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41. 发明授权

US08556862B2 Needle mounting feature for ensuring proper reconstitution sequence 有权
标题翻译：针安装功能，确保正确的重建顺序
公开(公告)号：US08556862B2
公开(公告)日：2013-10-15
申请号：US13119200
申请日：2009-09-18
申请人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Matthew D. Sweeney , Lionel Vedrine
发明人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Matthew D. Sweeney , Lionel Vedrine
IPC分类号： A61M5/32
CPC分类号： A61M5/2448 , A61M5/2066 , A61M5/3129 , A61M5/3134 , A61M5/3243 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2496 , A61M2005/3104
摘要： A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no needle mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered.
摘要翻译：本发明提供了一种具有可相对于身体移动的主体和针安装表面的医疗注射器，针安装表面具有用于将针安装到其上的特征。在初始状态下，针安装表面设置在主体内，没有针安装在其上。通过主体和针安装表面之间的相对移动，针安装表面被推出身体。有利地，提供了一种医疗注射器，其确保在制备装置时的适当顺序，特别是关于在制备要施用的药物之后允许将医用针安装到装置的步骤。

42. 发明授权

US08512287B2 Patch-like infusion device 有权
标题翻译：贴片式输液装置
公开(公告)号：US08512287B2
公开(公告)日：2013-08-20
申请号：US10916649
申请日：2004-08-12
申请人： Chris N. Cindrich , Ralph L. Sonderegger , Glade Howell , Weston F. Harding , Alexander G. Lastovich , Lionel Vedrine
发明人： Chris N. Cindrich , Ralph L. Sonderegger , Glade Howell , Weston F. Harding , Alexander G. Lastovich , Lionel Vedrine
IPC分类号： A61M5/20
CPC分类号： A61M5/158 , A61M5/14248 , A61M5/145 , A61M5/16804 , A61M2005/14256 , A61M2005/1426 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2209/06
摘要： A system and method for a patch-like, self-contained substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir, wherein the device can be attached to a skin surface via an adhesive contact surface and a push button activation assembly can then be used to remove an interlock, allowing a disk, or Belleville spring assembly to apply an essentially even and constant pressure to the contents of the fluid reservoir, allow the release of the patient needles into the skin surface, and establish a fluid communication path between the patient needles and the pressurized fluid reservoir contents. The push button activation assembly further allows the release of one or more improved safety mechanisms after use.
摘要翻译：一种用于贴片状独立物质输注装置的系统和方法，其提供一个或多个基本上隐藏的患者针，所述患者针可以与流体储存器流体连通，其中所述装置可以通过粘合剂附着到皮肤表面接触表面和按钮激活组件然后可以用于去除互锁，允许盘或贝氏弹簧组件对流体储存器的内容物施加基本均匀且恒定的压力，允许将患者针头释放到皮肤表面，并且在患者针和加压流体储存器内容物之间建立流体连通路径。按钮激活组件还允许在使用之后释放一个或多个改进的安全机构。

43. 发明授权

US08500682B2 Medical injector with post-autoreconstitution dose setting and autoplunger drive 有权
标题翻译：医用注射器具有后自动重新配置剂量设置和自动驱动
公开(公告)号：US08500682B2
公开(公告)日：2013-08-06
申请号：US13119266
申请日：2009-09-18
申请人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Lionel Vedrine
发明人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Lionel Vedrine
IPC分类号： A61M37/00 , A61M5/20
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156
摘要： A medical injector is provided herein having a body; a reservoir containing first and second mixable component; a stopper; a plunger; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance so that the stopper traverses at least a predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation being activated by separate triggers.
摘要翻译：本发明提供一种具有身体的医用注射器; 包含第一和第二可混合组分的储存器; 塞子柱塞设置成使柱塞前进的弹簧; 第一可释放保持器，用于将柱塞可释放地保持在第一状态，抵抗弹簧的力; 用于使第一可释放保持器释放柱塞的第一触发器; 第二可释放保持器，用于将所述柱塞可释放地保持在抵抗所述弹簧的力的第二状态; 以及用于使第二可释放保持器释放柱塞的第二触发器。弹簧使柱塞前进，使得止动件至少延伸一定程度的前进，从而引起第一和第二可混合部件的混合。有利地，对于本发明，提供了一种医疗注射器，其允许自动重新配置，随后的剂量设定和自动活动激活由单独的触发器激活。

