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41. 发明申请

US20070213696A1 Photocosmetic device 审中-公开
标题翻译：光学装置
公开(公告)号：US20070213696A1
公开(公告)日：2007-09-13
申请号：US11415362
申请日：2006-05-01
申请人： Gregory Altshuler , Ilya Yaroslavsky , James Cho , Stewart Wilson , Liam O'Shea , Andrey Belikov
发明人： Gregory Altshuler , Ilya Yaroslavsky , James Cho , Stewart Wilson , Liam O'Shea , Andrey Belikov
IPC分类号： A61B18/18 , A61N5/06
CPC分类号： A61N5/0616 , A46B5/0095 , A46B15/0036 , A46B2200/1066 , A61B18/20 , A61B18/203 , A61B2018/00023 , A61B2018/00452 , A61B2018/00904 , A61B2018/2065 , A61B2018/207 , A61B2090/065 , A61N2005/0644 , A61N2005/0651 , A61N2005/0652 , A61N2005/0662 , A61N2005/067
摘要： An apparatus is disclosed for use by a consumer in a non-medical setting that uses at least one low power optical radiation source in a suitable device that can be positioned over a treatment area for a substantial period of time or can be moved over the treatment area one or more times during each treatment. The apparatus can be moved over or applied to or near the consumer's skin surface as light or other electromagnetic radiation is applied to the skin.
摘要翻译：公开了一种用于非医疗环境中的消费者使用的装置，其在合适的装置中使用至少一个低功率光辐射源，该装置可以在治疗区域上定位相当长的一段时间，或者可以在治疗每次治疗期间一次或多次。当将光或其它电磁辐射施加到皮肤上时，该装置可以移动或施加到消费者的皮肤表面或附近。

42. 发明申请

US20070198004A1 PHOTOCOSMETIC DEVICE 审中-公开
标题翻译：光电设备
公开(公告)号：US20070198004A1
公开(公告)日：2007-08-23
申请号：US11682645
申请日：2007-03-06
申请人： Gregory Altshuler , Ilya Yaroslavsky , James Cho , Stewart Wilson , Andrey Belikov , Liam O'Shea
发明人： Gregory Altshuler , Ilya Yaroslavsky , James Cho , Stewart Wilson , Andrey Belikov , Liam O'Shea
IPC分类号： A61B18/18 , A61F2/00
CPC分类号： A61N5/0616 , A46B5/0095 , A46B15/0036 , A46B2200/1066 , A61B18/20 , A61B18/203 , A61B2018/00023 , A61B2018/00452 , A61B2018/00904 , A61B2018/2065 , A61B2018/207 , A61B2090/065 , A61N2005/0644 , A61N2005/0651 , A61N2005/0652 , A61N2005/0662 , A61N2005/067
摘要： An apparatus is disclosed for use by a consumer in a non-medical setting that uses at least one low power electromagnetic radiation source in a suitable device that can be positioned over a treatment area for a substantial period of time or can be moved over the treatment area one or more times during each treatment. The apparatus can be moved over or applied to or near the consumer's skin surface as light or other electromagnetic radiation is applied to the skin. The apparatus contains a control system that controls the radiation source, which may include various sections that are controlled independently.
摘要翻译：公开了一种在非医疗设置中使用消费者的装置，其在合适的装置中使用至少一个低功率电磁辐射源，该装置可以在治疗区域上定位相当长的一段时间，或者可以在治疗每次治疗期间一次或多次。当将光或其它电磁辐射施加到皮肤上时，该装置可以移动或施加到消费者的皮肤表面或附近。该装置包含控制辐射源的控制系统，其可以包括独立控制的各种部分。

