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41. 发明授权

US08172691B2 Boot 有权
标题翻译：启动
公开(公告)号：US08172691B2
公开(公告)日：2012-05-08
申请号：US12813631
申请日：2010-06-11
申请人： Markus Deisinger , Thomas Schmidt , Ralf Schumacher
发明人： Markus Deisinger , Thomas Schmidt , Ralf Schumacher
IPC分类号： F16D3/84
CPC分类号： F16J3/043 , F16D3/845
摘要： A boot is disclosed having a first attachment region which is assigned to a joint, and a second attachment region which is assigned to a shaft. The boot has a plurality of folds, including a first fold region with at least two folds with a diameter that decreases in the direction of the second attachment region and at least one revolving, separating element which is arranged in an annular fold root between two folds.
摘要翻译：公开了具有分配给接头的第一附接区域和被分配给轴的第二附接区域的靴子。靴子具有多个褶皱，包括具有至少两个折叠的第一折叠区域，其直径在第二附接区域的方向上减小;以及至少一个旋转的分离元件，其设置在两个折叠之间的环形折叠根部。

42. 发明授权

US08157661B2 Bellows comprising a receiver for a retaining ring and method for producing the same 有权
标题翻译：波纹管包括用于保持环的接收器及其制造方法
公开(公告)号：US08157661B2
公开(公告)日：2012-04-17
申请号：US12443669
申请日：2006-09-29
申请人： Thorsten Scholtz , Markus Deisinger , Ralf Schumacher
发明人： Thorsten Scholtz , Markus Deisinger , Ralf Schumacher
IPC分类号： F16D3/84 , B29C49/00
CPC分类号： F16J3/042 , F16D3/2055 , F16D3/845 , Y10T403/31 , Y10T403/315
摘要： A bellows for a joint arrangement may include pleats, an axis and a joint end, a zone of the joint end being produced by blow molding and forming a receiver for a retaining ring. The receiver, in the proximity of the pleats, has a plurality of outward-pointing bulged portions that form a recess and at least one inclined receiving edge.
摘要翻译：用于接合装置的波纹管可以包括褶皱，轴线和接合端，通过吹塑成型并形成用于保持环的接收器来产生接合端的区域。接收器在褶皱附近具有多个向外指向的凸出部分，其形成凹部和至少一个倾斜的接收边缘。

43. 发明授权

US07846724B2 Method for selecting CHO cell for production of glycosylated antibodies 有权
标题翻译：用于选择用于产生糖基化抗体的CHO细胞的方法
公开(公告)号：US07846724B2
公开(公告)日：2010-12-07
申请号：US11732974
申请日：2007-04-05
申请人： Silke Hansen , Klaus-Peter Kuenkele , Dietmar Reusch , Ralf Schumacher
发明人： Silke Hansen , Klaus-Peter Kuenkele , Dietmar Reusch , Ralf Schumacher
IPC分类号： C12N5/06
CPC分类号： C07K16/2863 , C07K16/00 , C07K2317/41 , C07K2317/52
摘要： The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.
摘要翻译：本发明提供一种抗体，其包含在Asn297处用糖链糖基化的人IgG1或IgG3重链恒定结构域，所述抗体的特征在于所述糖链内的岩藻糖的量为至少99％，另外还含有 NGNA为1％以下，和/或N-末端α1,3半乳糖的量为1％以下，及其用途。

44. 外观设计

USD613246S1 Connector 有权
公开(公告)号：USD613246S1
公开(公告)日：2010-04-06
申请号：US29311021
申请日：2008-12-09
申请人： Michaela Muecke , Ralf Schumacher , Andreas Muhs , Simon Seereiner , Barbara Weithaas
设计人： Michaela Muecke , Ralf Schumacher , Andreas Muhs , Simon Seereiner , Barbara Weithaas