44. 发明申请

US20120209171A1 CARTRIDGE FOR POWDER AND LIQUID DRUG 有权
标题翻译：粉剂和液体药盒
公开(公告)号：US20120209171A1
公开(公告)日：2012-08-16
申请号：US12679508
申请日：2008-09-29
申请人： Lionel Vedrine , Roger W. Groskopf , Matthew Sweeney , Talpade A. Dnyanesh , Min Wei , Ruane Jeter
发明人： Lionel Vedrine , Roger W. Groskopf , Matthew Sweeney , Talpade A. Dnyanesh , Min Wei , Ruane Jeter
IPC分类号： A61J1/20 , A61M5/31
CPC分类号： A61M5/284 , A61M5/2448 , A61M5/288 , A61M5/3134 , A61M5/31513 , A61M5/345 , A61M5/347 , A61M5/348 , A61M2005/3104 , A61M2005/31516 , B65B3/003
摘要： A cartridge or injector for holding and mixing a medical product is provided herein including a tubular body having a cylindrical wall having first and second opposing ends. The wall includes inner and outer surfaces with the inner surface having a generally constant cross-section along at least a drug mixing area. A first stopper is slidably disposed within the wall between the first and second ends, the first stopper defining a liquid-tight seal with the inner surface. A second stopper is slidably disposed within the wall between the first stopper and the first end, the second stopper defining a liquid-tight seal with the inner surface. A flexible insert is disposed at or in proximity to the second end, the insert forming a liquid-tight seal with the wall, the insert being pierceable by a medical needle or other piercing instrument. A rigid retainer is fixed to the wall having an opening therein for providing access to the insert for piercing by a medical needle. The insert extends into the retainer and forms a liquid-tight seal across the opening. Advantageously, with the subject invention, a reconstitution assembly may be provided which has a sufficiently large distal opening during assembly which allows a dry component to be introduced into the device in a dry state.
摘要翻译：本文提供了用于保持和混合医疗产品的药筒或注射器，其包括具有圆柱形壁的管状体，其具有第一和第二相对端。该壁包括内表面和外表面，其中内表面至少沿着药物混合区域具有大致恒定的横截面。第一止动件可滑动地设置在第一和第二端之间的壁内，第一止动件限定与内表面的液密密封。第二止动件可滑动地设置在第一止挡件和第一端之间的壁内，第二止动件限定与内表面的液密密封。柔性插入件设置在第二端处或附近，插入件与壁形成液密密封，插入件可被医用针或其它穿刺器械刺穿。刚性保持器固定到其上具有开口的壁上，用于提供通过医用针穿刺插入物的通路。插入件延伸到保持器中并且跨越开口形成液密密封。有利地，对于本发明，可以提供在组装期间具有足够大的远端开口的重构组件，其允许在干燥状态下将干燥部件引入装置。

45. 发明授权

US08137313B2 Device for injection of a product, in particular for medical use 有权
标题翻译：用于注射产品的装置，特别是用于医疗用途的装置
公开(公告)号：US08137313B2
公开(公告)日：2012-03-20
申请号：US10573226
申请日：2004-09-14
申请人： Lionel Vedrine
发明人： Lionel Vedrine
IPC分类号： A61M5/20
CPC分类号： A61M5/2429 , A61M5/2033 , A61M5/2459 , A61M5/326 , A61M2005/3263
摘要： A medical device for the injection of a product. The device includes a body receiving an injection needle and a container containing the product to be injected; an arrangement for holding the needle in an injection position; an arrangement for holding the container in a position permitting injection; and, a piston engaged in the container. The device also includes first and second actuators which make it possible, at the end of the injection, to respectively release the arrangement for holding the needle before, or simultaneously to, the release of the arrangement for holding the container. A container support is mounted slidably on the body and is displaceable relative to the latter in order to perform the injection. The container support is held in a standby position before injection with the needle being held in the injection position.
摘要翻译：用于注射产品的医疗设备。该装置包括接收注射针的主体和容纳待注射的产品的容器; 用于将针保持在注射位置的布置; 用于将容器保持在允许注射的位置的布置; 以及接合在容器中的活塞。该装置还包括第一和第二致动器，其使得在注射结束时可以分别释放用于保持针头的装置，或同时释放用于保持容器的装置。容器支撑件可滑动地安装在主体上，并且可相对于主体移动以执行注射。在注射之前，容器支撑件保持在待机位置，其中针被保持在注射位置。

46. 发明申请

US20110213315A1 MEDICAL INJECTOR WITH SLIDABLE SLEEVE ACTIVATION 有权
标题翻译：医疗注射器与滑动套管激活
公开(公告)号：US20110213315A1
公开(公告)日：2011-09-01
申请号：US13063792
申请日：2009-09-18
申请人： Matthew D. Sweeney , Richard A. Cronenberg , Lionel Vedrine
发明人： Matthew D. Sweeney , Richard A. Cronenberg , Lionel Vedrine
IPC分类号： A61M5/315
CPC分类号： A61M5/2448 , A61M5/2033 , A61M5/3146 , A61M5/31553 , A61M5/3156 , A61M2005/2073 , A61M2005/2451
摘要： In one aspect, a medical injector is provided herein which includes a body; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; a releasable retainer for retaining the plunger in a first state against force of the spring; and, a sleeve disposed on the body, the sleeve being slidable relative to the body. Sliding movement of the sleeve over a predetermined extent relative to the body results in the releasable retainer releasing the plunger thereby allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon sliding movement of the sleeve, thereby minimizing premature or failed activations.
摘要翻译：在一个方面，本文提供了一种医用注射器，其包括主体; 设置在本体中的可移位柱塞; 设置成使柱塞前进的弹簧; 可释放的保持器，用于将柱塞保持在第一状态以抵抗弹簧的力; 以及设置在所述主体上的套筒，所述套筒可相对于所述主体滑动。套筒相对于主体的预定范围的滑动使得可释放的保持器释放柱塞，从而允许弹簧推进柱塞。有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在套筒的滑动运动时触发，从而最小化过早或失效的激活。