43. 发明申请

US20070060819A1 Skin optical characterization device 失效
标题翻译：皮肤光学表征装置
公开(公告)号：US20070060819A1
公开(公告)日：2007-03-15
申请号：US11522124
申请日：2006-09-15
申请人： Gregory Altshuler , Guangming Wang , Henry Zenzie
发明人： Gregory Altshuler , Guangming Wang , Henry Zenzie
IPC分类号： A61B6/00 , A61B5/00
CPC分类号： A61B5/0082 , A61B5/0059 , A61B5/443 , A61B5/444 , A61B5/445 , A61B5/6843
摘要： The present invention is generally directed to dermatological devices and methods in which one or more skin characteristics, such as the melanin index, are determined by analyzing radiation backscattered from a skin region illuminated by at least one, and preferably, two or more wavelengths, e.g., in a range of about 600 nm to about 900 nm. In many embodiments, the radiation is coupled to the skin via a waveguide, and an optical sensor is employed to ascertain contact between the waveguide (e.g., a waveguide surface adapted for contact with the skin) and the skin.
摘要翻译：本发明一般涉及皮肤病学装置和方法，其中通过分析由至少一个，优选地，两个或更多个波长照射的皮肤区域反向散射的辐射来确定一种或多种皮肤特征，例如黑色素指数，例如在约600nm至约900nm的范围内。在许多实施例中，辐射通过波导耦合到皮肤，并且使用光学传感器来确定波导（例如，适于与皮肤接触的波导表面）和皮肤之间的接触。

44. 发明申请

US20070049910A1 Eye-safe photocosmetic device 审中-公开
标题翻译：眼睛安全的光敏装置
公开(公告)号：US20070049910A1
公开(公告)日：2007-03-01
申请号：US11500588
申请日：2006-08-08
申请人： Gregory Altshuler , Henry Zenzie , Christopher Gaal , Robert Lopez , Guangming Wang
发明人： Gregory Altshuler , Henry Zenzie , Christopher Gaal , Robert Lopez , Guangming Wang
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B90/04 , A61B2017/00057 , A61B2017/308 , A61B2018/00005 , A61B2018/00452 , A61B2018/00458 , A61B2018/00476 , A61B2090/065
摘要： Devices and methods for treating tissue with radiation, including light and other optical radiation, in a manner that is eye-safe are described. In one embodiment, a photocosmetic treatment device has a cavity into which tissue to be treated is drawn. The device determines whether the tissue is safe to treat and whether the tissue may be tissue associated with the eyes, such as an eyelid. In another embodiment, an eye-safe pulse of radiation is provided at a time interval prior to treatment of the tissue. The pulse is at a wavelength of radiation that the human eye perceives as particularly intense and uncomfortable, even though the pulse is not dangerous or destructive. If the device is oriented to treat eye tissue, directly or through the eyelid, the pulse will cause an aversive reaction in the subject being treated that inhibits the treatment.
摘要翻译：描述了以眼睛安全的方式处理包括光和其他光辐射的辐射的组织的装置和方法。在一个实施方案中，光敏化妆品处理装置具有被拉伸组织的空腔。该装置确定组织是否安全地治疗以及组织是否可能是与眼睛相关的组织，例如眼睑。在另一个实施例中，在处理组织之前的时间间隔提供辐射的眼睛安全脉冲。脉冲处于辐射波长，即使脉搏不危险或具有破坏性，人眼也会感觉到特别强烈和不舒服。如果该装置被定向以直接或通过眼睑治疗眼组织，则脉冲将导致被治疗受试者抑制治疗的反应。