45. 发明授权

US07348165B2 Methods for detecting cancer cells by using nucleic acid encoding for IGF-1 receptor interacting proteins 失效
标题翻译：通过使用编码IGF-1受体相互作用蛋白的核酸检测癌细胞的方法
公开(公告)号：US07348165B2
公开(公告)日：2008-03-25
申请号：US10843747
申请日：2004-05-12
申请人： Tanja Ligensa , Ralf Schumacher , Michael Weidner
发明人： Tanja Ligensa , Ralf Schumacher , Michael Weidner
IPC分类号： C07H21/04 , C07H21/02 , C12P19/34
CPC分类号： C07K14/4702
摘要： The invention relates generally to a method for the detection of the proliferation of a tumor cell and more specifically wherein said method comprises nucleic acids (SEQ ID NO:1) encoding IIP-1.
摘要翻译：本发明一般涉及用于检测肿瘤细胞增殖的方法，更具体地说，其中所述方法包括编码IIP-1的核酸（SEQ ID NO：1）。

46. 发明授权

US07202058B2 IGF-1 receptor interacting proteins 失效
标题翻译： IGF-1受体相互作用蛋白
公开(公告)号：US07202058B2
公开(公告)日：2007-04-10
申请号：US10867039
申请日：2004-06-14
申请人： Tanja Ligensa , Ralf Schumacher , Michael Weidner
发明人： Tanja Ligensa , Ralf Schumacher , Michael Weidner
IPC分类号： G01N33/53 , C07K1/00
CPC分类号： C07K14/4702 , A61K38/1709
摘要： The invention comprises a method of screening compound(s) that inhibit the interaction between IGF-1R and IIP-10.
摘要翻译：本发明包括筛选抑制IGF-1R和IIP-10之间相互作用的化合物的方法。

47. 发明授权

US07097743B2 Method for operating a coke-oven battery 有权
标题翻译：操作焦炉电池的方法
公开(公告)号：US07097743B2
公开(公告)日：2006-08-29
申请号：US10469902
申请日：2002-03-23
申请人： Frank Krebber , Helmut Dobert , Ralf Schumacher , Ulrich Kochanski
发明人： Frank Krebber , Helmut Dobert , Ralf Schumacher , Ulrich Kochanski
IPC分类号： C10B27/06 , C10B47/00
CPC分类号： C10B27/06 , Y10T137/0396
摘要： A method is provided for operating a coke oven battery including many identical coking chambers, a raw gas receiver, and throttle devices arranged in the receiver for individually controlling the gas pressure in the chambers. Each throttle device includes an immersion bucket acted upon by water. Gas lines terminating in immersion pipes in the immersion buckets connect the chambers with the receiver. Throttle devices are employed that include an overflow that can be vertically adjusted by an actuating drive for controlling the liquid level in the immersion bucket. For a coking chamber to which a pressure control device is allotted, the setting signals for the actuating drive allocated to the time pressure curve in the process of carbonizing coal to coke are recorded as a position-time curve. The actuating drives of throttle devices that are allocated to coking chambers without pressure control devices are controlled according to the position-time curve.
摘要翻译：提供了一种操作焦炉电池的方法，该焦炉电池包括许多相同的焦化室，原始气体接收器和布置在接收器中的节气门装置，用于单独地控制室中的气体压力。每个节流装置包括由水作用的浸入式桶。在浸入桶中的浸入管中终止的气体管线将腔室与接收器连接。使用节流装置，其包括可以通过致动驱动器垂直调节的溢流，以控制浸入式铲斗中的液位。对于分配有压力控制装置的焦化室，记录分配给煤焦化过程中的时间压力曲线的致动驱动装置的设定信号作为位置 - 时间曲线。根据位置时间曲线控制分配给没有压力控制装置的焦化室的节流装置的致动驱动。

48. 发明申请

US20050118169A1 Antibodies against interleukin-1 receptor and uses thereof 审中-公开
标题翻译：抗白细胞介素-1受体的抗体及其用途
公开(公告)号：US20050118169A1
公开(公告)日：2005-06-02
申请号：US10937596
申请日：2004-09-09
申请人： Ilse Bartke , Francis Carr , Richard Chizzonite , Elsie Eugui , Georg Fertig , Anita Hamilton , Martin Lanzendoerfer , Petra Rueger , Ralf Schumacher , Theresa Truitt
发明人： Ilse Bartke , Francis Carr , Richard Chizzonite , Elsie Eugui , Georg Fertig , Anita Hamilton , Martin Lanzendoerfer , Petra Rueger , Ralf Schumacher , Theresa Truitt
IPC分类号： A61K39/395 , C07H21/04 , C07K16/28 , C12N5/06 , C12N15/13
CPC分类号： C07K16/2866 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to antibodies against interleukin-1 receptor (IL-1R), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. The antibodies of the present invention are particularly useful for treating a variety of inflammatory diseases including, but not limited to, rheumatoid arthritis.
摘要翻译：本发明涉及抗白细胞介素-1受体（IL-1R）的抗体，其制备方法，含有所述抗体的药物组合物及其用途。本发明的抗体特别可用于治疗各种炎性疾病，包括但不限于类风湿性关节炎。