47. 发明申请

US20110049265A1 Sprayer, In Particular For Medical Use 有权
标题翻译：喷雾器，特别用于医疗用途
公开(公告)号：US20110049265A1
公开(公告)日：2011-03-03
申请号：US12867920
申请日：2009-02-02
申请人： Lionel Vedrine
发明人： Lionel Vedrine
IPC分类号： B05B11/00 , B23P19/02
CPC分类号： A61M11/00 , A61M11/007 , A61M15/0025 , B05B11/0027 , B65D41/3409 , Y10T29/49945
摘要： This sprayer (1) includes a container (2) of product to be sprayed, provided with a delivery opening for this product, and a spraying assembly (3), said spraying assembly (3) being in fluid communication with this delivery opening and being securable onto this container (2) by insertion about a mounting axis, this spraying assembly (3) including a sprayer body (6) delimiting a proximalarea (14) conformed so as to be securable to said container (2), and including a distal wall (10), transverse to said mounting axis, in which a spraying aperture (11) is arranged, and a cap (7) intended to be mounted on the sprayer body (6). According to the invention, the cap (7) includes a wall (20) transverse to said mounting axis, being sufficiently rigid so as to bear without substantial damaging a force from 50 to 100 N necessary to secure this sprayer body (6) to said container (2) and thus to enable the transmission to said sprayer body (6) of this force.
摘要翻译：该喷雾器（1）包括一个待喷射产品的容器（2），该容器（2）具有用于该产品的输送开口和一个喷射组件（3），所述喷射组件（3）与该输送口流体连通，该喷射组件（3）包括限定近端区域（14）的喷雾器本体（6），所述喷嘴主体（6）适于安装在所述容器（2）上，并且包括远端横向于所述安装轴线的壁（10），其中布置有喷射孔（11），以及旨在安装在喷雾器主体（6）上的盖（7）。根据本发明，盖（7）包括横向于所述安装轴线的壁（20），其具有足够的刚性，以便承受不会将该喷雾器本体（6）固定到所述安装轴上所需的50至100N的力容器（2），从而能够向该喷雾器主体（6）传递该力。

48. 发明申请

US20090292257A1 Safety Shield System for Prefilled Syringe 有权
标题翻译：预填注射器安全防护系统
公开(公告)号：US20090292257A1
公开(公告)日：2009-11-26
申请号：US12534186
申请日：2009-08-03
申请人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
发明人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
IPC分类号： A61M5/32
CPC分类号： A61M5/326 , A61M2005/3247 , A61M2005/3261
摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.
摘要翻译：提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。弹簧弹性地将护罩从缩回位置推向延伸位置。止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。注射器可滑动地联接到保持器，并且在护罩内延伸。注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。在保持器上设置有用于将护罩保持在延伸位置的凹处。

49. 发明授权

US07455661B2 Safety shield system for prefilled syringe 有权
标题翻译：预填充注射器的安全防护系统
公开(公告)号：US07455661B2
公开(公告)日：2008-11-25
申请号：US10737627
申请日：2003-12-16
申请人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
发明人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
IPC分类号： A61M5/00
CPC分类号： A61M5/326 , A61M2005/3247 , A61M2005/3261
摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.
摘要翻译：提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。弹簧弹性地将护罩从缩回位置推向延伸位置。止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。注射器可滑动地联接到保持器，并且在护罩内延伸。注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。在保持器上设置有用于将护罩保持在延伸位置的凹处。

50. 发明申请

US20080183137A1 Safety Shield System for Prefilled Syringe 有权
标题翻译：预填注射器安全防护系统
公开(公告)号：US20080183137A1
公开(公告)日：2008-07-31
申请号：US12098770
申请日：2008-04-07
申请人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
发明人： Laurent Barrelle , Lionel Vedrine , Paul G. Alchas
IPC分类号： A61M5/32
CPC分类号： A61M5/326 , A61M2005/3247 , A61M2005/3261
摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.
摘要翻译：提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。弹簧弹性地将护罩从缩回位置推向延伸位置。止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。注射器可滑动地联接到保持器，并且在护罩内延伸。注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。在保持器上设置有用于将护罩保持在延伸位置的凹处。

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