45. 发明申请

US20060253176A1 Dermatological treatment device with deflector optic 审中-公开
标题翻译：带导向器光学的皮肤病治疗装置
公开(公告)号：US20060253176A1
公开(公告)日：2006-11-09
申请号：US11357749
申请日：2006-02-17
申请人： Joseph Caruso , Gregory Altshuler , Liam O'Shea
发明人： Joseph Caruso , Gregory Altshuler , Liam O'Shea
IPC分类号： A61N5/06
CPC分类号： A61B18/203 , A61B18/20 , A61B90/36 , A61B2018/00452 , A61B2018/00904 , A61B2018/20359 , A61N2005/0629
摘要： This invention relates generally to methods and apparatus for utilizing energy, e.g., optical radiation, to treat various dermatological and cosmetic conditions. A handheld dermatological device that facilitates viewing and measuring parameters of a treatment area before, during, and after application of a treatment modality, and methods of use therefor, are disclosed. The device can include a deflective device that can steer radiation to control a target position of the radiation. The device can also include a control device to allow a user to control the radiation through manipulation of the deflective device.
摘要翻译：本发明一般涉及利用能量（例如光辐射）来治疗各种皮肤病学和美容条件的方法和装置。公开了一种便于在施用治疗方式之前，期间和之后观察和测量治疗区域的参数及其使用方法的手持式皮肤病学装置。该装置可以包括可以引导辐射以控制辐射的目标位置的偏转装置。该装置还可以包括控制装置，以允许用户通过操纵偏转装置来控制辐射。

46. 发明申请

US20060161143A1 Light energy delivery head 失效
公开(公告)号：US20060161143A1
公开(公告)日：2006-07-20
申请号：US11301340
申请日：2005-12-12
申请人： Gregory Altshuler , Henry Zenzie
发明人： Gregory Altshuler , Henry Zenzie
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00452 , A61B2018/00458 , A61B2018/00476 , A61B2090/065 , A61N5/0617 , A61N2005/005 , A61N2005/007
摘要： A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is applying light energy. In another aspect, various retroreflection configurations are provided which optimize retroreflection of back-scattered light energy from the medium. The size of the aperture through which light energy is applied to the medium is also controlled so as to provide a desired amplification coefficient as a result of retroreflection.

47. 发明申请

US20060149343A1 Cooling system for a photocosmetic device 审中-公开
标题翻译：光学设备的冷却系统
公开(公告)号：US20060149343A1
公开(公告)日：2006-07-06
申请号：US11230231
申请日：2005-09-15
申请人： Gregory Altshuler , Joseph Caruso , Henry Zenzie , James Burke , Andrei Efrofeev
发明人： Gregory Altshuler , Joseph Caruso , Henry Zenzie , James Burke , Andrei Efrofeev
IPC分类号： A61N5/06
CPC分类号： A45D26/0061 , A45D44/005 , A61B18/203 , A61B2017/00026 , A61B2017/00747 , A61B2017/00765 , A61B2017/00769 , A61B2018/00011 , A61B2018/00029 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904 , A61B2090/065 , A61N1/328
摘要： Photocosmetic device for use in medical or non-medical environments (e.g., a home, barbershop, or spa), which can be used for a variety of tissue treatments. Radiation is delivered to the tissue via optical systems designed to pattern the radiation and project the radiation to a particular depth. The device has a variety of cooling systems including phase change cooling solids and liquids to cool treated skin and the radiation sources. Contact sensors and motion sensor may be used to enhance treatment. The device may be modular to facilitate manufacture and replacement of parts.
摘要翻译：用于医疗或非医疗环境（例如，家庭，理发店或温泉）的光学设备，其可用于各种组织处理。辐射通过设计成对辐射进行图案化并将辐射投射到特定深度的光学系统传送到组织。该装置具有各种冷却系统，包括相变冷却固体和液体以冷却经处理的皮肤和辐射源。接触传感器和运动传感器可用于增强治疗。该装置可以是模块化的，以便于部件的制造和更换。