49. 发明授权

US4348258A Spray nozzle for coke oven gas-collecting system 失效
标题翻译：焦炉煤气收集系统喷嘴
公开(公告)号：US4348258A
公开(公告)日：1982-09-07
申请号：US174451
申请日：1980-08-01
申请人： Carl-Heinz Struck , Ralf Schumacher
发明人： Carl-Heinz Struck , Ralf Schumacher
IPC分类号： C10B27/06 , F04F5/04 , C10B27/04 , C10B41/08
CPC分类号： F04F5/04 , C10B27/06
摘要： A spray nozzle for use in the elbow interconnecting a coke oven ascension pipe and a main, characterized in having frusto-conical nozzle orifices to generate sprays which commpletely cover the elbow cross section only when they reach the transition between the elbow and the coke oven main. The invention resides in the realization that in order to optimize the performance of the nozzle, there must be a specified relationship between the inlet diameters of the frusto-conical orifices, the outlet diameters of the orifices and the radial and circumferential distances between the centers of orifices arranged in concentric circles.
摘要翻译：一种用于弯头的喷嘴，其连接焦炉升降管和主体，其特征在于，具有截头圆锥形的喷嘴孔，以产生仅当它们到达弯头和焦炉主体之间的过渡时完全覆盖弯头横截面的喷雾。本发明的目的在于为了优化喷嘴的性能，必须在截头圆锥形孔口的入口直径，孔口的出口直径与中心之间的径向和圆周距离之间具有规定的关系排列成同心圆的孔。

50. 发明授权

US08764497B2 Electrical contact part 有权
标题翻译：电接触部分
公开(公告)号：US08764497B2
公开(公告)日：2014-07-01
申请号：US13808097
申请日：2011-07-13
申请人： Stephan Fehling , Georg Kulturidi , Matthias Niggemann , Klaus Pueschner , Michael Schnatwinkel , Ralf Schumacher , Klaus Wohlgemuth , Marco Waldhoff , Gerhard Eggert
发明人： Stephan Fehling , Georg Kulturidi , Matthias Niggemann , Klaus Pueschner , Michael Schnatwinkel , Ralf Schumacher , Klaus Wohlgemuth , Marco Waldhoff , Gerhard Eggert
IPC分类号： H01R4/48
CPC分类号： H01R13/113 , H01R9/2675 , H01R11/05 , H01R12/721 , H01R13/05 , H01R13/112
摘要： An electrical contact arrangement includes a planar conductive metal blank having sections that are foldable to define pairs of orthogonally arranged component contacts and bus blade contacts. Connected with a first pair of opposed side edges of a horizontal rectangular core section of the blank are a pair of rectangular component contact sections that are upwardly bent to define a pair of component contacts for receiving therebetween an electrical component, such as a printed circuit board. Connected with the orthogonally arranged second pair of opposed side edges of the core section are a pair of rectangular support sections that are bent downwardly, whereby a corresponding pair of bus blade contact sections connected with corresponding edges of the support sections extend in vertical parallel spaced relation to define a pair of bus blade contacts adapted for insertion between the downwardly bent support sections of a corresponding second electrical contact arrangement.
摘要翻译：电接触装置包括具有可折叠以限定成对的正交布置的部件触点和总线刀片触点的部分的平面导电金属坯料。与坯料的水平矩形芯部分的第一对相对的侧边缘连接有一对矩形部件接触部分，其被向上弯曲以限定一对部件接触件，用于在其间接纳电气部件，例如印刷电路板。与芯部分的正交布置的第二对相对的侧边缘连接的是一对向下弯曲的矩形支撑部分，由此与支撑部分的相应边缘连接的相应的一对母线片接触部分以垂直平行间隔的关系延伸以限定一对总线叶片触点，其适于插入相应的第二电接触装置的向下弯曲的支撑部分之间。

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