three-dimensional surface comprises illuminating a photocatalytic layer with electromagnetic radiation from an electroluminescent layer. The devices and methods of the invention are useful, for example, for removing or preventing the formation of organic matter on a sensor window.
    • 本发明涉及一种包括至少一种光催化层和至少一种电磁辐射源(诸如LED或电致发光材料)及其使用方法的装置,例如医疗装置。 在一些实施例中,该器件包括适于从电压源偏置的导电层,例如光学透明导电氧化物。 提高光催化表面的能量效率的方法包括电偏置透明导电氧化物层。 用于照明复杂三维表面的方法包括用电致发光层的电磁辐射照射光催化层。 本发明的装置和方法例如用于去除或防止在传感器窗口上形成有机物质是有用的。
    • 42. 发明申请
    • Medical Device Having Coating With Zeolite Drug Reservoirs
    • 具有沸石药物储库涂层的医疗器械
    • US20070259017A1
    • 2007-11-08
    • US11381823
    • 2006-05-05
    • Richard Francis
    • Richard Francis
    • A61K33/06A61F2/02
    • A61L31/10A61L31/146A61L31/16A61L2300/602A61L2300/606A61L2420/04
    • A medical device having a drug-eluting coating that includes a pharmaceutical compound or, more generally, a therapeutic material housed within pores of a zeolite carrier. The zeolite carrier has an open porous structure with reservoirs for holding the therapeutic material. The therapeutic material loaded zeolites may be suspended or dispersed within a bioerodible polymer matrix to provide controlled delivery of the therapeutic material. Zeolite drug carriers may have enhanced or optimally engineered pore sizes for a particular therapeutic material and release profile. Along with a therapeutic material, reservoirs of a zeolite drug delivery system may include a release agent. The release agent may be used to entrap the therapeutic material until such time as a triggering condition is met that prompts the release agent to activate and thereby release the therapeutic material from the zeolite reservoir.
    • 一种具有药物洗脱涂层的医疗装置,其包括药物化合物或更一般地,容纳在沸石载体的孔内的治疗材料。 沸石载体具有开放的多孔结构,其具有用于保持治疗材料的储存器。 负载治疗材料的沸石可以悬浮或分散在生物可腐蚀的聚合物基质中以提供治疗材料的受控递送。 沸石药物载体可以具有用于特定治疗材料和释放曲线的增强或最佳设计的孔径。 与治疗材料一起,沸石药物递送系统的储存器可以包括脱模剂。 释放剂可以用于捕获治疗材料,直到达到触发条件的时间,促使脱模剂活化,从而从沸石储存器释放治疗材料。
    • 43. 发明申请
    • Stent Foundation for Placement of a Stented Valve
    • 用于放置阀的支架基础
    • US20070244546A1
    • 2007-10-18
    • US11379105
    • 2006-04-18
    • Richard Francis
    • Richard Francis
    • A61F2/24A61F2/90
    • A61F2/2412A61F2/2418A61F2/2433A61F2/2436A61F2/2475A61F2250/0063
    • A valve replacement system that can be used for treating abnormalities of the right ventricular outflow tract in a nonsymmetrical region of a vessel or conduit that includes a prosthetic valve device and a foundation structure. The foundation structure contacts a portion of the inner wall of a vessel or conduit, and undergoes a shape change resulting in a corresponding change in the wall of the vessel or conduit. As a result, the lumen of the conduit is made symmetrical, and is complementary to the exterior surface of the stented valve, and thereby, improves the functioning of the valve. Another embodiment of the invention includes a method for replacing a pulmonary valve that includes forming a symmetrical region in a lumen of a conduit and placing a stented valve in the symmetrical region.
    • 一种瓣膜置换系统,其可用于治疗包括假体瓣膜装置和基础结构的血管或导管的非对称区域中右心室流出道的异常。 基础结构接触容器或管道的内壁的一部分,并经历形状变化,导致容器或导管壁的相应变化。 结果,导管的管腔是对称的,并且与支架瓣膜的外表面互补,从而改善了阀的功能。 本发明的另一个实施例包括一种用于替换肺动脉瓣的方法,该肺动脉瓣包括在导管的内腔中形成对称区域并将支架瓣膜置于对称区域。