48. 发明申请

US20050107849A1 Tissue penetrating oral phototherapy applicator 失效
标题翻译：组织穿透口腔光疗法
公开(公告)号：US20050107849A1
公开(公告)日：2005-05-19
申请号：US10776687
申请日：2004-02-10
申请人： Gregory Altshuler , Valery Tuchin
发明人： Gregory Altshuler , Valery Tuchin
IPC分类号： A46B15/00 , A61B17/00 , A61B18/00 , A61B18/20 , A61B19/00 , A61C1/08 , A61C19/06 , A61F7/00 , A61F7/10 , A61K8/02 , A61N5/00 , A61N5/06 , A61Q11/00
CPC分类号： A46B15/0002 , A46B15/0036 , A46B2200/1066 , A61B18/203 , A61B2017/00057 , A61B2017/00084 , A61B2018/00005 , A61B2018/00452 , A61B2090/065 , A61C1/081 , A61C1/088 , A61C17/3481 , A61C19/06 , A61F7/00 , A61F2007/0087 , A61F2007/0089 , A61F2007/0096 , A61F2007/0292 , A61F2007/108 , A61K8/02 , A61K2800/438 , A61K2800/81 , A61N5/0601 , A61N5/0603 , A61N5/0617 , A61N5/062 , A61N5/0624 , A61N2005/005 , A61N2005/0606 , A61N2005/0644 , A61N2005/0652 , A61N2005/0662 , A61Q11/00
摘要： Oral phototherapy applicators are disclosed that are sized and shaped so as to fit at least partially in a user's mouth and have at least one radiation emitter coupled to an apparatus body to irradiate a portion of the oral cavity with phototherapeutic radiation, the emitter being capable of delivering radiation to a region of facial tissue. The apparatus can be configured to direct radiation to at least one portion of the oral cavity, e.g., a tooth, cheek, tongue, palate, throat, lymphatic tissue, blood, gland, follicle, collagen and pigmentation. In one embodiment, radiation from the emitter can penetrate the muscosal lining of the oral cavity and deliver phototherapeutic energy to a region of facial tissue. The apparatus can further include bristles to provide a phototherapeutic toothbrush. Alternatively, the apparatus body can be adapted for placement in a fixed position relative to the oral cavity during phototherapy.
摘要翻译：公开了口腔光疗施用器，其尺寸和形状至少部分地配合在使用者的口中，并且具有耦合到装置主体的至少一个辐射发射器，以用光治疗辐射照射口腔的一部分，发射器能够将辐射传送到面部组织的区域。该装置可以被配置成将辐射引导到口腔的至少一部分，例如牙齿，脸颊，舌头，上颚，咽喉，淋巴组织，血液，腺体，卵泡，胶原和色素沉着。在一个实施例中，来自发射器的辐射可以穿透口腔的肌肉衬里并将光治疗能量递送到面部组织的区域。该装置还可以包括刷毛以提供光治疗牙刷。或者，装置主体可适于在光疗期间相对于口腔放置在固定位置。

49. 发明授权

US06508813B1 System for electromagnetic radiation dermatology and head for use therewith 有权
公开(公告)号：US06508813B1
公开(公告)日：2003-01-21
申请号：US09268433
申请日：1999-03-12
申请人： Gregory Altshuler
发明人： Gregory Altshuler
IPC分类号： A61B1818
CPC分类号： A61B18/203 , A61B18/22 , A61B2017/00057 , A61B2017/00084 , A61B2017/00106 , A61B2017/00752 , A61B2017/00756 , A61B2017/00769 , A61B2018/00005 , A61B2018/00023 , A61B2018/00041 , A61B2018/00452 , A61B2018/00458 , A61B2018/00476 , A61B2018/1807 , A61B2018/2261 , A61B2090/065 , A61N5/0617
摘要： A system for treating a selected dermatologic problem and a head for use with such system are provided. The head may include an optical waveguide having a first end to which EM radiation appropriate for treating the condition is applied. The waveguide also has a skin-contacting second end opposite the first end, a temperature sensor being located within a few millimeters, and preferably within 1 to 2 millimeters, of the second end of the waveguide. A temperature sensor may be similarly located in other skin contacting portions of the head. A mechanism is preferably also provided for removing heat from the waveguide and, for preferred embodiments, the second end of the head which is in contact with the skin has a reflection aperture which is substantially as great as the radiation back-scatter aperture from the patient's skin. Such aperture may be the aperture at the second end of the waveguide or a reflection plate or surface of appropriate size may surround the waveguide or other light path at its second end. The portion of the back-scattered radiation entering the waveguide is substantially internally reflected therein, with a reflector being provided, preferably at the first end of the waveguide, for returning back-scattered light to the patient's skin. The reflector may be angle dependent so as to more strongly reflect back scattered light more perpendicular to the skin surface than back scattered radiation more parallel to the skin surface. Controls are also provided responsive to the temperature sensing for determining temperature at a predetermined depth in the patient's skin, for example at the DE junction, and for utilizing this information to detect good thermal contact between the head and the patient's skin and to otherwise control treatment. The head may also have a mechanism for forming a reflecting chamber under the waveguide and drawing a fold of skin therein, or for providing a second enlarged waveguide to expand the optical aperture of the radiation.

50. 发明授权

US6080146A Method and apparatus for hair removal 失效
标题翻译：脱毛方法和装置
公开(公告)号：US6080146A
公开(公告)日：2000-06-27
申请号：US28416
申请日：1998-02-24
申请人： Gregory Altshuler , Michael Smotrich
发明人： Gregory Altshuler , Michael Smotrich
IPC分类号： A61B18/20 , A61B18/18
CPC分类号： A61B18/203 , A61B2018/00452 , A61B2018/00476
摘要： A method and apparatus for the removal of, and at least inhibiting the regrowth of, unwanted hair by applying optical radiation to the follicle, including the hair shaft therein, of an energy, a duration and wavelength to enhance the optical absorption characteristics of at least some component, (i.e., melanosomes, tissue, etc.) of the follicle without appreciably damaging skin outside the follicle; and subsequently applying optical radiation to the follicle of a wavelength which is more readily absorbed by the components of the follicle having optical absorption characteristics enhanced during step (a) then by unenhanced components and of an energy and duration to heat such enhanced components sufficiently to substantially destroy the follicle. For preferred embodiments, melanosomes in the bulb of the follicle, and in other portions of the follicle are heated by the initial optical radiation sufficiently to at least partially darken such melanosomes by browning or carbonization, and such darkening also occurs in tissue surrounding the melanosomes. While a single pulse may be utilized to perform this function, it is preferably performed by a succession of pulses, with each successive pulse darkening additional components of the follicle. For one embodiment, this process is repeated until sufficient components of the follicle have been darkened so that the next pulse results in the substantial destruction of the follicle. Alternatively, the radiation for the second step may be either of a specific wavelength or a broad-band radiation which is more readily absorbed by the enhanced components than by unenhanced components, and of an energy and duration which is sufficient to result in the destruction of the follicle. Other variations on the basic technique are also possible.
摘要翻译：一种用于通过向包括其中的毛发的毛囊施加光学辐射去除并且至少抑制不需要的毛发的再生长的能量，持续时间和波长以增强至少的光学吸收特性的方法和装置卵泡的一些组分（即，黑素体，组织等），而没有明显破坏卵泡外的皮肤; 并且随后将光辐射施加到波长的滤泡上，所述波长更容易被具有在步骤（a）期间增强的光吸收特征的滤泡组分吸收，然后通过未增强的组分和能量和持续时间来加热这些增强的组分，足以基本上破坏卵泡。对于优选的实施方案，卵泡的卵泡和卵泡的其它部分中的黑素体被初始的光学辐射充分加热，以通过褐变或碳化至少部分地使这些黑素体变暗，并且这种变暗也发生在黑素体周围的组织中。虽然可以使用单个脉冲来执行该功能，但是优选地通过一系列脉冲来执行，其中每个连续脉冲使毛囊的附加组分变暗。对于一个实施方案，重复该过程，直到卵泡的足够组分变暗，使得下一个脉冲导致卵泡的显着破坏。或者，用于第二步骤的辐射可以是特定波长或宽带辐射，其比增强的组分更容易被增强的组分吸收，并且能量和持续时间足以导致破坏卵泡。基本技术的其他变化也是可能的。

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